Burden of ASD in children and adolescents in the WPR: An age-period-cohort analysis for the GBD 2021 / Jing CHEN in Research in Autism, 131 (March 2026)  

Public ISBD [article]  inResearch in Autism > 131 (March 2026) . - 202817 Titre : Burden of ASD in children and adolescents in the WPR: An age-period-cohort analysis for the GBD 2021 Type de document : texte imprimé Auteurs : Jing CHEN, Auteur ; Lirong HUANG, Auteur ; Yan YANG, Auteur ; Xinguang ZHANG, Auteur ; Shuxia WANG, Auteur ; Zheng XUE, Auteur Article en page(s) : 202817 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Western Pacific Region  Youth  Epidemiology  Global Burden of Disease study Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental condition with early-onset symptoms. The burden of ASD among children and adolescents in the Western Pacific Region (WPR) is largely unknown. This study provides an overview of recent ASD prevalence and trends in the WPR to inform prevention and intervention strategies. Methods Data from the Global Burden of Disease 2021 study were analyzed, focusing on children and adolescents aged 0–19 years in the WPR. The analysis included prevalence, incidence, and disability-adjusted life years (DALYs) across regions, ages, genders, and income levels from 1992 to 2021. Results In 2021, there were an estimated 22,429,930 (95 % uncertainty interval [UI] 18,910,216–26,372,501) prevalent cases, 1,163,706 (95 % UI 981,645–1,371,347) incident cases, and 4,306,131 (95 % UI 2,915,975–6,056,810) DALYs due to ASD in the WPR. The age-standardized prevalence and DALYs increased by 0.1 % and 0.12 % annually, while incidence decreased by 0.08 %. A key finding was the pronounced and growing inequality: the ASD burden was disproportionately concentrated in high-income regions, and the gap in prevalence between high- and low-income regions widened over the study period. Additionally, the prevalence among males was over twofold higher than that among females. Conclusion The burden of ASD in the WPR has increased over the past three decades, revealing substantial and widening socioeconomic and gender disparities. Our findings underscore the urgent need for enhanced detection, diagnosis, and intervention services, with targeted efforts to bridge the inequality gap, especially for females and in low-income countries within the region. En ligne : https://doi.org/10.1016/j.reia.2026.202817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=581 [article] Burden of ASD in children and adolescents in the WPR: An age-period-cohort analysis for the GBD 2021 [texte imprimé] / Jing CHEN, Auteur ; Lirong HUANG, Auteur ; Yan YANG, Auteur ; Xinguang ZHANG, Auteur ; Shuxia WANG, Auteur ; Zheng XUE, Auteur . - 202817. Langues : Anglais (eng) in Research in Autism > 131 (March 2026) . - 202817 Mots-clés : Autism spectrum disorder  Western Pacific Region  Youth  Epidemiology  Global Burden of Disease study Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental condition with early-onset symptoms. The burden of ASD among children and adolescents in the Western Pacific Region (WPR) is largely unknown. This study provides an overview of recent ASD prevalence and trends in the WPR to inform prevention and intervention strategies. Methods Data from the Global Burden of Disease 2021 study were analyzed, focusing on children and adolescents aged 0–19 years in the WPR. The analysis included prevalence, incidence, and disability-adjusted life years (DALYs) across regions, ages, genders, and income levels from 1992 to 2021. Results In 2021, there were an estimated 22,429,930 (95 % uncertainty interval [UI] 18,910,216–26,372,501) prevalent cases, 1,163,706 (95 % UI 981,645–1,371,347) incident cases, and 4,306,131 (95 % UI 2,915,975–6,056,810) DALYs due to ASD in the WPR. The age-standardized prevalence and DALYs increased by 0.1 % and 0.12 % annually, while incidence decreased by 0.08 %. A key finding was the pronounced and growing inequality: the ASD burden was disproportionately concentrated in high-income regions, and the gap in prevalence between high- and low-income regions widened over the study period. Additionally, the prevalence among males was over twofold higher than that among females. Conclusion The burden of ASD in the WPR has increased over the past three decades, revealing substantial and widening socioeconomic and gender disparities. Our findings underscore the urgent need for enhanced detection, diagnosis, and intervention services, with targeted efforts to bridge the inequality gap, especially for females and in low-income countries within the region. En ligne : https://doi.org/10.1016/j.reia.2026.202817 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=581

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