[article] 
inJournal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.114-139

Titre :	Research Review: Pediatric anxiety disorders - what have we learnt in the last 10 years?
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Jeffrey R. STRAWN, Auteur ; Lu LU, Auteur ; Tara S. PERIS, Auteur ; Amir LEVINE, Auteur ; John T. WALKUP, Auteur
Année de publication :	2021
Article en page(s) :	p.114-139
Langues :	Anglais (eng)
Mots-clés :	Generalized anxiety disorder  Sri)  fMRI  pharmacogenomics  selective serotonin reuptake inhibitor (SSRI  separation anxiety disorder
Index. décimale :	PER Périodiques
Résumé :	BACKGROUND: Anxiety disorders first emerge during the critical developmental periods of childhood and adolescence. This review synthesizes recent findings on the prevalence, risk factors, and course of the anxiety disorders; and their neurobiology and treatment. METHODS: For this review, searches were conducted using PubMed, PsycINFO, and clinicaltrials.gov. Findings related to the epidemiology, neurobiology, risk factors, and treatment of pediatric anxiety disorders were then summarized. FINDINGS: Anxiety disorders are high prevalence, and early-onset conditions associated with multiple risk factors including early inhibited temperament, environment stress, and structural and functional abnormalities in the prefrontal-amygdala circuitry as well as the default mode and salience networks. The anxiety disorders are effectively treated with cognitive behavioral therapy (CBT), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs). CONCLUSIONS: Anxiety disorders are high prevalence, early-onset conditions associated with a distinct neurobiological fingerprint, and are consistently responsive to treatment. Questions remain regarding who is at risk of developing anxiety disorders as well as the way in which neurobiology predicts treatment response.
En ligne :	http://dx.doi.org/10.1111/jcpp.13262
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440

[article] Research Review: Pediatric anxiety disorders - what have we learnt in the last 10 years? [Texte imprimé et/ou numérique] / Jeffrey R. STRAWN, Auteur ; Lu LU, Auteur ; Tara S. PERIS, Auteur ; Amir LEVINE, Auteur ; John T. WALKUP, Auteur . - 2021 . - p.114-139.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-2 (February 2021) . - p.114-139

Mots-clés :	Generalized anxiety disorder  Sri)  fMRI  pharmacogenomics  selective serotonin reuptake inhibitor (SSRI  separation anxiety disorder
Index. décimale :	PER Périodiques
Résumé :	BACKGROUND: Anxiety disorders first emerge during the critical developmental periods of childhood and adolescence. This review synthesizes recent findings on the prevalence, risk factors, and course of the anxiety disorders; and their neurobiology and treatment. METHODS: For this review, searches were conducted using PubMed, PsycINFO, and clinicaltrials.gov. Findings related to the epidemiology, neurobiology, risk factors, and treatment of pediatric anxiety disorders were then summarized. FINDINGS: Anxiety disorders are high prevalence, and early-onset conditions associated with multiple risk factors including early inhibited temperament, environment stress, and structural and functional abnormalities in the prefrontal-amygdala circuitry as well as the default mode and salience networks. The anxiety disorders are effectively treated with cognitive behavioral therapy (CBT), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs). CONCLUSIONS: Anxiety disorders are high prevalence, early-onset conditions associated with a distinct neurobiological fingerprint, and are consistently responsive to treatment. Questions remain regarding who is at risk of developing anxiety disorders as well as the way in which neurobiology predicts treatment response.
En ligne :	http://dx.doi.org/10.1111/jcpp.13262
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440