Affective and psychotic reactivity to daily-life stress in adults with 22q11DS: a study using the experience sampling method / Maude SCHNEIDER in Journal of Neurodevelopmental Disorders, 12 (2020)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 12 (2020) Titre : Affective and psychotic reactivity to daily-life stress in adults with 22q11DS: a study using the experience sampling method Type de document : texte imprimé Auteurs : Maude SCHNEIDER, Auteur ; Thomas VAESSEN, Auteur ; Esther D.A. VAN DUIN, Auteur ; Zuzana KASANOVA, Auteur ; Wolfgang VIECHTBAUER, Auteur ; Ulrich REININGHAUS, Auteur ; Claudia VINGERHOETS, Auteur ; Jan BOOIJ, Auteur ; Ann SWILLEN, Auteur ; Jacob A.S. VORSTMAN, Auteur ; Thérèse VAN AMELSVOORT, Auteur ; Inez MYIN-GERMEYS, Auteur Langues : Anglais (eng) Mots-clés : Adult  DiGeorge Syndrome  Ecological Momentary Assessment  Humans  Mental Disorders  Psychotic Disorders/complications  Stress, Psychological/complications  22q11.2 deletion syndrome  Experience sampling method  Momentary psychotic experiences  Negative affect  Positive affect  Stress reactivity Index. décimale : PER Périodiques Résumé : BACKGROUND: 22q11.2 deletion syndrome (22q11DS) is a genetic disorder associated with an increased risk of psychiatric disorders. Vulnerability for psychopathology has been related to an increased reactivity to stress. Here, we examined affective states, perceived stress, affective and psychotic reactivity to various sources of environmental stress using the experience sampling method (ESM), a structured diary technique allowing repeated assessments in the context of daily life. METHODS: Adults with 22q11DS (n = 31; age, 34.1 years) and matched healthy controls (HCs; n = 24; age, 39.9 years) were included. ESM was used to assess affective states, perceived stress, and stress reactivity. Data were analyzed using multilevel regression models. RESULTS: Adults with 22q11DS displayed overall higher levels of negative affect but comparable levels of positive affect compared to HCs. Higher levels of perceived stress were reported by individuals with 22q11DS. Comparable affective and psychotic reactivity in relation to all types of environmental stress was observed between the two groups. CONCLUSION: The results point toward higher levels of negative affect and differences in the perception of daily hassles in 22q11DS but no difference in affective or psychotic reactivity to stress. This study contributes to the growing literature regarding the impact of stress on the development of psychopathology in the 22q11DS population. En ligne : https://dx.doi.org/10.1186/s11689-020-09333-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573 [article] Affective and psychotic reactivity to daily-life stress in adults with 22q11DS: a study using the experience sampling method [texte imprimé] / Maude SCHNEIDER, Auteur ; Thomas VAESSEN, Auteur ; Esther D.A. VAN DUIN, Auteur ; Zuzana KASANOVA, Auteur ; Wolfgang VIECHTBAUER, Auteur ; Ulrich REININGHAUS, Auteur ; Claudia VINGERHOETS, Auteur ; Jan BOOIJ, Auteur ; Ann SWILLEN, Auteur ; Jacob A.S. VORSTMAN, Auteur ; Thérèse VAN AMELSVOORT, Auteur ; Inez MYIN-GERMEYS, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 12 (2020) Mots-clés : Adult  DiGeorge Syndrome  Ecological Momentary Assessment  Humans  Mental Disorders  Psychotic Disorders/complications  Stress, Psychological/complications  22q11.2 deletion syndrome  Experience sampling method  Momentary psychotic experiences  Negative affect  Positive affect  Stress reactivity Index. décimale : PER Périodiques Résumé : BACKGROUND: 22q11.2 deletion syndrome (22q11DS) is a genetic disorder associated with an increased risk of psychiatric disorders. Vulnerability for psychopathology has been related to an increased reactivity to stress. Here, we examined affective states, perceived stress, affective and psychotic reactivity to various sources of environmental stress using the experience sampling method (ESM), a structured diary technique allowing repeated assessments in the context of daily life. METHODS: Adults with 22q11DS (n = 31; age, 34.1 years) and matched healthy controls (HCs; n = 24; age, 39.9 years) were included. ESM was used to assess affective states, perceived stress, and stress reactivity. Data were analyzed using multilevel regression models. RESULTS: Adults with 22q11DS displayed overall higher levels of negative affect but comparable levels of positive affect compared to HCs. Higher levels of perceived stress were reported by individuals with 22q11DS. Comparable affective and psychotic reactivity in relation to all types of environmental stress was observed between the two groups. CONCLUSION: The results point toward higher levels of negative affect and differences in the perception of daily hassles in 22q11DS but no difference in affective or psychotic reactivity to stress. This study contributes to the growing literature regarding the impact of stress on the development of psychopathology in the 22q11DS population. En ligne : https://dx.doi.org/10.1186/s11689-020-09333-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=573

Unraveling psychosis risk in sexual minorities: temporal dynamics of social defeat and suspiciousness in adolescence / Margaux SAGEOT in Journal of Child Psychology and Psychiatry, 67-2 (February 2026)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 67-2 (February 2026) . - p.296-304 Titre : Unraveling psychosis risk in sexual minorities: temporal dynamics of social defeat and suspiciousness in adolescence Type de document : texte imprimé Auteurs : Margaux SAGEOT, Auteur ; Robin ACHTERHOF, Auteur ; Anu P. HIEKKARANTA, Auteur ; Aleksandra LECEI, Auteur ; Kristof VANSTEELAND, Auteur ; Inez MYIN-GERMEYS, Auteur ; Ruud VAN WINKEL, Auteur Article en page(s) : p.296-304 Langues : Anglais (eng) Mots-clés : Psychotic experiences  sexual minority youth  belonging  ESM  exclusion Index. décimale : PER Périodiques Résumé : Background Previous research suggests that sexual minorities are at higher risk for psychotic experiences, possibly due to repeated social defeat experiences. However, empirical research investigating this hypothesis is largely lacking. This study examined how experiences of ?feeling excluded? and ?not belonging? impact the prospective development of psychotic experiences in an adolescent sexual minority group, defined here as non-heterosexual attraction to others. Methods Experience sampling method (ESM) data from 1913 Flemish adolescents (aged 11?20) in the SIGMA study were analyzed. They reported their momentary feelings of exclusion when alone, belonging when in the company of others (both operationalizations of social defeat), and suspiciousness. Multilevel linear regression models tested the bidirectional, within- and between-person associations between social defeat and suspiciousness, and the effects of sexual minority status. Results Lower feelings of belonging when in company significantly predicted higher suspiciousness at the next beep [95% CI: ?0.03, ?0.01], whereas increased feelings of exclusion when alone did not. Moreover, suspiciousness did not significantly predict feelings of exclusion and belonging at the next beep, confirming the direction of effect. Sexual minority participants reported generally lower belonging in social settings [95% CI: ?0.68, ?0.29] and higher suspiciousness [95% CI: 0.16, 0.57], but not higher feelings of exclusion. The interaction between social defeat and sexual minority status was not significant, indicating no differential sensitivity to social defeat experiences. Conclusions The experience of ?not fitting in? when in company may be the most poignant social factor increasing risk for psychotic experiences in sexual minority youth. The findings highlight the need for inclusive environments where sexual minority individuals feel supported and integrated. En ligne : https://doi.org/10.1111/jcpp.70042 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=579 [article] Unraveling psychosis risk in sexual minorities: temporal dynamics of social defeat and suspiciousness in adolescence [texte imprimé] / Margaux SAGEOT, Auteur ; Robin ACHTERHOF, Auteur ; Anu P. HIEKKARANTA, Auteur ; Aleksandra LECEI, Auteur ; Kristof VANSTEELAND, Auteur ; Inez MYIN-GERMEYS, Auteur ; Ruud VAN WINKEL, Auteur . - p.296-304. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 67-2 (February 2026) . - p.296-304 Mots-clés : Psychotic experiences  sexual minority youth  belonging  ESM  exclusion Index. décimale : PER Périodiques Résumé : Background Previous research suggests that sexual minorities are at higher risk for psychotic experiences, possibly due to repeated social defeat experiences. However, empirical research investigating this hypothesis is largely lacking. This study examined how experiences of ?feeling excluded? and ?not belonging? impact the prospective development of psychotic experiences in an adolescent sexual minority group, defined here as non-heterosexual attraction to others. Methods Experience sampling method (ESM) data from 1913 Flemish adolescents (aged 11?20) in the SIGMA study were analyzed. They reported their momentary feelings of exclusion when alone, belonging when in the company of others (both operationalizations of social defeat), and suspiciousness. Multilevel linear regression models tested the bidirectional, within- and between-person associations between social defeat and suspiciousness, and the effects of sexual minority status. Results Lower feelings of belonging when in company significantly predicted higher suspiciousness at the next beep [95% CI: ?0.03, ?0.01], whereas increased feelings of exclusion when alone did not. Moreover, suspiciousness did not significantly predict feelings of exclusion and belonging at the next beep, confirming the direction of effect. Sexual minority participants reported generally lower belonging in social settings [95% CI: ?0.68, ?0.29] and higher suspiciousness [95% CI: 0.16, 0.57], but not higher feelings of exclusion. The interaction between social defeat and sexual minority status was not significant, indicating no differential sensitivity to social defeat experiences. Conclusions The experience of ?not fitting in? when in company may be the most poignant social factor increasing risk for psychotic experiences in sexual minority youth. The findings highlight the need for inclusive environments where sexual minority individuals feel supported and integrated. En ligne : https://doi.org/10.1111/jcpp.70042 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=579

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