[article]
Titre : |
Autism spectrum disorders and the amplitude of auditory brainstem response wave I |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; Cecília ALMEIDA E SOUSA, Auteur |
Article en page(s) : |
p.1300-1305 |
Langues : |
Anglais (eng) |
Mots-clés : |
auditory brainstem response autism spectrum disorders hearing |
Index. décimale : |
PER Périodiques |
Résumé : |
To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. |
En ligne : |
http://dx.doi.org/10.1002/aur.1771 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 |
in Autism Research > 10-7 (July 2017) . - p.1300-1305
[article] Autism spectrum disorders and the amplitude of auditory brainstem response wave I [Texte imprimé et/ou numérique] / Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; Cecília ALMEIDA E SOUSA, Auteur . - p.1300-1305. Langues : Anglais ( eng) in Autism Research > 10-7 (July 2017) . - p.1300-1305
Mots-clés : |
auditory brainstem response autism spectrum disorders hearing |
Index. décimale : |
PER Périodiques |
Résumé : |
To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. |
En ligne : |
http://dx.doi.org/10.1002/aur.1771 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 |
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