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Editorial: Accelerated epigenetic ageing as a consequence of early environmental adversity / Barbara FRANKE in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)
[article]
Titre : Editorial: Accelerated epigenetic ageing as a consequence of early environmental adversity Type de document : Texte imprimé et/ou numérique Auteurs : Barbara FRANKE, Auteur Article en page(s) : p.1219-1221 Langues : Anglais (eng) Mots-clés : Adolescent Humans Epigenesis, Genetic Aging/genetics DNA methylation Great Smoky Mountains Study environmental adversity epigenetic ageing Index. décimale : PER Périodiques Résumé : In this editorial, I discuss findings and implications of a hypothesis-generating study by Copeland and colleagues showing that early adverse events related to unpredictability as well as a cumulative score summarising environmental adversity in childhood and adolescence are linked to accelerated epigenetic ageing. The setting of this study is the longitudinal Great Smoky Mountains Study, a richly phenotyped longitudinal cohort with biological information. In my discussion, I focus on potential mechanisms behind the reported findings and opportunities for next steps, for example provided by the richness of data in the cohort used in this study. En ligne : http://dx.doi.org/10.1111/jcpp.13711 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489
in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1219-1221[article] Editorial: Accelerated epigenetic ageing as a consequence of early environmental adversity [Texte imprimé et/ou numérique] / Barbara FRANKE, Auteur . - p.1219-1221.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1219-1221
Mots-clés : Adolescent Humans Epigenesis, Genetic Aging/genetics DNA methylation Great Smoky Mountains Study environmental adversity epigenetic ageing Index. décimale : PER Périodiques Résumé : In this editorial, I discuss findings and implications of a hypothesis-generating study by Copeland and colleagues showing that early adverse events related to unpredictability as well as a cumulative score summarising environmental adversity in childhood and adolescence are linked to accelerated epigenetic ageing. The setting of this study is the longitudinal Great Smoky Mountains Study, a richly phenotyped longitudinal cohort with biological information. In my discussion, I focus on potential mechanisms behind the reported findings and opportunities for next steps, for example provided by the richness of data in the cohort used in this study. En ligne : http://dx.doi.org/10.1111/jcpp.13711 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=489