Anxiety symptom trajectories from treatment to 5- to 12-year follow-up across childhood and adolescence / Sunhye BAI in Journal of Child Psychology and Psychiatry, 64-9 (September 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-9 (September 2023) . - p.1336-1345 Titre : Anxiety symptom trajectories from treatment to 5- to 12-year follow-up across childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Sunhye BAI, Auteur ; Benjamin ROLON-ARROYO, Auteur ; John T. WALKUP, Auteur ; Philip C. KENDALL, Auteur ; Golda S. GINSBURG, Auteur ; Courtney P. KEETON, Auteur ; Anne Marie ALBANO, Auteur ; Scott N. COMPTON, Auteur ; Dara SAKOLSKY, Auteur ; John PIACENTINI, Auteur ; Tara S. PERIS, Auteur Article en page(s) : p.1336-1345 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Objective The current study examined trajectories of anxiety during (a) acute treatment and (b) extended follow-up to better characterize the long-term symptom trajectories of youth who received evidence-based intervention for anxiety disorders using a person-centered approach. Method Participants were 319 youth (age 7-17?years at enrollment), who participated in a multicenter randomized controlled trial for the treatment of pediatric anxiety disorders, Child/Adolescent Anxiety Multimodal Study, and a 4-year naturalistic follow-up, Child/Adolescent Anxiety Multimodal Extended Long-term Study, an average of 6.5?years later. Using growth mixture modeling, the study identified distinct trajectories of anxiety across acute treatment (Weeks 0-12), posttreatment (Weeks 12-36), and the 4-year-long follow-up, and identified baseline predictors of these trajectories. Results Three nonlinear anxiety trajectories emerged: "short-term responders" who showed rapid treatment response but had higher levels of anxiety during the extended follow-up; "durable responders" who sustained treatment gains; and "delayed remitters" who did not show an initial response to treatment, but showed low levels of anxiety during the maintenance and extended follow-up periods. Worse anxiety severity and better family functioning at baseline predicted membership in the delayed remitters group. Caregiver strain differentiated short-term responders from durable responders. Conclusions Findings suggest that initial response to treatment does not guarantee sustained treatment gains over time for some youth. Future follow-up studies that track treated youth across key developmental transitions and in the context of changing social environments are needed to inform best practices for the long-term management of anxiety. En ligne : https://doi.org/10.1111/jcpp.13796 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 [article] Anxiety symptom trajectories from treatment to 5- to 12-year follow-up across childhood and adolescence [Texte imprimé et/ou numérique] / Sunhye BAI, Auteur ; Benjamin ROLON-ARROYO, Auteur ; John T. WALKUP, Auteur ; Philip C. KENDALL, Auteur ; Golda S. GINSBURG, Auteur ; Courtney P. KEETON, Auteur ; Anne Marie ALBANO, Auteur ; Scott N. COMPTON, Auteur ; Dara SAKOLSKY, Auteur ; John PIACENTINI, Auteur ; Tara S. PERIS, Auteur . - p.1336-1345. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-9 (September 2023) . - p.1336-1345 Index. décimale : PER Périodiques Résumé : Objective The current study examined trajectories of anxiety during (a) acute treatment and (b) extended follow-up to better characterize the long-term symptom trajectories of youth who received evidence-based intervention for anxiety disorders using a person-centered approach. Method Participants were 319 youth (age 7-17?years at enrollment), who participated in a multicenter randomized controlled trial for the treatment of pediatric anxiety disorders, Child/Adolescent Anxiety Multimodal Study, and a 4-year naturalistic follow-up, Child/Adolescent Anxiety Multimodal Extended Long-term Study, an average of 6.5?years later. Using growth mixture modeling, the study identified distinct trajectories of anxiety across acute treatment (Weeks 0-12), posttreatment (Weeks 12-36), and the 4-year-long follow-up, and identified baseline predictors of these trajectories. Results Three nonlinear anxiety trajectories emerged: "short-term responders" who showed rapid treatment response but had higher levels of anxiety during the extended follow-up; "durable responders" who sustained treatment gains; and "delayed remitters" who did not show an initial response to treatment, but showed low levels of anxiety during the maintenance and extended follow-up periods. Worse anxiety severity and better family functioning at baseline predicted membership in the delayed remitters group. Caregiver strain differentiated short-term responders from durable responders. Conclusions Findings suggest that initial response to treatment does not guarantee sustained treatment gains over time for some youth. Future follow-up studies that track treated youth across key developmental transitions and in the context of changing social environments are needed to inform best practices for the long-term management of anxiety. En ligne : https://doi.org/10.1111/jcpp.13796 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512

Candidate gene associations with withdrawn behavior / David H. RUBIN in Journal of Child Psychology and Psychiatry, 54-12 (December 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1337-1345 Titre : Candidate gene associations with withdrawn behavior Type de document : Texte imprimé et/ou numérique Auteurs : David H. RUBIN, Auteur ; Robert R. ALTHOFF, Auteur ; Erik A. EHLI, Auteur ; Gareth E. DAVIES, Auteur ; David C. RETTEW, Auteur ; Eileen T. CREHAN, Auteur ; John T. WALKUP, Auteur ; James J. HUDZIAK, Auteur Article en page(s) : p.1337-1345 Langues : Anglais (eng) Mots-clés : Withdrawn behavior  Child Behavior Checklist  Adult Self-Report  behavioral inhibition  social withdrawal Index. décimale : PER Périodiques Résumé : Background Social withdrawal is a core neuropsychiatric phenomenon in developmental psychopathology. Its presence predicts psychopathology across many domains, including depression, psychosis, autism, anxiety, and suicide. Withdrawn behavior is highly heritable, persistent, and characteristically worsens without intervention. To date, few studies have successfully identified genetic associations with withdrawn behavior, despite the abundance of evidence of its heritability. This may be due to reliance of categorical over dimensional measures of the behaviorally inhibited phenotype. The aim of this study is to identify associations between known psychiatric candidate genes and a dimensionally derived measure of withdrawn behavior. Methods Genetic information was collected on 20 single-nucleotide polymorphisms (SNPs) from a custom-designed SNP chip and TAQMAN arrays of 4 variable number of tandem repeat (VNTR) genes for 551 individuals from 187 families. Linear mixed modeling was employed to examine the relationship between genotypes of interest and Child Behavior Checklist (CBCL) Withdrawn Behavior Subscale Score (WBS) while controlling for gender and age through multiple linear regressions. Results Withdrawn behavior was highly associated with polymorphism rs6314 of the serotonin receptor 2A (HTR2A) [p = .009, estimate = 0.310 (bootstrap 95% CI 0.155–0.448), bootstrap p = .001] and rs1800544 of the alpha 2-adrenergic (ADRA2A) [p = .001, estimate = ?0.310 (bootstrap 95% CI ?0.479 to ?0.126), bootstrap p = .001] genes after correction for gender and age. The association between withdrawn behavior and ADRA2A was stronger for younger children. Conclusions HTR2A and ADRA2A genes are associated with withdrawn behavior. This reinforces the role of catecholaminergic genes in the heritability of withdrawn behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12108 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 [article] Candidate gene associations with withdrawn behavior [Texte imprimé et/ou numérique] / David H. RUBIN, Auteur ; Robert R. ALTHOFF, Auteur ; Erik A. EHLI, Auteur ; Gareth E. DAVIES, Auteur ; David C. RETTEW, Auteur ; Eileen T. CREHAN, Auteur ; John T. WALKUP, Auteur ; James J. HUDZIAK, Auteur . - p.1337-1345. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-12 (December 2013) . - p.1337-1345 Mots-clés : Withdrawn behavior  Child Behavior Checklist  Adult Self-Report  behavioral inhibition  social withdrawal Index. décimale : PER Périodiques Résumé : Background Social withdrawal is a core neuropsychiatric phenomenon in developmental psychopathology. Its presence predicts psychopathology across many domains, including depression, psychosis, autism, anxiety, and suicide. Withdrawn behavior is highly heritable, persistent, and characteristically worsens without intervention. To date, few studies have successfully identified genetic associations with withdrawn behavior, despite the abundance of evidence of its heritability. This may be due to reliance of categorical over dimensional measures of the behaviorally inhibited phenotype. The aim of this study is to identify associations between known psychiatric candidate genes and a dimensionally derived measure of withdrawn behavior. Methods Genetic information was collected on 20 single-nucleotide polymorphisms (SNPs) from a custom-designed SNP chip and TAQMAN arrays of 4 variable number of tandem repeat (VNTR) genes for 551 individuals from 187 families. Linear mixed modeling was employed to examine the relationship between genotypes of interest and Child Behavior Checklist (CBCL) Withdrawn Behavior Subscale Score (WBS) while controlling for gender and age through multiple linear regressions. Results Withdrawn behavior was highly associated with polymorphism rs6314 of the serotonin receptor 2A (HTR2A) [p = .009, estimate = 0.310 (bootstrap 95% CI 0.155–0.448), bootstrap p = .001] and rs1800544 of the alpha 2-adrenergic (ADRA2A) [p = .001, estimate = ?0.310 (bootstrap 95% CI ?0.479 to ?0.126), bootstrap p = .001] genes after correction for gender and age. The association between withdrawn behavior and ADRA2A was stronger for younger children. Conclusions HTR2A and ADRA2A genes are associated with withdrawn behavior. This reinforces the role of catecholaminergic genes in the heritability of withdrawn behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12108 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219

Cas 1.5 : Agité et distrait / Robert HASKELL

Public ISBD in DSM-5®. Cas cliniques / John W. BARNHILL Titre : Cas 1.5 : Agité et distrait Type de document : Texte imprimé et/ou numérique Auteurs : Robert HASKELL, Auteur ; John T. WALKUP, Auteur Année de publication : 2016 Importance : p.13-14 Langues : Français (fre) Index. décimale : SCI-A SCI-A - Classifications Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=469 in DSM-5®. Cas cliniques / John W. BARNHILL Cas 1.5 : Agité et distrait [Texte imprimé et/ou numérique] / Robert HASKELL, Auteur ; John T. WALKUP, Auteur . - 2016 . - p.13-14. Langues : Français (fre) Index. décimale : SCI-A SCI-A - Classifications Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=469

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Dysregulated Irritability as a Window on Young Children's Psychiatric Risk: Transdiagnostic Effects via the Family Check-Up / J. D. SMITH in Development and Psychopathology, 31-5 (December 2019)  

Public ISBD [article]  inDevelopment and Psychopathology > 31-5 (December 2019) . - p.1887-1899 Titre : Dysregulated Irritability as a Window on Young Children's Psychiatric Risk: Transdiagnostic Effects via the Family Check-Up Type de document : Texte imprimé et/ou numérique Auteurs : J. D. SMITH, Auteur ; Lauren S. WAKSCHLAG, Auteur ; S. KROGH-JESPERSEN, Auteur ; John T. WALKUP, Auteur ; M. N. WILSON, Auteur ; T. J. DISHION, Auteur ; D. S. SHAW, Auteur Année de publication : 2019 Article en page(s) : p.1887-1899 Langues : Anglais (eng) Mots-clés : Family Check-Up  early childhood  irritability  mental health  parent training  prevention  transdiagnostic Index. décimale : PER Périodiques Résumé : Building on prior work using Tom Dishion's Family Check-Up, the current article examined intervention effects on dysregulated irritability in early childhood. Dysregulated irritability, defined as reactive and intense response to frustration, and prolonged angry mood, is an ideal marker of neurodevelopmental vulnerability to later psychopathology because it is a transdiagnostic indicator of decrements in self-regulation that are measurable in the first years of life that have lifelong implications for health and disease. This study is perhaps the first randomized trial to examine the direct effects of an evidence- and family-based intervention, the Family Check-Up (FCU), on irritability in early childhood and the effects of reductions in irritability on later risk of child internalizing and externalizing symptomatology. Data from the geographically and sociodemographically diverse multisite Early Steps randomized prevention trial were used. Path modeling revealed intervention effects on irritability at age 4, which predicted lower externalizing and internalizing symptoms at age 10.5. Results indicate that family-based programs initiated in early childhood can reduce early childhood irritability and later risk for psychopathology. This holds promise for earlier identification and prevention approaches that target transdiagnostic pathways. Implications for future basic and prevention research are discussed. En ligne : http://dx.doi.org/10.1017/s0954579419000816 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412 [article] Dysregulated Irritability as a Window on Young Children's Psychiatric Risk: Transdiagnostic Effects via the Family Check-Up [Texte imprimé et/ou numérique] / J. D. SMITH, Auteur ; Lauren S. WAKSCHLAG, Auteur ; S. KROGH-JESPERSEN, Auteur ; John T. WALKUP, Auteur ; M. N. WILSON, Auteur ; T. J. DISHION, Auteur ; D. S. SHAW, Auteur . - 2019 . - p.1887-1899. Langues : Anglais (eng) in Development and Psychopathology > 31-5 (December 2019) . - p.1887-1899 Mots-clés : Family Check-Up  early childhood  irritability  mental health  parent training  prevention  transdiagnostic Index. décimale : PER Périodiques Résumé : Building on prior work using Tom Dishion's Family Check-Up, the current article examined intervention effects on dysregulated irritability in early childhood. Dysregulated irritability, defined as reactive and intense response to frustration, and prolonged angry mood, is an ideal marker of neurodevelopmental vulnerability to later psychopathology because it is a transdiagnostic indicator of decrements in self-regulation that are measurable in the first years of life that have lifelong implications for health and disease. This study is perhaps the first randomized trial to examine the direct effects of an evidence- and family-based intervention, the Family Check-Up (FCU), on irritability in early childhood and the effects of reductions in irritability on later risk of child internalizing and externalizing symptomatology. Data from the geographically and sociodemographically diverse multisite Early Steps randomized prevention trial were used. Path modeling revealed intervention effects on irritability at age 4, which predicted lower externalizing and internalizing symptoms at age 10.5. Results indicate that family-based programs initiated in early childhood can reduce early childhood irritability and later risk for psychopathology. This holds promise for earlier identification and prevention approaches that target transdiagnostic pathways. Implications for future basic and prevention research are discussed. En ligne : http://dx.doi.org/10.1017/s0954579419000816 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412

Factor Structure and Psychometric Properties of the Children's Negative Cognitive Error Questionnaire with a Clinically Depressed Adolescent Sample / Julie NEWMAN KINGERY in Journal of Clinical Child & Adolescent Psychology, 38-6 (November-December 2009)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 38-6 (November-December 2009) . - p.768-780 Titre : Factor Structure and Psychometric Properties of the Children's Negative Cognitive Error Questionnaire with a Clinically Depressed Adolescent Sample Type de document : Texte imprimé et/ou numérique Auteurs : Julie NEWMAN KINGERY, Auteur ; John S. MARCH, Auteur ; Mark A. REINECKE, Auteur ; Hayden O. KEPLEY, Auteur ; Golda S. GINSBURG, Auteur ; John T. WALKUP, Auteur ; Susan G. SILVA, Auteur ; Rick H. HOYLE, Auteur Année de publication : 2009 Article en page(s) : p.768-780 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The factor structure and psychometric properties of the Children's Negative Cognitive Error Questionnaire (CNCEQ) were examined with 427 adolescents ages 12 to 18 (193 boys) with current major depressive disorder. Results of confirmatory factor analysis supported a four-factor model comprised of three content area factors (i.e., social, academic, athletic) and a general factor. Internal consistencies ranged between .84 and .94 for the total and three content area scores. Girls scored significantly higher than boys on all factors, but no age differences on the factors were found. Convergent and discriminant validity of the CNCEQ were supported. Results did not support the original subscales organized by type of cognitive distortion (e.g., catastrophizing, overgeneralizing). Findings indicated that the CNCEQ would be a useful clinical tool for assessing cognitive symptoms within relevant domains of functioning (e.g., social, academic) of depressed youth. En ligne : http://dx.doi.org/10.1080/15374410903297130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=880 [article] Factor Structure and Psychometric Properties of the Children's Negative Cognitive Error Questionnaire with a Clinically Depressed Adolescent Sample [Texte imprimé et/ou numérique] / Julie NEWMAN KINGERY, Auteur ; John S. MARCH, Auteur ; Mark A. REINECKE, Auteur ; Hayden O. KEPLEY, Auteur ; Golda S. GINSBURG, Auteur ; John T. WALKUP, Auteur ; Susan G. SILVA, Auteur ; Rick H. HOYLE, Auteur . - 2009 . - p.768-780. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 38-6 (November-December 2009) . - p.768-780 Index. décimale : PER Périodiques Résumé : The factor structure and psychometric properties of the Children's Negative Cognitive Error Questionnaire (CNCEQ) were examined with 427 adolescents ages 12 to 18 (193 boys) with current major depressive disorder. Results of confirmatory factor analysis supported a four-factor model comprised of three content area factors (i.e., social, academic, athletic) and a general factor. Internal consistencies ranged between .84 and .94 for the total and three content area scores. Girls scored significantly higher than boys on all factors, but no age differences on the factors were found. Convergent and discriminant validity of the CNCEQ were supported. Results did not support the original subscales organized by type of cognitive distortion (e.g., catastrophizing, overgeneralizing). Findings indicated that the CNCEQ would be a useful clinical tool for assessing cognitive symptoms within relevant domains of functioning (e.g., social, academic) of depressed youth. En ligne : http://dx.doi.org/10.1080/15374410903297130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=880

Gut Microbiota and Autism: Key Concepts and Findings / Helen T. DING in Journal of Autism and Developmental Disorders, 47-2 (February 2017)  

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Research Review: Pediatric anxiety disorders - what have we learnt in the last 10 years? / Jeffrey R. STRAWN in Journal of Child Psychology and Psychiatry, 62-2 (February 2021)  

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Symptom-specific effects of cognitive-behavioral therapy, sertraline, and their combination in a large randomized controlled trial of pediatric anxiety disorders / Matti CERVIN in Journal of Child Psychology and Psychiatry, 61-4 (April 2020)  

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