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Cortical Variability in the Sensory-Evoked Response in Autism / Sarah M. HAIGH in Journal of Autism and Developmental Disorders, 45-5 (May 2015)
[article]
Titre : Cortical Variability in the Sensory-Evoked Response in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Sarah M. HAIGH, Auteur ; David J. HEEGER, Auteur ; Ilan DINSTEIN, Auteur ; Nancy MINSHEW, Auteur ; Marlene BEHRMANN, Auteur Article en page(s) : p.1176-1190 Langues : Anglais (eng) Mots-clés : Autism fMRI Sensory-evoked Variability Index. décimale : PER Périodiques Résumé : Previous findings have shown that individuals with autism spectrum disorder (ASD) evince greater intra-individual variability (IIV) in their sensory-evoked fMRI responses compared to typical control participants. We explore the robustness of this finding with a new sample of high-functioning adults with autism. Participants were presented with visual, somatosensory and auditory stimuli in the scanner whilst they completed a one-back task. While ASD and control participants were statistically indistinguishable with respect to behavioral responses, the new ASD group exhibited greater IIV relative to controls. We also show that the IIV was equivalent across hemispheres and remained stable over the duration of the experiment. This suggests that greater cortical IIV may be a replicable characteristic of sensory systems in autism. En ligne : http://dx.doi.org/10.1007/s10803-014-2276-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259
in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1176-1190[article] Cortical Variability in the Sensory-Evoked Response in Autism [Texte imprimé et/ou numérique] / Sarah M. HAIGH, Auteur ; David J. HEEGER, Auteur ; Ilan DINSTEIN, Auteur ; Nancy MINSHEW, Auteur ; Marlene BEHRMANN, Auteur . - p.1176-1190.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1176-1190
Mots-clés : Autism fMRI Sensory-evoked Variability Index. décimale : PER Périodiques Résumé : Previous findings have shown that individuals with autism spectrum disorder (ASD) evince greater intra-individual variability (IIV) in their sensory-evoked fMRI responses compared to typical control participants. We explore the robustness of this finding with a new sample of high-functioning adults with autism. Participants were presented with visual, somatosensory and auditory stimuli in the scanner whilst they completed a one-back task. While ASD and control participants were statistically indistinguishable with respect to behavioral responses, the new ASD group exhibited greater IIV relative to controls. We also show that the IIV was equivalent across hemispheres and remained stable over the duration of the experiment. This suggests that greater cortical IIV may be a replicable characteristic of sensory systems in autism. En ligne : http://dx.doi.org/10.1007/s10803-014-2276-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259