Accelerated epigenetic aging at birth interacts with parenting hostility to predict child temperament and subsequent psychological symptoms / Erika M. MANCZAK in Development and Psychopathology, 35-1 (February 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-1 (February 2023) . - p.109-118 Titre : Accelerated epigenetic aging at birth interacts with parenting hostility to predict child temperament and subsequent psychological symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Erika M. MANCZAK, Auteur ; Samantha R. SCOTT, Auteur ; Summer N. MILLWOOD, Auteur Article en page(s) : p.109-118 Langues : Anglais (eng) Mots-clés : epigenetics  methylation  parenting  psychopathology symptoms  temperament Index. décimale : PER Périodiques Résumé : In an effort to elucidate new factors that may contribute to developmental psychopathology, the current study examined whether accelerated epigenetic aging at birth related to children's differential susceptibility to the effects of aversive parenting on early emerging mental health risk. Using data from a multiethnic birth cohort, the interaction between Horvath's methylation age in umbilical cord blood and hostile parenting behaviors was examined in relation to perceptions of infant's temperament at 6 months and to children's psychological symptoms at 3 years in 154 families. Results broadly revealed that children with higher levels of accelerated methylation aging evinced more unpredictable temperaments and more psychological symptoms if their mothers reported more hostile parenting, but showed fewer difficulties if mothers engaged in less hostile parenting; children with lower levels of accelerated methylation age did not show associations between hostility and temperament or psychological symptoms. Effects were not accounted for by gestational age at birth, demographic factors, or the distribution of cell subtypes. These findings suggest that accelerated epigenetic age may function as a form of differential susceptibility, signaling increased risk for psychopathology in more aversive contexts but decreased risk in less aversive early environments. Taken together, they point to a novel biological process to consider within risk for psychopathology. En ligne : https://doi.org/10.1017/S0954579421000614 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Accelerated epigenetic aging at birth interacts with parenting hostility to predict child temperament and subsequent psychological symptoms [Texte imprimé et/ou numérique] / Erika M. MANCZAK, Auteur ; Samantha R. SCOTT, Auteur ; Summer N. MILLWOOD, Auteur . - p.109-118. Langues : Anglais (eng) in Development and Psychopathology > 35-1 (February 2023) . - p.109-118 Mots-clés : epigenetics  methylation  parenting  psychopathology symptoms  temperament Index. décimale : PER Périodiques Résumé : In an effort to elucidate new factors that may contribute to developmental psychopathology, the current study examined whether accelerated epigenetic aging at birth related to children's differential susceptibility to the effects of aversive parenting on early emerging mental health risk. Using data from a multiethnic birth cohort, the interaction between Horvath's methylation age in umbilical cord blood and hostile parenting behaviors was examined in relation to perceptions of infant's temperament at 6 months and to children's psychological symptoms at 3 years in 154 families. Results broadly revealed that children with higher levels of accelerated methylation aging evinced more unpredictable temperaments and more psychological symptoms if their mothers reported more hostile parenting, but showed fewer difficulties if mothers engaged in less hostile parenting; children with lower levels of accelerated methylation age did not show associations between hostility and temperament or psychological symptoms. Effects were not accounted for by gestational age at birth, demographic factors, or the distribution of cell subtypes. These findings suggest that accelerated epigenetic age may function as a form of differential susceptibility, signaling increased risk for psychopathology in more aversive contexts but decreased risk in less aversive early environments. Taken together, they point to a novel biological process to consider within risk for psychopathology. En ligne : https://doi.org/10.1017/S0954579421000614 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

Consistency matters: Consistency in the timing and quality of daily interactions between parents and adolescents predicts production of proinflammatory cytokines in youths / Erika M. MANCZAK in Development and Psychopathology, 30-2 (May 2018)  

Public ISBD [article]  inDevelopment and Psychopathology > 30-2 (May 2018) . - p.373-382 Titre : Consistency matters: Consistency in the timing and quality of daily interactions between parents and adolescents predicts production of proinflammatory cytokines in youths Type de document : Texte imprimé et/ou numérique Auteurs : Erika M. MANCZAK, Auteur ; Adam K. K. LEIGH, Auteur ; Chia-Ping CHIN, Auteur ; Edith CHEN, Auteur Article en page(s) : p.373-382 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The current study examined whether consistency in day-to-day interactions between children and parents related to inflammatory cytokine production in youths. One hundred twenty-three parents recorded the daily quality of interactions and timing of leisure activities with their adolescent children for 2 weeks, and the degree of variability in those ratings was calculated. One year later, the production of proinflammatory cytokines in youths’ blood was measured in response to in vitro exposure to lipopolysaccharide (a bacterial product). The results indicate that greater variability in parent–child relationship quality related to greater stimulated proinflammatory cytokine production in youths, above and beyond overall relationship quality. Greater variability in the timing of parent–child leisure activities also predicted greater stimulated proinflammatory cytokine production in youths, regardless of the frequency of interactions. In sum, consistency in both the affective and temporal aspects of parent–child relationships may contribute to inflammatory processes in youth. En ligne : http://dx.doi.org/10.1017/S0954579417000918 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358 [article] Consistency matters: Consistency in the timing and quality of daily interactions between parents and adolescents predicts production of proinflammatory cytokines in youths [Texte imprimé et/ou numérique] / Erika M. MANCZAK, Auteur ; Adam K. K. LEIGH, Auteur ; Chia-Ping CHIN, Auteur ; Edith CHEN, Auteur . - p.373-382. Langues : Anglais (eng) in Development and Psychopathology > 30-2 (May 2018) . - p.373-382 Index. décimale : PER Périodiques Résumé : The current study examined whether consistency in day-to-day interactions between children and parents related to inflammatory cytokine production in youths. One hundred twenty-three parents recorded the daily quality of interactions and timing of leisure activities with their adolescent children for 2 weeks, and the degree of variability in those ratings was calculated. One year later, the production of proinflammatory cytokines in youths’ blood was measured in response to in vitro exposure to lipopolysaccharide (a bacterial product). The results indicate that greater variability in parent–child relationship quality related to greater stimulated proinflammatory cytokine production in youths, above and beyond overall relationship quality. Greater variability in the timing of parent–child leisure activities also predicted greater stimulated proinflammatory cytokine production in youths, regardless of the frequency of interactions. In sum, consistency in both the affective and temporal aspects of parent–child relationships may contribute to inflammatory processes in youth. En ligne : http://dx.doi.org/10.1017/S0954579417000918 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358

---

1 (1 - 2 / 2)