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Auteur R. EDMONDSON-PRETZEL |
Documents disponibles écrits par cet auteur (1)
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Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development / Lisa D. WIGGINS in Journal of Autism and Developmental Disorders, 47-11 (November 2017)
[article]
Titre : Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development Type de document : Texte imprimé et/ou numérique Auteurs : Lisa D. WIGGINS, Auteur ; L. H. TIAN, Auteur ; S. E. LEVY, Auteur ; C. RICE, Auteur ; L. C. LEE, Auteur ; Laura A. SCHIEVE, Auteur ; J. PANDEY, Auteur ; J. DANIELS, Auteur ; Lisa BLASKEY, Auteur ; S. HEPBURN, Auteur ; R. LANDA, Auteur ; R. EDMONDSON-PRETZEL, Auteur ; W. THOMPSON, Auteur Article en page(s) : p.3634-3645 Langues : Anglais (eng) Mots-clés : Autism Autism spectrum disorder Characterization Phenotypes Subgroups Index. décimale : PER Périodiques Résumé : The objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: mild language delay with cognitive rigidity, mild language and motor delay with dysregulation, general developmental delay, and significant developmental delay with repetitive motor behaviors. We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed. En ligne : http://dx.doi.org/10.1007/s10803-017-3280-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325
in Journal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3634-3645[article] Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development [Texte imprimé et/ou numérique] / Lisa D. WIGGINS, Auteur ; L. H. TIAN, Auteur ; S. E. LEVY, Auteur ; C. RICE, Auteur ; L. C. LEE, Auteur ; Laura A. SCHIEVE, Auteur ; J. PANDEY, Auteur ; J. DANIELS, Auteur ; Lisa BLASKEY, Auteur ; S. HEPBURN, Auteur ; R. LANDA, Auteur ; R. EDMONDSON-PRETZEL, Auteur ; W. THOMPSON, Auteur . - p.3634-3645.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-11 (November 2017) . - p.3634-3645
Mots-clés : Autism Autism spectrum disorder Characterization Phenotypes Subgroups Index. décimale : PER Périodiques Résumé : The objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: mild language delay with cognitive rigidity, mild language and motor delay with dysregulation, general developmental delay, and significant developmental delay with repetitive motor behaviors. We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed. En ligne : http://dx.doi.org/10.1007/s10803-017-3280-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=325