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Auteur I. NOENS |
Documents disponibles écrits par cet auteur (11)



Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study / Bart BOETS in Molecular Autism, 9 (2018)
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Titre : Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study Type de document : Texte imprimé et/ou numérique Auteurs : Bart BOETS, Auteur ; L. VAN EYLEN, Auteur ; K. SITEK, Auteur ; P. MOORS, Auteur ; I. NOENS, Auteur ; J. STEYAERT, Auteur ; S. SUNAERT, Auteur ; J. WAGEMANS, Auteur Article en page(s) : 10p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Diffusion-weighted imaging Inferior longitudinal fasciculus Structural connectivity Visual processing Index. décimale : PER Périodiques Résumé : Background: One of the most reported neural features of autism spectrum disorder (ASD) is the alteration of multiple long-range white matter fiber tracts, as assessed by diffusion-weighted imaging and indexed by reduced fractional anisotropy (FA). Recent methodological advances, however, have shown that this same pattern of reduced FA may be an artifact resulting from excessive head motion and poorer data quality and that aberrant structural connectivity in children with ASD is confined to the right inferior longitudinal fasciculus (ILF). This study aimed at replicating the observation of reduced FA along the right ILF in ASD, while controlling for group differences in head motion and data quality. In addition, we explored associations between reduced FA in the right ILF and quantitative ASD characteristics, and the involvement of the right ILF in visual processing, which is known to be altered in ASD. Method: Global probabilistic tractography was performed on diffusion-weighted imaging data of 17 adolescent boys with ASD and 17 typically developing boys, matched for age, performance IQ, handedness, and data quality. Four tasks were administered to measure various aspects of visual information processing, together with questionnaires assessing ASD characteristics. Group differences were examined and the neural data were integrated with previously published findings using Bayesian statistics to quantify evidence for replication and to pool data and thus increase statistical power. (Partial) correlations were calculated to investigate associations between measures. Results: The ASD group showed consistently reduced FA only in the right ILF and slower performance on the visual search task. Bayesian statistics pooling data across studies confirmed that group differences in FA were confined to the right ILF only, with the evidence for altered FA in the left ILF being indecisive. Lower FA in the right ILF tended to covary with slower visual search and a more fragmented part-oriented processing style. Individual differences in FA of the right ILF were not reliably associated with the severity of ASD traits after controlling for clinical status. Conclusion: Our findings support the growing evidence for reduced FA along a specific fiber tract in ASD, the right ILF. En ligne : http://dx.doi.org/10.1186/s13229-018-0188-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354
in Molecular Autism > 9 (2018) . - 10p.[article] Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study [Texte imprimé et/ou numérique] / Bart BOETS, Auteur ; L. VAN EYLEN, Auteur ; K. SITEK, Auteur ; P. MOORS, Auteur ; I. NOENS, Auteur ; J. STEYAERT, Auteur ; S. SUNAERT, Auteur ; J. WAGEMANS, Auteur . - 10p.
Langues : Anglais (eng)
in Molecular Autism > 9 (2018) . - 10p.
Mots-clés : Autism spectrum disorder Diffusion-weighted imaging Inferior longitudinal fasciculus Structural connectivity Visual processing Index. décimale : PER Périodiques Résumé : Background: One of the most reported neural features of autism spectrum disorder (ASD) is the alteration of multiple long-range white matter fiber tracts, as assessed by diffusion-weighted imaging and indexed by reduced fractional anisotropy (FA). Recent methodological advances, however, have shown that this same pattern of reduced FA may be an artifact resulting from excessive head motion and poorer data quality and that aberrant structural connectivity in children with ASD is confined to the right inferior longitudinal fasciculus (ILF). This study aimed at replicating the observation of reduced FA along the right ILF in ASD, while controlling for group differences in head motion and data quality. In addition, we explored associations between reduced FA in the right ILF and quantitative ASD characteristics, and the involvement of the right ILF in visual processing, which is known to be altered in ASD. Method: Global probabilistic tractography was performed on diffusion-weighted imaging data of 17 adolescent boys with ASD and 17 typically developing boys, matched for age, performance IQ, handedness, and data quality. Four tasks were administered to measure various aspects of visual information processing, together with questionnaires assessing ASD characteristics. Group differences were examined and the neural data were integrated with previously published findings using Bayesian statistics to quantify evidence for replication and to pool data and thus increase statistical power. (Partial) correlations were calculated to investigate associations between measures. Results: The ASD group showed consistently reduced FA only in the right ILF and slower performance on the visual search task. Bayesian statistics pooling data across studies confirmed that group differences in FA were confined to the right ILF only, with the evidence for altered FA in the left ILF being indecisive. Lower FA in the right ILF tended to covary with slower visual search and a more fragmented part-oriented processing style. Individual differences in FA of the right ILF were not reliably associated with the severity of ASD traits after controlling for clinical status. Conclusion: Our findings support the growing evidence for reduced FA along a specific fiber tract in ASD, the right ILF. En ligne : http://dx.doi.org/10.1186/s13229-018-0188-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354 Change detection of meaningful objects in real-world scenes in adolescents with and without autism spectrum disorder / S. VANMARCKE in Autism, 22-6 (August 2018)
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Titre : Change detection of meaningful objects in real-world scenes in adolescents with and without autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : S. VANMARCKE, Auteur ; I. NOENS, Auteur ; J. STEYAERT, Auteur ; J. WAGEMANS, Auteur Article en page(s) : p.728-739 Langues : Anglais (eng) Mots-clés : autism spectrum disorders change blindness local-global processing vision research Index. décimale : PER Périodiques Résumé : Previous research suggested that adolescents with autism spectrum disorder are better than typically developing children in detecting local, non-social details within complex visual scenes. To better understand these differences, we used the image database by Sareen et al., containing the size and on-screen location information of all changes in the images, in a change blindness paradigm. In this task, an original and a modified real-world scene, separated by a gray blank, alternate repeatedly until observers detect the change. Our results indicated that participants with and without autism spectrum disorder performed similarly when scenes were presented upright, but that only the performance of the typically developing adolescents became worse in the inverted scene condition. In this condition, the correlation between performance and both image difficulty and change predictability was significantly weaker in autism spectrum disorder than in typically developing participants. We suggest that these findings result from a more locally biased search strategy in people with autism spectrum disorder, compared to typically developing participants, in tasks in which the rapid processing of global information does not help to improve change detection performance. Finally, although we found change location, change size, and age to influence participant performance, none of these was directly linked to the observed group-level differences. En ligne : http://dx.doi.org/10.1177/1362361317702559 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=366
in Autism > 22-6 (August 2018) . - p.728-739[article] Change detection of meaningful objects in real-world scenes in adolescents with and without autism spectrum disorder [Texte imprimé et/ou numérique] / S. VANMARCKE, Auteur ; I. NOENS, Auteur ; J. STEYAERT, Auteur ; J. WAGEMANS, Auteur . - p.728-739.
Langues : Anglais (eng)
in Autism > 22-6 (August 2018) . - p.728-739
Mots-clés : autism spectrum disorders change blindness local-global processing vision research Index. décimale : PER Périodiques Résumé : Previous research suggested that adolescents with autism spectrum disorder are better than typically developing children in detecting local, non-social details within complex visual scenes. To better understand these differences, we used the image database by Sareen et al., containing the size and on-screen location information of all changes in the images, in a change blindness paradigm. In this task, an original and a modified real-world scene, separated by a gray blank, alternate repeatedly until observers detect the change. Our results indicated that participants with and without autism spectrum disorder performed similarly when scenes were presented upright, but that only the performance of the typically developing adolescents became worse in the inverted scene condition. In this condition, the correlation between performance and both image difficulty and change predictability was significantly weaker in autism spectrum disorder than in typically developing participants. We suggest that these findings result from a more locally biased search strategy in people with autism spectrum disorder, compared to typically developing participants, in tasks in which the rapid processing of global information does not help to improve change detection performance. Finally, although we found change location, change size, and age to influence participant performance, none of these was directly linked to the observed group-level differences. En ligne : http://dx.doi.org/10.1177/1362361317702559 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=366 Correction to: Describing the Profile of Diagnostic Features in Autistic Adults Using an Abbreviated Version of the Diagnostic Interview for Social and Communication Disorders (DISCO-Abbreviated) / Sarah J. CARRINGTON in Journal of Autism and Developmental Disorders, 51-6 (June 2021)
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Titre : Correction to: Describing the Profile of Diagnostic Features in Autistic Adults Using an Abbreviated Version of the Diagnostic Interview for Social and Communication Disorders (DISCO-Abbreviated) Type de document : Texte imprimé et/ou numérique Auteurs : Sarah J. CARRINGTON, Auteur ; Sarah L. BARRETT, Auteur ; U. SIVAGAMASUNDARI, Auteur ; C. FRETWELL, Auteur ; I. NOENS, Auteur ; J. MALJAARS, Auteur ; S. R. LEEKAM, Auteur Article en page(s) : p.1880-1882 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04664-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452
in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.1880-1882[article] Correction to: Describing the Profile of Diagnostic Features in Autistic Adults Using an Abbreviated Version of the Diagnostic Interview for Social and Communication Disorders (DISCO-Abbreviated) [Texte imprimé et/ou numérique] / Sarah J. CARRINGTON, Auteur ; Sarah L. BARRETT, Auteur ; U. SIVAGAMASUNDARI, Auteur ; C. FRETWELL, Auteur ; I. NOENS, Auteur ; J. MALJAARS, Auteur ; S. R. LEEKAM, Auteur . - p.1880-1882.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.1880-1882
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04664-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 Corrigendum to “DSM-5 Autism Spectrum Disorder: In search of essential behaviours for diagnosis” [Res. Autism Spectr. Disord. 8 (2014) (6) 701–715] / Sarah J. CARRINGTON in Research in Autism Spectrum Disorders, 78 (October 2020)
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Titre : Corrigendum to “DSM-5 Autism Spectrum Disorder: In search of essential behaviours for diagnosis” [Res. Autism Spectr. Disord. 8 (2014) (6) 701–715] Type de document : Texte imprimé et/ou numérique Auteurs : Sarah J. CARRINGTON, Auteur ; R. G. KENT, Auteur ; J. MALJAARS, Auteur ; A. LE COUTEUR, Auteur ; J. GOULD, Auteur ; L. WING, Auteur ; I. NOENS, Auteur ; I. VAN BERCKELAR-ONNES, Auteur ; S. R. LEEKAM, Auteur Article en page(s) : 101649 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1016/j.rasd.2020.101649 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433
in Research in Autism Spectrum Disorders > 78 (October 2020) . - 101649[article] Corrigendum to “DSM-5 Autism Spectrum Disorder: In search of essential behaviours for diagnosis” [Res. Autism Spectr. Disord. 8 (2014) (6) 701–715] [Texte imprimé et/ou numérique] / Sarah J. CARRINGTON, Auteur ; R. G. KENT, Auteur ; J. MALJAARS, Auteur ; A. LE COUTEUR, Auteur ; J. GOULD, Auteur ; L. WING, Auteur ; I. NOENS, Auteur ; I. VAN BERCKELAR-ONNES, Auteur ; S. R. LEEKAM, Auteur . - 101649.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 78 (October 2020) . - 101649
Index. décimale : PER Périodiques En ligne : https://doi.org/10.1016/j.rasd.2020.101649 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 Describing the Profile of Diagnostic Features in Autistic Adults Using an Abbreviated Version of the Diagnostic Interview for Social and Communication Disorders (DISCO-Abbreviated) / Sarah J. CARRINGTON in Journal of Autism and Developmental Disorders, 49-12 (December 2019)
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[article]
Titre : Describing the Profile of Diagnostic Features in Autistic Adults Using an Abbreviated Version of the Diagnostic Interview for Social and Communication Disorders (DISCO-Abbreviated) Type de document : Texte imprimé et/ou numérique Auteurs : Sarah J. CARRINGTON, Auteur ; Sarah L. BARRETT, Auteur ; U. SIVAGAMASUNDARI, Auteur ; C. FRETWELL, Auteur ; I. NOENS, Auteur ; J. MALJAARS, Auteur ; S. R. LEEKAM, Auteur Article en page(s) : p.5036-5046 Langues : Anglais (eng) Mots-clés : Adult Autism spectrum disorder Dsm-5 Diagnosis Index. décimale : PER Périodiques Résumé : The rate of diagnosis of autism in adults has increased over recent years; however, the profile of behaviours in these individuals is less understood than the profile seen in those diagnosed in childhood. Better understanding of this profile will be essential to identify and remove potential barriers to diagnosis. Using an abbreviated form of the Diagnostic Interview for Social and Communication Disorders, comparisons were drawn between the profile of a sample of able adults diagnosed in adulthood and the profile of a sample of able children. Results revealed both similarities and differences. A relative strength in non-verbal communication highlighted a potential barrier to diagnosis according to DSM-5 criteria for the adult sample, which may also have prevented them from being diagnosed as children. En ligne : http://dx.doi.org/10.1007/s10803-019-04214-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=411
in Journal of Autism and Developmental Disorders > 49-12 (December 2019) . - p.5036-5046[article] Describing the Profile of Diagnostic Features in Autistic Adults Using an Abbreviated Version of the Diagnostic Interview for Social and Communication Disorders (DISCO-Abbreviated) [Texte imprimé et/ou numérique] / Sarah J. CARRINGTON, Auteur ; Sarah L. BARRETT, Auteur ; U. SIVAGAMASUNDARI, Auteur ; C. FRETWELL, Auteur ; I. NOENS, Auteur ; J. MALJAARS, Auteur ; S. R. LEEKAM, Auteur . - p.5036-5046.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 49-12 (December 2019) . - p.5036-5046
Mots-clés : Adult Autism spectrum disorder Dsm-5 Diagnosis Index. décimale : PER Périodiques Résumé : The rate of diagnosis of autism in adults has increased over recent years; however, the profile of behaviours in these individuals is less understood than the profile seen in those diagnosed in childhood. Better understanding of this profile will be essential to identify and remove potential barriers to diagnosis. Using an abbreviated form of the Diagnostic Interview for Social and Communication Disorders, comparisons were drawn between the profile of a sample of able adults diagnosed in adulthood and the profile of a sample of able children. Results revealed both similarities and differences. A relative strength in non-verbal communication highlighted a potential barrier to diagnosis according to DSM-5 criteria for the adult sample, which may also have prevented them from being diagnosed as children. En ligne : http://dx.doi.org/10.1007/s10803-019-04214-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=411 How do Parents Manage Irritability, Challenging Behaviour, Non-Compliance and Anxiety in Children with Autism Spectrum Disorders? A Meta-Synthesis / E. O'NIONS in Journal of Autism and Developmental Disorders, 48-4 (April 2018)
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PermalinkLocal and Global Visual Processing in Autism Spectrum Disorders: Influence of Task and Sample Characteristics and Relation to Symptom Severity / L. VAN EYLEN in Journal of Autism and Developmental Disorders, 48-4 (April 2018)
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PermalinkMultiple Object Tracking Reveals Object-Based Grouping Interference in Children with ASD / R. VAN DER HALLEN in Journal of Autism and Developmental Disorders, 48-4 (April 2018)
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PermalinkParenting adolescents with ASD: A multimethod study / L. VAN ESCH in Autism Research, 11-7 (July 2018)
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PermalinkParenting Behavior in Mothers of Preschool Children with ASD: Development of a Self-Report Questionnaire / G. LAMBRECHTS in Autism Research and Treatment, 2015 (2015)
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PermalinkStructural and contextual priors affect visual search in children with and without autism / S. VAN DE CRUYS in Autism Research, 14-7 (July 2021)
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