Facing ambiguity: Social threat sensitivity mediates the association between peer victimization and adolescent anxiety / Hannah L. SCHACTER in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.112-120 Titre : Facing ambiguity: Social threat sensitivity mediates the association between peer victimization and adolescent anxiety Type de document : texte imprimé Auteurs : Hannah L. SCHACTER, Auteur ; Hilary A. MARUSAK, Auteur ; Breanna A. BORG, Auteur ; Tanja JOVANOVIC, Auteur Article en page(s) : p.112-120 Langues : Anglais (eng) Mots-clés : adolescence  anxiety  peer victimization  threat sensitivity Index. décimale : PER Périodiques Résumé : Peer victimization is a developmentally salient stressor that elevates adolescents' risk for anxiety disorders. However, modifiable mechanisms that explain this link and can be targeted via therapeutic interventions remain poorly understood. Drawing from psychobiological models implicating aberrant threat sensitivity in the development and maintenance of psychopathology, the current study investigated sensitivity to peer-related social threats as a mechanism underlying the association between peer victimization and anxiety. A sample of 197 dyads of early adolescents (Mage = 12.02; 46% female) and parents/guardians (Mage = 41.46; 90% female) completed online surveys assessing peer victimization, sensitivity to potential (i.e., ambiguous) social threats, and anxiety. Controlling for potentially confounding demographic and psychosocial factors, both self- and parent-reported peer victimization were positively associated with adolescent anxiety symptoms. Additionally, there were significant indirect effects from self- and parent-reported peer victimization to anxiety via social threat sensitivity. Supplemental analyses indicated unique effects of covert, but not overt, peer victimization on social threat sensitivity and anxiety. The findings provide initial evidence that peer victimization experiences lower adolescents' threshold for interpreting threats in ambiguous social situations, which contributes to heightened anxiety. These results implicate social threat sensitivity as a potential therapeutic target for interrupting links from peer victimization to psychological distress. En ligne : https://dx.doi.org/10.1017/S0954579422001018 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Facing ambiguity: Social threat sensitivity mediates the association between peer victimization and adolescent anxiety [texte imprimé] / Hannah L. SCHACTER, Auteur ; Hilary A. MARUSAK, Auteur ; Breanna A. BORG, Auteur ; Tanja JOVANOVIC, Auteur . - p.112-120. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.112-120 Mots-clés : adolescence  anxiety  peer victimization  threat sensitivity Index. décimale : PER Périodiques Résumé : Peer victimization is a developmentally salient stressor that elevates adolescents' risk for anxiety disorders. However, modifiable mechanisms that explain this link and can be targeted via therapeutic interventions remain poorly understood. Drawing from psychobiological models implicating aberrant threat sensitivity in the development and maintenance of psychopathology, the current study investigated sensitivity to peer-related social threats as a mechanism underlying the association between peer victimization and anxiety. A sample of 197 dyads of early adolescents (Mage = 12.02; 46% female) and parents/guardians (Mage = 41.46; 90% female) completed online surveys assessing peer victimization, sensitivity to potential (i.e., ambiguous) social threats, and anxiety. Controlling for potentially confounding demographic and psychosocial factors, both self- and parent-reported peer victimization were positively associated with adolescent anxiety symptoms. Additionally, there were significant indirect effects from self- and parent-reported peer victimization to anxiety via social threat sensitivity. Supplemental analyses indicated unique effects of covert, but not overt, peer victimization on social threat sensitivity and anxiety. The findings provide initial evidence that peer victimization experiences lower adolescents' threshold for interpreting threats in ambiguous social situations, which contributes to heightened anxiety. These results implicate social threat sensitivity as a potential therapeutic target for interrupting links from peer victimization to psychological distress. En ligne : https://dx.doi.org/10.1017/S0954579422001018 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Research Review: What we have learned about the endocannabinoid system in developmental psychopathology / Ryann C. TANSEY in Journal of Child Psychology and Psychiatry, 66-12 (December 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-12 (December 2025) . - p.1904-1915 Titre : Research Review: What we have learned about the endocannabinoid system in developmental psychopathology Type de document : texte imprimé Auteurs : Ryann C. TANSEY, Auteur ; Marc D. FERGER, Auteur ; Hilary A. MARUSAK, Auteur ; Leah M. MAYO, Auteur Article en page(s) : p.1904-1915 Langues : Anglais (eng) Mots-clés : Endocannabinoid  2-arachidonoylglycerol  anandamide  psychopathology  development Index. décimale : PER Périodiques Résumé : Background The endocannabinoid (eCB) system, the primary target of cannabis, has gained significant attention as a potential novel therapeutic approach for treating a range of psychiatric disorders characterized by dysregulation of stress, emotion, and social behavior. The use of cannabis itself as a pharmacotherapeutic in children and adolescents is limited due to various constraints, including legal status, stigma, and real or perceived negative side effects. Thus, compounds that target the eCB system without the notable unwanted effects of cannabis may offer a more viable approach for developing populations. Methods In this narrative review, we provide an overview of the eCB system, summarizing its function throughout development and its potential contribution to psychopathology in children and adolescents. We highlight evidence of its behavioral role and the dysregulation of this system in various psychiatric disorders. Finally, we summarize current investigations into pharmacological and nonpharmacological therapeutic interventions designed to target the eCB system. Conclusions The eCB system may offer an innovative target for treatments of various psychiatric disorders in child and adolescent populations. However, more research is needed to understand the nuanced developmental trajectory of this system and to determine whether existing compounds are safe and effective for use in these populations. En ligne : https://doi.org/10.1111/jcpp.70006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573 [article] Research Review: What we have learned about the endocannabinoid system in developmental psychopathology [texte imprimé] / Ryann C. TANSEY, Auteur ; Marc D. FERGER, Auteur ; Hilary A. MARUSAK, Auteur ; Leah M. MAYO, Auteur . - p.1904-1915. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-12 (December 2025) . - p.1904-1915 Mots-clés : Endocannabinoid  2-arachidonoylglycerol  anandamide  psychopathology  development Index. décimale : PER Périodiques Résumé : Background The endocannabinoid (eCB) system, the primary target of cannabis, has gained significant attention as a potential novel therapeutic approach for treating a range of psychiatric disorders characterized by dysregulation of stress, emotion, and social behavior. The use of cannabis itself as a pharmacotherapeutic in children and adolescents is limited due to various constraints, including legal status, stigma, and real or perceived negative side effects. Thus, compounds that target the eCB system without the notable unwanted effects of cannabis may offer a more viable approach for developing populations. Methods In this narrative review, we provide an overview of the eCB system, summarizing its function throughout development and its potential contribution to psychopathology in children and adolescents. We highlight evidence of its behavioral role and the dysregulation of this system in various psychiatric disorders. Finally, we summarize current investigations into pharmacological and nonpharmacological therapeutic interventions designed to target the eCB system. Conclusions The eCB system may offer an innovative target for treatments of various psychiatric disorders in child and adolescent populations. However, more research is needed to understand the nuanced developmental trajectory of this system and to determine whether existing compounds are safe and effective for use in these populations. En ligne : https://doi.org/10.1111/jcpp.70006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573

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