Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study / Henrik DOBEWALL in Journal of Child Psychology and Psychiatry, 60-3 (March 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-3 (March 2019) . - p.277-285 Titre : Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study Type de document : texte imprimé Auteurs : Henrik DOBEWALL, Auteur ; Kateryna SAVELIEVA, Auteur ; I. SEPPALA, Auteur ; Ariel KNAFO-NOAM, Auteur ; Christian HAKULINEN, Auteur ; Marko ELOVAINIO, Auteur ; L. KELTIKANGAS-JARVINEN, Auteur ; L. PULKKI-RABACK, Auteur ; Olli T. RAITAKARI, Auteur ; T. LEHTIMAKI, Auteur ; Mirka HINTSANEN, Auteur Article en page(s) : p.277-285 Langues : Anglais (eng) Mots-clés : Gcta-greml  Parenting  child development  children's' genome-wide genotype variation  evocative gene-environment correlation  molecular genetics  temperament Index. décimale : PER Périodiques Résumé : BACKGROUND: Genomic analysis of the child might offer new potential to illuminate human parenting. We examined whether offspring (G2) genome-wide genotype variation (SNPs) is associated with their mother's (G1) emotional warmth and intolerance, indicating a gene-environment correlation. If this association is stronger than between G2's genes and their emotional warmth and intolerance toward their own children, then this would indicate the presence of an evocative gene-environment correlation. To further understand how G1 mother's parenting has been evoked by genetically influenced characteristics of the child (G2), we examined whether child (G2) temperament partially accounted for the association between offspring genes and parental responses. METHODS: Participants were from the Young Finns Study. G1 mothers (N = 2,349; mean age 39 years) self-reported the emotional warmth and intolerance toward G2 in 1980 when the participants were from 3 to 18 years old. G2 participants answered the same parenting scales in 2007/2012 (N = 1,378; mean age = 38 years in 2007; 59% female) when their children were on average 11 years old. Offspring temperament traits were self-reported in 1992 (G2 age range 15-30 years). Estimation of the phenotypic variance explained by the SNPs of G2 was done by genome-wide complex trait analysis with restricted maximum likelihood (GCTA-GREML). RESULTS: Results showed that the SNPs of a child (G2) explained 22.6% of the phenotypic variance of maternal intolerance (G1; p-value = .039). G2 temperament trait negative emotionality explained only 2.4% points of this association. G2 genes did not explain G1 emotional warmth or G2's own emotional warmth and intolerance. However, further analyses of a combined measure of both G1 parenting scales found genetic effects. Parent or child gender did not moderate the observed associations. CONCLUSIONS: Presented genome-wide evidence is pointing to the important role a child plays in affecting and shaping his/her family environment, though the underlying mechanisms remain unclear. En ligne : https://dx.doi.org/10.1111/jcpp.12995 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=385 [article] Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study [texte imprimé] / Henrik DOBEWALL, Auteur ; Kateryna SAVELIEVA, Auteur ; I. SEPPALA, Auteur ; Ariel KNAFO-NOAM, Auteur ; Christian HAKULINEN, Auteur ; Marko ELOVAINIO, Auteur ; L. KELTIKANGAS-JARVINEN, Auteur ; L. PULKKI-RABACK, Auteur ; Olli T. RAITAKARI, Auteur ; T. LEHTIMAKI, Auteur ; Mirka HINTSANEN, Auteur . - p.277-285. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-3 (March 2019) . - p.277-285 Mots-clés : Gcta-greml  Parenting  child development  children's' genome-wide genotype variation  evocative gene-environment correlation  molecular genetics  temperament Index. décimale : PER Périodiques Résumé : BACKGROUND: Genomic analysis of the child might offer new potential to illuminate human parenting. We examined whether offspring (G2) genome-wide genotype variation (SNPs) is associated with their mother's (G1) emotional warmth and intolerance, indicating a gene-environment correlation. If this association is stronger than between G2's genes and their emotional warmth and intolerance toward their own children, then this would indicate the presence of an evocative gene-environment correlation. To further understand how G1 mother's parenting has been evoked by genetically influenced characteristics of the child (G2), we examined whether child (G2) temperament partially accounted for the association between offspring genes and parental responses. METHODS: Participants were from the Young Finns Study. G1 mothers (N = 2,349; mean age 39 years) self-reported the emotional warmth and intolerance toward G2 in 1980 when the participants were from 3 to 18 years old. G2 participants answered the same parenting scales in 2007/2012 (N = 1,378; mean age = 38 years in 2007; 59% female) when their children were on average 11 years old. Offspring temperament traits were self-reported in 1992 (G2 age range 15-30 years). Estimation of the phenotypic variance explained by the SNPs of G2 was done by genome-wide complex trait analysis with restricted maximum likelihood (GCTA-GREML). RESULTS: Results showed that the SNPs of a child (G2) explained 22.6% of the phenotypic variance of maternal intolerance (G1; p-value = .039). G2 temperament trait negative emotionality explained only 2.4% points of this association. G2 genes did not explain G1 emotional warmth or G2's own emotional warmth and intolerance. However, further analyses of a combined measure of both G1 parenting scales found genetic effects. Parent or child gender did not moderate the observed associations. CONCLUSIONS: Presented genome-wide evidence is pointing to the important role a child plays in affecting and shaping his/her family environment, though the underlying mechanisms remain unclear. En ligne : https://dx.doi.org/10.1111/jcpp.12995 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=385

Mental disorders in childhood or adolescence and subsequent comprehensive school achievement / Yan LI in Journal of Child Psychology and Psychiatry, 67-11 (November 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-11 (November 2026) . - p.1796-1806 Titre : Mental disorders in childhood or adolescence and subsequent comprehensive school achievement Type de document : texte imprimé Auteurs : Yan LI, Auteur ; Ripsa NIEMI, Auteur ; Mai GUTVILIG, Auteur ; Marko ELOVAINIO, Auteur ; Marjo FLYKT, Auteur ; Christian HAKULINEN, Auteur Article en page(s) : p.1796-1806 Langues : Anglais (eng) Mots-clés : Mental disorders  school achievement  age at onset  gender  register-based data Index. décimale : PER Périodiques Résumé : Background Childhood mental disorders are associated with poorer school achievement, with potential negative long-term socio-economic consequences, but few large-scale studies have examined this association, particularly the role of age at onset. Using a nationwide Finnish cohort, we examined the associations between mental disorders and school achievement, focusing on gender and age at onset. Methods This nationwide cohort study used data from Finnish national registers. The study population consisted of all individuals born between January 1, 1990, and December 31, 2003, who completed their comprehensive education in Finland during the years 2005 to 2019 (n?=?837,546). The exposure was diagnosis of any mental disorder or specific mental disorders between the age of 1?year and graduation. School achievement was measured using the grade point average (GPA), a summative measure of performance across all subjects during the final three years of comprehensive school. Results Of the total study population (411,054 females, 426,492 males), 137,427 (16.41%) were diagnosed with a mental disorder before completing comprehensive school. Students with a mental disorder had lower school achievement compared with their peers without a diagnosis, ?0.41 [95% CI, ?0.41 to ?0.40]. The association was stronger for female students, ?0.45 [95% CI, ?0.46 to ?0.45], than for male students, ?0.37 [95% CI, ?0.38 to ?0.37]. Later-onset mental disorders were associated with poorer school achievement, a pattern observed across most specific mental disorders. Conclusions Childhood mental disorders are linked to lower school achievement, particularly among females and those diagnosed at a later age, underscoring the need for targeted psychological support for females and adolescents. En ligne : https://doi.org/10.1111/jcpp.70181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=594 [article] Mental disorders in childhood or adolescence and subsequent comprehensive school achievement [texte imprimé] / Yan LI, Auteur ; Ripsa NIEMI, Auteur ; Mai GUTVILIG, Auteur ; Marko ELOVAINIO, Auteur ; Marjo FLYKT, Auteur ; Christian HAKULINEN, Auteur . - p.1796-1806. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-11 (November 2026) . - p.1796-1806 Mots-clés : Mental disorders  school achievement  age at onset  gender  register-based data Index. décimale : PER Périodiques Résumé : Background Childhood mental disorders are associated with poorer school achievement, with potential negative long-term socio-economic consequences, but few large-scale studies have examined this association, particularly the role of age at onset. Using a nationwide Finnish cohort, we examined the associations between mental disorders and school achievement, focusing on gender and age at onset. Methods This nationwide cohort study used data from Finnish national registers. The study population consisted of all individuals born between January 1, 1990, and December 31, 2003, who completed their comprehensive education in Finland during the years 2005 to 2019 (n?=?837,546). The exposure was diagnosis of any mental disorder or specific mental disorders between the age of 1?year and graduation. School achievement was measured using the grade point average (GPA), a summative measure of performance across all subjects during the final three years of comprehensive school. Results Of the total study population (411,054 females, 426,492 males), 137,427 (16.41%) were diagnosed with a mental disorder before completing comprehensive school. Students with a mental disorder had lower school achievement compared with their peers without a diagnosis, ?0.41 [95% CI, ?0.41 to ?0.40]. The association was stronger for female students, ?0.45 [95% CI, ?0.46 to ?0.45], than for male students, ?0.37 [95% CI, ?0.38 to ?0.37]. Later-onset mental disorders were associated with poorer school achievement, a pattern observed across most specific mental disorders. Conclusions Childhood mental disorders are linked to lower school achievement, particularly among females and those diagnosed at a later age, underscoring the need for targeted psychological support for females and adolescents. En ligne : https://doi.org/10.1111/jcpp.70181 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=594

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