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Brief Report: CANTAB Performance and Brain Structure in Pediatric Patients with Asperger Syndrome / Liane KAUFMANN in Journal of Autism and Developmental Disorders, 43-6 (June 2013)
[article]
Titre : Brief Report: CANTAB Performance and Brain Structure in Pediatric Patients with Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Liane KAUFMANN, Auteur ; Sibylle ZOTTER, Auteur ; Silvia PIXNER, Auteur ; Marc STARKE, Auteur ; Edda HABERLANDT, Auteur ; Maria STEINMAYR-GENSLUCKNER, Auteur ; Karl EGGER, Auteur ; Michael SCHOCKE, Auteur ; Elisabeth M. WEISS, Auteur ; Josef MARKSTEINER, Auteur Article en page(s) : p.1483-1490 Langues : Anglais (eng) Mots-clés : Asperger syndrome Structural brain imaging Neurocognition CANTAB Spatial working memory Executive functions Index. décimale : PER Périodiques Résumé : By merging neuropsychological (CANTAB/Cambridge Neuropsychological Test Automated Battery) and structural brain imaging data (voxel-based-morphometry) the present study sought to identify the neurocognitive correlates of executive functions in individuals with Asperger syndrome (AS) compared to healthy controls. Results disclosed subtle group differences regarding response speed on only one CANTAB subtest that is thought to tap fronto-executive network functions (SWM/spatial working memory). Across all participants, SWM performance was significantly associated with two brain regions (precentral gyrus white matter, precuneus grey matter), thus suggesting a close link between fronto-executive functions (SWM) and circumscribed fronto-parietal brain structures. Finally, symptom severity (ADOS total score) was best predicted by response speed on a set-shifting task (IES) thought to tap fronto-striatal functions (corrected R2 56 %). En ligne : http://dx.doi.org/10.1007/s10803-012-1686-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201
in Journal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1483-1490[article] Brief Report: CANTAB Performance and Brain Structure in Pediatric Patients with Asperger Syndrome [Texte imprimé et/ou numérique] / Liane KAUFMANN, Auteur ; Sibylle ZOTTER, Auteur ; Silvia PIXNER, Auteur ; Marc STARKE, Auteur ; Edda HABERLANDT, Auteur ; Maria STEINMAYR-GENSLUCKNER, Auteur ; Karl EGGER, Auteur ; Michael SCHOCKE, Auteur ; Elisabeth M. WEISS, Auteur ; Josef MARKSTEINER, Auteur . - p.1483-1490.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1483-1490
Mots-clés : Asperger syndrome Structural brain imaging Neurocognition CANTAB Spatial working memory Executive functions Index. décimale : PER Périodiques Résumé : By merging neuropsychological (CANTAB/Cambridge Neuropsychological Test Automated Battery) and structural brain imaging data (voxel-based-morphometry) the present study sought to identify the neurocognitive correlates of executive functions in individuals with Asperger syndrome (AS) compared to healthy controls. Results disclosed subtle group differences regarding response speed on only one CANTAB subtest that is thought to tap fronto-executive network functions (SWM/spatial working memory). Across all participants, SWM performance was significantly associated with two brain regions (precentral gyrus white matter, precuneus grey matter), thus suggesting a close link between fronto-executive functions (SWM) and circumscribed fronto-parietal brain structures. Finally, symptom severity (ADOS total score) was best predicted by response speed on a set-shifting task (IES) thought to tap fronto-striatal functions (corrected R2 56 %). En ligne : http://dx.doi.org/10.1007/s10803-012-1686-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201 Executive and Visuo-motor Function in Adolescents and Adults with Autism Spectrum Disorder / Michael SACHSE in Journal of Autism and Developmental Disorders, 43-5 (May 2013)
[article]
Titre : Executive and Visuo-motor Function in Adolescents and Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Michael SACHSE, Auteur ; Sabine SCHLITT, Auteur ; Daniela HAINZ, Auteur ; Angela CIARAMIDARO, Auteur ; Shella SCHIRMAN, Auteur ; Henrik WALTER, Auteur ; Fritz POUSTKA, Auteur ; Sven BÖLTE, Auteur ; Christine M. FREITAG, Auteur Article en page(s) : p.1222-1235 Langues : Anglais (eng) Mots-clés : Autism Executive functions Reaction time Movement time Information processing CANTAB Index. décimale : PER Périodiques Résumé : This study broadly examines executive (EF) and visuo-motor function in 30 adolescent and adult individuals with high-functioning autism spectrum disorder (ASD) in comparison to 28 controls matched for age, gender, and IQ. ASD individuals showed impaired spatial working memory, whereas planning, cognitive flexibility, and inhibition were spared. Pure movement execution during visuo-motor information processing also was intact. In contrast, execution time of reading, naming, and of visuo-motor information processing tasks including a choice component was increased in the ASD group. Results of this study are in line with previous studies reporting only minimal EF difficulties in older individuals with ASD when assessed by computerized tasks. The finding of impaired visuo-motor information processing should be accounted for in further neuropsychological studies in ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1668-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1222-1235[article] Executive and Visuo-motor Function in Adolescents and Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Michael SACHSE, Auteur ; Sabine SCHLITT, Auteur ; Daniela HAINZ, Auteur ; Angela CIARAMIDARO, Auteur ; Shella SCHIRMAN, Auteur ; Henrik WALTER, Auteur ; Fritz POUSTKA, Auteur ; Sven BÖLTE, Auteur ; Christine M. FREITAG, Auteur . - p.1222-1235.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-5 (May 2013) . - p.1222-1235
Mots-clés : Autism Executive functions Reaction time Movement time Information processing CANTAB Index. décimale : PER Périodiques Résumé : This study broadly examines executive (EF) and visuo-motor function in 30 adolescent and adult individuals with high-functioning autism spectrum disorder (ASD) in comparison to 28 controls matched for age, gender, and IQ. ASD individuals showed impaired spatial working memory, whereas planning, cognitive flexibility, and inhibition were spared. Pure movement execution during visuo-motor information processing also was intact. In contrast, execution time of reading, naming, and of visuo-motor information processing tasks including a choice component was increased in the ASD group. Results of this study are in line with previous studies reporting only minimal EF difficulties in older individuals with ASD when assessed by computerized tasks. The finding of impaired visuo-motor information processing should be accounted for in further neuropsychological studies in ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1668-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=195