1 recherche sur le mot-clé 'Chromosome 22q11.2DS'

Working Memory Impairments in Chromosome 22q11.2 Deletion Syndrome: The Roles of Anxiety and Stress Physiology / Ashley F. P. SANDERS in Journal of Autism and Developmental Disorders, 47-4 (April 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-4 (April 2017) . - p.992-1005 Titre : Working Memory Impairments in Chromosome 22q11.2 Deletion Syndrome: The Roles of Anxiety and Stress Physiology Type de document : Texte imprimé et/ou numérique Auteurs : Ashley F. P. SANDERS, Auteur ; Diana A. HOBBS, Auteur ; David D. STEPHENSON, Auteur ; Robert D. LAIRD, Auteur ; Elliott A. BEATON, Auteur Article en page(s) : p.992-1005 Langues : Anglais (eng) Mots-clés : Anxiety  Chromosome 22q11.2DS  DiGeorge Syndrome  Stress  Velocardiofacial Syndrome  Working memory Index. décimale : PER Périodiques Résumé : Stress and anxiety have a negative impact on working memory systems by competing for executive resources and attention. Broad memory deficits, anxiety, and elevated stress have been reported in individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS). We investigated anxiety and physiological stress reactivity in relation to visuospatial working memory impairments in 20 children with 22q11.2DS and 32 typically developing (TD) children ages 7 to 16. Children with 22q11.2DS demonstrated poorer working memory, reduced post-stress respiratory sinus arrhythmia recovery, and overall increased levels of cortisol in comparison to TD children. Anxiety, but not physiological stress responsivity, mediated the relationship between 22q11.2DS diagnosis and visuospatial working memory impairment. Findings indicate that anxiety exacerbates impaired working memory in children with 22q11.2DS. En ligne : http://dx.doi.org/10.1007/s10803-016-3011-2 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3048 [article] Working Memory Impairments in Chromosome 22q11.2 Deletion Syndrome: The Roles of Anxiety and Stress Physiology [Texte imprimé et/ou numérique] / Ashley F. P. SANDERS, Auteur ; Diana A. HOBBS, Auteur ; David D. STEPHENSON, Auteur ; Robert D. LAIRD, Auteur ; Elliott A. BEATON, Auteur . - p.992-1005. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-4 (April 2017) . - p.992-1005 Mots-clés : Anxiety  Chromosome 22q11.2DS  DiGeorge Syndrome  Stress  Velocardiofacial Syndrome  Working memory Index. décimale : PER Périodiques Résumé : Stress and anxiety have a negative impact on working memory systems by competing for executive resources and attention. Broad memory deficits, anxiety, and elevated stress have been reported in individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS). We investigated anxiety and physiological stress reactivity in relation to visuospatial working memory impairments in 20 children with 22q11.2DS and 32 typically developing (TD) children ages 7 to 16. Children with 22q11.2DS demonstrated poorer working memory, reduced post-stress respiratory sinus arrhythmia recovery, and overall increased levels of cortisol in comparison to TD children. Anxiety, but not physiological stress responsivity, mediated the relationship between 22q11.2DS diagnosis and visuospatial working memory impairment. Findings indicate that anxiety exacerbates impaired working memory in children with 22q11.2DS. En ligne : http://dx.doi.org/10.1007/s10803-016-3011-2 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3048