Organization of brain networks governed by long-range connections index autistic traits in the general population / P. BARTTFELD in Journal of Neurodevelopmental Disorders, 5-1 (December 2013)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 5-1 (December 2013) . - p.16 Titre : Organization of brain networks governed by long-range connections index autistic traits in the general population Type de document : Texte imprimé et/ou numérique Auteurs : P. BARTTFELD, Auteur ; L. AMORUSO, Auteur ; J. AIS, Auteur ; S. CUKIER, Auteur ; L. BAVASSI, Auteur ; A. TOMIO, Auteur ; F. MANES, Auteur ; A. IBANEZ, Auteur ; M. SIGMAN, Auteur Article en page(s) : p.16 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : BACKGROUND: The dimensional approach to autism spectrum disorder (ASD) considers ASD as the extreme of a dimension traversing through the entire population. We explored the potential utility of electroencephalography (EEG) functional connectivity as a biomarker. We hypothesized that individual differences in autistic traits of typical subjects would involve a long-range connectivity diminution within the delta band. METHODS: Resting-state EEG functional connectivity was measured for 74 neurotypical subjects. All participants also provided a questionnaire (Social Responsiveness Scale, SRS) that was completed by an informant who knows the participant in social settings. We conducted multivariate regression between the SRS score and functional connectivity in all EEG frequency bands. We explored modulations of network graph metrics characterizing the optimality of a network using the SRS score. RESULTS: Our results show a decay in functional connectivity mainly within the delta and theta bands (the lower part of the EEG spectrum) associated with an increasing number of autistic traits. When inspecting the impact of autistic traits on the global organization of the functional network, we found that the optimal properties of the network are inversely related to the number of autistic traits, suggesting that the autistic dimension, throughout the entire population, modulates the efficiency of functional brain networks. CONCLUSIONS: EEG functional connectivity at low frequencies and its associated network properties may be associated with some autistic traits in the general population. En ligne : http://dx.doi.org/10.1186/1866-1955-5-16 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=345 [article] Organization of brain networks governed by long-range connections index autistic traits in the general population [Texte imprimé et/ou numérique] / P. BARTTFELD, Auteur ; L. AMORUSO, Auteur ; J. AIS, Auteur ; S. CUKIER, Auteur ; L. BAVASSI, Auteur ; A. TOMIO, Auteur ; F. MANES, Auteur ; A. IBANEZ, Auteur ; M. SIGMAN, Auteur . - p.16. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 5-1 (December 2013) . - p.16 Index. décimale : PER Périodiques Résumé : BACKGROUND: The dimensional approach to autism spectrum disorder (ASD) considers ASD as the extreme of a dimension traversing through the entire population. We explored the potential utility of electroencephalography (EEG) functional connectivity as a biomarker. We hypothesized that individual differences in autistic traits of typical subjects would involve a long-range connectivity diminution within the delta band. METHODS: Resting-state EEG functional connectivity was measured for 74 neurotypical subjects. All participants also provided a questionnaire (Social Responsiveness Scale, SRS) that was completed by an informant who knows the participant in social settings. We conducted multivariate regression between the SRS score and functional connectivity in all EEG frequency bands. We explored modulations of network graph metrics characterizing the optimality of a network using the SRS score. RESULTS: Our results show a decay in functional connectivity mainly within the delta and theta bands (the lower part of the EEG spectrum) associated with an increasing number of autistic traits. When inspecting the impact of autistic traits on the global organization of the functional network, we found that the optimal properties of the network are inversely related to the number of autistic traits, suggesting that the autistic dimension, throughout the entire population, modulates the efficiency of functional brain networks. CONCLUSIONS: EEG functional connectivity at low frequencies and its associated network properties may be associated with some autistic traits in the general population. En ligne : http://dx.doi.org/10.1186/1866-1955-5-16 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=345

Use of allied-health services and medication among adults with ASD in Latin America / A. TORRES in Autism Research, 14-10 (October 2021)  

Public ISBD [article]  inAutism Research > 14-10 (October 2021) . - p.2200-2211 Titre : Use of allied-health services and medication among adults with ASD in Latin America Type de document : Texte imprimé et/ou numérique Auteurs : A. TORRES, Auteur ; D. LECUSAY, Auteur ; D. VALDEZ, Auteur ; A. ROSOLI, Auteur ; G. GARRIDO, Auteur ; S. CUKIER, Auteur ; C. S. PAULA, Auteur ; R. GARCIA, Auteur ; A. RATTAZZI, Auteur ; C. MONTIEL-NAVA, Auteur Article en page(s) : p.2200-2211 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/drug therapy  Autistic Disorder  Caregivers  Health Services  Humans  Latin America  Hispanics  allied health  autism  autism medication  health disparities Index. décimale : PER Périodiques Résumé : ASD is a neurodevelopmental disorder that affects people across the entire lifespan, yet most of the research identifying the health and medical needs for autistic individuals have been among minors. As individuals with ASD transition to emerging adulthood, the services, already limited, become less available. This study aimed to identify the use of services for Latin American adults on the spectrum. We surveyed 295 caregivers of adults with ASD from six Latin American countries. Comparing the results for all the possible services observed in this study, the adults in our sample were primarily underserved: 84.4%-95.9% were receiving zero hours per week, 3.7%-12.9% 1%-10 h, 0%-1.7% 11-20, and only 0%-1% above 20?h of services. Almost half of the sample used medication, and neurologists were the most consulted health providers. Next to inexistent health care usage in Latin American adults with ASD highlights socioeconomic and health disparities in service provision for ASD in the region. The lack of services places adults with ASD in Latin America at a higher risk of worse symptom severity than autistic adults from regions with broader access to services. LAY SUMMARY: This study aimed to identify the quantity of services received by adults with autism in Latin America. Most of our sample was not receiving health services yet almost half had access to medication. This could mean that adults with autism in Latin America are at higher risk for poorer health. En ligne : http://dx.doi.org/10.1002/aur.2583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Use of allied-health services and medication among adults with ASD in Latin America [Texte imprimé et/ou numérique] / A. TORRES, Auteur ; D. LECUSAY, Auteur ; D. VALDEZ, Auteur ; A. ROSOLI, Auteur ; G. GARRIDO, Auteur ; S. CUKIER, Auteur ; C. S. PAULA, Auteur ; R. GARCIA, Auteur ; A. RATTAZZI, Auteur ; C. MONTIEL-NAVA, Auteur . - p.2200-2211. Langues : Anglais (eng) in Autism Research > 14-10 (October 2021) . - p.2200-2211 Mots-clés : Adult  Autism Spectrum Disorder/drug therapy  Autistic Disorder  Caregivers  Health Services  Humans  Latin America  Hispanics  allied health  autism  autism medication  health disparities Index. décimale : PER Périodiques Résumé : ASD is a neurodevelopmental disorder that affects people across the entire lifespan, yet most of the research identifying the health and medical needs for autistic individuals have been among minors. As individuals with ASD transition to emerging adulthood, the services, already limited, become less available. This study aimed to identify the use of services for Latin American adults on the spectrum. We surveyed 295 caregivers of adults with ASD from six Latin American countries. Comparing the results for all the possible services observed in this study, the adults in our sample were primarily underserved: 84.4%-95.9% were receiving zero hours per week, 3.7%-12.9% 1%-10 h, 0%-1.7% 11-20, and only 0%-1% above 20?h of services. Almost half of the sample used medication, and neurologists were the most consulted health providers. Next to inexistent health care usage in Latin American adults with ASD highlights socioeconomic and health disparities in service provision for ASD in the region. The lack of services places adults with ASD in Latin America at a higher risk of worse symptom severity than autistic adults from regions with broader access to services. LAY SUMMARY: This study aimed to identify the quantity of services received by adults with autism in Latin America. Most of our sample was not receiving health services yet almost half had access to medication. This could mean that adults with autism in Latin America are at higher risk for poorer health. En ligne : http://dx.doi.org/10.1002/aur.2583 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

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