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Détail de l'auteur
Auteur K. J. PEALL |
Documents disponibles écrits par cet auteur (1)
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Using kinematic analyses to explore sensorimotor control impairments in children with 22q11.2 deletion syndrome / A. C. CUNNINGHAM in Journal of Neurodevelopmental Disorders, 11-1 (December 2019)
[article]
Titre : Using kinematic analyses to explore sensorimotor control impairments in children with 22q11.2 deletion syndrome Type de document : Texte imprimé et/ou numérique Auteurs : A. C. CUNNINGHAM, Auteur ; L. HILL, Auteur ; M. MON-WILLIAMS, Auteur ; K. J. PEALL, Auteur ; D. E. J. LINDEN, Auteur ; J. HALL, Auteur ; M. J. OWEN, Auteur ; M. B. M. VAN DEN BREE, Auteur Article en page(s) : 8 p. Langues : Anglais (eng) Mots-clés : 22q11.2 deletion syndrome Adhd Asd Anxiety Coordination Movement difficulties Index. décimale : PER Périodiques Résumé : BACKGROUND: The 22q11.2 deletion is associated with psychiatric and behavioural disorders, intellectual disability and multiple physical abnormalities. Recent research also indicates impaired coordination skills may be part of the clinical phenotype. This study aimed to characterise sensorimotor control abilities in children with 22q11.2 deletion syndrome (22q11.2DS) and investigate their relationships with co-occurring IQ impairments and psychopathology. METHODS: Fifty-four children with 22q11.2DS and 24 unaffected sibling controls, comparable in age and gender, underwent kinematic analysis of their hand movements, whilst performing a battery of three visuo-manual coordination tasks that measured their tracking, aiming and steering abilities. Additionally, standardised assessments of full-scale IQ (FSIQ), attention deficit hyperactivity disorder, indicative autism spectrum disorder (ASD) and anxiety disorder symptomatology were conducted. RESULTS: Children with 22q11.2DS showed deficits on seven of eight kinematic descriptors of movement quality across the three coordination tasks, compared to controls. Within 22q11.2DS cases, the extent of impairment on only three kinematic descriptors was significantly related to FSIQ after correction for multiple testing. Moreover, only error whilst visuo-manually tracking was nominally associated with ADHD symptom counts. CONCLUSIONS: Impairments in sensorimotor control are seen on a range of visuo-manual tasks in children with 22q11.2DS but the extent of these impairments are largely unrelated to the severity of other psychopathological and intellectual impairments commonly found in children with 22q11.2DS. En ligne : https://dx.doi.org/10.1186/s11689-019-9271-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409
in Journal of Neurodevelopmental Disorders > 11-1 (December 2019) . - 8 p.[article] Using kinematic analyses to explore sensorimotor control impairments in children with 22q11.2 deletion syndrome [Texte imprimé et/ou numérique] / A. C. CUNNINGHAM, Auteur ; L. HILL, Auteur ; M. MON-WILLIAMS, Auteur ; K. J. PEALL, Auteur ; D. E. J. LINDEN, Auteur ; J. HALL, Auteur ; M. J. OWEN, Auteur ; M. B. M. VAN DEN BREE, Auteur . - 8 p.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 11-1 (December 2019) . - 8 p.
Mots-clés : 22q11.2 deletion syndrome Adhd Asd Anxiety Coordination Movement difficulties Index. décimale : PER Périodiques Résumé : BACKGROUND: The 22q11.2 deletion is associated with psychiatric and behavioural disorders, intellectual disability and multiple physical abnormalities. Recent research also indicates impaired coordination skills may be part of the clinical phenotype. This study aimed to characterise sensorimotor control abilities in children with 22q11.2 deletion syndrome (22q11.2DS) and investigate their relationships with co-occurring IQ impairments and psychopathology. METHODS: Fifty-four children with 22q11.2DS and 24 unaffected sibling controls, comparable in age and gender, underwent kinematic analysis of their hand movements, whilst performing a battery of three visuo-manual coordination tasks that measured their tracking, aiming and steering abilities. Additionally, standardised assessments of full-scale IQ (FSIQ), attention deficit hyperactivity disorder, indicative autism spectrum disorder (ASD) and anxiety disorder symptomatology were conducted. RESULTS: Children with 22q11.2DS showed deficits on seven of eight kinematic descriptors of movement quality across the three coordination tasks, compared to controls. Within 22q11.2DS cases, the extent of impairment on only three kinematic descriptors was significantly related to FSIQ after correction for multiple testing. Moreover, only error whilst visuo-manually tracking was nominally associated with ADHD symptom counts. CONCLUSIONS: Impairments in sensorimotor control are seen on a range of visuo-manual tasks in children with 22q11.2DS but the extent of these impairments are largely unrelated to the severity of other psychopathological and intellectual impairments commonly found in children with 22q11.2DS. En ligne : https://dx.doi.org/10.1186/s11689-019-9271-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409