Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1 / Gorana POBRIC in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1478-1494 Titre : Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1 Type de document : texte imprimé Auteurs : Gorana POBRIC, Auteur ; Jason R. TAYLOR, Auteur ; Hemavathy M. RAMALINGAM, Auteur ; Emily PYE, Auteur ; Louise ROBINSON, Auteur ; Grace VASSALLO, Auteur ; JeYoung JUNG, Auteur ; Misty BHANDARY, Auteur ; Karolina SZUMANSKA-RYT, Auteur ; Louise THEODOSIOU, Auteur ; D. Gareth EVANS, Auteur ; Judith EELLOO, Auteur ; Emma BURKITT-WRIGHT, Auteur ; Johan HULLEMAN, Auteur ; Jonathan GREEN, Auteur ; Shruti GARG, Auteur Article en page(s) : p.1478-1494 Langues : Anglais (eng) Mots-clés : Adolescent  Autism Spectrum Disorder  Cognition  Evoked Potentials/physiology  Humans  Memory, Short-Term/physiology  Neurofibromatosis 1/complications  Eeg  N-back task  Neurofibromatosis 1  P300  Working memory Index. décimale : PER Périodiques Résumé : Neurofibromatosis 1 (NF1) is a single gene disorder associated with working Memory (WM) impairments. The aim of this study was to investigate P300 event-related potential (ERP) associated with WM in NF1. Sixteen adolescents with NF1 were compared with controls on measures of WM and EEG was recorded during a WM nback task. The NF1 group showed poorer performance on measures of WM as compared to the control group. No group differences were observed in P300 amplitude at Pz, but P300 latency was shorter in the NF1 group. Topographic analyses of P300 amplitude showed group differences indicating neural processing differences in the NF1 group relative to controls, which possibly contribute to the cognitive deficits seen in this population. En ligne : http://dx.doi.org/10.1007/s10803-021-05043-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] Cognitive and Electrophysiological Correlates of Working Memory Impairments in Neurofibromatosis Type 1 [texte imprimé] / Gorana POBRIC, Auteur ; Jason R. TAYLOR, Auteur ; Hemavathy M. RAMALINGAM, Auteur ; Emily PYE, Auteur ; Louise ROBINSON, Auteur ; Grace VASSALLO, Auteur ; JeYoung JUNG, Auteur ; Misty BHANDARY, Auteur ; Karolina SZUMANSKA-RYT, Auteur ; Louise THEODOSIOU, Auteur ; D. Gareth EVANS, Auteur ; Judith EELLOO, Auteur ; Emma BURKITT-WRIGHT, Auteur ; Johan HULLEMAN, Auteur ; Jonathan GREEN, Auteur ; Shruti GARG, Auteur . - p.1478-1494. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1478-1494 Mots-clés : Adolescent  Autism Spectrum Disorder  Cognition  Evoked Potentials/physiology  Humans  Memory, Short-Term/physiology  Neurofibromatosis 1/complications  Eeg  N-back task  Neurofibromatosis 1  P300  Working memory Index. décimale : PER Périodiques Résumé : Neurofibromatosis 1 (NF1) is a single gene disorder associated with working Memory (WM) impairments. The aim of this study was to investigate P300 event-related potential (ERP) associated with WM in NF1. Sixteen adolescents with NF1 were compared with controls on measures of WM and EEG was recorded during a WM nback task. The NF1 group showed poorer performance on measures of WM as compared to the control group. No group differences were observed in P300 amplitude at Pz, but P300 latency was shorter in the NF1 group. Topographic analyses of P300 amplitude showed group differences indicating neural processing differences in the NF1 group relative to controls, which possibly contribute to the cognitive deficits seen in this population. En ligne : http://dx.doi.org/10.1007/s10803-021-05043-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

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