4 recherche sur le mot-clé 'hair cortisol'

Associations between developmental trajectories of peer victimization, hair cortisol, and depressive symptoms: a longitudinal study / Isabelle OUELLET-MORIN in Journal of Child Psychology and Psychiatry, 62-1 (January 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.19-27 Titre : Associations between developmental trajectories of peer victimization, hair cortisol, and depressive symptoms: a longitudinal study Type de document : Texte imprimé et/ou numérique Auteurs : Isabelle OUELLET-MORIN, Auteur ; Christina CANTAVE, Auteur ; Stéphane PAQUIN, Auteur ; Marie-Claude GEOFFROY, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Richard TREMBLAY, Auteur ; Michel BOIVIN, Auteur ; Sonia LUPIEN, Auteur ; Sylvana M. CÔTÉ, Auteur Article en page(s) : p.19-27 Langues : Anglais (eng) Mots-clés : HPA axis  Peer victimization  depression  hair cortisol  nonlinear models Index. décimale : PER Périodiques Résumé : BACKGROUND: Peer victimization has been associated with long-lasting risks for mental health. Prior research suggests that stress-related systems underlying adaptation to changing environments may be at play. To date, inconsistent findings have been reported for the hypothalamic-pituitary-adrenal (HPA) axis, and its end product cortisol. This study tested whether peer victimization was associated with hair cortisol concentrations (HCC), and whether this association varied according to sex, timing, and changes in exposure. We also examined whether peer victimization differentially predicted depressive symptoms according to HCC. METHODS: The sample comprised 556 adolescents (42.0%; 231 males) who provided hair for cortisol measurement at 17 years of age. Peer victimization was reported at seven occasions between the ages of 6 and 15 years. RESULTS: Peer victimization was nonlinearly associated with HCC for boys only, whereas changes in peer victimization were related to HCC for boys and girls. Peer victimization predicted more depressive symptoms for all participants, except those with lower HCC. CONCLUSIONS: Our findings provide further support for persistent dysregulation of the HPA axis following exposure to chronic adversity, of which the expression may change according to sex and the severity of victimization. En ligne : http://dx.doi.org/10.1111/jcpp.13228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435 [article] Associations between developmental trajectories of peer victimization, hair cortisol, and depressive symptoms: a longitudinal study [Texte imprimé et/ou numérique] / Isabelle OUELLET-MORIN, Auteur ; Christina CANTAVE, Auteur ; Stéphane PAQUIN, Auteur ; Marie-Claude GEOFFROY, Auteur ; Mara BRENDGEN, Auteur ; Frank VITARO, Auteur ; Richard TREMBLAY, Auteur ; Michel BOIVIN, Auteur ; Sonia LUPIEN, Auteur ; Sylvana M. CÔTÉ, Auteur . - p.19-27. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.19-27 Mots-clés : HPA axis  Peer victimization  depression  hair cortisol  nonlinear models Index. décimale : PER Périodiques Résumé : BACKGROUND: Peer victimization has been associated with long-lasting risks for mental health. Prior research suggests that stress-related systems underlying adaptation to changing environments may be at play. To date, inconsistent findings have been reported for the hypothalamic-pituitary-adrenal (HPA) axis, and its end product cortisol. This study tested whether peer victimization was associated with hair cortisol concentrations (HCC), and whether this association varied according to sex, timing, and changes in exposure. We also examined whether peer victimization differentially predicted depressive symptoms according to HCC. METHODS: The sample comprised 556 adolescents (42.0%; 231 males) who provided hair for cortisol measurement at 17 years of age. Peer victimization was reported at seven occasions between the ages of 6 and 15 years. RESULTS: Peer victimization was nonlinearly associated with HCC for boys only, whereas changes in peer victimization were related to HCC for boys and girls. Peer victimization predicted more depressive symptoms for all participants, except those with lower HCC. CONCLUSIONS: Our findings provide further support for persistent dysregulation of the HPA axis following exposure to chronic adversity, of which the expression may change according to sex and the severity of victimization. En ligne : http://dx.doi.org/10.1111/jcpp.13228 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435

Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence / Lars O. WHITE in Journal of Child Psychology and Psychiatry, 58-9 (September 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-9 (September 2017) . - p.998-1007 Titre : Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence Type de document : Texte imprimé et/ou numérique Auteurs : Lars O. WHITE, Auteur ; Marcus ISING, Auteur ; Kai VON KLITZING, Auteur ; Susan SIERAU, Auteur ; Andrea MICHEL, Auteur ; Annette M. KLEIN, Auteur ; Anna ANDREAS, Auteur ; Jan KEIL, Auteur ; Leonhard QUINTERO, Auteur ; Bertram MÜLLER-MYHSOK, Auteur ; Manfred UHR, Auteur ; Ruth GAUSCHE, Auteur ; Jody T. MANLY, Auteur ; Michael J. CROWLEY, Auteur ; Clemens KIRSCHBAUM, Auteur ; Tobias STALDER, Auteur Article en page(s) : p.998-1007 Langues : Anglais (eng) Mots-clés : Hair cortisol  maltreatment  neglect  externalizing symptoms Index. décimale : PER Périodiques Résumé : Background The enduring impact of childhood maltreatment on biological systems and ensuing psychopathology remains incompletely understood. Long-term effects of stress may be reflected in cumulative cortisol secretion over several months, which is now quantifiable via hair cortisol concentrations (HCC). We conducted a first comprehensive investigation utilizing the potential of hair cortisol analysis in a large sample of maltreated and nonmaltreated children and adolescents. Method Participants included 537 children and adolescents (3–16 years; 272 females) with maltreatment (n = 245) or without maltreatment histories (n = 292). Maltreated subjects were recruited from child protection services (CPS; n = 95), youth psychiatric services (n = 56), and the community (n = 94). Maltreatment was coded using the Maltreatment Classification System drawing on caregiver interviews and complemented with CPS records. Caregivers and teachers reported on child mental health. HCC were assessed in the first 3 cm hair segment. Results Analyses uniformly supported that maltreatment coincides with a gradual and dose-dependent reduction in HCC from 9 to 10 years onwards relative to nonmaltreated controls. This pattern emerged consistently from both group comparisons between maltreated and nonmaltreated subjects (27.6% HCC reduction in maltreated 9–16-year-olds) and dimensional analyses within maltreated subjects, with lower HCC related to greater maltreatment chronicity and number of subtypes. Moreover, both group comparisons and dimensional analyses within maltreated youth revealed that relative HCC reduction mediates the effect of maltreatment on externalizing symptoms. Conclusions From middle childhood onwards, maltreatment coincides with a relative reduction in cortisol secretion, which, in turn, may predispose to externalizing symptoms. En ligne : http://dx.doi.org/10.1111/jcpp.12700 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317 [article] Reduced hair cortisol after maltreatment mediates externalizing symptoms in middle childhood and adolescence [Texte imprimé et/ou numérique] / Lars O. WHITE, Auteur ; Marcus ISING, Auteur ; Kai VON KLITZING, Auteur ; Susan SIERAU, Auteur ; Andrea MICHEL, Auteur ; Annette M. KLEIN, Auteur ; Anna ANDREAS, Auteur ; Jan KEIL, Auteur ; Leonhard QUINTERO, Auteur ; Bertram MÜLLER-MYHSOK, Auteur ; Manfred UHR, Auteur ; Ruth GAUSCHE, Auteur ; Jody T. MANLY, Auteur ; Michael J. CROWLEY, Auteur ; Clemens KIRSCHBAUM, Auteur ; Tobias STALDER, Auteur . - p.998-1007. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-9 (September 2017) . - p.998-1007 Mots-clés : Hair cortisol  maltreatment  neglect  externalizing symptoms Index. décimale : PER Périodiques Résumé : Background The enduring impact of childhood maltreatment on biological systems and ensuing psychopathology remains incompletely understood. Long-term effects of stress may be reflected in cumulative cortisol secretion over several months, which is now quantifiable via hair cortisol concentrations (HCC). We conducted a first comprehensive investigation utilizing the potential of hair cortisol analysis in a large sample of maltreated and nonmaltreated children and adolescents. Method Participants included 537 children and adolescents (3–16 years; 272 females) with maltreatment (n = 245) or without maltreatment histories (n = 292). Maltreated subjects were recruited from child protection services (CPS; n = 95), youth psychiatric services (n = 56), and the community (n = 94). Maltreatment was coded using the Maltreatment Classification System drawing on caregiver interviews and complemented with CPS records. Caregivers and teachers reported on child mental health. HCC were assessed in the first 3 cm hair segment. Results Analyses uniformly supported that maltreatment coincides with a gradual and dose-dependent reduction in HCC from 9 to 10 years onwards relative to nonmaltreated controls. This pattern emerged consistently from both group comparisons between maltreated and nonmaltreated subjects (27.6% HCC reduction in maltreated 9–16-year-olds) and dimensional analyses within maltreated subjects, with lower HCC related to greater maltreatment chronicity and number of subtypes. Moreover, both group comparisons and dimensional analyses within maltreated youth revealed that relative HCC reduction mediates the effect of maltreatment on externalizing symptoms. Conclusions From middle childhood onwards, maltreatment coincides with a relative reduction in cortisol secretion, which, in turn, may predispose to externalizing symptoms. En ligne : http://dx.doi.org/10.1111/jcpp.12700 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317

Differential associations of parental harshness and parental disengagement with overall cortisol output at 15 years: Implications for adolescent mental health / Jenalee R. DOOM in Development and Psychopathology, 34-1 (February 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-1 (February 2022) . - p.129-146 Titre : Differential associations of parental harshness and parental disengagement with overall cortisol output at 15 years: Implications for adolescent mental health Type de document : Texte imprimé et/ou numérique Auteurs : Jenalee R. DOOM, Auteur ; Melissa K. PECKINS, Auteur ; Tyler C. HEIN, Auteur ; Hailey L. DOTTERER, Auteur ; Colter MITCHELL, Auteur ; Nestor L. LOPEZ-DURAN, Auteur ; Jeanne BROOKS-GUNN, Auteur ; Sara MCLANAHAN, Auteur ; Luke W. HYDE, Auteur ; James L. ABELSON, Auteur ; Christopher S. MONK, Auteur Article en page(s) : p.129-146 Langues : Anglais (eng) Mots-clés : adolescence  depressive symptoms  hair cortisol  parental disengagement  parental harshness Index. décimale : PER Périodiques Résumé : Psychosocial stress in childhood and adolescence is linked to stress system dysregulation, although few studies have examined the relative impacts of parental harshness and parental disengagement. This study prospectively tested whether parental harshness and disengagement show differential associations with overall cortisol output in adolescence. Associations between overall cortisol output and adolescent mental health problems were tested concurrently. Adolescents from the Fragile Families and Child Wellbeing Study (FFCWS) provided hair samples for cortisol assay at 15 years (N = 171). Caregivers reported on parental harshness and disengagement experiences at 1, 3, 5, 9, and 15 years, and adolescents reported at 15 years. Both parent and adolescent reported depressive and anxiety symptoms and antisocial behaviors at 15. Greater parental harshness from 1?15 years, and harshness reported at 15 years in particular, was associated with higher overall cortisol output at 15. Greater parental disengagement from 1?15 years, and disengagement at 1 year specifically, was associated with lower cortisol output. There were no significant associations between cortisol output and depressive symptoms, anxiety symptoms, or antisocial behaviors. These results suggest that the unique variances of parental harshness and disengagement may have opposing associations with cortisol output at 15 years, with unclear implications for adolescent mental health. En ligne : http://dx.doi.org/10.1017/s0954579420000954 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Differential associations of parental harshness and parental disengagement with overall cortisol output at 15 years: Implications for adolescent mental health [Texte imprimé et/ou numérique] / Jenalee R. DOOM, Auteur ; Melissa K. PECKINS, Auteur ; Tyler C. HEIN, Auteur ; Hailey L. DOTTERER, Auteur ; Colter MITCHELL, Auteur ; Nestor L. LOPEZ-DURAN, Auteur ; Jeanne BROOKS-GUNN, Auteur ; Sara MCLANAHAN, Auteur ; Luke W. HYDE, Auteur ; James L. ABELSON, Auteur ; Christopher S. MONK, Auteur . - p.129-146. Langues : Anglais (eng) in Development and Psychopathology > 34-1 (February 2022) . - p.129-146 Mots-clés : adolescence  depressive symptoms  hair cortisol  parental disengagement  parental harshness Index. décimale : PER Périodiques Résumé : Psychosocial stress in childhood and adolescence is linked to stress system dysregulation, although few studies have examined the relative impacts of parental harshness and parental disengagement. This study prospectively tested whether parental harshness and disengagement show differential associations with overall cortisol output in adolescence. Associations between overall cortisol output and adolescent mental health problems were tested concurrently. Adolescents from the Fragile Families and Child Wellbeing Study (FFCWS) provided hair samples for cortisol assay at 15 years (N = 171). Caregivers reported on parental harshness and disengagement experiences at 1, 3, 5, 9, and 15 years, and adolescents reported at 15 years. Both parent and adolescent reported depressive and anxiety symptoms and antisocial behaviors at 15. Greater parental harshness from 1?15 years, and harshness reported at 15 years in particular, was associated with higher overall cortisol output at 15. Greater parental disengagement from 1?15 years, and disengagement at 1 year specifically, was associated with lower cortisol output. There were no significant associations between cortisol output and depressive symptoms, anxiety symptoms, or antisocial behaviors. These results suggest that the unique variances of parental harshness and disengagement may have opposing associations with cortisol output at 15 years, with unclear implications for adolescent mental health. En ligne : http://dx.doi.org/10.1017/s0954579420000954 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Risk and resilience in Syrian refugee children: A multisystem analysis / Elie G. KARAM ; Andrew K. MAY ; Michael PLUESS ; Michael J. RIEDER ; Demelza SMEETH ; Stan VAN UUM in Development and Psychopathology, 35-5 (December 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-5 (December 2023) . - p.2275-2287 Titre : Risk and resilience in Syrian refugee children: A multisystem analysis Type de document : Texte imprimé et/ou numérique Auteurs : Elie G. KARAM, Auteur ; Andrew K. MAY, Auteur ; Michael PLUESS, Auteur ; Michael J. RIEDER, Auteur ; Demelza SMEETH, Auteur ; Stan VAN UUM, Auteur Article en page(s) : p.2275-2287 Mots-clés : hair cortisol  mental health  polygenic scores  refugee children  resilience Index. décimale : PER Périodiques Résumé : Refugee children are often exposed to substantial trauma, placing them at increased risk for mental illness. However, this risk can be mitigated by a capacity for resilience, conferred from multiple ecological systems (e.g., family, community), including at an individual biological level. We examined the ability of hair cortisol concentrations and polygenic scores for mental health to predict risk and resilience in a sample of Syrian refugee children (n = 1359). Children were categorized as either at-risk or resilient depending on clinical thresholds for posttraumatic stress disorder, depression, and externalizing behavior problems. Logistic regression was used to examine main and interacting effects while controlling for covariates. Elevated hair cortisol concentrations were significantly associated with reduced resilience (odds ratio (OR)=0.58, 95%CI [0.40, 0.83]) while controlling for levels of war exposure. Polygenic scores for depression, self-harm, and neuroticism were not found to have any significant main effects. However, a significant interaction emerged between hair cortisol and polygenic scores for depression (OR=0.04, 95%CI [0.003 0.47]), suggesting that children predisposed to depression were more at risk for mental health problems when hair cortisol concentrations were high. Our results suggest that biomarkers (separately and in combination) might support early identification of refugee children at risk for mental health problems. En ligne : https://dx.doi.org/10.1017/S0954579423000433 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519 [article] Risk and resilience in Syrian refugee children: A multisystem analysis [Texte imprimé et/ou numérique] / Elie G. KARAM, Auteur ; Andrew K. MAY, Auteur ; Michael PLUESS, Auteur ; Michael J. RIEDER, Auteur ; Demelza SMEETH, Auteur ; Stan VAN UUM, Auteur . - p.2275-2287. in Development and Psychopathology > 35-5 (December 2023) . - p.2275-2287 Mots-clés : hair cortisol  mental health  polygenic scores  refugee children  resilience Index. décimale : PER Périodiques Résumé : Refugee children are often exposed to substantial trauma, placing them at increased risk for mental illness. However, this risk can be mitigated by a capacity for resilience, conferred from multiple ecological systems (e.g., family, community), including at an individual biological level. We examined the ability of hair cortisol concentrations and polygenic scores for mental health to predict risk and resilience in a sample of Syrian refugee children (n = 1359). Children were categorized as either at-risk or resilient depending on clinical thresholds for posttraumatic stress disorder, depression, and externalizing behavior problems. Logistic regression was used to examine main and interacting effects while controlling for covariates. Elevated hair cortisol concentrations were significantly associated with reduced resilience (odds ratio (OR)=0.58, 95%CI [0.40, 0.83]) while controlling for levels of war exposure. Polygenic scores for depression, self-harm, and neuroticism were not found to have any significant main effects. However, a significant interaction emerged between hair cortisol and polygenic scores for depression (OR=0.04, 95%CI [0.003 0.47]), suggesting that children predisposed to depression were more at risk for mental health problems when hair cortisol concentrations were high. Our results suggest that biomarkers (separately and in combination) might support early identification of refugee children at risk for mental health problems. En ligne : https://dx.doi.org/10.1017/S0954579423000433 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=519