Adaptation and Feasibility of the Mandarin Version of PEERS® for Autistic Adolescents / Yan LI ; Wuxia BAI ; Yu WANG ; Yongmei LI ; Yixiang XIE ; Xiaoqian HUANG ; Huilin ZHU ; Xiaobing ZOU in Journal of Autism and Developmental Disorders, 54-9 (September 2024)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 54-9 (September 2024) . - p.3387-3399 Titre : Adaptation and Feasibility of the Mandarin Version of PEERS® for Autistic Adolescents Type de document : texte imprimé Auteurs : Yan LI, Auteur ; Wuxia BAI, Auteur ; Yu WANG, Auteur ; Yongmei LI, Auteur ; Yixiang XIE, Auteur ; Xiaoqian HUANG, Auteur ; Huilin ZHU, Auteur ; Xiaobing ZOU, Auteur Article en page(s) : p.3387-3399 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Purpose: The Program for the Education and Enrichment of Relational Skills (PEERS®) is a group-based social skills training program for adolescents on the autism spectrum. Although the program has been shown to be effective in improving social skills in autistic adolescents, evidence of its effectiveness from the Mandarin-speaking Chinese population is sparse. The present study used a non-randomized, pre- and post-intervention research design to investigate the feasibility and cultural validity of the program, as well as examine the moderators of intervention outcomes. Methods: Thirty-three autistic adolescents with intelligence quotient above 70 (Mage = 13.57, SDage = 1.43; Male: Female 25:8) and their parents received 14 concurrent 90-minute sessions. Adolescents'autistic traits, challenging behaviors, emotional functioning, socio-cognitive process, social environment factors (school support), and caregivers'well-being were evaluated. Results: The findings suggest that with minor adjustments, the Mandarin version of PEERS® was generally acceptable and feasible for autistic adolescents and their parents. PEERS® may improve the social skills knowledge, reciprocal communication abilities, and emotional well-being of autistic adolescents. Also, participants with a higher level of school support, and parents with lower perceived subjective well-being at baseline may gain more benefits from PEERS®. The cultural adaptation and acceptability of the Mandarin Version of PEERS® were discussed. Conclusion: This feasibility study (Chinese Clinical Trial Registry: ChiCTR2200061417, 2022-06-23, retrospectively registered) provides a basis for further randomized control trials of the Mandarin version of PEERS®. En ligne : https://doi.org/10.1007/s10803-023-06056-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534 [article] Adaptation and Feasibility of the Mandarin Version of PEERS® for Autistic Adolescents [texte imprimé] / Yan LI, Auteur ; Wuxia BAI, Auteur ; Yu WANG, Auteur ; Yongmei LI, Auteur ; Yixiang XIE, Auteur ; Xiaoqian HUANG, Auteur ; Huilin ZHU, Auteur ; Xiaobing ZOU, Auteur . - p.3387-3399. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 54-9 (September 2024) . - p.3387-3399 Index. décimale : PER Périodiques Résumé : Purpose: The Program for the Education and Enrichment of Relational Skills (PEERS®) is a group-based social skills training program for adolescents on the autism spectrum. Although the program has been shown to be effective in improving social skills in autistic adolescents, evidence of its effectiveness from the Mandarin-speaking Chinese population is sparse. The present study used a non-randomized, pre- and post-intervention research design to investigate the feasibility and cultural validity of the program, as well as examine the moderators of intervention outcomes. Methods: Thirty-three autistic adolescents with intelligence quotient above 70 (Mage = 13.57, SDage = 1.43; Male: Female 25:8) and their parents received 14 concurrent 90-minute sessions. Adolescents'autistic traits, challenging behaviors, emotional functioning, socio-cognitive process, social environment factors (school support), and caregivers'well-being were evaluated. Results: The findings suggest that with minor adjustments, the Mandarin version of PEERS® was generally acceptable and feasible for autistic adolescents and their parents. PEERS® may improve the social skills knowledge, reciprocal communication abilities, and emotional well-being of autistic adolescents. Also, participants with a higher level of school support, and parents with lower perceived subjective well-being at baseline may gain more benefits from PEERS®. The cultural adaptation and acceptability of the Mandarin Version of PEERS® were discussed. Conclusion: This feasibility study (Chinese Clinical Trial Registry: ChiCTR2200061417, 2022-06-23, retrospectively registered) provides a basis for further randomized control trials of the Mandarin version of PEERS®. En ligne : https://doi.org/10.1007/s10803-023-06056-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=534

Association Between DCC Polymorphisms and Susceptibility to Autism Spectrum Disorder / Yan LI in Journal of Autism and Developmental Disorders, 50-10 (October 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3800-3809 Titre : Association Between DCC Polymorphisms and Susceptibility to Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Yan LI, Auteur ; Shuang QIU, Auteur ; Weijing ZHONG, Auteur ; Yong LI, Auteur ; Yunkai LIU, Auteur ; Yi CHENG, Auteur ; Yawen LIU, Auteur Article en page(s) : p.3800-3809 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Deleted in colorectal carcinoma gene  Haplotype analysis  Single nucleotide polymorphisms  Susceptibility Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) represents a group of childhood-onset lifelong neuro-developmental disorders. However, the association between single nucleotide polymorphisms (SNPs) in the deleted in colorectal carcinoma (DCC) gene and ASD susceptibility remains unclear. We investigated the association between ASD susceptibility and seven SNPs in DCC on the basis of a case-control study (231 ASD cases and 242 controls) in Chinese Han. We found that there was no association between ASD susceptibility and the seven SNPs in DCC; however, T-A haplotype (rs2229082-rs2270954), T-A-T-C haplotype (rs2229082-rs2270954-rs2292043-rs2292044), C-G-T-C-T haplotype (rs934345-rs17753970-rs2229082-rs2270954-rs2292043), C-G-T-C-T-G haplotype (rs934345-rs17753970-rs2229082-rs2270954-rs2292043-rs2292044), and G-G-T-C-C-C-C haplotype (rs934345-rs17753970-rs2229082-rs2270954-rs2292043-rs2292044-rs16956878) were associated with ASD susceptibility. Our results indicate that the haplotypes formed on the basis of the seven SNPs in DCC may be implicated in ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04417-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Association Between DCC Polymorphisms and Susceptibility to Autism Spectrum Disorder [texte imprimé] / Yan LI, Auteur ; Shuang QIU, Auteur ; Weijing ZHONG, Auteur ; Yong LI, Auteur ; Yunkai LIU, Auteur ; Yi CHENG, Auteur ; Yawen LIU, Auteur . - p.3800-3809. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-10 (October 2020) . - p.3800-3809 Mots-clés : Autism spectrum disorder  Deleted in colorectal carcinoma gene  Haplotype analysis  Single nucleotide polymorphisms  Susceptibility Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) represents a group of childhood-onset lifelong neuro-developmental disorders. However, the association between single nucleotide polymorphisms (SNPs) in the deleted in colorectal carcinoma (DCC) gene and ASD susceptibility remains unclear. We investigated the association between ASD susceptibility and seven SNPs in DCC on the basis of a case-control study (231 ASD cases and 242 controls) in Chinese Han. We found that there was no association between ASD susceptibility and the seven SNPs in DCC; however, T-A haplotype (rs2229082-rs2270954), T-A-T-C haplotype (rs2229082-rs2270954-rs2292043-rs2292044), C-G-T-C-T haplotype (rs934345-rs17753970-rs2229082-rs2270954-rs2292043), C-G-T-C-T-G haplotype (rs934345-rs17753970-rs2229082-rs2270954-rs2292043-rs2292044), and G-G-T-C-C-C-C haplotype (rs934345-rs17753970-rs2229082-rs2270954-rs2292043-rs2292044-rs16956878) were associated with ASD susceptibility. Our results indicate that the haplotypes formed on the basis of the seven SNPs in DCC may be implicated in ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04417-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Head circumference, body growth and development quotient in autism spectrum disorders are related in Chongqing, China / Hua WEI in Research in Autism Spectrum Disorders, 54 (October 2018)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 54 (October 2018) . - p.83-89 Titre : Head circumference, body growth and development quotient in autism spectrum disorders are related in Chongqing, China Type de document : texte imprimé Auteurs : Hua WEI, Auteur ; Qian CHENG, Auteur ; Qixia MEI, Auteur ; Xuan ZHANG, Auteur ; Li CHEN, Auteur ; Xiao LIU, Auteur ; Ying DAI, Auteur ; Ting YU, Auteur ; Yan LI, Auteur ; Yu ZHANG, Auteur ; Jie CHEN, Auteur ; Yongjie MIAO, Auteur ; Tingyu LI, Auteur Article en page(s) : p.83-89 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Head circumference  Body height  Body weight  Development quotient Index. décimale : PER Périodiques Résumé : Background It is unclear whether increased head circumference (HC) is actually an artifact of an overall overgrowth phenomenon or specific to the brain at all in autism spectrum disorders. This study compared the head circumferences, body weight and height of ASD children with a control group. We also discuss whether HC, body weight and height are correlated with development quotients in ASD children. Method We recruited 83 children with ASD (aged 2–5 years); they were gender and age matched to typically developing children in Chongqing (China) from 2013 to 2015. Their head circumference, body weight and height were collected. The ASD group was tested for the developmental quotient (DQ), which includes gross motor, fine motor, linguistic, personal-social and adaptive functioning. Results Our results showed that head circumference in the ASD group is significantly different from HC in the control group. The rate of macrocephaly was higher in the children with ASD compared with the control group. Some domains of DQ have statistically significant negative correlation with head circumference, weight and height. After adjusting for confounding factors, the fine motor was associated negatively with HC. Personal-social ability was associated negatively with weight. Gross motor was correlated negatively with the height. Conclusions Based on our results, we found significant HC differences in ASD group while lack of effect of either height or weight at the age of 2–5. HC, weight and height were separately negative correlated with some domains of development quotients. Further research is needed to understand the relationship between physical indicators and development level in autism. En ligne : https://doi.org/10.1016/j.rasd.2018.07.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Head circumference, body growth and development quotient in autism spectrum disorders are related in Chongqing, China [texte imprimé] / Hua WEI, Auteur ; Qian CHENG, Auteur ; Qixia MEI, Auteur ; Xuan ZHANG, Auteur ; Li CHEN, Auteur ; Xiao LIU, Auteur ; Ying DAI, Auteur ; Ting YU, Auteur ; Yan LI, Auteur ; Yu ZHANG, Auteur ; Jie CHEN, Auteur ; Yongjie MIAO, Auteur ; Tingyu LI, Auteur . - p.83-89. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 54 (October 2018) . - p.83-89 Mots-clés : Autism spectrum disorder  Head circumference  Body height  Body weight  Development quotient Index. décimale : PER Périodiques Résumé : Background It is unclear whether increased head circumference (HC) is actually an artifact of an overall overgrowth phenomenon or specific to the brain at all in autism spectrum disorders. This study compared the head circumferences, body weight and height of ASD children with a control group. We also discuss whether HC, body weight and height are correlated with development quotients in ASD children. Method We recruited 83 children with ASD (aged 2–5 years); they were gender and age matched to typically developing children in Chongqing (China) from 2013 to 2015. Their head circumference, body weight and height were collected. The ASD group was tested for the developmental quotient (DQ), which includes gross motor, fine motor, linguistic, personal-social and adaptive functioning. Results Our results showed that head circumference in the ASD group is significantly different from HC in the control group. The rate of macrocephaly was higher in the children with ASD compared with the control group. Some domains of DQ have statistically significant negative correlation with head circumference, weight and height. After adjusting for confounding factors, the fine motor was associated negatively with HC. Personal-social ability was associated negatively with weight. Gross motor was correlated negatively with the height. Conclusions Based on our results, we found significant HC differences in ASD group while lack of effect of either height or weight at the age of 2–5. HC, weight and height were separately negative correlated with some domains of development quotients. Further research is needed to understand the relationship between physical indicators and development level in autism. En ligne : https://doi.org/10.1016/j.rasd.2018.07.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms / Xiaoxin ZHAO in Journal of Autism and Developmental Disorders, 56-12 (December 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-12 (December 2026) . - p.4882-4891 Titre : Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms Type de document : texte imprimé Auteurs : Xiaoxin ZHAO, Auteur ; Shuyi ZHU, Auteur ; Yang CAO, Auteur ; Peipei CHENG, Auteur ; Yuxiong LIN, Auteur ; Tianyu ZHAI, Auteur ; Wenjie YAN, Auteur ; Yan LI, Auteur ; Wenqing JIANG, Auteur ; Wu HONG, Auteur ; Yasong DU, Auteur Article en page(s) : p.4882-4891 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The study aimed to investigate the alterations in spontaneous brain activity, as measured by fractional amplitude of low-frequency fluctuation (fALFF), in adolescents with high-functioning autism spectrum disorder (HFASD) and to explore the relationship between these alterations and the severity of autistic symptoms. We recruited 58 adolescents with HFASD and 66 typically developing (TD) controls, matched for age, gender, and full-scale intelligence quotient (FSIQ). Group-level analysis was conducted to identify variances in fALFF between individuals with autism spectrum disorder (ASD) and TD controls. The assessment of symptom severity in individuals with ASD was conducted utilizing the Autism Behavior Checklist (ABC). A voxel-wise correlation analysis was performed to investigate the relationships between symptom severity and the fALFF mapping in individuals with ASD, specifically in cerebral regions exhibiting ReHo abnormalities. Compared to TD controls, adolescents with HFASD showed reduced fALFF in several brain regions, including the bilateral inferior parietal lobule (IPL), right precuneus, right postcentral gyrus, bilateral middle temporal gyrus, and left cingulate gyrus. Positive correlations were observed between fALFF values in the left IPL and the Relating, Sensory, and total scores of the Autism Behavior Checklist (ABC) scale, while fALFF values in the left postcentral gyrus showed positive correlations with the Social self-help scores. These findings suggest that modifications in local spontaneous brain activity within these regions may be associated with the symptomatology of ASD, potentially enhancing our understanding of the neural mechanisms underlying the symptoms of ASD and facilitating earlier identification and improved treatment strategies. En ligne : https://doi.org/10.1007/s10803-025-06867-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=595 [article] Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms [texte imprimé] / Xiaoxin ZHAO, Auteur ; Shuyi ZHU, Auteur ; Yang CAO, Auteur ; Peipei CHENG, Auteur ; Yuxiong LIN, Auteur ; Tianyu ZHAI, Auteur ; Wenjie YAN, Auteur ; Yan LI, Auteur ; Wenqing JIANG, Auteur ; Wu HONG, Auteur ; Yasong DU, Auteur . - p.4882-4891. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-12 (December 2026) . - p.4882-4891 Index. décimale : PER Périodiques Résumé : The study aimed to investigate the alterations in spontaneous brain activity, as measured by fractional amplitude of low-frequency fluctuation (fALFF), in adolescents with high-functioning autism spectrum disorder (HFASD) and to explore the relationship between these alterations and the severity of autistic symptoms. We recruited 58 adolescents with HFASD and 66 typically developing (TD) controls, matched for age, gender, and full-scale intelligence quotient (FSIQ). Group-level analysis was conducted to identify variances in fALFF between individuals with autism spectrum disorder (ASD) and TD controls. The assessment of symptom severity in individuals with ASD was conducted utilizing the Autism Behavior Checklist (ABC). A voxel-wise correlation analysis was performed to investigate the relationships between symptom severity and the fALFF mapping in individuals with ASD, specifically in cerebral regions exhibiting ReHo abnormalities. Compared to TD controls, adolescents with HFASD showed reduced fALFF in several brain regions, including the bilateral inferior parietal lobule (IPL), right precuneus, right postcentral gyrus, bilateral middle temporal gyrus, and left cingulate gyrus. Positive correlations were observed between fALFF values in the left IPL and the Relating, Sensory, and total scores of the Autism Behavior Checklist (ABC) scale, while fALFF values in the left postcentral gyrus showed positive correlations with the Social self-help scores. These findings suggest that modifications in local spontaneous brain activity within these regions may be associated with the symptomatology of ASD, potentially enhancing our understanding of the neural mechanisms underlying the symptoms of ASD and facilitating earlier identification and improved treatment strategies. En ligne : https://doi.org/10.1007/s10803-025-06867-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=595

Mental disorders in childhood or adolescence and subsequent comprehensive school achievement / Yan LI in Journal of Child Psychology and Psychiatry, 67-11 (November 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-11 (November 2026) . - p.1796-1806 Titre : Mental disorders in childhood or adolescence and subsequent comprehensive school achievement Type de document : texte imprimé Auteurs : Yan LI, Auteur ; Ripsa NIEMI, Auteur ; Mai GUTVILIG, Auteur ; Marko ELOVAINIO, Auteur ; Marjo FLYKT, Auteur ; Christian HAKULINEN, Auteur Article en page(s) : p.1796-1806 Langues : Anglais (eng) Mots-clés : Mental disorders  school achievement  age at onset  gender  register-based data Index. décimale : PER Périodiques Résumé : Background Childhood mental disorders are associated with poorer school achievement, with potential negative long-term socio-economic consequences, but few large-scale studies have examined this association, particularly the role of age at onset. Using a nationwide Finnish cohort, we examined the associations between mental disorders and school achievement, focusing on gender and age at onset. Methods This nationwide cohort study used data from Finnish national registers. The study population consisted of all individuals born between January 1, 1990, and December 31, 2003, who completed their comprehensive education in Finland during the years 2005 to 2019 (n?=?837,546). The exposure was diagnosis of any mental disorder or specific mental disorders between the age of 1?year and graduation. School achievement was measured using the grade point average (GPA), a summative measure of performance across all subjects during the final three years of comprehensive school. Results Of the total study population (411,054 females, 426,492 males), 137,427 (16.41%) were diagnosed with a mental disorder before completing comprehensive school. Students with a mental disorder had lower school achievement compared with their peers without a diagnosis, ?0.41 [95% CI, ?0.41 to ?0.40]. The association was stronger for female students, ?0.45 [95% CI, ?0.46 to ?0.45], than for male students, ?0.37 [95% CI, ?0.38 to ?0.37]. Later-onset mental disorders were associated with poorer school achievement, a pattern observed across most specific mental disorders. Conclusions Childhood mental disorders are linked to lower school achievement, particularly among females and those diagnosed at a later age, underscoring the need for targeted psychological support for females and adolescents. En ligne : https://doi.org/10.1111/jcpp.70181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=594 [article] Mental disorders in childhood or adolescence and subsequent comprehensive school achievement [texte imprimé] / Yan LI, Auteur ; Ripsa NIEMI, Auteur ; Mai GUTVILIG, Auteur ; Marko ELOVAINIO, Auteur ; Marjo FLYKT, Auteur ; Christian HAKULINEN, Auteur . - p.1796-1806. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-11 (November 2026) . - p.1796-1806 Mots-clés : Mental disorders  school achievement  age at onset  gender  register-based data Index. décimale : PER Périodiques Résumé : Background Childhood mental disorders are associated with poorer school achievement, with potential negative long-term socio-economic consequences, but few large-scale studies have examined this association, particularly the role of age at onset. Using a nationwide Finnish cohort, we examined the associations between mental disorders and school achievement, focusing on gender and age at onset. Methods This nationwide cohort study used data from Finnish national registers. The study population consisted of all individuals born between January 1, 1990, and December 31, 2003, who completed their comprehensive education in Finland during the years 2005 to 2019 (n?=?837,546). The exposure was diagnosis of any mental disorder or specific mental disorders between the age of 1?year and graduation. School achievement was measured using the grade point average (GPA), a summative measure of performance across all subjects during the final three years of comprehensive school. Results Of the total study population (411,054 females, 426,492 males), 137,427 (16.41%) were diagnosed with a mental disorder before completing comprehensive school. Students with a mental disorder had lower school achievement compared with their peers without a diagnosis, ?0.41 [95% CI, ?0.41 to ?0.40]. The association was stronger for female students, ?0.45 [95% CI, ?0.46 to ?0.45], than for male students, ?0.37 [95% CI, ?0.38 to ?0.37]. Later-onset mental disorders were associated with poorer school achievement, a pattern observed across most specific mental disorders. Conclusions Childhood mental disorders are linked to lower school achievement, particularly among females and those diagnosed at a later age, underscoring the need for targeted psychological support for females and adolescents. En ligne : https://doi.org/10.1111/jcpp.70181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=594

Prenatal exposure to hypoxic risk conditions in autistic and neurotypical youth: Associated ventricular differences, sleep disturbance, and sensory processing / Cristian PRECIADO in Autism Research, 17-12 (December 2024)  

Permalink

Reply to Comment on "Association Between DCC Polymorphisms and Susceptibility to Autism Spectrum Disorder" / Yan LI in Journal of Autism and Developmental Disorders, 50-10 (October 2020)  

Permalink

rs1007893 and rs2070435 in DIP2A are associated with visual-reaction-behavior phenotype in Chinese Han population with autism spectrum disorder / Yan LI in Research in Autism Spectrum Disorders, 70 (February 2020)  

Permalink

Sexual and gender minority identity, peer victimization, and suicidality in adolescents: A mediation study using the ABCD Study / Sen LIU in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Permalink

---

1 (1 - 9 / 9) Par page : 25 50 100 200