Editorial Perspective: Issues for DSM 6 – an Alternative Model for Neurodevelopmental Disorders to enhance nosological validity and clinical utility / Michele POLETTI in Journal of Child Psychology and Psychiatry, 67-2 (February 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-2 (February 2026) . - p.305-308 Titre : Editorial Perspective: Issues for DSM 6 – an Alternative Model for Neurodevelopmental Disorders to enhance nosological validity and clinical utility Type de document : texte imprimé Auteurs : Michele POLETTI, Auteur ; Antonio PRETI, Auteur ; Andrea RABALLO, Auteur Article en page(s) : p.305-308 Langues : Anglais (eng) Mots-clés : Neurodevelopmental disorders  alternative dimensional model  severity levels  phenotypes  dimensional profiles. Index. décimale : PER Périodiques Résumé : The categorical diagnostic approach in the DSM-5 for Neurodevelopmental Disorders often reveals significant limitations, as high rates of comorbidity are common across conditions such as ADHD, autism spectrum disorder, and developmental coordination disorder. This co-occurrence aligns with a neuroconstructive dimensional perspective of neurodevelopment, which emphasizes the interconnectedness of cognitive, motor, and social impairments evolving throughout development. This perspective challenges modular and categorical views of neurodevelopmental phenotypic manifestations. Envisioning the DSM-6, a proposed dimensional Alternative Model for Neurodevelopmental Disorders (AMND) could integrate functioning severity and pathological traits, drawing inspiration from DSM-5 innovations, such as the Autism Spectrum Disorder severity levels. Such a model could facilitate nuanced profiling of individual strengths, needs, and developmental risks, accommodating both categorical and dimensional diagnostic approaches. This framework could also improve early identification of vulnerabilities to severe mental illnesses and clarify the developmental antecedents of adult-onset psychiatric conditions, offering pragmatic insights for clinical interventions and prognosis. En ligne : https://doi.org/10.1111/jcpp.70017 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=579 [article] Editorial Perspective: Issues for DSM 6 – an Alternative Model for Neurodevelopmental Disorders to enhance nosological validity and clinical utility [texte imprimé] / Michele POLETTI, Auteur ; Antonio PRETI, Auteur ; Andrea RABALLO, Auteur . - p.305-308. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-2 (February 2026) . - p.305-308 Mots-clés : Neurodevelopmental disorders  alternative dimensional model  severity levels  phenotypes  dimensional profiles. Index. décimale : PER Périodiques Résumé : The categorical diagnostic approach in the DSM-5 for Neurodevelopmental Disorders often reveals significant limitations, as high rates of comorbidity are common across conditions such as ADHD, autism spectrum disorder, and developmental coordination disorder. This co-occurrence aligns with a neuroconstructive dimensional perspective of neurodevelopment, which emphasizes the interconnectedness of cognitive, motor, and social impairments evolving throughout development. This perspective challenges modular and categorical views of neurodevelopmental phenotypic manifestations. Envisioning the DSM-6, a proposed dimensional Alternative Model for Neurodevelopmental Disorders (AMND) could integrate functioning severity and pathological traits, drawing inspiration from DSM-5 innovations, such as the Autism Spectrum Disorder severity levels. Such a model could facilitate nuanced profiling of individual strengths, needs, and developmental risks, accommodating both categorical and dimensional diagnostic approaches. This framework could also improve early identification of vulnerabilities to severe mental illnesses and clarify the developmental antecedents of adult-onset psychiatric conditions, offering pragmatic insights for clinical interventions and prognosis. En ligne : https://doi.org/10.1111/jcpp.70017 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=579

Editorial Perspective: Psychosis risk in adolescence - outcomes, comorbidity, and antipsychotics / Andrea RABALLO in Journal of Child Psychology and Psychiatry, 63-2 (February 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-2 (February 2022) . - p.241-244 Titre : Editorial Perspective: Psychosis risk in adolescence - outcomes, comorbidity, and antipsychotics Type de document : texte imprimé Auteurs : Andrea RABALLO, Auteur ; Michele POLETTI, Auteur ; Antonio PRETI, Auteur Article en page(s) : p.241-244 Langues : Anglais (eng) Mots-clés : Psychosis  adolescence  childhood  clinical high-risk state for psychosis  evidence  first-episode  prediction  prevention  psychosis risk  schizophrenia Index. décimale : PER Périodiques Résumé : Research on Clinical High-Risk for Psychosis (CHR-P) has led to a vigorous change in the field of early detection in psychiatry and is gradually expanding its focus toward early development. The Annual Research Review on psychosis risk in adolescents (Journal of Child Psychology and Psychiatry, 62, 2020 and 657) offers a wide-angle meta-analytical picture of such emerging trends in all areas relevant to CHR-P Research, that is, detection, prognosis, and intervention. This editorial perspective is meant to expand the clinical and conceptual reach of these meta-analytic findings in relation to (a) the influence of age on transition rate and scalability of the early detection model across the child-adolescent vs adult periods; (b) potential latent heterogeneity of the pathogenetic trajectories leading to CHR-P as suggested by comorbid psychopathologies; (c) controversial (or at least problematic) prognostic significance of antipsychotic exposure in CHR-P subjects, especially in children and adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Editorial Perspective: Psychosis risk in adolescence - outcomes, comorbidity, and antipsychotics [texte imprimé] / Andrea RABALLO, Auteur ; Michele POLETTI, Auteur ; Antonio PRETI, Auteur . - p.241-244. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-2 (February 2022) . - p.241-244 Mots-clés : Psychosis  adolescence  childhood  clinical high-risk state for psychosis  evidence  first-episode  prediction  prevention  psychosis risk  schizophrenia Index. décimale : PER Périodiques Résumé : Research on Clinical High-Risk for Psychosis (CHR-P) has led to a vigorous change in the field of early detection in psychiatry and is gradually expanding its focus toward early development. The Annual Research Review on psychosis risk in adolescents (Journal of Child Psychology and Psychiatry, 62, 2020 and 657) offers a wide-angle meta-analytical picture of such emerging trends in all areas relevant to CHR-P Research, that is, detection, prognosis, and intervention. This editorial perspective is meant to expand the clinical and conceptual reach of these meta-analytic findings in relation to (a) the influence of age on transition rate and scalability of the early detection model across the child-adolescent vs adult periods; (b) potential latent heterogeneity of the pathogenetic trajectories leading to CHR-P as suggested by comorbid psychopathologies; (c) controversial (or at least problematic) prognostic significance of antipsychotic exposure in CHR-P subjects, especially in children and adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13438 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

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