[article]
Titre : |
Why some children with externalising problems develop internalising symptoms: testing two pathways in a genetically sensitive cohort study |
Type de document : |
Texte imprimé et/ou numérique |
Auteurs : |
Jasmin WERTZ, Auteur ; Helena ZAVOS, Auteur ; Timothy MATTHEWS, Auteur ; Kirsten HARVEY, Auteur ; Alice HUNT, Auteur ; Carmine M. PARIANTE, Auteur ; Louise ARSENEAULT, Auteur |
Article en page(s) : |
p.738-746 |
Langues : |
Anglais (eng) |
Mots-clés : |
Externalising and internalising problems failure model genetic influence development |
Index. décimale : |
PER Périodiques |
Résumé : |
Background Children with externalising problems are at risk of developing internalising problems as they grow older. The pathways underlying this developmental association remain to be elucidated. We tested two processes that could explain why some children with externalising problems develop internalising symptoms in preadolescence: a mediation model whereby the association between early externalising and later new internalising symptoms is explained by negative experiences; and a genetic model, whereby genes influence both problems. Methods We used data from the Environmental Risk (E-Risk) Study, a 1994–1995 birth cohort of 2,232 twins born in England and Wales. We assessed externalising and internalising problems using combined mothers’ and teachers’ ratings at age 5 and 12. We measured bullying victimisation, maternal dissatisfaction and academic difficulties between age 7 and 10 and used linear regression analyses to test the effects of these negative experiences on the association between early externalising and later internalising problems. We employed a Cholesky decomposition to examine the genetic influences on the association. Results Children with externalising problems at age 5 showed increased rates of new internalising problems at age 12 (r = .24, p < .001). Negative experiences accounted for some of the association between early externalising and later internalising problems. Behavioural-genetic analyses indicated that genes influencing early externalising problems also affected later internalising problems. Conclusions Our findings highlight the role of genetic influences in explaining why some children with externalising problems develop internalising symptoms in preadolescence. Negative experiences also contribute to the association, possibly through gene–environment interplay. Mental health professionals should monitor the development of internalising symptoms in young children with externalising problems. |
En ligne : |
http://dx.doi.org/10.1111/jcpp.12333 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 |
in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.738-746
[article] Why some children with externalising problems develop internalising symptoms: testing two pathways in a genetically sensitive cohort study [Texte imprimé et/ou numérique] / Jasmin WERTZ, Auteur ; Helena ZAVOS, Auteur ; Timothy MATTHEWS, Auteur ; Kirsten HARVEY, Auteur ; Alice HUNT, Auteur ; Carmine M. PARIANTE, Auteur ; Louise ARSENEAULT, Auteur . - p.738-746. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 56-7 (July 2015) . - p.738-746
Mots-clés : |
Externalising and internalising problems failure model genetic influence development |
Index. décimale : |
PER Périodiques |
Résumé : |
Background Children with externalising problems are at risk of developing internalising problems as they grow older. The pathways underlying this developmental association remain to be elucidated. We tested two processes that could explain why some children with externalising problems develop internalising symptoms in preadolescence: a mediation model whereby the association between early externalising and later new internalising symptoms is explained by negative experiences; and a genetic model, whereby genes influence both problems. Methods We used data from the Environmental Risk (E-Risk) Study, a 1994–1995 birth cohort of 2,232 twins born in England and Wales. We assessed externalising and internalising problems using combined mothers’ and teachers’ ratings at age 5 and 12. We measured bullying victimisation, maternal dissatisfaction and academic difficulties between age 7 and 10 and used linear regression analyses to test the effects of these negative experiences on the association between early externalising and later internalising problems. We employed a Cholesky decomposition to examine the genetic influences on the association. Results Children with externalising problems at age 5 showed increased rates of new internalising problems at age 12 (r = .24, p < .001). Negative experiences accounted for some of the association between early externalising and later internalising problems. Behavioural-genetic analyses indicated that genes influencing early externalising problems also affected later internalising problems. Conclusions Our findings highlight the role of genetic influences in explaining why some children with externalising problems develop internalising symptoms in preadolescence. Negative experiences also contribute to the association, possibly through gene–environment interplay. Mental health professionals should monitor the development of internalising symptoms in young children with externalising problems. |
En ligne : |
http://dx.doi.org/10.1111/jcpp.12333 |
Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 |
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