Adults with autism spectrum disorder and the criminal justice system: An investigation of prevalence of contact with the criminal justice system, risk factors and sex differences in a specialist assessment service / Charlotte E. BLACKMORE in Autism, 26-8 (November 2022)  

Public ISBD [article]  inAutism > 26-8 (November 2022) . - p.2098-2107 Titre : Adults with autism spectrum disorder and the criminal justice system: An investigation of prevalence of contact with the criminal justice system, risk factors and sex differences in a specialist assessment service Type de document : Texte imprimé et/ou numérique Auteurs : Charlotte E. BLACKMORE, Auteur ; Emma L. WOODHOUSE, Auteur ; Nicola GILLAN, Auteur ; Ellie WILSON, Auteur ; Karen L. ASHWOOD, Auteur ; Vladimira STOENCHEVA, Auteur ; Alexandra NOLAN, Auteur ; Gráinne M. MCALONAN, Auteur ; Dene M. ROBERTSON, Auteur ; Susannah WHITWELL, Auteur ; Quinton DEELEY, Auteur ; Michael C. CRAIG, Auteur ; Janneke ZINKSTOK, Auteur ; Rob WICHERS, Auteur ; Debbie SPAIN, Auteur ; Ged ROBERTS, Auteur ; Declan GM MURPHY, Auteur ; Clodagh M. MURPHY, Auteur ; Eileen DALY, Auteur Article en page(s) : p.2098-2107 Langues : Anglais (eng) Mots-clés : Adult  Humans  Male  Female  Autism Spectrum Disorder/epidemiology  Criminal Law  Prevalence  Sex Characteristics  Risk Factors  autism spectrum disorders  crime  criminal justice system  offending  risk factors  research, authorship and/or publication of this article. Index. décimale : PER Périodiques Résumé : There has been growing interest in offending and contact with the criminal justice system (CJS) by people with autism spectrum disorder (ASD). However, it is not clear whether people with ASD offend more than those without ASD. Studies have started to look at whether there are particular offences people with ASD are more likely to commit and whether there are any factors that can affect whether someone comes into contact with the CJS as a potential suspect. This study looked at the patients who attended an ASD diagnostic service over a 17-year period to see the rate of contact with the CJS of those who were diagnosed with ASD and whether there were any particular factors that might increase the risk of CJS contact. Nearly a quarter of the ASD group had some contact with the CJS as a potential suspect. Factors that seemed to increase whether someone with ASD was more likely to have contact with the CJS were being male, being diagnosed with ADHD, and being diagnosed with psychosis. This study is one of the largest studies to investigate the rate of CJS contact as a potential suspect in a sample of adults with ASD in an attempt to give a clearer picture of what might influence someone with ASD to engage in offending behaviour in order to try to see what mental health services can offer to reduce the likelihood of someone with ASD coming into contact with the CJS, for example, treatment for another condition or support. En ligne : http://dx.doi.org/10.1177/13623613221081343 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 [article] Adults with autism spectrum disorder and the criminal justice system: An investigation of prevalence of contact with the criminal justice system, risk factors and sex differences in a specialist assessment service [Texte imprimé et/ou numérique] / Charlotte E. BLACKMORE, Auteur ; Emma L. WOODHOUSE, Auteur ; Nicola GILLAN, Auteur ; Ellie WILSON, Auteur ; Karen L. ASHWOOD, Auteur ; Vladimira STOENCHEVA, Auteur ; Alexandra NOLAN, Auteur ; Gráinne M. MCALONAN, Auteur ; Dene M. ROBERTSON, Auteur ; Susannah WHITWELL, Auteur ; Quinton DEELEY, Auteur ; Michael C. CRAIG, Auteur ; Janneke ZINKSTOK, Auteur ; Rob WICHERS, Auteur ; Debbie SPAIN, Auteur ; Ged ROBERTS, Auteur ; Declan GM MURPHY, Auteur ; Clodagh M. MURPHY, Auteur ; Eileen DALY, Auteur . - p.2098-2107. Langues : Anglais (eng) in Autism > 26-8 (November 2022) . - p.2098-2107 Mots-clés : Adult  Humans  Male  Female  Autism Spectrum Disorder/epidemiology  Criminal Law  Prevalence  Sex Characteristics  Risk Factors  autism spectrum disorders  crime  criminal justice system  offending  risk factors  research, authorship and/or publication of this article. Index. décimale : PER Périodiques Résumé : There has been growing interest in offending and contact with the criminal justice system (CJS) by people with autism spectrum disorder (ASD). However, it is not clear whether people with ASD offend more than those without ASD. Studies have started to look at whether there are particular offences people with ASD are more likely to commit and whether there are any factors that can affect whether someone comes into contact with the CJS as a potential suspect. This study looked at the patients who attended an ASD diagnostic service over a 17-year period to see the rate of contact with the CJS of those who were diagnosed with ASD and whether there were any particular factors that might increase the risk of CJS contact. Nearly a quarter of the ASD group had some contact with the CJS as a potential suspect. Factors that seemed to increase whether someone with ASD was more likely to have contact with the CJS were being male, being diagnosed with ADHD, and being diagnosed with psychosis. This study is one of the largest studies to investigate the rate of CJS contact as a potential suspect in a sample of adults with ASD in an attempt to give a clearer picture of what might influence someone with ASD to engage in offending behaviour in order to try to see what mental health services can offer to reduce the likelihood of someone with ASD coming into contact with the CJS, for example, treatment for another condition or support. En ligne : http://dx.doi.org/10.1177/13623613221081343 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488

Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic / C. Ellie WILSON in Journal of Autism and Developmental Disorders, 43-11 (November 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2515-2525 Titre : Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic Type de document : Texte imprimé et/ou numérique Auteurs : C. Ellie WILSON, Auteur ; Nicola GILLAN, Auteur ; Deborah SPAIN, Auteur ; Dene ROBERTSON, Auteur ; Gedeon ROBERTS, Auteur ; Clodagh M. MURPHY, Auteur ; Stefanos MALTEZOS, Auteur ; Janneke ZINKSTOK, Auteur ; Katie JOHNSTON, Auteur ; Christina DARDANI, Auteur ; Chris OHLSEN, Auteur ; Quinton DEELEY, Auteur ; Michael C. CRAIG, Auteur ; Maria A. MENDEZ, Auteur ; Francesca HAPPE, Auteur ; Declan G. M. MURPHY, Auteur Article en page(s) : p.2515-2525 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Diagnosis  Prevalence  DSM-5 Index. décimale : PER Périodiques Résumé : An Autism Spectrum Disorder (ASD) diagnosis is often used to access services. We investigated whether ASD diagnostic outcome varied when DSM-5 was used compared to ICD-10R and DSM-IV-TR in a clinical sample of 150 intellectually able adults. Of those diagnosed with an ASD using ICD-10R, 56 % met DSM-5 ASD criteria. A further 19 % met DSM-5 (draft) criteria for Social Communication Disorder. Of those diagnosed with Autistic Disorder/Asperger Syndrome on DSM-IV-TR, 78 % met DSM-5 ASD criteria. Sensitivity of DSM-5 was significantly increased by reducing the number of criteria required for a DSM-5 diagnosis, or by rating ‘uncertain’ criteria as ‘present’, without sacrificing specificity. Reduced rates of ASD diagnosis may mean some ASD individuals will be unable to access clinical services. En ligne : http://dx.doi.org/10.1007/s10803-013-1799-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 [article] Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic [Texte imprimé et/ou numérique] / C. Ellie WILSON, Auteur ; Nicola GILLAN, Auteur ; Deborah SPAIN, Auteur ; Dene ROBERTSON, Auteur ; Gedeon ROBERTS, Auteur ; Clodagh M. MURPHY, Auteur ; Stefanos MALTEZOS, Auteur ; Janneke ZINKSTOK, Auteur ; Katie JOHNSTON, Auteur ; Christina DARDANI, Auteur ; Chris OHLSEN, Auteur ; Quinton DEELEY, Auteur ; Michael C. CRAIG, Auteur ; Maria A. MENDEZ, Auteur ; Francesca HAPPE, Auteur ; Declan G. M. MURPHY, Auteur . - p.2515-2525. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-11 (November 2013) . - p.2515-2525 Mots-clés : Autism Spectrum Disorder  Diagnosis  Prevalence  DSM-5 Index. décimale : PER Périodiques Résumé : An Autism Spectrum Disorder (ASD) diagnosis is often used to access services. We investigated whether ASD diagnostic outcome varied when DSM-5 was used compared to ICD-10R and DSM-IV-TR in a clinical sample of 150 intellectually able adults. Of those diagnosed with an ASD using ICD-10R, 56 % met DSM-5 ASD criteria. A further 19 % met DSM-5 (draft) criteria for Social Communication Disorder. Of those diagnosed with Autistic Disorder/Asperger Syndrome on DSM-IV-TR, 78 % met DSM-5 ASD criteria. Sensitivity of DSM-5 was significantly increased by reducing the number of criteria required for a DSM-5 diagnosis, or by rating ‘uncertain’ criteria as ‘present’, without sacrificing specificity. Reduced rates of ASD diagnosis may mean some ASD individuals will be unable to access clinical services. En ligne : http://dx.doi.org/10.1007/s10803-013-1799-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217

Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample / Fiona S. MCEWEN in Journal of Child Psychology and Psychiatry, 57-2 (February 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.161-170 Titre : Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample Type de document : Texte imprimé et/ou numérique Auteurs : Fiona S. MCEWEN, Auteur ; Catherine S. STEWART, Auteur ; Emma COLVERT, Auteur ; Emma WOODHOUSE, Auteur ; Sarah CURRAN, Auteur ; Nicola GILLAN, Auteur ; Victoria HALLETT, Auteur ; Stephanie LIETZ, Auteur ; Tracy GARNETT, Auteur ; Angelica RONALD, Auteur ; Declan MURPHY, Auteur ; Francesca HAPPE, Auteur ; Patrick BOLTON, Auteur Article en page(s) : p.161-170 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  adolescence  assessment  diagnosis Index. décimale : PER Périodiques Résumé : Background Increasing numbers of people are being referred for the assessment of autism spectrum disorder (ASD). The NICE (UK) and the American Academy of Pediatrics recommend gathering a developmental history using a tool that operationalises ICD/DSM criteria. However, the best-established diagnostic interview instruments are time consuming, costly and rarely used outside national specialist centres. What is needed is a brief, cost-effective measure validated in community settings. We tested the Development and Well-Being Assessment (DAWBA) for diagnosing ASD in a sample of children/adolescents representative of those presenting in community mental health settings. Methods A general population sample of twins (TEDS) was screened and 276 adolescents were selected as at low (CAST score < 12; n = 164) or high risk for ASD (CAST score ? 15 and/or parent reported that ASD suspected/previously diagnosed; n = 112). Parents completed the ASD module of the DAWBA interview by telephone or online. Families were visited at home: the ADI-R and autism diagnostic observation schedule (ADOS) were completed to allow a best-estimate research diagnosis of ASD to be made. Results Development and Well-Being Assessment ASD symptom scores correlated highly with ADI-R algorithm scores (? = .82, p < .001). Good sensitivity (0.88) and specificity (0.85) were achieved using DAWBA computerised algorithms. Clinician review of responses to DAWBA questions minimally changed sensitivity (0.86) and specificity (0.87). Positive (0.82–0.95) and negative (0.90) predictive values were high. Eighty-six per cent of children were correctly classified. Performance was improved by using it in conjunction with the ADOS. Conclusions The DAWBA is a brief structured interview that showed good sensitivity and specificity in this general population sample. It requires little training, is easy to administer (online or by interview) and diagnosis is aided by an algorithm. It holds promise as a tool for assisting with assessment in community settings and may help services implement the recommendations made by NICE and the American Academy of Pediatrics regarding diagnosis of young people on the autism spectrum. En ligne : http://dx.doi.org/10.1111/jcpp.12447 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280 [article] Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample [Texte imprimé et/ou numérique] / Fiona S. MCEWEN, Auteur ; Catherine S. STEWART, Auteur ; Emma COLVERT, Auteur ; Emma WOODHOUSE, Auteur ; Sarah CURRAN, Auteur ; Nicola GILLAN, Auteur ; Victoria HALLETT, Auteur ; Stephanie LIETZ, Auteur ; Tracy GARNETT, Auteur ; Angelica RONALD, Auteur ; Declan MURPHY, Auteur ; Francesca HAPPE, Auteur ; Patrick BOLTON, Auteur . - p.161-170. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.161-170 Mots-clés : Autism spectrum disorder  adolescence  assessment  diagnosis Index. décimale : PER Périodiques Résumé : Background Increasing numbers of people are being referred for the assessment of autism spectrum disorder (ASD). The NICE (UK) and the American Academy of Pediatrics recommend gathering a developmental history using a tool that operationalises ICD/DSM criteria. However, the best-established diagnostic interview instruments are time consuming, costly and rarely used outside national specialist centres. What is needed is a brief, cost-effective measure validated in community settings. We tested the Development and Well-Being Assessment (DAWBA) for diagnosing ASD in a sample of children/adolescents representative of those presenting in community mental health settings. Methods A general population sample of twins (TEDS) was screened and 276 adolescents were selected as at low (CAST score < 12; n = 164) or high risk for ASD (CAST score ? 15 and/or parent reported that ASD suspected/previously diagnosed; n = 112). Parents completed the ASD module of the DAWBA interview by telephone or online. Families were visited at home: the ADI-R and autism diagnostic observation schedule (ADOS) were completed to allow a best-estimate research diagnosis of ASD to be made. Results Development and Well-Being Assessment ASD symptom scores correlated highly with ADI-R algorithm scores (? = .82, p < .001). Good sensitivity (0.88) and specificity (0.85) were achieved using DAWBA computerised algorithms. Clinician review of responses to DAWBA questions minimally changed sensitivity (0.86) and specificity (0.87). Positive (0.82–0.95) and negative (0.90) predictive values were high. Eighty-six per cent of children were correctly classified. Performance was improved by using it in conjunction with the ADOS. Conclusions The DAWBA is a brief structured interview that showed good sensitivity and specificity in this general population sample. It requires little training, is easy to administer (online or by interview) and diagnosis is aided by an algorithm. It holds promise as a tool for assisting with assessment in community settings and may help services implement the recommendations made by NICE and the American Academy of Pediatrics regarding diagnosis of young people on the autism spectrum. En ligne : http://dx.doi.org/10.1111/jcpp.12447 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280

Does sex influence the diagnostic evaluation of autism spectrum disorder in adults? / C. Ellie WILSON in Autism, 20-7 (October 2016)  

Public ISBD [article]  inAutism > 20-7 (October 2016) . - p.808-819 Titre : Does sex influence the diagnostic evaluation of autism spectrum disorder in adults? Type de document : Texte imprimé et/ou numérique Auteurs : C. Ellie WILSON, Auteur ; Clodagh M. MURPHY, Auteur ; Grainne MCALONAN, Auteur ; Dene M ROBERTSON, Auteur ; Debbie SPAIN, Auteur ; Hannah HAYWARD, Auteur ; Emma WOODHOUSE, Auteur ; Quinton DEELEY, Auteur ; Nicola GILLAN, Auteur ; J Chris OHLSEN, Auteur ; Janneke ZINKSTOK, Auteur ; Vladimira STOENCHEVA, Auteur ; Jessica FAULKNER, Auteur ; Hatice YILDIRAN, Auteur ; Vaughan BELL, Auteur ; Neil HAMMOND, Auteur ; Michael C. CRAIG, Auteur ; Declan GM MURPHY, Auteur Article en page(s) : p.808-819 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  diagnosis  females  males  sex differences Index. décimale : PER Périodiques Résumé : It is unknown whether sex influences the diagnostic evaluation of autism spectrum disorder, or whether male and female adults within the spectrum have different symptom profiles. This study reports sex differences in clinical outcomes for 1244 adults (935 males and 309 females) referred for autism spectrum disorder assessment. Significantly, more males (72%) than females (66%) were diagnosed with an autism spectrum disorder of any subtype (x2?=?4.09; p?=?0.04). In high-functioning autism spectrum disorder adults (IQ?>?70; N?=?827), there were no significant sex differences in severity of socio-communicative domain symptoms. Males had significantly more repetitive behaviours/restricted interests than females (p?=?0.001, d?=?0.3). A multivariate analysis of variance indicated a significant interaction between autism spectrum disorder subtype (full-autism spectrum disorder/partial-autism spectrum disorder) and sex: in full-autism spectrum disorder, males had more severe socio-communicative symptoms than females; for partial-autism spectrum disorder, the reverse was true. There were no sex differences in prevalence of co-morbid psychopathologies. Sex influenced diagnostic evaluation in a clinical sample of adults with suspected autism spectrum disorder. The sexes may present with different manifestations of the autism spectrum disorder phenotype and differences vary by diagnostic subtype. Understanding and awareness of adult female repetitive behaviours/restricted interests warrant attention and sex-specific diagnostic assessment tools may need to be considered. En ligne : http://dx.doi.org/10.1177/1362361315611381 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293 [article] Does sex influence the diagnostic evaluation of autism spectrum disorder in adults? [Texte imprimé et/ou numérique] / C. Ellie WILSON, Auteur ; Clodagh M. MURPHY, Auteur ; Grainne MCALONAN, Auteur ; Dene M ROBERTSON, Auteur ; Debbie SPAIN, Auteur ; Hannah HAYWARD, Auteur ; Emma WOODHOUSE, Auteur ; Quinton DEELEY, Auteur ; Nicola GILLAN, Auteur ; J Chris OHLSEN, Auteur ; Janneke ZINKSTOK, Auteur ; Vladimira STOENCHEVA, Auteur ; Jessica FAULKNER, Auteur ; Hatice YILDIRAN, Auteur ; Vaughan BELL, Auteur ; Neil HAMMOND, Auteur ; Michael C. CRAIG, Auteur ; Declan GM MURPHY, Auteur . - p.808-819. Langues : Anglais (eng) in Autism > 20-7 (October 2016) . - p.808-819 Mots-clés : autism spectrum disorder  diagnosis  females  males  sex differences Index. décimale : PER Périodiques Résumé : It is unknown whether sex influences the diagnostic evaluation of autism spectrum disorder, or whether male and female adults within the spectrum have different symptom profiles. This study reports sex differences in clinical outcomes for 1244 adults (935 males and 309 females) referred for autism spectrum disorder assessment. Significantly, more males (72%) than females (66%) were diagnosed with an autism spectrum disorder of any subtype (x2?=?4.09; p?=?0.04). In high-functioning autism spectrum disorder adults (IQ?>?70; N?=?827), there were no significant sex differences in severity of socio-communicative domain symptoms. Males had significantly more repetitive behaviours/restricted interests than females (p?=?0.001, d?=?0.3). A multivariate analysis of variance indicated a significant interaction between autism spectrum disorder subtype (full-autism spectrum disorder/partial-autism spectrum disorder) and sex: in full-autism spectrum disorder, males had more severe socio-communicative symptoms than females; for partial-autism spectrum disorder, the reverse was true. There were no sex differences in prevalence of co-morbid psychopathologies. Sex influenced diagnostic evaluation in a clinical sample of adults with suspected autism spectrum disorder. The sexes may present with different manifestations of the autism spectrum disorder phenotype and differences vary by diagnostic subtype. Understanding and awareness of adult female repetitive behaviours/restricted interests warrant attention and sex-specific diagnostic assessment tools may need to be considered. En ligne : http://dx.doi.org/10.1177/1362361315611381 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=293

Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls / Victoria HALLETT in Journal of Child Psychology and Psychiatry, 54-11 (November 2013)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1176-1185 Titre : Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls Type de document : Texte imprimé et/ou numérique Auteurs : Victoria HALLETT, Auteur ; Angelica RONALD, Auteur ; Emma COLVERT, Auteur ; Catherine S. AMES, Auteur ; Emma WOODHOUSE, Auteur ; Stephanie LIETZ, Auteur ; Tracy GARNETT, Auteur ; Nicola GILLAN, Auteur ; Frühling V. RIJSDIJK, Auteur ; Lawrence SCAHILL, Auteur ; Patrick BOLTON, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.1176-1185 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  anxiety  twin  siblings  comorbidity Index. décimale : PER Périodiques Résumé : Background Although many children with autism spectrum disorders (ASDs) experience difficulties with anxiety, the manifestation of these difficulties remains unresolved. The current study assessed anxiety in a large population-based twin sample, aged 10–15 years. Phenotypic analyses were used to explore anxiety symptoms in children with ASDs, their unaffected co-twins and a control sample. Methods Participants included 146 families from the Twins Early Development Study (TEDS) where one or both children had a suspected ASD. Eighty control families were also included. The Revised Child Anxiety and Depression scale (Chorpita, Yim, Moffitt, Umemoto Francis, 2000) was completed (self- and parent-report), along with diagnostic and cognitive tests. Children were categorized into four groups (a) ASD (b) Broader Autism Phenotype (BAP: mainly co-twins of children with ASDs, with high subclinical autistic traits) (c) unaffected co-twins (with neither ASDs nor BAP) (d) controls. Results Children in the ASD and BAP groups scored significantly higher than controls for all parent-rated (although not child-rated) anxiety subscales. There were no significant differences between the ASD and BAP groups for any of the parent-rated anxiety subscales. Compared with controls, unaffected co-twins showed significantly heightened Social Anxiety, Generalized Anxiety, and Panic symptoms. Significant associations were observed between certain anxiety subscales and both IQ and ASD symptoms. For example, greater parent-rated Social Anxiety was associated with higher IQ and increased social and communicative impairments. Significant interrater correlations were observed for anxiety reports in children with ASDs (r = .27–.54; p .01), their unaffected co-twins (r = .32–.63; p .01) and controls (r = .23–.43; p .01) suggesting that children in this sample with and without ASD symptoms were able to report on their anxiety symptoms with some accuracy. Conclusions These findings support previous reports of heightened anxiety in children with ASDs, at least on parent-reported measures. Unaffected co-twins of children with ASDs also showed increased anxiety, generating questions about the potential etiological overlap between ASDs and anxiety. Progress in this area now depends on more refined anxiety measurement in ASDs and continued investigation of interrater differences. En ligne : http://dx.doi.org/10.1111/jcpp.12068 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217 [article] Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls [Texte imprimé et/ou numérique] / Victoria HALLETT, Auteur ; Angelica RONALD, Auteur ; Emma COLVERT, Auteur ; Catherine S. AMES, Auteur ; Emma WOODHOUSE, Auteur ; Stephanie LIETZ, Auteur ; Tracy GARNETT, Auteur ; Nicola GILLAN, Auteur ; Frühling V. RIJSDIJK, Auteur ; Lawrence SCAHILL, Auteur ; Patrick BOLTON, Auteur ; Francesca HAPPE, Auteur . - p.1176-1185. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 54-11 (November 2013) . - p.1176-1185 Mots-clés : Autism spectrum disorders  anxiety  twin  siblings  comorbidity Index. décimale : PER Périodiques Résumé : Background Although many children with autism spectrum disorders (ASDs) experience difficulties with anxiety, the manifestation of these difficulties remains unresolved. The current study assessed anxiety in a large population-based twin sample, aged 10–15 years. Phenotypic analyses were used to explore anxiety symptoms in children with ASDs, their unaffected co-twins and a control sample. Methods Participants included 146 families from the Twins Early Development Study (TEDS) where one or both children had a suspected ASD. Eighty control families were also included. The Revised Child Anxiety and Depression scale (Chorpita, Yim, Moffitt, Umemoto Francis, 2000) was completed (self- and parent-report), along with diagnostic and cognitive tests. Children were categorized into four groups (a) ASD (b) Broader Autism Phenotype (BAP: mainly co-twins of children with ASDs, with high subclinical autistic traits) (c) unaffected co-twins (with neither ASDs nor BAP) (d) controls. Results Children in the ASD and BAP groups scored significantly higher than controls for all parent-rated (although not child-rated) anxiety subscales. There were no significant differences between the ASD and BAP groups for any of the parent-rated anxiety subscales. Compared with controls, unaffected co-twins showed significantly heightened Social Anxiety, Generalized Anxiety, and Panic symptoms. Significant associations were observed between certain anxiety subscales and both IQ and ASD symptoms. For example, greater parent-rated Social Anxiety was associated with higher IQ and increased social and communicative impairments. Significant interrater correlations were observed for anxiety reports in children with ASDs (r = .27–.54; p .01), their unaffected co-twins (r = .32–.63; p .01) and controls (r = .23–.43; p .01) suggesting that children in this sample with and without ASD symptoms were able to report on their anxiety symptoms with some accuracy. Conclusions These findings support previous reports of heightened anxiety in children with ASDs, at least on parent-reported measures. Unaffected co-twins of children with ASDs also showed increased anxiety, generating questions about the potential etiological overlap between ASDs and anxiety. Progress in this area now depends on more refined anxiety measurement in ASDs and continued investigation of interrater differences. En ligne : http://dx.doi.org/10.1111/jcpp.12068 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=217

Exploring the cognitive features in children with autism spectrum disorder, their co-twins, and typically developing children within a population-based sample / Victoria E. A. BRUNSDON in Journal of Child Psychology and Psychiatry, 56-8 (August 2015)  

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A new test of advanced theory of mind: The “Strange Stories Film Task” captures social processing differences in adults with autism spectrum disorders / Kim MURRAY in Autism Research, 10-6 (June 2017)  

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Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us? / Tim CADMAN in Autism Research, 8-5 (October 2015)  

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The mental health of individuals referred for assessment of autism spectrum disorder in adulthood: A clinic report / Ailsa J RUSSELL in Autism, 20-5 (July 2016)  

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