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Détail de l'auteur
Auteur Samantha N. SALLIE |
Documents disponibles écrits par cet auteur (1)
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Resilient functioning is associated with altered structural brain network topology in adolescents exposed to childhood adversity / Edward T. BULLMORE ; Raymond J. DOLAN ; Peter FONAGY ; Nadia GONZÁLEZ-GARCÍA ; Ian GOODYER ; Peter B. JONES ; Sol LIM ; Laura MORENO-LÓPEZ ; Rafael ROMERO-GARCIA ; Samantha N. SALLIE ; Maximilian SCHEUPLEIN ; Franti?ek VÁ?A ; Kirstie J. WHITAKER ; Anne-Laura VAN HARMELEN in Development and Psychopathology, 35-5 (December 2023)
[article]
Titre : Resilient functioning is associated with altered structural brain network topology in adolescents exposed to childhood adversity Type de document : Texte imprimé et/ou numérique Auteurs : Edward T. BULLMORE, Auteur ; Raymond J. DOLAN, Auteur ; Peter FONAGY, Auteur ; Nadia GONZÁLEZ-GARCÍA, Auteur ; Ian GOODYER, Auteur ; Peter B. JONES, Auteur ; Sol LIM, Auteur ; Laura MORENO-LÓPEZ, Auteur ; Rafael ROMERO-GARCIA, Auteur ; Samantha N. SALLIE, Auteur ; Maximilian SCHEUPLEIN, Auteur ; Franti?ek VÁ?A, Auteur ; Kirstie J. WHITAKER, Auteur ; Anne-Laura VAN HARMELEN, Auteur Article en page(s) : p.2253-2263 Mots-clés : adolescence brain networks childhood adversity resilience structural covariance Index. décimale : PER Périodiques Résumé : Childhood adversity is one of the strongest predictors of adolescent mental illness. Therefore, it is critical that the mechanisms that aid resilient functioning in individuals exposed to childhood adversity are better understood. Here, we examined whether resilient functioning was related to structural brain network topology. We quantified resilient functioning at the individual level as psychosocial functioning adjusted for the severity of childhood adversity in a large sample of adolescents (N = 2406, aged 14?24). Next, we examined nodal degree (the number of connections that brain regions have in a network) using brain-wide cortical thickness measures in a representative subset (N = 275) using a sliding window approach. We found that higher resilient functioning was associated with lower nodal degree of multiple regions including the dorsolateral prefrontal cortex, the medial prefrontal cortex, and the posterior superior temporal sulcus (z > 1.645). During adolescence, decreases in nodal degree are thought to reflect a normative developmental process that is part of the extensive remodeling of structural brain network topology. Prior findings in this sample showed that decreased nodal degree was associated with age, as such our findings of negative associations between nodal degree and resilient functioning may therefore potentially resemble a more mature structural network configuration in individuals with higher resilient functioning. En ligne : https://dx.doi.org/10.1017/S0954579423000901 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519
in Development and Psychopathology > 35-5 (December 2023) . - p.2253-2263[article] Resilient functioning is associated with altered structural brain network topology in adolescents exposed to childhood adversity [Texte imprimé et/ou numérique] / Edward T. BULLMORE, Auteur ; Raymond J. DOLAN, Auteur ; Peter FONAGY, Auteur ; Nadia GONZÁLEZ-GARCÍA, Auteur ; Ian GOODYER, Auteur ; Peter B. JONES, Auteur ; Sol LIM, Auteur ; Laura MORENO-LÓPEZ, Auteur ; Rafael ROMERO-GARCIA, Auteur ; Samantha N. SALLIE, Auteur ; Maximilian SCHEUPLEIN, Auteur ; Franti?ek VÁ?A, Auteur ; Kirstie J. WHITAKER, Auteur ; Anne-Laura VAN HARMELEN, Auteur . - p.2253-2263.
in Development and Psychopathology > 35-5 (December 2023) . - p.2253-2263
Mots-clés : adolescence brain networks childhood adversity resilience structural covariance Index. décimale : PER Périodiques Résumé : Childhood adversity is one of the strongest predictors of adolescent mental illness. Therefore, it is critical that the mechanisms that aid resilient functioning in individuals exposed to childhood adversity are better understood. Here, we examined whether resilient functioning was related to structural brain network topology. We quantified resilient functioning at the individual level as psychosocial functioning adjusted for the severity of childhood adversity in a large sample of adolescents (N = 2406, aged 14?24). Next, we examined nodal degree (the number of connections that brain regions have in a network) using brain-wide cortical thickness measures in a representative subset (N = 275) using a sliding window approach. We found that higher resilient functioning was associated with lower nodal degree of multiple regions including the dorsolateral prefrontal cortex, the medial prefrontal cortex, and the posterior superior temporal sulcus (z > 1.645). During adolescence, decreases in nodal degree are thought to reflect a normative developmental process that is part of the extensive remodeling of structural brain network topology. Prior findings in this sample showed that decreased nodal degree was associated with age, as such our findings of negative associations between nodal degree and resilient functioning may therefore potentially resemble a more mature structural network configuration in individuals with higher resilient functioning. En ligne : https://dx.doi.org/10.1017/S0954579423000901 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519