Acoustic properties of early vocalizations in infants with fragile X syndrome / Lisa R. HAMRICK in Autism Research, 12-11 (November 2019)  

Public ISBD [article]  inAutism Research > 12-11 (November 2019) . - p.1663-1679 Titre : Acoustic properties of early vocalizations in infants with fragile X syndrome Type de document : texte imprimé Auteurs : Lisa R. HAMRICK, Auteur ; Amanda SEIDL, Auteur ; Bridgette L. TONNSEN, Auteur Article en page(s) : p.1663-1679 Langues : Anglais (eng) Mots-clés : acoustics  autism spectrum disorder  canonical babbling  fragile X syndrome  pitch  vocalization duration  volubility Index. décimale : PER Périodiques Résumé : Fragile X syndrome (FXS) is a neurogenetic syndrome characterized by cognitive impairments and high rates of autism spectrum disorder (ASD). FXS is often highlighted as a model for exploring pathways of symptom expression in ASD due to the high prevalence of ASD symptoms in this population and the known single-gene cause of FXS. Early vocalization features-including volubility, complexity, duration, and pitch-have shown promise in detecting ASD in idiopathic ASD populations but have yet to be extensively studied in a population with a known genetic cause for ASD such as FXS. Investigating early trajectories of these features in FXS may inform our limited knowledge of potential mechanisms that predict later social communication outcomes. The present study addresses this need by presenting preliminary findings which (a) characterize early vocalization features in FXS relative to low-risk controls (LRC) and (b) test the specificity of associations between these features and language and ASD outcomes. We coded vocalization features during a standardized child-examiner interaction for 39 nine-month-olds (22 FXS, 17 LRC) whose clinical outcomes were assessed at 24 months. Our results provide preliminary evidence that within FXS, associations between vocalization features and 24-month language outcomes may diverge from those observed in LRC, and that vocalization features may be associated with later ASD symptoms. These findings provide a starting point for more research exploring these features as potential early markers of ASD in FXS, which in turn may lead to improved early identification methods, treatment approaches, and overall well-being of individuals with ASD. Autism Res2019. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Although vocal features of 9-month-olds with FXS did not differ from those of low-risk controls, several features were associated with later language and ASD outcomes at 24 months in FXS. These preliminary results suggest acoustic data may be related to clinical outcomes in FXS and potentially other high-risk populations. Further characterizing these associations may facilitate understanding of biological mechanisms and risk factors associated with social communication development and ASD. En ligne : http://dx.doi.org/10.1002/aur.2176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412 [article] Acoustic properties of early vocalizations in infants with fragile X syndrome [texte imprimé] / Lisa R. HAMRICK, Auteur ; Amanda SEIDL, Auteur ; Bridgette L. TONNSEN, Auteur . - p.1663-1679. Langues : Anglais (eng) in Autism Research > 12-11 (November 2019) . - p.1663-1679 Mots-clés : acoustics  autism spectrum disorder  canonical babbling  fragile X syndrome  pitch  vocalization duration  volubility Index. décimale : PER Périodiques Résumé : Fragile X syndrome (FXS) is a neurogenetic syndrome characterized by cognitive impairments and high rates of autism spectrum disorder (ASD). FXS is often highlighted as a model for exploring pathways of symptom expression in ASD due to the high prevalence of ASD symptoms in this population and the known single-gene cause of FXS. Early vocalization features-including volubility, complexity, duration, and pitch-have shown promise in detecting ASD in idiopathic ASD populations but have yet to be extensively studied in a population with a known genetic cause for ASD such as FXS. Investigating early trajectories of these features in FXS may inform our limited knowledge of potential mechanisms that predict later social communication outcomes. The present study addresses this need by presenting preliminary findings which (a) characterize early vocalization features in FXS relative to low-risk controls (LRC) and (b) test the specificity of associations between these features and language and ASD outcomes. We coded vocalization features during a standardized child-examiner interaction for 39 nine-month-olds (22 FXS, 17 LRC) whose clinical outcomes were assessed at 24 months. Our results provide preliminary evidence that within FXS, associations between vocalization features and 24-month language outcomes may diverge from those observed in LRC, and that vocalization features may be associated with later ASD symptoms. These findings provide a starting point for more research exploring these features as potential early markers of ASD in FXS, which in turn may lead to improved early identification methods, treatment approaches, and overall well-being of individuals with ASD. Autism Res2019. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Although vocal features of 9-month-olds with FXS did not differ from those of low-risk controls, several features were associated with later language and ASD outcomes at 24 months in FXS. These preliminary results suggest acoustic data may be related to clinical outcomes in FXS and potentially other high-risk populations. Further characterizing these associations may facilitate understanding of biological mechanisms and risk factors associated with social communication development and ASD. En ligne : http://dx.doi.org/10.1002/aur.2176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=412

Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2946-2955 Titre : Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur Article en page(s) : p.2946-2955 Langues : Anglais (eng) Mots-clés : Attentional disengagement  Autism  Infant siblings  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Atypical response to tactile input is associated with greater socio-communicative impairments in individuals with autism spectrum disorder (ASD). The current study examined overt orienting to caregiver-initiated touch in 12-month-olds at high risk for ASD (HRA) with (HRA+) and without (HRA-) a later diagnosis of ASD compared to low-risk comparison infants. Findings indicate that infants that go on to receive a diagnosis of ASD may more frequently fail to shift their attention in response to caregiver touch and when they do, they may be more likely to orient away from touch. Additionally, failure to respond to touch predicts ADOS severity scores at outcome suggesting that atypical response to touch may be an early indicator of autism severity. En ligne : http://dx.doi.org/10.1007/s10803-019-04021-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder [texte imprimé] / Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur . - p.2946-2955. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2946-2955 Mots-clés : Attentional disengagement  Autism  Infant siblings  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Atypical response to tactile input is associated with greater socio-communicative impairments in individuals with autism spectrum disorder (ASD). The current study examined overt orienting to caregiver-initiated touch in 12-month-olds at high risk for ASD (HRA) with (HRA+) and without (HRA-) a later diagnosis of ASD compared to low-risk comparison infants. Findings indicate that infants that go on to receive a diagnosis of ASD may more frequently fail to shift their attention in response to caregiver touch and when they do, they may be more likely to orient away from touch. Additionally, failure to respond to touch predicts ADOS severity scores at outcome suggesting that atypical response to touch may be an early indicator of autism severity. En ligne : http://dx.doi.org/10.1007/s10803-019-04021-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 50-3 (March 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.1064-1072 Titre : Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur Article en page(s) : p.1064-1072 Langues : Anglais (eng) Mots-clés : Autism  Infant siblings  Multimodal input  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Multimodal communication may facilitate attention in infants. This study examined the presentation of caregiver touch-only and touch + speech input to 12-month-olds at high (HRA) and low risk for ASD. Findings indicated that, although both groups received a greater number of touch + speech bouts compared to touch-only bouts, the duration of overall touch that overlapped with speech was significantly greater in the HRA group. Additionally, HRA infants were less responsive to touch-only bouts compared to touch + speech bouts suggesting that their mothers may use more touch + speech communication to elicit infant responses. Nonetheless, the exact role of touch in multimodal communication directed towards infants at high risk for ASD warrants further exploration. En ligne : http://dx.doi.org/10.1007/s10803-019-04310-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 [article] Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder [texte imprimé] / Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur . - p.1064-1072. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.1064-1072 Mots-clés : Autism  Infant siblings  Multimodal input  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Multimodal communication may facilitate attention in infants. This study examined the presentation of caregiver touch-only and touch + speech input to 12-month-olds at high (HRA) and low risk for ASD. Findings indicated that, although both groups received a greater number of touch + speech bouts compared to touch-only bouts, the duration of overall touch that overlapped with speech was significantly greater in the HRA group. Additionally, HRA infants were less responsive to touch-only bouts compared to touch + speech bouts suggesting that their mothers may use more touch + speech communication to elicit infant responses. Nonetheless, the exact role of touch in multimodal communication directed towards infants at high risk for ASD warrants further exploration. En ligne : http://dx.doi.org/10.1007/s10803-019-04310-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420

---

1 (1 - 3 / 3) Par page : 25 50 100 200