14 recherche sur le mot-clé 'Touch'

Touch and olfaction/taste differentiate children carrying a 16p11.2 deletion from children with ASD / Joana Maria Almeida OSORIO in Molecular Autism, 12 (2021)  

Public ISBD [article]  inMolecular Autism > 12 (2021) . - 8p. Titre : Touch and olfaction/taste differentiate children carrying a 16p11.2 deletion from children with ASD Type de document : Texte imprimé et/ou numérique Auteurs : Joana Maria Almeida OSORIO, Auteur ; Borja RODRIGUEZ-HERREROS, Auteur ; David ROMASCANO, Auteur ; Vincent JUNOD, Auteur ; Aline HABEGGER, Auteur ; Aurélie PAIN, Auteur ; Sonia RICHETIN, Auteur ; Paola YU, Auteur ; Bertrand ISIDOR, Auteur ; Lionel VAN MALDERGEM, Auteur ; Linda PONS, Auteur ; Sabine MANIFICAT, Auteur ; Nadia CHABANE, Auteur ; Marine JEQUIER GYGAX, Auteur ; Anne Manuela MAILLARD, Auteur Article en page(s) : 8p. Langues : Anglais (eng) Mots-clés : 16p11.2 deletion  Autism spectrum disorder (ASD)  Children  Copy number variants (CNV)  Olfaction  Sensory processing  Sensory processing measure (SPM)  Touch Index. décimale : PER Périodiques Résumé : BACKGROUND: Sensory processing atypicalities are frequent in Autism Spectrum Disorder (ASD) and neurodevelopmental disorders (NDD). Different domains of sensory processing appear to be differentially altered in these disorders. In this study, we explored the sensory profile of two clinical cohorts, in comparison with a sample of typically developing children. METHODS: Behavioral responses to sensory stimuli were assessed using the Sensory Processing Measure (parent-report questionnaire). We included 121 ASD children, 17 carriers of the 16p11.2 deletion (Del 16p11.2) and 45 typically developing (TD) children. All participants were aged between 2 and 12 years. Additional measures included the Tactile Defensiveness and Discrimination Test-Revised, Wechsler Intelligence Scales and Autism Diagnostic Observation Schedule (ADOS-2). Statistical analyses included MANCOVA and regression analyses. RESULTS: ASD children score significantly higher on all SPM subscales compared to TD. Del16p11.2 also scored higher than TD on all subscales except for tactile and olfactory/taste processing, in which they score similarly to TD. When assessing sensory modulation patterns (hyper-, hypo-responsiveness and seeking), ASD did not significantly differ from del16p11.2. Both groups had significantly higher scores across all patterns than the TD group. There was no significant association between the SPM Touch subscale and the TDDT-R. LIMITATIONS: Sensory processing was assessed using a parent-report questionnaire. Even though it captures observable behavior, a questionnaire does not assess sensory processing in all its complexity. The sample size of the genetic cohort and the small subset of ASD children with TDDT-R data render some of our results exploratory. Divergence between SPM Touch and TDDT-R raises important questions about the nature of the process that is assessed. CONCLUSIONS: Touch and olfaction/taste seem to be particularly affected in ASD children compared to del16p11.2. These results indicate that parent report measures can provide a useful perspective on behavioral expression. Sensory phenotyping, when combined with neurobiological and psychophysical methods, might have the potential to provide a better understanding of the sensory processing in ASD and in other NDD. En ligne : http://dx.doi.org/10.1186/s13229-020-00410-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442 [article] Touch and olfaction/taste differentiate children carrying a 16p11.2 deletion from children with ASD [Texte imprimé et/ou numérique] / Joana Maria Almeida OSORIO, Auteur ; Borja RODRIGUEZ-HERREROS, Auteur ; David ROMASCANO, Auteur ; Vincent JUNOD, Auteur ; Aline HABEGGER, Auteur ; Aurélie PAIN, Auteur ; Sonia RICHETIN, Auteur ; Paola YU, Auteur ; Bertrand ISIDOR, Auteur ; Lionel VAN MALDERGEM, Auteur ; Linda PONS, Auteur ; Sabine MANIFICAT, Auteur ; Nadia CHABANE, Auteur ; Marine JEQUIER GYGAX, Auteur ; Anne Manuela MAILLARD, Auteur . - 8p. Langues : Anglais (eng) in Molecular Autism > 12 (2021) . - 8p. Mots-clés : 16p11.2 deletion  Autism spectrum disorder (ASD)  Children  Copy number variants (CNV)  Olfaction  Sensory processing  Sensory processing measure (SPM)  Touch Index. décimale : PER Périodiques Résumé : BACKGROUND: Sensory processing atypicalities are frequent in Autism Spectrum Disorder (ASD) and neurodevelopmental disorders (NDD). Different domains of sensory processing appear to be differentially altered in these disorders. In this study, we explored the sensory profile of two clinical cohorts, in comparison with a sample of typically developing children. METHODS: Behavioral responses to sensory stimuli were assessed using the Sensory Processing Measure (parent-report questionnaire). We included 121 ASD children, 17 carriers of the 16p11.2 deletion (Del 16p11.2) and 45 typically developing (TD) children. All participants were aged between 2 and 12 years. Additional measures included the Tactile Defensiveness and Discrimination Test-Revised, Wechsler Intelligence Scales and Autism Diagnostic Observation Schedule (ADOS-2). Statistical analyses included MANCOVA and regression analyses. RESULTS: ASD children score significantly higher on all SPM subscales compared to TD. Del16p11.2 also scored higher than TD on all subscales except for tactile and olfactory/taste processing, in which they score similarly to TD. When assessing sensory modulation patterns (hyper-, hypo-responsiveness and seeking), ASD did not significantly differ from del16p11.2. Both groups had significantly higher scores across all patterns than the TD group. There was no significant association between the SPM Touch subscale and the TDDT-R. LIMITATIONS: Sensory processing was assessed using a parent-report questionnaire. Even though it captures observable behavior, a questionnaire does not assess sensory processing in all its complexity. The sample size of the genetic cohort and the small subset of ASD children with TDDT-R data render some of our results exploratory. Divergence between SPM Touch and TDDT-R raises important questions about the nature of the process that is assessed. CONCLUSIONS: Touch and olfaction/taste seem to be particularly affected in ASD children compared to del16p11.2. These results indicate that parent report measures can provide a useful perspective on behavioral expression. Sensory phenotyping, when combined with neurobiological and psychophysical methods, might have the potential to provide a better understanding of the sensory processing in ASD and in other NDD. En ligne : http://dx.doi.org/10.1186/s13229-020-00410-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=442

Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 49-7 (July 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2946-2955 Titre : Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Girija KADLASKAR, Auteur ; A. SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; C. A. NELSON, Auteur ; B. KEEHN, Auteur Article en page(s) : p.2946-2955 Langues : Anglais (eng) Mots-clés : Attentional disengagement  Autism  Infant siblings  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Atypical response to tactile input is associated with greater socio-communicative impairments in individuals with autism spectrum disorder (ASD). The current study examined overt orienting to caregiver-initiated touch in 12-month-olds at high risk for ASD (HRA) with (HRA+) and without (HRA-) a later diagnosis of ASD compared to low-risk comparison infants. Findings indicate that infants that go on to receive a diagnosis of ASD may more frequently fail to shift their attention in response to caregiver touch and when they do, they may be more likely to orient away from touch. Additionally, failure to respond to touch predicts ADOS severity scores at outcome suggesting that atypical response to touch may be an early indicator of autism severity. En ligne : http://dx.doi.org/10.1007/s10803-019-04021-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Atypical Response to Caregiver Touch in Infants at High Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Girija KADLASKAR, Auteur ; A. SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; C. A. NELSON, Auteur ; B. KEEHN, Auteur . - p.2946-2955. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-7 (July 2019) . - p.2946-2955 Mots-clés : Attentional disengagement  Autism  Infant siblings  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Atypical response to tactile input is associated with greater socio-communicative impairments in individuals with autism spectrum disorder (ASD). The current study examined overt orienting to caregiver-initiated touch in 12-month-olds at high risk for ASD (HRA) with (HRA+) and without (HRA-) a later diagnosis of ASD compared to low-risk comparison infants. Findings indicate that infants that go on to receive a diagnosis of ASD may more frequently fail to shift their attention in response to caregiver touch and when they do, they may be more likely to orient away from touch. Additionally, failure to respond to touch predicts ADOS severity scores at outcome suggesting that atypical response to touch may be an early indicator of autism severity. En ligne : http://dx.doi.org/10.1007/s10803-019-04021-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder / Girija KADLASKAR in Journal of Autism and Developmental Disorders, 50-3 (March 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.1064-1072 Titre : Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur Article en page(s) : p.1064-1072 Langues : Anglais (eng) Mots-clés : Autism  Infant siblings  Multimodal input  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Multimodal communication may facilitate attention in infants. This study examined the presentation of caregiver touch-only and touch + speech input to 12-month-olds at high (HRA) and low risk for ASD. Findings indicated that, although both groups received a greater number of touch + speech bouts compared to touch-only bouts, the duration of overall touch that overlapped with speech was significantly greater in the HRA group. Additionally, HRA infants were less responsive to touch-only bouts compared to touch + speech bouts suggesting that their mothers may use more touch + speech communication to elicit infant responses. Nonetheless, the exact role of touch in multimodal communication directed towards infants at high risk for ASD warrants further exploration. En ligne : http://dx.doi.org/10.1007/s10803-019-04310-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 [article] Caregiver Touch-Speech Communication and Infant Responses in 12-Month-Olds at High Risk for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Girija KADLASKAR, Auteur ; Amanda SEIDL, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Charles A. NELSON, Auteur ; Brandon KEEHN, Auteur . - p.1064-1072. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.1064-1072 Mots-clés : Autism  Infant siblings  Multimodal input  Social orienting  Touch Index. décimale : PER Périodiques Résumé : Multimodal communication may facilitate attention in infants. This study examined the presentation of caregiver touch-only and touch + speech input to 12-month-olds at high (HRA) and low risk for ASD. Findings indicated that, although both groups received a greater number of touch + speech bouts compared to touch-only bouts, the duration of overall touch that overlapped with speech was significantly greater in the HRA group. Additionally, HRA infants were less responsive to touch-only bouts compared to touch + speech bouts suggesting that their mothers may use more touch + speech communication to elicit infant responses. Nonetheless, the exact role of touch in multimodal communication directed towards infants at high risk for ASD warrants further exploration. En ligne : http://dx.doi.org/10.1007/s10803-019-04310-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420

Hyper-responsiveness to touch mediates social dysfunction in adults with autism spectrum disorders / Lars-Olov LUNDQVIST in Research in Autism Spectrum Disorders, 9 (January 2015)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 9 (January 2015) . - p.13-20 Titre : Hyper-responsiveness to touch mediates social dysfunction in adults with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Lars-Olov LUNDQVIST, Auteur Année de publication : 2015 Article en page(s) : p.13-20 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Touch  Tactile  Somatosensory  Sensory processing Index. décimale : PER Périodiques Résumé : Abstract This study investigated whether hyper-responsiveness to touch serves as a mediating variable that predicts social dysfunction in adults with autism spectrum disorders (ASD). Data were obtained from all adults with administratively defined intellectual disability in a region in Sweden (n = 915, where 143 had ASD). A multiple mediation modeling analysis revealed a well-fitted model (Satorra–Bentler scaled chi-square = 10.91, df = 7, p = 0.14, CFI = 0.99, RMSEA = 0.025), demonstrating that social dysfunction among adults with ASD was completely mediated by hyper-responsiveness to touch followed by impairment of speech and aggressive/destructive behavior. The results demonstrated that in adulthood, the tactile sensory system is foundational for social functioning in people with ASD, with diagnosis and intervention implications. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.09.012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 [article] Hyper-responsiveness to touch mediates social dysfunction in adults with autism spectrum disorders [Texte imprimé et/ou numérique] / Lars-Olov LUNDQVIST, Auteur . - 2015 . - p.13-20. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 9 (January 2015) . - p.13-20 Mots-clés : Autism spectrum disorders  Touch  Tactile  Somatosensory  Sensory processing Index. décimale : PER Périodiques Résumé : Abstract This study investigated whether hyper-responsiveness to touch serves as a mediating variable that predicts social dysfunction in adults with autism spectrum disorders (ASD). Data were obtained from all adults with administratively defined intellectual disability in a region in Sweden (n = 915, where 143 had ASD). A multiple mediation modeling analysis revealed a well-fitted model (Satorra–Bentler scaled chi-square = 10.91, df = 7, p = 0.14, CFI = 0.99, RMSEA = 0.025), demonstrating that social dysfunction among adults with ASD was completely mediated by hyper-responsiveness to touch followed by impairment of speech and aggressive/destructive behavior. The results demonstrated that in adulthood, the tactile sensory system is foundational for social functioning in people with ASD, with diagnosis and intervention implications. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.09.012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243

Self-reported Pleasantness Ratings and Examiner-Coded Defensiveness in Response to Touch in Children with ASD: Effects of Stimulus Material and Bodily Location / Carissa J. CASCIO in Journal of Autism and Developmental Disorders, 46-5 (May 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-5 (May 2016) . - p.1528-1537 Titre : Self-reported Pleasantness Ratings and Examiner-Coded Defensiveness in Response to Touch in Children with ASD: Effects of Stimulus Material and Bodily Location Type de document : Texte imprimé et/ou numérique Auteurs : Carissa J. CASCIO, Auteur ; Jill LORENZI, Auteur ; Grace T. BARANEK, Auteur Article en page(s) : p.1528-1537 Langues : Anglais (eng) Mots-clés : Touch  Tactile  Affective  Defensiveness  Pleasantness  Self-report Index. décimale : PER Périodiques Résumé : Tactile defensiveness, characterized by behavioral hyperresponsiveness and negative emotional responses to touch, is a common manifestation of aberrant sensory processing in autism spectrum disorders (ASD) and other developmental disabilities (DD). Variations in tactile defensiveness with the properties of the stimulus and the bodily site of stimulation have been addressed in adults with self-report of perceived tactile pleasantness, but not in children. We presented three materials (pleasant, unpleasant, social) at three bodily sites and measured both examiner-coded defensiveness and self-reported pleasantness from a group of children with ASD and two comparison groups (one with DD, one with typical development (TD)). The main findings were: (1) children with ASD and DD showed significantly more defensiveness reactions and lower pleasantness ratings than the TD group, with higher variability, (2) there was a double dissociation for the effects of material and bodily site of stimulation: while bodily site predicted behavioral defensiveness, material predicted pleasantness rating. Additionally, it was noted that (3) the most pleasant material and the social touch conditions best distinguished ASD and DD from TD on defensiveness, and (4) within the ASD group, social impairment and defensiveness in bodily sites associated with social touch were positively correlated, suggesting a clinically relevant distinction between social and discriminative touch in ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1961-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288 [article] Self-reported Pleasantness Ratings and Examiner-Coded Defensiveness in Response to Touch in Children with ASD: Effects of Stimulus Material and Bodily Location [Texte imprimé et/ou numérique] / Carissa J. CASCIO, Auteur ; Jill LORENZI, Auteur ; Grace T. BARANEK, Auteur . - p.1528-1537. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-5 (May 2016) . - p.1528-1537 Mots-clés : Touch  Tactile  Affective  Defensiveness  Pleasantness  Self-report Index. décimale : PER Périodiques Résumé : Tactile defensiveness, characterized by behavioral hyperresponsiveness and negative emotional responses to touch, is a common manifestation of aberrant sensory processing in autism spectrum disorders (ASD) and other developmental disabilities (DD). Variations in tactile defensiveness with the properties of the stimulus and the bodily site of stimulation have been addressed in adults with self-report of perceived tactile pleasantness, but not in children. We presented three materials (pleasant, unpleasant, social) at three bodily sites and measured both examiner-coded defensiveness and self-reported pleasantness from a group of children with ASD and two comparison groups (one with DD, one with typical development (TD)). The main findings were: (1) children with ASD and DD showed significantly more defensiveness reactions and lower pleasantness ratings than the TD group, with higher variability, (2) there was a double dissociation for the effects of material and bodily site of stimulation: while bodily site predicted behavioral defensiveness, material predicted pleasantness rating. Additionally, it was noted that (3) the most pleasant material and the social touch conditions best distinguished ASD and DD from TD on defensiveness, and (4) within the ASD group, social impairment and defensiveness in bodily sites associated with social touch were positively correlated, suggesting a clinically relevant distinction between social and discriminative touch in ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1961-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288

Caregiver?child proximity as a dimension of early experience / Whitney BARNETT in Development and Psychopathology, 34-2 (May 2022)  

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Functional Assays of Local Connectivity in the Somatosensory Cortex of Individuals with Autism / Mehmet Akif COSKUN in Autism Research, 6-3 (June 2013)  

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Perceptual and Neural Response to Affective Tactile Texture Stimulation in Adults with Autism Spectrum Disorders / Carissa J. CASCIO in Autism Research, 5-4 (August 2012)  

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Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism / L. A. SAPEY-TRIOMPHE in Autism Research, 12-4 (April 2019)  

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Visual and Proprioceptive Influences on Tactile Spatial Processing in Adults with Autism Spectrum Disorders / M. HENSE in Autism Research, 12-12 (December)  

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