[article] 
inDevelopment and Psychopathology > 36-3 (August 2024) . - p.1239-1248

Titre :	Associations of the digit ratio with adolescent behavior problems are inconsistent with an intrauterine androgenic origin
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Allison L. SEELEY, Auteur ; Mercedes MORA-PLAZAS, Auteur ; Henry OLIVEROS, Auteur ; Constanza MARIN, Auteur ; Eduardo VILLAMOR, Auteur
Article en page(s) :	p.1239-1248
Langues :	Anglais (eng)
Mots-clés :	2D:4D  Adolescence  Digit ratio  Externalizing behavior  Internalizing behavior  Prenatal androgen exposure
Index. décimale :	PER Périodiques
Résumé :	A low second-to-fourth digit ratio (2D:4D) is a purported biomarker of increased intrauterine androgenic exposure, presumably linked to postnatal behavior. We aimed to examine the associations between 2D:4D and adolescence behavior problems expected from high (externalizing and attention problems) or low (internalizing problems) prenatal androgen exposure. We conducted a cross-sectional study of 1042 Colombian schoolchildren aged 11-18 y. We examined whether caliper-assessed 2D:4D was associated with behavior problems per the Youth Self-Report questionnaire. Mean problem standardized score point differences were estimated between hand- and sex-specific quintiles of 2D:4D with use of multivariable linear regression. Lower right-hand 2D:4D was associated with decreased externalizing and internalizing behavior problem scores. Corresponding lowest-to-median quintile adjusted mean differences (95% CI) were ?4.6 (?7.5, ?1.7) and ?3.5 (?6.4, ?0.6) points in boys; and ?3.4 (?5.9, ?0.9) and ?3.5 (?6.2, ?0.8) points in girls. Lower right-hand 2D:4D was also related to less attention and thought problems in boys, and to less social problems among girls. Associations were nonlinear, apparent only below 2D:4D medians, and stronger with the right than the left hand. In conclusion, right-hand 2D:4D is related to behavior problems in adolescence in directions that are not fully consistent with an androgenic exposure origin.
En ligne :	https://dx.doi.org/10.1017/S0954579423000470
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538

[article] Associations of the digit ratio with adolescent behavior problems are inconsistent with an intrauterine androgenic origin [Texte imprimé et/ou numérique] / Allison L. SEELEY, Auteur ; Mercedes MORA-PLAZAS, Auteur ; Henry OLIVEROS, Auteur ; Constanza MARIN, Auteur ; Eduardo VILLAMOR, Auteur . - p.1239-1248.
Langues : Anglais (eng)
in Development and Psychopathology > 36-3 (August 2024) . - p.1239-1248

Mots-clés :	2D:4D  Adolescence  Digit ratio  Externalizing behavior  Internalizing behavior  Prenatal androgen exposure
Index. décimale :	PER Périodiques
Résumé :	A low second-to-fourth digit ratio (2D:4D) is a purported biomarker of increased intrauterine androgenic exposure, presumably linked to postnatal behavior. We aimed to examine the associations between 2D:4D and adolescence behavior problems expected from high (externalizing and attention problems) or low (internalizing problems) prenatal androgen exposure. We conducted a cross-sectional study of 1042 Colombian schoolchildren aged 11-18 y. We examined whether caliper-assessed 2D:4D was associated with behavior problems per the Youth Self-Report questionnaire. Mean problem standardized score point differences were estimated between hand- and sex-specific quintiles of 2D:4D with use of multivariable linear regression. Lower right-hand 2D:4D was associated with decreased externalizing and internalizing behavior problem scores. Corresponding lowest-to-median quintile adjusted mean differences (95% CI) were ?4.6 (?7.5, ?1.7) and ?3.5 (?6.4, ?0.6) points in boys; and ?3.4 (?5.9, ?0.9) and ?3.5 (?6.2, ?0.8) points in girls. Lower right-hand 2D:4D was also related to less attention and thought problems in boys, and to less social problems among girls. Associations were nonlinear, apparent only below 2D:4D medians, and stronger with the right than the left hand. In conclusion, right-hand 2D:4D is related to behavior problems in adolescence in directions that are not fully consistent with an androgenic exposure origin.
En ligne :	https://dx.doi.org/10.1017/S0954579423000470
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538