[article]
| Titre : |
Comparison of Serum VEGF, IGF-1, and HIF-1α Levels in Children with Autism Spectrum Disorder and Healthy Controls |
| Type de document : |
texte imprimé |
| Auteurs : |
F. ŞIMŞEK, Auteur ; Ü IŞIK, Auteur ; E. AKTEPE, Auteur ; F. KILIÇ, Auteur ; F. B. ŞIRIN, Auteur ; M. BOZKURT, Auteur |
| Article en page(s) : |
p.3564-3574 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism Spectrum Disorder/diagnosis Child Humans Hypoxia-Inducible Factor 1, alpha Subunit/blood Insulin-Like Growth Factor I/analysis Vascular Endothelial Growth Factor A/blood Autism spectrum disorder Hif-1? Igf-1 Vegf |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The aim of this study was to determine whether serum VEGF, IGF-1, and HIF-1α levels differed between Autism Spectrum Disorder (ASD) patients and healthy controls. A total of 40 children with ASD and 40 healthy controls aged 4-12 years were included. Serum levels of VEGF, IGF-1, and HIF-1α were measured using commercial enzyme-linked immunosorbent assay kits. Serum IGF-1 levels were found to be statistically significantly higher in the ASD group than in the control group. Serum HIF-1α levels were borderline significantly lower in the ASD group. There was no statistically significant difference in serum VEGF levels between the two groups. IGF-1 and HIF-1α may play a potential role in the etiopathogenesis of ASD. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-020-04820-w |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 |
in Journal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3564-3574
|  |
Comparison of Serum VEGF, IGF-1, and HIF-1α Levels in Children with Autism Spectrum Disorder and Healthy Controls in Journal of Autism and Developmental Disorders, 51-10 (October 2021)
