60 recherche sur le mot-clé 'cortisol'

Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play / Clayton W. SCHUPP in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2405-2417 Titre : Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play Type de document : Texte imprimé et/ou numérique Auteurs : Clayton W. SCHUPP, Auteur ; David SIMON, Auteur ; Blythe A. CORBETT, Auteur Article en page(s) : p.2405-2417 Langues : Anglais (eng) Mots-clés : Autism  Cortisol  Play  Social  Stress  Responder Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) demonstrate significant heterogeneity in their profiles of social interaction and stress responsivity. We evaluated behavior and stress response in 52 male children ages 8–12 in a naturalistic playground interaction paradigm involving a child with ASD, a typically developing peer, and a same-age confederate. Younger children in the ASD group engaged in 5.8 times more approach behavior and showed a lower cortisol response than their older peers. Those that verbally initiated with their peers also showed a higher cortisol response. Older children with ASD exhibited the highest stress responsivity, while younger children with ASD showed more willingness to approach others without apparent stress. Intervening early and often may contribute to improvements in social engagement in youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1790-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Cortisol Responsivity Differences in Children with Autism Spectrum Disorders During Free and Cooperative Play [Texte imprimé et/ou numérique] / Clayton W. SCHUPP, Auteur ; David SIMON, Auteur ; Blythe A. CORBETT, Auteur . - p.2405-2417. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2405-2417 Mots-clés : Autism  Cortisol  Play  Social  Stress  Responder Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) demonstrate significant heterogeneity in their profiles of social interaction and stress responsivity. We evaluated behavior and stress response in 52 male children ages 8–12 in a naturalistic playground interaction paradigm involving a child with ASD, a typically developing peer, and a same-age confederate. Younger children in the ASD group engaged in 5.8 times more approach behavior and showed a lower cortisol response than their older peers. Those that verbally initiated with their peers also showed a higher cortisol response. Older children with ASD exhibited the highest stress responsivity, while younger children with ASD showed more willingness to approach others without apparent stress. Intervening early and often may contribute to improvements in social engagement in youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-013-1790-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Emotional stress, cortisol response, and cortisol rhythm in autism spectrum disorders: A systematic review / Kim VAN DER LINDEN in Research in Autism Spectrum Disorders, 98 (October 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 98 (October 2022) . - 102039 Titre : Emotional stress, cortisol response, and cortisol rhythm in autism spectrum disorders: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Kim VAN DER LINDEN, Auteur ; Claudia SIMONS, Auteur ; Thérèse VAN AMELSVOORT, Auteur ; Machteld MARCELIS, Auteur Article en page(s) : 102039 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Stress  Cortisol  Cortisol awakening response Index. décimale : PER Périodiques Résumé : Background This systematic review evaluated whether there is evidence for (i) increased emotional stress levels, and (ii) a different biological stress response or rhythm [i.e., cortisol stress response, diurnal rhythm, or cortisol awakening response (CAR)] in individuals with autism spectrum disorder (ASD) relative to controls. Thirdly, the evidence for an association between emotional and biological stress in ASD was reviewed. Method MEDLINE, Cochrane Library, and SAGE journals were searched until December 2020. In this review, there were no limitations regarding age, sex, or intelligence quotient. Studies were only reviewed if results were compared with controls without a developmental disorder. Only salivary cortisol was considered as biological stress measure. Results Thirty-one studies were reviewed. Significantly higher self- and parent-reported emotional stress levels were found in individuals with ASD compared to controls. Regarding biological stress, the few studies in adults reported comparable cortisol stress responses and rhythms between both groups. In children/adolescents with ASD relative to controls, an increased, blunted, or similar cortisol stress response was reported, whereas the CAR did not differ in most studies, and diurnal rhythm was described as blunted or similar. Most studies found no significant association between parent-reported emotional stress and biological stress in ASD. Conclusions Current findings suggest that heightened emotional stress is a clinically significant factor in ASD. To unravel the cortisol response and rhythm, research in specific subgroups within the ASD spectrum is warranted, aiming at a higher frequency of cortisol measurements, preferably combined with momentary emotional stress measurements. En ligne : https://doi.org/10.1016/j.rasd.2022.102039 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Emotional stress, cortisol response, and cortisol rhythm in autism spectrum disorders: A systematic review [Texte imprimé et/ou numérique] / Kim VAN DER LINDEN, Auteur ; Claudia SIMONS, Auteur ; Thérèse VAN AMELSVOORT, Auteur ; Machteld MARCELIS, Auteur . - 102039. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 98 (October 2022) . - 102039 Mots-clés : Autism spectrum disorder  Stress  Cortisol  Cortisol awakening response Index. décimale : PER Périodiques Résumé : Background This systematic review evaluated whether there is evidence for (i) increased emotional stress levels, and (ii) a different biological stress response or rhythm [i.e., cortisol stress response, diurnal rhythm, or cortisol awakening response (CAR)] in individuals with autism spectrum disorder (ASD) relative to controls. Thirdly, the evidence for an association between emotional and biological stress in ASD was reviewed. Method MEDLINE, Cochrane Library, and SAGE journals were searched until December 2020. In this review, there were no limitations regarding age, sex, or intelligence quotient. Studies were only reviewed if results were compared with controls without a developmental disorder. Only salivary cortisol was considered as biological stress measure. Results Thirty-one studies were reviewed. Significantly higher self- and parent-reported emotional stress levels were found in individuals with ASD compared to controls. Regarding biological stress, the few studies in adults reported comparable cortisol stress responses and rhythms between both groups. In children/adolescents with ASD relative to controls, an increased, blunted, or similar cortisol stress response was reported, whereas the CAR did not differ in most studies, and diurnal rhythm was described as blunted or similar. Most studies found no significant association between parent-reported emotional stress and biological stress in ASD. Conclusions Current findings suggest that heightened emotional stress is a clinically significant factor in ASD. To unravel the cortisol response and rhythm, research in specific subgroups within the ASD spectrum is warranted, aiming at a higher frequency of cortisol measurements, preferably combined with momentary emotional stress measurements. En ligne : https://doi.org/10.1016/j.rasd.2022.102039 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents / Andrea OSKIS in Journal of Child Psychology and Psychiatry, 52-2 (February 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-2 (February 2011) . - p.111-118 Titre : Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Andrea OSKIS, Auteur ; Catherine LOVEDAY, Auteur ; Frank HUCKELBRIDGE, Auteur ; Lisa THORN, Auteur ; Angela CLOW, Auteur Année de publication : 2011 Article en page(s) : p.111-118 Langues : Anglais (eng) Mots-clés : Adolescence  attachment  CAR  cortisol  HPA axis Index. décimale : PER Périodiques Résumé : Background:  Attachment style has been linked with basal cortisol secretion in healthy adult women. We investigated whether dysregulation in basal cortisol secretion may be evident in younger healthy females. Methods:  Sixty healthy females aged 9–18 years (mean 14.16, SD ± 2.63 years) participated in the Attachment Style Interview (ASI). Eight saliva samples, synchronised to awakening, were collected per day on two consecutive weekdays to examine the cortisol awakening response (CAR) and the subsequent diurnal decline. Results:  Participants exhibiting an anxious attachment style had higher cortisol levels on awakening, in contrast to those who were securely attached. The anxious insecure group also showed an attenuated CAR compared to all other participants. Attachment style groups did not differ in cortisol secretion over the remainder of the day. Conclusions:  These findings indicate that the same pattern of cortisol dysregulation associated with disorder in adulthood manifests as a function of anxious (but not avoidant) insecure attachment style in females during healthy childhood and adolescence. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02296.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115 [article] Anxious attachment style and salivary cortisol dysregulation in healthy female children and adolescents [Texte imprimé et/ou numérique] / Andrea OSKIS, Auteur ; Catherine LOVEDAY, Auteur ; Frank HUCKELBRIDGE, Auteur ; Lisa THORN, Auteur ; Angela CLOW, Auteur . - 2011 . - p.111-118. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-2 (February 2011) . - p.111-118 Mots-clés : Adolescence  attachment  CAR  cortisol  HPA axis Index. décimale : PER Périodiques Résumé : Background:  Attachment style has been linked with basal cortisol secretion in healthy adult women. We investigated whether dysregulation in basal cortisol secretion may be evident in younger healthy females. Methods:  Sixty healthy females aged 9–18 years (mean 14.16, SD ± 2.63 years) participated in the Attachment Style Interview (ASI). Eight saliva samples, synchronised to awakening, were collected per day on two consecutive weekdays to examine the cortisol awakening response (CAR) and the subsequent diurnal decline. Results:  Participants exhibiting an anxious attachment style had higher cortisol levels on awakening, in contrast to those who were securely attached. The anxious insecure group also showed an attenuated CAR compared to all other participants. Attachment style groups did not differ in cortisol secretion over the remainder of the day. Conclusions:  These findings indicate that the same pattern of cortisol dysregulation associated with disorder in adulthood manifests as a function of anxious (but not avoidant) insecure attachment style in females during healthy childhood and adolescence. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02296.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115

Comparing oxytocin and cortisol regulation in a double-blind, placebo-controlled, hydrocortisone challenge pilot study in children with autism and typical development / B. A. CORBETT in Journal of Neurodevelopmental Disorders, 8-1 (December 2016)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.32 Titre : Comparing oxytocin and cortisol regulation in a double-blind, placebo-controlled, hydrocortisone challenge pilot study in children with autism and typical development Type de document : Texte imprimé et/ou numérique Auteurs : B. A. CORBETT, Auteur ; Karen L. BALES, Auteur ; D. SWAIN, Auteur ; K. SANDERS, Auteur ; T. A. WEINSTEIN, Auteur ; L. J. MUGLIA, Auteur Article en page(s) : p.32 Langues : Anglais (eng) Mots-clés : Arginine vasopressin  Autism  Autism spectrum disorder  Cortisol  Hormone  Hydrocortisone  LHPA axis  Oxytocin  Stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with autism spectrum disorder (ASD) show marked impairment in social functioning and poor adaptation to new and changing contexts, which may be influenced by underlying regulatory processes. Oxytocin (OT) and cortisol are key neuromodulators of biological and behavioral responses, show a synergistic effect, and have been implicated in the neuropathological profile in ASD. However, they are rarely investigated together. The purpose of the pilot study was to evaluate the relationship between cortisol and OT in children with ASD under baseline and physiological stress (hydrocortisone challenge) conditions. Arginine vasopressin (AVP), structurally similar to OT, was also examined. METHODS: A double-blind, placebo-controlled, randomly assigned, crossover design was employed in 25 children 8-to-12 years with ASD (N = 14) or typical development (TD, N = 11). A low dose of hydrocortisone and placebo were administered via liquid suspension. Analysis of variance (ANOVA) was used to examine the within-subject factor "Condition" (hydrocortisone/placebo) and "Time" (pre and post) and the between-subject factor "Group" (ASD vs. TD). Pearson correlations examined the relationship between hormone levels and clinical profile. RESULTS: There was a significant Time x Condition x Group interaction F (1.23) = 4.18, p = 0.05 showing a rise in OT during the experimental condition (hydrocortisone) and a drop during the placebo condition for the TD group but not the ASD group. There were no group differences for AVP. Hormone levels were associated with social profiles. CONCLUSIONS: For the TD group, an inverse relationship was observed. OT increased during physiological challenge suggesting that OT played a stress-buffering role during cortisol administration. In contrast for the ASD group, OT remained unchanged or decreased during both the physiological challenge and the placebo condition, suggesting that OT failed to serve as a stress buffer under conditions of physiological stress. While OT has been tied to the social ability of children with ASD, the diminished moderating effect of OT on cortisol may also play a contributory role in the heightened stress often observed in children with ASD. These results contribute to our understanding of the growing complexity of the effects of OT on social behavior as well as the functional interplay and differential regulation OT may have on stress modulation. En ligne : http://dx.doi.org/10.1186/s11689-016-9165-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349 [article] Comparing oxytocin and cortisol regulation in a double-blind, placebo-controlled, hydrocortisone challenge pilot study in children with autism and typical development [Texte imprimé et/ou numérique] / B. A. CORBETT, Auteur ; Karen L. BALES, Auteur ; D. SWAIN, Auteur ; K. SANDERS, Auteur ; T. A. WEINSTEIN, Auteur ; L. J. MUGLIA, Auteur . - p.32. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.32 Mots-clés : Arginine vasopressin  Autism  Autism spectrum disorder  Cortisol  Hormone  Hydrocortisone  LHPA axis  Oxytocin  Stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with autism spectrum disorder (ASD) show marked impairment in social functioning and poor adaptation to new and changing contexts, which may be influenced by underlying regulatory processes. Oxytocin (OT) and cortisol are key neuromodulators of biological and behavioral responses, show a synergistic effect, and have been implicated in the neuropathological profile in ASD. However, they are rarely investigated together. The purpose of the pilot study was to evaluate the relationship between cortisol and OT in children with ASD under baseline and physiological stress (hydrocortisone challenge) conditions. Arginine vasopressin (AVP), structurally similar to OT, was also examined. METHODS: A double-blind, placebo-controlled, randomly assigned, crossover design was employed in 25 children 8-to-12 years with ASD (N = 14) or typical development (TD, N = 11). A low dose of hydrocortisone and placebo were administered via liquid suspension. Analysis of variance (ANOVA) was used to examine the within-subject factor "Condition" (hydrocortisone/placebo) and "Time" (pre and post) and the between-subject factor "Group" (ASD vs. TD). Pearson correlations examined the relationship between hormone levels and clinical profile. RESULTS: There was a significant Time x Condition x Group interaction F (1.23) = 4.18, p = 0.05 showing a rise in OT during the experimental condition (hydrocortisone) and a drop during the placebo condition for the TD group but not the ASD group. There were no group differences for AVP. Hormone levels were associated with social profiles. CONCLUSIONS: For the TD group, an inverse relationship was observed. OT increased during physiological challenge suggesting that OT played a stress-buffering role during cortisol administration. In contrast for the ASD group, OT remained unchanged or decreased during both the physiological challenge and the placebo condition, suggesting that OT failed to serve as a stress buffer under conditions of physiological stress. While OT has been tied to the social ability of children with ASD, the diminished moderating effect of OT on cortisol may also play a contributory role in the heightened stress often observed in children with ASD. These results contribute to our understanding of the growing complexity of the effects of OT on social behavior as well as the functional interplay and differential regulation OT may have on stress modulation. En ligne : http://dx.doi.org/10.1186/s11689-016-9165-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349

Comparing the effects of age, pubertal development, and symptom profile on cortisol rhythm in children and adolescents with autism spectrum disorder / A. MUSCATELLO RACHAEL in Autism Research, 11-1 (January 2018)  

Public ISBD [article]  inAutism Research > 11-1 (January 2018) . - p.110-120 Titre : Comparing the effects of age, pubertal development, and symptom profile on cortisol rhythm in children and adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : A. MUSCATELLO RACHAEL, Auteur ; A. CORBETT BLYTHE, Auteur Article en page(s) : p.110-120 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  cortisol  HPA axis  age  development  puberty  adolescents Index. décimale : PER Périodiques Résumé : Previous studies in children with autism spectrum disorder (ASD) have shown elevated evening cortisol; however, few studies have examined diurnal rhythm in adolescents with ASD. Adolescence is a time of significant physical and psychological change, and dysregulation of the hypothalamic?pituitary?adrenal axis may put adolescents with ASD at increased risk for internalizing disorders, such as anxiety and depression. The extent to which cortisol levels are associated with age, puberty and symptom profile was examined in 113 youth (ages 7?17) with ASD and typical development. Salivary samples were collected over 3 days in the home, 4 times per day (waking, 30?min post?waking, afternoon, evening). Results showed youth with ASD had higher evening cortisol and a blunted diurnal slope relative to TD youth. Pubertal development and age were significant predictors of evening cortisol, and adolescents with ASD had higher evening cortisol levels compared to children with ASD. The study extends previous reports of elevated evening cortisol in children with ASD to reveal high levels in adolescence as well. Adolescents with ASD also show a significantly blunted diurnal slope, which may be associated with risk of internalizing symptoms. Findings suggest elevated evening cortisol persists across development in youth with ASD, thus emphasizing a need to identify potential negative effects of excess cortisol exposure on health in ASD individuals. Autism Res 2018, 11: 110?120. ? 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Elevations in stress hormone, cortisol, during the evening may indicate increased stress from changes throughout the day in youth with autism spectrum disorder (ASD). The current study shows that age and pubertal development are also related to increases in evening cortisol, and this maladaptive elevation in cortisol in ASD is not going away with age. These cortisol elevations may also be associated with other psychological symptoms and warrant further investigation in adolescents with ASD. En ligne : https://doi.org/10.1002/aur.1879 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334 [article] Comparing the effects of age, pubertal development, and symptom profile on cortisol rhythm in children and adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / A. MUSCATELLO RACHAEL, Auteur ; A. CORBETT BLYTHE, Auteur . - p.110-120. Langues : Anglais (eng) in Autism Research > 11-1 (January 2018) . - p.110-120 Mots-clés : autism spectrum disorder  cortisol  HPA axis  age  development  puberty  adolescents Index. décimale : PER Périodiques Résumé : Previous studies in children with autism spectrum disorder (ASD) have shown elevated evening cortisol; however, few studies have examined diurnal rhythm in adolescents with ASD. Adolescence is a time of significant physical and psychological change, and dysregulation of the hypothalamic?pituitary?adrenal axis may put adolescents with ASD at increased risk for internalizing disorders, such as anxiety and depression. The extent to which cortisol levels are associated with age, puberty and symptom profile was examined in 113 youth (ages 7?17) with ASD and typical development. Salivary samples were collected over 3 days in the home, 4 times per day (waking, 30?min post?waking, afternoon, evening). Results showed youth with ASD had higher evening cortisol and a blunted diurnal slope relative to TD youth. Pubertal development and age were significant predictors of evening cortisol, and adolescents with ASD had higher evening cortisol levels compared to children with ASD. The study extends previous reports of elevated evening cortisol in children with ASD to reveal high levels in adolescence as well. Adolescents with ASD also show a significantly blunted diurnal slope, which may be associated with risk of internalizing symptoms. Findings suggest elevated evening cortisol persists across development in youth with ASD, thus emphasizing a need to identify potential negative effects of excess cortisol exposure on health in ASD individuals. Autism Res 2018, 11: 110?120. ? 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Elevations in stress hormone, cortisol, during the evening may indicate increased stress from changes throughout the day in youth with autism spectrum disorder (ASD). The current study shows that age and pubertal development are also related to increases in evening cortisol, and this maladaptive elevation in cortisol in ASD is not going away with age. These cortisol elevations may also be associated with other psychological symptoms and warrant further investigation in adolescents with ASD. En ligne : https://doi.org/10.1002/aur.1879 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=334

Do testosterone and cortisol levels moderate aggressive responses to peer victimization in adolescents? / Izaskun ORUE in Development and Psychopathology, 36-2 (May 2024)  

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Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty / Katharina KIRCANSKI in Development and Psychopathology, 31-3 (August 2019)  

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Elevated levels of cortisol, brain-derived neurotropic factor and tissue plasminogen activator in male children with autism spectrum disorder / H. BOZKURT in Autism Research, 14-10 (October 2021)  

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Enhanced Cortisol Response to Stress in Children in Autism / Eve SPRATT in Journal of Autism and Developmental Disorders, 42-1 (January 2012)  

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Experiences of adversity in childhood and adolescence and cortisol in late adolescence / Courtenay L. KESSLER in Development and Psychopathology, 35-3 (August 2023)  

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