120 recherche sur le mot-clé 'Epidemiology'

Epidemiology of Alzheimer Disease and Related Dementia Among Medicare and Medicaid Enrolled Autistic Adults, 2011-2019 / Samuel B. ROSENBERG ; Josue Antonio G. ESTRADA ; Marcia Pescador JIMENEZ ; Ashley SCOTT ; Alianna HIGGINS ; Eric RUBENSTEIN in Autism Research, 18-5 (May 2025)  

Public ISBD [article]  inAutism Research > 18-5 (May 2025) . - p.1077-1086 Titre : Epidemiology of Alzheimer Disease and Related Dementia Among Medicare and Medicaid Enrolled Autistic Adults, 2011-2019 Type de document : texte imprimé Auteurs : Samuel B. ROSENBERG, Auteur ; Josue Antonio G. ESTRADA, Auteur ; Marcia Pescador JIMENEZ, Auteur ; Ashley SCOTT, Auteur ; Alianna HIGGINS, Auteur ; Eric RUBENSTEIN, Auteur Article en page(s) : p.1077-1086 Langues : Anglais (eng) Mots-clés : Alzheimer disease  autism  dementia  disparity  epidemiology  intellectual disability  medicaid  medicare Index. décimale : PER Périodiques Résumé : ABSTRACT Alzheimer's disease and related dementias (ADRD) are burdensome and lethal conditions that have been hypothesized to be related to autism through shared genetic etiologies and environmental risk factors. Our objective was to use longitudinal Medicaid and Medicare data to describe the epidemiology of ADRD in publicly insured autistic adults. We used all claims and encounters from 2011 to 2019 to identify autism and ADRD. We calculated prevalence, incidence, age at onset, and created survival curves. There were 90,229 autistic adults ? 30 years of age and enrolled for at least 1 year in Medicaid and/or Medicare and 267 ADRD cases. Prevalence of ADRD was 2.09% (95% CI: 1.99%, 2.20%) in 2011 and 8.11% (95% CI: 7.92%, 8.30%) in 2019. Mean age at ADRD onset was 59.3 years (SD: 14.2). Mean age among men was 58.3 years (SD: 13.8) and 61.0 years among females. Incidence of ADRD was higher in autistic adults with intellectual disability with no difference by sex. ADRD is a prevalent condition in middle- and older-aged adults identified with autism in the Medicaid and Medicare system. Understanding the diagnostic process and phenotype of ADRD will be important to improve identification and treatment. En ligne : https://doi.org/10.1002/aur.70035 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558 [article] Epidemiology of Alzheimer Disease and Related Dementia Among Medicare and Medicaid Enrolled Autistic Adults, 2011-2019 [texte imprimé] / Samuel B. ROSENBERG, Auteur ; Josue Antonio G. ESTRADA, Auteur ; Marcia Pescador JIMENEZ, Auteur ; Ashley SCOTT, Auteur ; Alianna HIGGINS, Auteur ; Eric RUBENSTEIN, Auteur . - p.1077-1086. Langues : Anglais (eng) in Autism Research > 18-5 (May 2025) . - p.1077-1086 Mots-clés : Alzheimer disease  autism  dementia  disparity  epidemiology  intellectual disability  medicaid  medicare Index. décimale : PER Périodiques Résumé : ABSTRACT Alzheimer's disease and related dementias (ADRD) are burdensome and lethal conditions that have been hypothesized to be related to autism through shared genetic etiologies and environmental risk factors. Our objective was to use longitudinal Medicaid and Medicare data to describe the epidemiology of ADRD in publicly insured autistic adults. We used all claims and encounters from 2011 to 2019 to identify autism and ADRD. We calculated prevalence, incidence, age at onset, and created survival curves. There were 90,229 autistic adults ? 30 years of age and enrolled for at least 1 year in Medicaid and/or Medicare and 267 ADRD cases. Prevalence of ADRD was 2.09% (95% CI: 1.99%, 2.20%) in 2011 and 8.11% (95% CI: 7.92%, 8.30%) in 2019. Mean age at ADRD onset was 59.3 years (SD: 14.2). Mean age among men was 58.3 years (SD: 13.8) and 61.0 years among females. Incidence of ADRD was higher in autistic adults with intellectual disability with no difference by sex. ADRD is a prevalent condition in middle- and older-aged adults identified with autism in the Medicaid and Medicare system. Understanding the diagnostic process and phenotype of ADRD will be important to improve identification and treatment. En ligne : https://doi.org/10.1002/aur.70035 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558

Epidemiology of Injury-Related Emergency Department Visits in the US Among Youth with Autism Spectrum Disorder / Luther G. KALB in Journal of Autism and Developmental Disorders, 46-8 (August 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-8 (August 2016) . - p.2756-2763 Titre : Epidemiology of Injury-Related Emergency Department Visits in the US Among Youth with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Luther G. KALB, Auteur ; Roma A. VASA, Auteur ; Elizabeth D. BALLARD, Auteur ; Steven WOODS, Auteur ; Mitchell GOLDSTEIN, Auteur ; Holly C. WILCOX, Auteur Article en page(s) : p.2756-2763 Langues : Anglais (eng) Mots-clés : Autistic disorder  Injury  Epidemiology  Intellectual disability  Emergency medicine Index. décimale : PER Périodiques Résumé : Several reports suggest children with autism spectrum disorder (ASD) are more likely to be seen for injury-related ED visits; however, no nationally representative study has examined this question. Using data from the 2008 Nationwide Emergency Department Sample, over a quarter of all visits among those with ASD were related to injury. In the multivariate analyses, the odds of an injury-related visit was 54 % greater among those with ASD compared to youth with intellectual disability (ID), but 48 % less compared to youth without ID or ASD. Compared to all other pediatric injury-visits in the US, visits among children with ASD were more likely to be due to self-inflicted injury and poisoning and were more likely to result in hospitalization (all p < 0.001). En ligne : http://dx.doi.org/10.1007/s10803-016-2820-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=291 [article] Epidemiology of Injury-Related Emergency Department Visits in the US Among Youth with Autism Spectrum Disorder [texte imprimé] / Luther G. KALB, Auteur ; Roma A. VASA, Auteur ; Elizabeth D. BALLARD, Auteur ; Steven WOODS, Auteur ; Mitchell GOLDSTEIN, Auteur ; Holly C. WILCOX, Auteur . - p.2756-2763. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-8 (August 2016) . - p.2756-2763 Mots-clés : Autistic disorder  Injury  Epidemiology  Intellectual disability  Emergency medicine Index. décimale : PER Périodiques Résumé : Several reports suggest children with autism spectrum disorder (ASD) are more likely to be seen for injury-related ED visits; however, no nationally representative study has examined this question. Using data from the 2008 Nationwide Emergency Department Sample, over a quarter of all visits among those with ASD were related to injury. In the multivariate analyses, the odds of an injury-related visit was 54 % greater among those with ASD compared to youth with intellectual disability (ID), but 48 % less compared to youth without ID or ASD. Compared to all other pediatric injury-visits in the US, visits among children with ASD were more likely to be due to self-inflicted injury and poisoning and were more likely to result in hospitalization (all p < 0.001). En ligne : http://dx.doi.org/10.1007/s10803-016-2820-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=291

Autism epidemiology in Hong Kong children and youths aged 6–17: Implications on autism screening and sex differences in the community / Oscar WH WONG in Autism, 29-11 (November 2025)  

Public ISBD [article]  inAutism > 29-11 (November 2025) . - p.2872-2884 Titre : Autism epidemiology in Hong Kong children and youths aged 6–17: Implications on autism screening and sex differences in the community Type de document : texte imprimé Auteurs : Oscar WH WONG, Auteur ; Sandra SM CHAN, Auteur ; Steven WH CHAU, Auteur ; Winnie CW CHU, Auteur ; Carol SW HO, Auteur ; Stephy WS HO, Auteur ; Se-fong HUNG, Auteur ; Samara HUSSAIN, Auteur ; Kelly Y. C. LAI, Auteur ; Angela MW LAM, Auteur ; Holly HL LO, Auteur ; Karen KY MA, Auteur ; Suk Ling MA, Auteur ; Flora YM MO, Auteur ; Pak Chung SHAM, Auteur ; Caroline KS SHEA, Auteur ; Suzanne HW SO, Auteur ; Kelvin KF TSOI, Auteur ; Patrick Wl LEUNG, Auteur Article en page(s) : p.2872-2884 Langues : Anglais (eng) Mots-clés : Asian  autism  epidemiology  prevalence  screening  sex differences Index. décimale : PER Périodiques Résumé : Epidemiological studies on autism lack representation from Asia. We estimated the prevalence of autism among children and youths in Hong Kong using a two-stage approach. In addition, we evaluated the psychometric properties of the screening instrument and explored sex differences within an epidemiological context. A random school-based sample of 5,865 children and youths were screened with the Autism Spectrum Quotient-10 (AQ-10). Then, a subsample of 317 participants underwent the Autism Diagnostic Interview-Revised assessment. Prevalence was estimated by applying positive and negative predictive values (PPV/NPV) of AQ-10 derived from the subsample to the entire cohort. None of the screened negative participants had autism, resulting in an NPV of 100%. Discrepant PPVs were noted for males (20.4%) and females (5.20%). The estimated prevalence was 2.57% using sex-specific PPVs. Explorative analysis on AQ-10 Positive participants without the diagnosis (i.e. ‘false positives’) showed significantly elevated autistic symptoms. The prevalence of autism in Hong Kong is comparable to the recent estimates in Western countries, which poses a significant public health challenge. Despite the high false-positive rates, AQ-10 remains valuable for excluding autism and identifying those with autistic symptoms. Furthermore, community-based studies are crucial to address sex differences in autism expression.Lay abstract Although studies have found that autism is becoming more common, little is known whether this is true in Asian countries. This study looked into how many children and teenagers in Hong Kong might have autism. We first screened 5,865 school-aged children and youths with the Autism Spectrum Quotient-10 (AQ-10). Then, we conducted in-depth interviews with 317 of them to assess for autism. We found that around 2.57% of children and youths aged 6–17 years in Hong Kong might have autism. This number is similar to that of the Western countries. Furthermore, we also discovered that boys who were screened positive on the AQ-10 were more likely to have autism than girls. This could be because autism is more common in boys, and the AQ-10 might be better at spotting autism in boys than in girls. In the future, studies will need to find an optimal way of detecting autism in the community, considering how autism may present differently in boys and girls. En ligne : https://dx.doi.org/10.1177/13623613251360269 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570 [article] Autism epidemiology in Hong Kong children and youths aged 6–17: Implications on autism screening and sex differences in the community [texte imprimé] / Oscar WH WONG, Auteur ; Sandra SM CHAN, Auteur ; Steven WH CHAU, Auteur ; Winnie CW CHU, Auteur ; Carol SW HO, Auteur ; Stephy WS HO, Auteur ; Se-fong HUNG, Auteur ; Samara HUSSAIN, Auteur ; Kelly Y. C. LAI, Auteur ; Angela MW LAM, Auteur ; Holly HL LO, Auteur ; Karen KY MA, Auteur ; Suk Ling MA, Auteur ; Flora YM MO, Auteur ; Pak Chung SHAM, Auteur ; Caroline KS SHEA, Auteur ; Suzanne HW SO, Auteur ; Kelvin KF TSOI, Auteur ; Patrick Wl LEUNG, Auteur . - p.2872-2884. Langues : Anglais (eng) in Autism > 29-11 (November 2025) . - p.2872-2884 Mots-clés : Asian  autism  epidemiology  prevalence  screening  sex differences Index. décimale : PER Périodiques Résumé : Epidemiological studies on autism lack representation from Asia. We estimated the prevalence of autism among children and youths in Hong Kong using a two-stage approach. In addition, we evaluated the psychometric properties of the screening instrument and explored sex differences within an epidemiological context. A random school-based sample of 5,865 children and youths were screened with the Autism Spectrum Quotient-10 (AQ-10). Then, a subsample of 317 participants underwent the Autism Diagnostic Interview-Revised assessment. Prevalence was estimated by applying positive and negative predictive values (PPV/NPV) of AQ-10 derived from the subsample to the entire cohort. None of the screened negative participants had autism, resulting in an NPV of 100%. Discrepant PPVs were noted for males (20.4%) and females (5.20%). The estimated prevalence was 2.57% using sex-specific PPVs. Explorative analysis on AQ-10 Positive participants without the diagnosis (i.e. ‘false positives’) showed significantly elevated autistic symptoms. The prevalence of autism in Hong Kong is comparable to the recent estimates in Western countries, which poses a significant public health challenge. Despite the high false-positive rates, AQ-10 remains valuable for excluding autism and identifying those with autistic symptoms. Furthermore, community-based studies are crucial to address sex differences in autism expression.Lay abstract Although studies have found that autism is becoming more common, little is known whether this is true in Asian countries. This study looked into how many children and teenagers in Hong Kong might have autism. We first screened 5,865 school-aged children and youths with the Autism Spectrum Quotient-10 (AQ-10). Then, we conducted in-depth interviews with 317 of them to assess for autism. We found that around 2.57% of children and youths aged 6–17 years in Hong Kong might have autism. This number is similar to that of the Western countries. Furthermore, we also discovered that boys who were screened positive on the AQ-10 were more likely to have autism than girls. This could be because autism is more common in boys, and the AQ-10 might be better at spotting autism in boys than in girls. In the future, studies will need to find an optimal way of detecting autism in the community, considering how autism may present differently in boys and girls. En ligne : https://dx.doi.org/10.1177/13623613251360269 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=570

Commentary: ‘Diseases of the world’: from epidemiology to etiology of child and adolescent psychopathology – a commentary on Polanczyk et al. () / Jane E. COSTELLO in Journal of Child Psychology and Psychiatry, 56-3 (March 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-3 (March 2015) . - p.366-369 Titre : Commentary: ‘Diseases of the world’: from epidemiology to etiology of child and adolescent psychopathology – a commentary on Polanczyk et al. () Type de document : texte imprimé Auteurs : Jane E. COSTELLO, Auteur Article en page(s) : p.366-369 Langues : Anglais (eng) Mots-clés : Epidemiology  etiology  global prevalence  child mental health disorders Index. décimale : PER Périodiques Résumé : If you are an epidemiologist, professionally interested in patterns of the distribution of disease in time and space, the first question you will be asked is ‘how many?’ What is the ‘prevalence rate’ of ADHD? How many children have autism? The second question will be ‘are there more nowadays?’ Is there an epidemic of childhood depression Is the rate of conduct disorder increasing? This seems to be the main use that clinicians and clinical researchers make of epidemiology. So epidemiology is seen as important for some purposes but, somehow, not scientifically relevant to the real job of treatment. According to this view, epidemiology's value lies in telling us how bad a problem is (the ‘burden of disease’), how many affected people are getting treatment, and what the likely costs are. All useful stuff, but not getting us any nearer to the holy grail of understanding causes and cures of the ‘diseases of the world’. In their ‘meta-analysis of the worldwide prevalence of mental disorders in children and adolescents’, Polanczyk and colleagues (Polanczyk et al., 2015, this issue) demonstrate just how partial and mistaken this view of epidemiology is. Polanczyk et al. have indeed provided a most valuable and thorough review of the descriptive issues that bureaucrats obsess about. But in the process they have illuminated several areas that are of real importance for the etiologic questions that scientists need to have answered if we are to make breakthroughs in the treatment and prevention of child and adolescent psychopathology. En ligne : http://dx.doi.org/10.1111/jcpp.12402 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Commentary: ‘Diseases of the world’: from epidemiology to etiology of child and adolescent psychopathology – a commentary on Polanczyk et al. () [texte imprimé] / Jane E. COSTELLO, Auteur . - p.366-369. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-3 (March 2015) . - p.366-369 Mots-clés : Epidemiology  etiology  global prevalence  child mental health disorders Index. décimale : PER Périodiques Résumé : If you are an epidemiologist, professionally interested in patterns of the distribution of disease in time and space, the first question you will be asked is ‘how many?’ What is the ‘prevalence rate’ of ADHD? How many children have autism? The second question will be ‘are there more nowadays?’ Is there an epidemic of childhood depression Is the rate of conduct disorder increasing? This seems to be the main use that clinicians and clinical researchers make of epidemiology. So epidemiology is seen as important for some purposes but, somehow, not scientifically relevant to the real job of treatment. According to this view, epidemiology's value lies in telling us how bad a problem is (the ‘burden of disease’), how many affected people are getting treatment, and what the likely costs are. All useful stuff, but not getting us any nearer to the holy grail of understanding causes and cures of the ‘diseases of the world’. In their ‘meta-analysis of the worldwide prevalence of mental disorders in children and adolescents’, Polanczyk and colleagues (Polanczyk et al., 2015, this issue) demonstrate just how partial and mistaken this view of epidemiology is. Polanczyk et al. have indeed provided a most valuable and thorough review of the descriptive issues that bureaucrats obsess about. But in the process they have illuminated several areas that are of real importance for the etiologic questions that scientists need to have answered if we are to make breakthroughs in the treatment and prevention of child and adolescent psychopathology. En ligne : http://dx.doi.org/10.1111/jcpp.12402 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Impact of DSM-5 on epidemiology of Autism Spectrum Disorder / Luke Y. TSAI in Research in Autism Spectrum Disorders, 8-11 (November 2014)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 8-11 (November 2014) . - p.1454-1470 Titre : Impact of DSM-5 on epidemiology of Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Luke Y. TSAI, Auteur Article en page(s) : p.1454-1470 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Autistic Disorder  Pervasive developmental disorder  DSM-5  Epidemiology  Prevalence Index. décimale : PER Périodiques Résumé : This paper extensively and comprehensively reviews the literature on epidemiology of autism focusing on the prevalence rates of Autistic Disorder (AD) and Autism Spectrum Disorder (ASD), and the potential negative impact of DSM-5 ASD on future ASD prevalence studies. Between 1966 and 2013, there are 72 published prevalence studies of AD and 61 published studies of ASD. The AD has a broad range of prevalence rates and has shown a trend of increasing rates over time. But there are also some evidences showing that the increase seems to have leveled off. The current prevalence of AD is estimated in the range of 10–30 per 10,000 people (i.e., 1 in 1000 to 1 in 333). The ASD also has a wide range of prevalence rates with a median rate of 69.5 per 10,000 people (1 in 144). When the prevalence rates are subdivided into several sub-ranges (e.g., 10–20, 20–40, etc. per 10,000), it is difficult to pick a particular sub-range to represent the prevalence of ASD. The present review notes that several recent studies comparing the utility of DSM-IV/DSM-IV-TR ASD and the DSM-5 ASD have reported that about 9–54% of DSM-IV ASD cases do not qualify for the DSM-5 ASD. Suggestions of research designs for future ASD prevalence studies are offered. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.07.016 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Impact of DSM-5 on epidemiology of Autism Spectrum Disorder [texte imprimé] / Luke Y. TSAI, Auteur . - p.1454-1470. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 8-11 (November 2014) . - p.1454-1470 Mots-clés : Autism Spectrum Disorder  Autistic Disorder  Pervasive developmental disorder  DSM-5  Epidemiology  Prevalence Index. décimale : PER Périodiques Résumé : This paper extensively and comprehensively reviews the literature on epidemiology of autism focusing on the prevalence rates of Autistic Disorder (AD) and Autism Spectrum Disorder (ASD), and the potential negative impact of DSM-5 ASD on future ASD prevalence studies. Between 1966 and 2013, there are 72 published prevalence studies of AD and 61 published studies of ASD. The AD has a broad range of prevalence rates and has shown a trend of increasing rates over time. But there are also some evidences showing that the increase seems to have leveled off. The current prevalence of AD is estimated in the range of 10–30 per 10,000 people (i.e., 1 in 1000 to 1 in 333). The ASD also has a wide range of prevalence rates with a median rate of 69.5 per 10,000 people (1 in 144). When the prevalence rates are subdivided into several sub-ranges (e.g., 10–20, 20–40, etc. per 10,000), it is difficult to pick a particular sub-range to represent the prevalence of ASD. The present review notes that several recent studies comparing the utility of DSM-IV/DSM-IV-TR ASD and the DSM-5 ASD have reported that about 9–54% of DSM-IV ASD cases do not qualify for the DSM-5 ASD. Suggestions of research designs for future ASD prevalence studies are offered. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.07.016 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

The International Collaboration for Autism Registry Epidemiology (iCARE): Multinational Registry-Based Investigations of Autism Risk Factors and Trends / Diana SCHENDEL in Journal of Autism and Developmental Disorders, 43-11 (November 2013)  

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The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network / Diana SCHENDEL in Journal of Autism and Developmental Disorders, 42-10 (October 2012)  

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Autism screening and diagnosis in low resource settings: Challenges and opportunities to enhance research and services worldwide / Maureen S. DURKIN in Autism Research, 8-5 (October 2015)  

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Epidemiological surveys of ASD: advances and remaining challenges / E. FOMBONNE in Journal of Autism and Developmental Disorders, 51-12 (December 2021)  

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Remembering Dr Li-Ching Lee, a pioneer of global autism research / E. RUBENSTEIN in Autism, 26-2 (February 2022)  

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