Associations Between the 2nd to 4th Digit Ratio and Autism Spectrum Disorder in Population-Based Samples of Boys and Girls: Findings from the Study to Explore Early Development / Laura A. SCHIEVE in Journal of Autism and Developmental Disorders, 48-7 (July 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-7 (July 2018) . - p.2379-2395 Titre : Associations Between the 2nd to 4th Digit Ratio and Autism Spectrum Disorder in Population-Based Samples of Boys and Girls: Findings from the Study to Explore Early Development Type de document : Texte imprimé et/ou numérique Auteurs : Laura A. SCHIEVE, Auteur ; L. TIAN, Auteur ; N. DOWLING, Auteur ; Lisa A. CROEN, Auteur ; J. HOOVER-FONG, Auteur ; A. ALEXANDER, Auteur ; S. K. SHAPIRA, Auteur Article en page(s) : p.2379-2395 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Estradiol  Fetal development  Testosterone Index. décimale : PER Périodiques Résumé : The ratio of the index (2nd) finger to ring (4th) finger lengths (2D:4D) is a proxy for fetal testosterone and estradiol. Studies suggesting 2D:4D is inversely associated with autism spectrum disorder (ASD) in males were limited by lack of confounder and subgroup assessments. Studies of females are sparse. We examined associations between ASD and 2D:4D among children in the Study to Explore Early Development; we considered case subgroups and numerous potential demographic and maternal-perinatal health confounders. We observed a modest inverse association between ASD and right-hand 2D:4D in males; subgroup analyses indicated associations were limited to ASD cases with birth defects/genetic syndromes or dysmorphic features. We observed a positive association between ASD and left-hand 2D:4D in females, overall and within most case subgroups. En ligne : http://dx.doi.org/10.1007/s10803-018-3495-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 [article] Associations Between the 2nd to 4th Digit Ratio and Autism Spectrum Disorder in Population-Based Samples of Boys and Girls: Findings from the Study to Explore Early Development [Texte imprimé et/ou numérique] / Laura A. SCHIEVE, Auteur ; L. TIAN, Auteur ; N. DOWLING, Auteur ; Lisa A. CROEN, Auteur ; J. HOOVER-FONG, Auteur ; A. ALEXANDER, Auteur ; S. K. SHAPIRA, Auteur . - p.2379-2395. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-7 (July 2018) . - p.2379-2395 Mots-clés : Autism spectrum disorder  Estradiol  Fetal development  Testosterone Index. décimale : PER Périodiques Résumé : The ratio of the index (2nd) finger to ring (4th) finger lengths (2D:4D) is a proxy for fetal testosterone and estradiol. Studies suggesting 2D:4D is inversely associated with autism spectrum disorder (ASD) in males were limited by lack of confounder and subgroup assessments. Studies of females are sparse. We examined associations between ASD and 2D:4D among children in the Study to Explore Early Development; we considered case subgroups and numerous potential demographic and maternal-perinatal health confounders. We observed a modest inverse association between ASD and right-hand 2D:4D in males; subgroup analyses indicated associations were limited to ASD cases with birth defects/genetic syndromes or dysmorphic features. We observed a positive association between ASD and left-hand 2D:4D in females, overall and within most case subgroups. En ligne : http://dx.doi.org/10.1007/s10803-018-3495-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367

Screening for Autism with the SRS and SCQ: Variations across Demographic, Developmental and Behavioral Factors in Preschool Children / E. J. MOODY in Journal of Autism and Developmental Disorders, 47-11 (November 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3550-3561 Titre : Screening for Autism with the SRS and SCQ: Variations across Demographic, Developmental and Behavioral Factors in Preschool Children Type de document : Texte imprimé et/ou numérique Auteurs : E. J. MOODY, Auteur ; N. REYES, Auteur ; C. LEDBETTER, Auteur ; Lisa D. WIGGINS, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; A. ALEXANDER, Auteur ; S. JACKSON, Auteur ; L. C. LEE, Auteur ; S. E. LEVY, Auteur ; S. A. ROSENBERG, Auteur Article en page(s) : p.3550-3561 Langues : Anglais (eng) Mots-clés : Autism  Demographics  Development  Maternal education  Screener Index. décimale : PER Périodiques Résumé : The Social Communication Questionnaire (SCQ) and the Social Responsiveness Scales (SRS) are commonly used screeners for autism spectrum disorder (ASD). Data from the Study to Explore Early Development were used to examine variations in the performance of these instruments by child characteristics and family demographics. For both instruments, specificity decreased as maternal education and family income decreased. Specificity was decreased with lower developmental functioning and higher behavior problems. This suggests that the false positive rates of the SRS and the SCQ are associated with child characteristics and family demographic factors. There is a need for ASD screeners that perform well across socioeconomic and child characteristics. Clinicians should be mindful of differential performance of these instruments in various groups of children. En ligne : http://dx.doi.org/10.1007/s10803-017-3255-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325 [article] Screening for Autism with the SRS and SCQ: Variations across Demographic, Developmental and Behavioral Factors in Preschool Children [Texte imprimé et/ou numérique] / E. J. MOODY, Auteur ; N. REYES, Auteur ; C. LEDBETTER, Auteur ; Lisa D. WIGGINS, Auteur ; Carolyn G. DIGUISEPPI, Auteur ; A. ALEXANDER, Auteur ; S. JACKSON, Auteur ; L. C. LEE, Auteur ; S. E. LEVY, Auteur ; S. A. ROSENBERG, Auteur . - p.3550-3561. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3550-3561 Mots-clés : Autism  Demographics  Development  Maternal education  Screener Index. décimale : PER Périodiques Résumé : The Social Communication Questionnaire (SCQ) and the Social Responsiveness Scales (SRS) are commonly used screeners for autism spectrum disorder (ASD). Data from the Study to Explore Early Development were used to examine variations in the performance of these instruments by child characteristics and family demographics. For both instruments, specificity decreased as maternal education and family income decreased. Specificity was decreased with lower developmental functioning and higher behavior problems. This suggests that the false positive rates of the SRS and the SCQ are associated with child characteristics and family demographic factors. There is a need for ASD screeners that perform well across socioeconomic and child characteristics. Clinicians should be mindful of differential performance of these instruments in various groups of children. En ligne : http://dx.doi.org/10.1007/s10803-017-3255-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325

---

1 (1 - 2 / 2)