Are flatter diurnal cortisol rhythms associated with major depression and anxiety disorders in late adolescence? The role of life stress and daily negative emotion / Leah D. DOANE in Development and Psychopathology, 25-3 (August 2013)  

Public ISBD [article]  inDevelopment and Psychopathology > 25-3 (August 2013) . - p.629-642 Titre : Are flatter diurnal cortisol rhythms associated with major depression and anxiety disorders in late adolescence? The role of life stress and daily negative emotion Type de document : Texte imprimé et/ou numérique Auteurs : Leah D. DOANE, Auteur ; Susan MINEKA, Auteur ; Richard E. ZINBARG, Auteur ; Michelle G. CRASKE, Auteur ; James W. GRIFFITH, Auteur ; Emma K. ADAM, Auteur Article en page(s) : p.629-642 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Alterations in hypothalamic–pituitary–adrenal (HPA) axis functioning have been associated with major depression disorder (MDD) and some anxiety disorders. Few researchers have tested the possibility that high levels of recent life stress or elevations in negative emotion may partially account for the HPA axis alterations observed in these disorders. In a sample of 300 adolescents from the Youth Emotion Project, we examined associations between MDD and anxiety disorders, dimensional measures of internalizing symptomatology, life stress, mood on the days of cortisol testing, and HPA axis functioning. Adolescents with a past MDD episode and those with a recent MDD episode comorbid with an anxiety disorder had flatter diurnal cortisol slopes than adolescents without a history of internalizing disorders. Higher reports of general distress, a dimension of internalizing symptomatology, were also associated with flatter slopes. Negative emotion, specifically sadness and loneliness, was associated with flatter slopes and partially accounted for the associations between comorbid MDD and anxiety disorders and cortisol. The associations between past MDD and cortisol slopes were not accounted for by negative emotion, dimensional variation in internalizing symptomatology, or levels of life stress, indicating that flatter cortisol slopes may also be a “scar” marker of past experiences of MDD. En ligne : http://dx.doi.org/10.1017/S0954579413000060 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210 [article] Are flatter diurnal cortisol rhythms associated with major depression and anxiety disorders in late adolescence? The role of life stress and daily negative emotion [Texte imprimé et/ou numérique] / Leah D. DOANE, Auteur ; Susan MINEKA, Auteur ; Richard E. ZINBARG, Auteur ; Michelle G. CRASKE, Auteur ; James W. GRIFFITH, Auteur ; Emma K. ADAM, Auteur . - p.629-642. Langues : Anglais (eng) in Development and Psychopathology > 25-3 (August 2013) . - p.629-642 Index. décimale : PER Périodiques Résumé : Alterations in hypothalamic–pituitary–adrenal (HPA) axis functioning have been associated with major depression disorder (MDD) and some anxiety disorders. Few researchers have tested the possibility that high levels of recent life stress or elevations in negative emotion may partially account for the HPA axis alterations observed in these disorders. In a sample of 300 adolescents from the Youth Emotion Project, we examined associations between MDD and anxiety disorders, dimensional measures of internalizing symptomatology, life stress, mood on the days of cortisol testing, and HPA axis functioning. Adolescents with a past MDD episode and those with a recent MDD episode comorbid with an anxiety disorder had flatter diurnal cortisol slopes than adolescents without a history of internalizing disorders. Higher reports of general distress, a dimension of internalizing symptomatology, were also associated with flatter slopes. Negative emotion, specifically sadness and loneliness, was associated with flatter slopes and partially accounted for the associations between comorbid MDD and anxiety disorders and cortisol. The associations between past MDD and cortisol slopes were not accounted for by negative emotion, dimensional variation in internalizing symptomatology, or levels of life stress, indicating that flatter cortisol slopes may also be a “scar” marker of past experiences of MDD. En ligne : http://dx.doi.org/10.1017/S0954579413000060 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=210

Early-life adversity and risk for depression and anxiety: The role of interpersonal support / Allison V. METTS in Development and Psychopathology, 35-2 (May 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-2 (May 2023) . - p.863-875 Titre : Early-life adversity and risk for depression and anxiety: The role of interpersonal support Type de document : Texte imprimé et/ou numérique Auteurs : Allison V. METTS, Auteur ; Julia S. YARRINGTON, Auteur ; Richard ZINBARG, Auteur ; Constance HAMMEN, Auteur ; Susan MINEKA, Auteur ; Craig ENDERS, Auteur ; Michelle G. CRASKE, Auteur Article en page(s) : p.863-875 Langues : Anglais (eng) Mots-clés : anxiety  depression  early-life adversity  general benefits  interpersonal support Index. décimale : PER Périodiques Résumé : Early-life adversity is a major risk factor for psychopathology, but not all who experience adversity develop psychopathology. The current study evaluated whether the links between child and adolescent adversity and depression and anxiety were described by general benefits and/or buffering effects of interpersonal support. Data from 456 adolescents oversampled on neuroticism over a 5-year period were examined in a series of discrete-time survival analyses to predict subsequent disorder onsets. Models examined linear, quadratic, and interactive effects of interpersonal support over time, as measured by chronic interpersonal stress interview ratings. Results did not support buffering effects of interpersonal support against either child or adolescent adversity in predicting depression or anxiety. However, there was support for the general benefits model of interpersonal support as evidenced by follow-up analyses of significant quadratic effects of interpersonal support, demonstrating that higher interpersonal support led to decreased likelihood of depression and anxiety onsets. Secondary analyses demonstrated that effects of interpersonal support remained after accounting for baseline depression and anxiety diagnoses. Further, quadratic effects were driven by social domains as opposed to familial domains when considering child adversity. Implications for interventions and randomized controlled prevention trials regarding interpersonal relationships are discussed. En ligne : http://dx.doi.org/10.1017/S0954579422000116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504 [article] Early-life adversity and risk for depression and anxiety: The role of interpersonal support [Texte imprimé et/ou numérique] / Allison V. METTS, Auteur ; Julia S. YARRINGTON, Auteur ; Richard ZINBARG, Auteur ; Constance HAMMEN, Auteur ; Susan MINEKA, Auteur ; Craig ENDERS, Auteur ; Michelle G. CRASKE, Auteur . - p.863-875. Langues : Anglais (eng) in Development and Psychopathology > 35-2 (May 2023) . - p.863-875 Mots-clés : anxiety  depression  early-life adversity  general benefits  interpersonal support Index. décimale : PER Périodiques Résumé : Early-life adversity is a major risk factor for psychopathology, but not all who experience adversity develop psychopathology. The current study evaluated whether the links between child and adolescent adversity and depression and anxiety were described by general benefits and/or buffering effects of interpersonal support. Data from 456 adolescents oversampled on neuroticism over a 5-year period were examined in a series of discrete-time survival analyses to predict subsequent disorder onsets. Models examined linear, quadratic, and interactive effects of interpersonal support over time, as measured by chronic interpersonal stress interview ratings. Results did not support buffering effects of interpersonal support against either child or adolescent adversity in predicting depression or anxiety. However, there was support for the general benefits model of interpersonal support as evidenced by follow-up analyses of significant quadratic effects of interpersonal support, demonstrating that higher interpersonal support led to decreased likelihood of depression and anxiety onsets. Secondary analyses demonstrated that effects of interpersonal support remained after accounting for baseline depression and anxiety diagnoses. Further, quadratic effects were driven by social domains as opposed to familial domains when considering child adversity. Implications for interventions and randomized controlled prevention trials regarding interpersonal relationships are discussed. En ligne : http://dx.doi.org/10.1017/S0954579422000116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504

Experiences of adversity in childhood and adolescence and cortisol in late adolescence / Courtenay L. KESSLER in Development and Psychopathology, 35-3 (August 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-3 (August 2023) . - p.1235-1250 Titre : Experiences of adversity in childhood and adolescence and cortisol in late adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Courtenay L. KESSLER, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur ; Susan MINEKA, Auteur ; Richard E. ZINBARG, Auteur ; Michelle CRASKE, Auteur ; Emma K. ADAM, Auteur Article en page(s) : p.1235-1250 Langues : Anglais (eng) Mots-clés : cortisol  diurnal rhythm  early adversity  HPA axis Index. décimale : PER Périodiques Résumé : Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of different characteristics of adversity remains unknown. In this study, we examine how developmental timing (childhood vs. adolescence), severity (major vs. minor), and domain of early life adversity relate to diurnal cortisol rhythms in late adolescence. We assessed adversity retrospectively in early adulthood in a subsample of 236 participants from a longitudinal study of a diverse community sample of suburban adolescents oversampled for high neuroticism. We used multilevel modeling to assess associations between our adversity measures and the diurnal cortisol rhythm (waking and bedtime cortisol, awakening response, slope, and average cortisol). Major childhood adversities were associated with flatter daily slope, and minor adolescent adversities were associated with greater average daily cortisol. Examining domains of childhood adversities, major neglect and sexual abuse were associated with flatter slope and lower waking cortisol, with sexual abuse also associated with higher cortisol awakening response. Major physical abuse was associated with higher waking cortisol. Among adolescent adversities domains, minor neglect, emotional abuse, and witnessing violence were associated with greater average cortisol. These results suggest severity, developmental timing, and domain of adversity influence the association of early life adversity with stress response system functioning. En ligne : http://dx.doi.org/10.1017/S0954579421001152 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510 [article] Experiences of adversity in childhood and adolescence and cortisol in late adolescence [Texte imprimé et/ou numérique] / Courtenay L. KESSLER, Auteur ; Suzanne VRSHEK-SCHALLHORN, Auteur ; Susan MINEKA, Auteur ; Richard E. ZINBARG, Auteur ; Michelle CRASKE, Auteur ; Emma K. ADAM, Auteur . - p.1235-1250. Langues : Anglais (eng) in Development and Psychopathology > 35-3 (August 2023) . - p.1235-1250 Mots-clés : cortisol  diurnal rhythm  early adversity  HPA axis Index. décimale : PER Périodiques Résumé : Early life adversity influences the diurnal cortisol rhythm, yet the relative influence of different characteristics of adversity remains unknown. In this study, we examine how developmental timing (childhood vs. adolescence), severity (major vs. minor), and domain of early life adversity relate to diurnal cortisol rhythms in late adolescence. We assessed adversity retrospectively in early adulthood in a subsample of 236 participants from a longitudinal study of a diverse community sample of suburban adolescents oversampled for high neuroticism. We used multilevel modeling to assess associations between our adversity measures and the diurnal cortisol rhythm (waking and bedtime cortisol, awakening response, slope, and average cortisol). Major childhood adversities were associated with flatter daily slope, and minor adolescent adversities were associated with greater average daily cortisol. Examining domains of childhood adversities, major neglect and sexual abuse were associated with flatter slope and lower waking cortisol, with sexual abuse also associated with higher cortisol awakening response. Major physical abuse was associated with higher waking cortisol. Among adolescent adversities domains, minor neglect, emotional abuse, and witnessing violence were associated with greater average cortisol. These results suggest severity, developmental timing, and domain of adversity influence the association of early life adversity with stress response system functioning. En ligne : http://dx.doi.org/10.1017/S0954579421001152 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=510

Incorporating hypothalamic–pituitary–adrenal axis measures into preventive interventions for adolescent depression: Are we there yet? / Emma K. ADAM in Development and Psychopathology, 20-3 (Summer 2008)  

Public ISBD [article]  inDevelopment and Psychopathology > 20-3 (Summer 2008) . - p.975-1001 Titre : Incorporating hypothalamic–pituitary–adrenal axis measures into preventive interventions for adolescent depression: Are we there yet? Type de document : Texte imprimé et/ou numérique Auteurs : Emma K. ADAM, Auteur ; Jonathan M. SUTTON, Auteur ; Leah D. DOANE, Auteur ; Susan MINEKA, Auteur Année de publication : 2008 Article en page(s) : p.975-1001 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Altered functioning of the hypothalamic–pituitary–adrenal (HPA) axis is a robust correlate of major depression in adults, and to a lesser extent, in adolescents. Premorbid differences in HPA axis function have been found to prospectively predict the onset of adolescent depression. To what extent might our knowledge of HPA axis function in adolescents with, or at risk for, depression, help guide efforts to prevent depression in this age group? We review evidence regarding the role of the HPA axis in the development of adolescent depression, and examine whether and which HPA axis measures might be useful in guiding prevention efforts as (a) as a criterion by which to select youth at risk for depression, (b) as a predictor of which youth will be most responsive to prevention efforts, and (c) as an indicator of whether prevention/intervention efforts are working. We conclude that our current understanding of the HPA axis, and its measurement, in adolescent depression are not sufficiently precise to be of immediate practical use in improving prevention efforts. Incorporating HPA axis measures into prevention studies, however, would be immensely useful in clarifying the role of the HPA axis in adolescent depression, such that future prevention efforts might more confidently rely on HPA axis information. En ligne : http://dx.doi.org/10.1017/s0954579408000461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544 [article] Incorporating hypothalamic–pituitary–adrenal axis measures into preventive interventions for adolescent depression: Are we there yet? [Texte imprimé et/ou numérique] / Emma K. ADAM, Auteur ; Jonathan M. SUTTON, Auteur ; Leah D. DOANE, Auteur ; Susan MINEKA, Auteur . - 2008 . - p.975-1001. Langues : Anglais (eng) in Development and Psychopathology > 20-3 (Summer 2008) . - p.975-1001 Index. décimale : PER Périodiques Résumé : Altered functioning of the hypothalamic–pituitary–adrenal (HPA) axis is a robust correlate of major depression in adults, and to a lesser extent, in adolescents. Premorbid differences in HPA axis function have been found to prospectively predict the onset of adolescent depression. To what extent might our knowledge of HPA axis function in adolescents with, or at risk for, depression, help guide efforts to prevent depression in this age group? We review evidence regarding the role of the HPA axis in the development of adolescent depression, and examine whether and which HPA axis measures might be useful in guiding prevention efforts as (a) as a criterion by which to select youth at risk for depression, (b) as a predictor of which youth will be most responsive to prevention efforts, and (c) as an indicator of whether prevention/intervention efforts are working. We conclude that our current understanding of the HPA axis, and its measurement, in adolescent depression are not sufficiently precise to be of immediate practical use in improving prevention efforts. Incorporating HPA axis measures into prevention studies, however, would be immensely useful in clarifying the role of the HPA axis in adolescent depression, such that future prevention efforts might more confidently rely on HPA axis information. En ligne : http://dx.doi.org/10.1017/s0954579408000461 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=544

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