Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Stan VAN UUM |
Documents disponibles écrits par cet auteur (1)
Faire une suggestion Affiner la recherche
Risk and resilience in Syrian refugee children: A multisystem analysis / Elie G. KARAM ; Andrew K. MAY ; Michael PLUESS ; Michael J. RIEDER ; Demelza SMEETH ; Stan VAN UUM in Development and Psychopathology, 35-5 (December 2023)
[article]
Titre : Risk and resilience in Syrian refugee children: A multisystem analysis Type de document : Texte imprimé et/ou numérique Auteurs : Elie G. KARAM, Auteur ; Andrew K. MAY, Auteur ; Michael PLUESS, Auteur ; Michael J. RIEDER, Auteur ; Demelza SMEETH, Auteur ; Stan VAN UUM, Auteur Article en page(s) : p.2275-2287 Mots-clés : hair cortisol mental health polygenic scores refugee children resilience Index. décimale : PER Périodiques Résumé : Refugee children are often exposed to substantial trauma, placing them at increased risk for mental illness. However, this risk can be mitigated by a capacity for resilience, conferred from multiple ecological systems (e.g., family, community), including at an individual biological level. We examined the ability of hair cortisol concentrations and polygenic scores for mental health to predict risk and resilience in a sample of Syrian refugee children (n = 1359). Children were categorized as either at-risk or resilient depending on clinical thresholds for posttraumatic stress disorder, depression, and externalizing behavior problems. Logistic regression was used to examine main and interacting effects while controlling for covariates. Elevated hair cortisol concentrations were significantly associated with reduced resilience (odds ratio (OR)=0.58, 95%CI [0.40, 0.83]) while controlling for levels of war exposure. Polygenic scores for depression, self-harm, and neuroticism were not found to have any significant main effects. However, a significant interaction emerged between hair cortisol and polygenic scores for depression (OR=0.04, 95%CI [0.003 0.47]), suggesting that children predisposed to depression were more at risk for mental health problems when hair cortisol concentrations were high. Our results suggest that biomarkers (separately and in combination) might support early identification of refugee children at risk for mental health problems. En ligne : https://dx.doi.org/10.1017/S0954579423000433 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519
in Development and Psychopathology > 35-5 (December 2023) . - p.2275-2287[article] Risk and resilience in Syrian refugee children: A multisystem analysis [Texte imprimé et/ou numérique] / Elie G. KARAM, Auteur ; Andrew K. MAY, Auteur ; Michael PLUESS, Auteur ; Michael J. RIEDER, Auteur ; Demelza SMEETH, Auteur ; Stan VAN UUM, Auteur . - p.2275-2287.
in Development and Psychopathology > 35-5 (December 2023) . - p.2275-2287
Mots-clés : hair cortisol mental health polygenic scores refugee children resilience Index. décimale : PER Périodiques Résumé : Refugee children are often exposed to substantial trauma, placing them at increased risk for mental illness. However, this risk can be mitigated by a capacity for resilience, conferred from multiple ecological systems (e.g., family, community), including at an individual biological level. We examined the ability of hair cortisol concentrations and polygenic scores for mental health to predict risk and resilience in a sample of Syrian refugee children (n = 1359). Children were categorized as either at-risk or resilient depending on clinical thresholds for posttraumatic stress disorder, depression, and externalizing behavior problems. Logistic regression was used to examine main and interacting effects while controlling for covariates. Elevated hair cortisol concentrations were significantly associated with reduced resilience (odds ratio (OR)=0.58, 95%CI [0.40, 0.83]) while controlling for levels of war exposure. Polygenic scores for depression, self-harm, and neuroticism were not found to have any significant main effects. However, a significant interaction emerged between hair cortisol and polygenic scores for depression (OR=0.04, 95%CI [0.003 0.47]), suggesting that children predisposed to depression were more at risk for mental health problems when hair cortisol concentrations were high. Our results suggest that biomarkers (separately and in combination) might support early identification of refugee children at risk for mental health problems. En ligne : https://dx.doi.org/10.1017/S0954579423000433 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519