Defining and Measuring Developmental Regression During Childhood: A Scoping Review / Kirsten FURLEY in Autism Research, 19-9 (September 2026)  

Public ISBD [article]  inAutism Research > 19-9 (September 2026) . - p. e70325 Titre : Defining and Measuring Developmental Regression During Childhood: A Scoping Review Type de document : texte imprimé Auteurs : Kirsten FURLEY, Auteur ; Jenny FAIRTHORNE, Auteur ; Vishnu Priya Mohanakumar SINDHU, Auteur ; Katrina WILLIAMS, Auteur ; Amanda BRIGNELL, Auteur Article en page(s) : p. e70325 Langues : Anglais (eng) Mots-clés : child development disorders  definition  developmental disabilities  developmental regression  neurodevelopmental disorders  pervasive Index. décimale : PER Périodiques Résumé : ABSTRACT Developmental regression during childhood is inconsistently defined and measured, resulting in delayed diagnostic discovery and intervention. This study aimed to examine published definitions and measures for developmental regression. A comprehensive search strategy was applied to Medline, Embase, Cochrane, and PsycINFO databases. Reviewers independently screened relevant studies according to the Preferred Reporting Items for Systematic reviews. The number and percentages of definition use, their primary features, and measures were reported. Of 19,099 potential publications, 157 were included. Thematic analysis identified four condition groups: Neurodevelopmental disorders (n?=?118); Progressive neurodegenerative conditions (n?=?17); Developmental epileptic encephalopathies (n?=?8); and Genetic conditions (n?=?14). Most studies (n?=?124, 79.0%) used an operational definition, and most specified types of skills lost (n?=?147, 93.6%). Age of onset was specified in 67.5% (n?=?106), and duration was specified in 34.4% (n?=?54). Measures designed to specifically assess developmental regression were infrequently used (n?=?5, 3.2%). We concluded that developmental regression is inconsistently defined and measured. A consistent approach is vital to ensure that all children are identified as early as possible. This will allow timely diagnostic discovery, enhance research rigor, and promote the collaboration that is needed to advance our understanding of causal mechanisms and effective interventions for affected children and their families. En ligne : https://doi.org/10.1002/aur.70325 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] Defining and Measuring Developmental Regression During Childhood: A Scoping Review [texte imprimé] / Kirsten FURLEY, Auteur ; Jenny FAIRTHORNE, Auteur ; Vishnu Priya Mohanakumar SINDHU, Auteur ; Katrina WILLIAMS, Auteur ; Amanda BRIGNELL, Auteur . - p. e70325. Langues : Anglais (eng) in Autism Research > 19-9 (September 2026) . - p. e70325 Mots-clés : child development disorders  definition  developmental disabilities  developmental regression  neurodevelopmental disorders  pervasive Index. décimale : PER Périodiques Résumé : ABSTRACT Developmental regression during childhood is inconsistently defined and measured, resulting in delayed diagnostic discovery and intervention. This study aimed to examine published definitions and measures for developmental regression. A comprehensive search strategy was applied to Medline, Embase, Cochrane, and PsycINFO databases. Reviewers independently screened relevant studies according to the Preferred Reporting Items for Systematic reviews. The number and percentages of definition use, their primary features, and measures were reported. Of 19,099 potential publications, 157 were included. Thematic analysis identified four condition groups: Neurodevelopmental disorders (n?=?118); Progressive neurodegenerative conditions (n?=?17); Developmental epileptic encephalopathies (n?=?8); and Genetic conditions (n?=?14). Most studies (n?=?124, 79.0%) used an operational definition, and most specified types of skills lost (n?=?147, 93.6%). Age of onset was specified in 67.5% (n?=?106), and duration was specified in 34.4% (n?=?54). Measures designed to specifically assess developmental regression were infrequently used (n?=?5, 3.2%). We concluded that developmental regression is inconsistently defined and measured. A consistent approach is vital to ensure that all children are identified as early as possible. This will allow timely diagnostic discovery, enhance research rigor, and promote the collaboration that is needed to advance our understanding of causal mechanisms and effective interventions for affected children and their families. En ligne : https://doi.org/10.1002/aur.70325 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592

Oculomotor Function in Children and Adolescents with Autism, ADHD or Co-occurring Autism and ADHD / Elana J. FORBES in Journal of Autism and Developmental Disorders, 56-6 (June 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-6 (June 2026) . - p.2391-2407 Titre : Oculomotor Function in Children and Adolescents with Autism, ADHD or Co-occurring Autism and ADHD Type de document : texte imprimé Auteurs : Elana J. FORBES, Auteur ; Jeggan TIEGO, Auteur ; Joshua LANGMEAD, Auteur ; Kathryn E. UNRUH, Auteur ; Matthew W. MOSCONI, Auteur ; Amy FINLAY, Auteur ; Kathryn KALLADY, Auteur ; Lydia MACLACHLAN, Auteur ; Mia MOSES, Auteur ; Kai CAPPEL, Auteur ; Rachael KNOTT, Auteur ; Tracey CHAU, Auteur ; Vishnu Priya Mohanakumar SINDHU, Auteur ; Alessio BELLATO, Auteur ; Madeleine J. GROOM, Auteur ; Rebecca KERESTES, Auteur ; Mark A. BELLGROVE, Auteur ; Beth P. JOHNSON, Auteur Article en page(s) : p.2391-2407 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Oculomotor characteristics, including accuracy, timing, and sensorimotor processing, are considered sensitive intermediate phenotypes for understanding the etiology of neurodevelopmental conditions, such as autism and ADHD. Oculomotor characteristics have predominantly been studied separately in autism and ADHD. Despite the high rates of co-occurrence between these conditions, only one study has investigated oculomotor processes among those with co-occurring autism + ADHD. Four hundred and five (n = 405; 226 males) Australian children and adolescents aged 4 to 18 years (M = 9.64 years; SD = 3.20 years) with ADHD (n = 64), autism (n = 66), autism + ADHD (n = 146), or neurotypical individuals (n = 129) were compared across four different oculomotor tasks: visually guided saccade, anti-saccade, sinusoidal pursuit and step-ramp pursuit. Confirmatory analyses were conducted using separate datasets acquired from the University of Nottingham UK (n = 17 autism, n = 22 ADHD, n = 32 autism + ADHD, n = 30 neurotypical) and University of Kansas USA (n = 29 autism, n = 41 neurotypical). Linear mixed effect models controlling for sex, age and family revealed that children and adolescents with autism + ADHD exhibited increased variability in the accuracy of the final saccadic eye position compared to neurotypical children and adolescents. Autistic children and adolescents demonstrated a greater number of catch-up saccades during step-ramp pursuit compared to neurotypical children and adolescents. These findings suggest that select differences in saccadic precision are unique to autistic individuals with co-occurring ADHD, indicating that measuring basic sensorimotor processes may be useful for parsing neurodevelopment and clinical heterogeneity in autism. En ligne : https://doi.org/10.1007/s10803-024-06718-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=588 [article] Oculomotor Function in Children and Adolescents with Autism, ADHD or Co-occurring Autism and ADHD [texte imprimé] / Elana J. FORBES, Auteur ; Jeggan TIEGO, Auteur ; Joshua LANGMEAD, Auteur ; Kathryn E. UNRUH, Auteur ; Matthew W. MOSCONI, Auteur ; Amy FINLAY, Auteur ; Kathryn KALLADY, Auteur ; Lydia MACLACHLAN, Auteur ; Mia MOSES, Auteur ; Kai CAPPEL, Auteur ; Rachael KNOTT, Auteur ; Tracey CHAU, Auteur ; Vishnu Priya Mohanakumar SINDHU, Auteur ; Alessio BELLATO, Auteur ; Madeleine J. GROOM, Auteur ; Rebecca KERESTES, Auteur ; Mark A. BELLGROVE, Auteur ; Beth P. JOHNSON, Auteur . - p.2391-2407. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-6 (June 2026) . - p.2391-2407 Index. décimale : PER Périodiques Résumé : Oculomotor characteristics, including accuracy, timing, and sensorimotor processing, are considered sensitive intermediate phenotypes for understanding the etiology of neurodevelopmental conditions, such as autism and ADHD. Oculomotor characteristics have predominantly been studied separately in autism and ADHD. Despite the high rates of co-occurrence between these conditions, only one study has investigated oculomotor processes among those with co-occurring autism + ADHD. Four hundred and five (n = 405; 226 males) Australian children and adolescents aged 4 to 18 years (M = 9.64 years; SD = 3.20 years) with ADHD (n = 64), autism (n = 66), autism + ADHD (n = 146), or neurotypical individuals (n = 129) were compared across four different oculomotor tasks: visually guided saccade, anti-saccade, sinusoidal pursuit and step-ramp pursuit. Confirmatory analyses were conducted using separate datasets acquired from the University of Nottingham UK (n = 17 autism, n = 22 ADHD, n = 32 autism + ADHD, n = 30 neurotypical) and University of Kansas USA (n = 29 autism, n = 41 neurotypical). Linear mixed effect models controlling for sex, age and family revealed that children and adolescents with autism + ADHD exhibited increased variability in the accuracy of the final saccadic eye position compared to neurotypical children and adolescents. Autistic children and adolescents demonstrated a greater number of catch-up saccades during step-ramp pursuit compared to neurotypical children and adolescents. These findings suggest that select differences in saccadic precision are unique to autistic individuals with co-occurring ADHD, indicating that measuring basic sensorimotor processes may be useful for parsing neurodevelopment and clinical heterogeneity in autism. En ligne : https://doi.org/10.1007/s10803-024-06718-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=588

---

1 (1 - 2 / 2) Par page : 25 50 100 200