Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Détail de l'auteur
Auteur Bonnie AUYEUNG |
Documents disponibles écrits par cet auteur (30)
Faire une suggestion Affiner la recherche
Psychometric Properties of the Mandarin Version of the Childhood Autism Spectrum Test (CAST): An Exploratory Study / Xiang SUN in Journal of Autism and Developmental Disorders, 44-7 (July 2014)
[article]
Titre : Psychometric Properties of the Mandarin Version of the Childhood Autism Spectrum Test (CAST): An Exploratory Study Type de document : Texte imprimé et/ou numérique Auteurs : Xiang SUN, Auteur ; Carrie ALLISON, Auteur ; Bonnie AUYEUNG, Auteur ; Fiona E. MATTHEWS, Auteur ; Samuel NORTON, Auteur ; Simon BARON-COHEN, Auteur ; Carol BRAYNE, Auteur Article en page(s) : p.1565-1576 Langues : Anglais (eng) Mots-clés : Autism spectrum conditions Categorical data factor analysis Item response theory CAST China Index. décimale : PER Périodiques Résumé : Limited studies have investigated the latent autistic traits in the mainland Chinese population for autism spectrum conditions (ASC). This study explored the psychometric properties of a Mandarin Chinese version of the CAST in a sample consisting of 737 children in mainstream schools and 50 autistic cases. A combination of categorical data factor analysis and item response theory suggested a good-fit model of a two-factor solution for 28 items on the Mandarin CAST including social and communication, and inflexible/stereotyped language and behaviours (Goodness-of-fit indices: RMSEA = 0.029, CFI = 0.957, TLI = 0.950, SRMR = 0.064). The correlation between the two factors was moderate (GFC = 0.425). This study provided evidence for the CAST as a multidimensional measure for ASC screening in a Chinese population and also showed that the symptom manifestation of ASC in Chinese children shares similarity with western populations. En ligne : http://dx.doi.org/10.1007/s10803-013-2024-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236
in Journal of Autism and Developmental Disorders > 44-7 (July 2014) . - p.1565-1576[article] Psychometric Properties of the Mandarin Version of the Childhood Autism Spectrum Test (CAST): An Exploratory Study [Texte imprimé et/ou numérique] / Xiang SUN, Auteur ; Carrie ALLISON, Auteur ; Bonnie AUYEUNG, Auteur ; Fiona E. MATTHEWS, Auteur ; Samuel NORTON, Auteur ; Simon BARON-COHEN, Auteur ; Carol BRAYNE, Auteur . - p.1565-1576.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-7 (July 2014) . - p.1565-1576
Mots-clés : Autism spectrum conditions Categorical data factor analysis Item response theory CAST China Index. décimale : PER Périodiques Résumé : Limited studies have investigated the latent autistic traits in the mainland Chinese population for autism spectrum conditions (ASC). This study explored the psychometric properties of a Mandarin Chinese version of the CAST in a sample consisting of 737 children in mainstream schools and 50 autistic cases. A combination of categorical data factor analysis and item response theory suggested a good-fit model of a two-factor solution for 28 items on the Mandarin CAST including social and communication, and inflexible/stereotyped language and behaviours (Goodness-of-fit indices: RMSEA = 0.029, CFI = 0.957, TLI = 0.950, SRMR = 0.064). The correlation between the two factors was moderate (GFC = 0.425). This study provided evidence for the CAST as a multidimensional measure for ASC screening in a Chinese population and also showed that the symptom manifestation of ASC in Chinese children shares similarity with western populations. En ligne : http://dx.doi.org/10.1007/s10803-013-2024-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=236 Quantifying and exploring camouflaging in men and women with autism / Meng-Chuan LAI in Autism, 21-6 (August 2017)
[article]
Titre : Quantifying and exploring camouflaging in men and women with autism Type de document : Texte imprimé et/ou numérique Auteurs : Meng-Chuan LAI, Auteur ; Michael V. LOMBARDO, Auteur ; Amber N. V. RUIGROK, Auteur ; Bhismadev CHAKRABARTI, Auteur ; Bonnie AUYEUNG, Auteur ; Peter SZATMARI, Auteur ; Francesca HAPPE, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : p.690-702 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autobiographical descriptions and clinician observations suggest that some individuals with autism, particularly females, ?camouflage? their social communication difficulties, which may require considerable cognitive effort and lead to increased stress, anxiety and depression. Using data from 60 age- and IQ-matched men and women with autism (without intellectual disability), we operationalized camouflaging in adults with autism for the first time as the quantitative discrepancy between the person?s ?external? behavioural presentation in social?interpersonal contexts (measured by the Autism Diagnostic Observation Schedule) and the person?s ?internal? status (dispositional traits measured by the Autism Spectrum Quotient and social cognitive capability measured by the ?Reading the Mind in the Eyes? Test). We found that the operationalized camouflaging measure was not significantly correlated with age or IQ. On average, women with autism had higher camouflaging scores than men with autism (Cohen?s d=0.98), with substantial variability in both groups. Greater camouflaging was associated with more depressive symptoms in men and better signal-detection sensitivity in women with autism. The neuroanatomical association with camouflaging score was largely sex/gender-dependent and significant only in women: from reverse inference, the most correlated cognitive terms were about emotion and memory. The underlying constructs, measurement, mechanisms, consequences and heterogeneity of camouflaging in autism warrant further investigation. En ligne : http://dx.doi.org/10.1177/1362361316671012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=311
in Autism > 21-6 (August 2017) . - p.690-702[article] Quantifying and exploring camouflaging in men and women with autism [Texte imprimé et/ou numérique] / Meng-Chuan LAI, Auteur ; Michael V. LOMBARDO, Auteur ; Amber N. V. RUIGROK, Auteur ; Bhismadev CHAKRABARTI, Auteur ; Bonnie AUYEUNG, Auteur ; Peter SZATMARI, Auteur ; Francesca HAPPE, Auteur ; Simon BARON-COHEN, Auteur . - p.690-702.
Langues : Anglais (eng)
in Autism > 21-6 (August 2017) . - p.690-702
Index. décimale : PER Périodiques Résumé : Autobiographical descriptions and clinician observations suggest that some individuals with autism, particularly females, ?camouflage? their social communication difficulties, which may require considerable cognitive effort and lead to increased stress, anxiety and depression. Using data from 60 age- and IQ-matched men and women with autism (without intellectual disability), we operationalized camouflaging in adults with autism for the first time as the quantitative discrepancy between the person?s ?external? behavioural presentation in social?interpersonal contexts (measured by the Autism Diagnostic Observation Schedule) and the person?s ?internal? status (dispositional traits measured by the Autism Spectrum Quotient and social cognitive capability measured by the ?Reading the Mind in the Eyes? Test). We found that the operationalized camouflaging measure was not significantly correlated with age or IQ. On average, women with autism had higher camouflaging scores than men with autism (Cohen?s d=0.98), with substantial variability in both groups. Greater camouflaging was associated with more depressive symptoms in men and better signal-detection sensitivity in women with autism. The neuroanatomical association with camouflaging score was largely sex/gender-dependent and significant only in women: from reverse inference, the most correlated cognitive terms were about emotion and memory. The underlying constructs, measurement, mechanisms, consequences and heterogeneity of camouflaging in autism warrant further investigation. En ligne : http://dx.doi.org/10.1177/1362361316671012 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=311 A Role for Fetal Testosterone in Human Sex Differences : Implications for Understanding Autism / Bonnie AUYEUNG
Titre : A Role for Fetal Testosterone in Human Sex Differences : Implications for Understanding Autism Type de document : Texte imprimé et/ou numérique Auteurs : Bonnie AUYEUNG, Auteur ; Simon BARON-COHEN, Auteur Année de publication : 2008 Importance : p.185-208 Langues : Anglais (eng) Mots-clés : Testosterone foetale Genre Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=704 A Role for Fetal Testosterone in Human Sex Differences : Implications for Understanding Autism [Texte imprimé et/ou numérique] / Bonnie AUYEUNG, Auteur ; Simon BARON-COHEN, Auteur . - 2008 . - p.185-208.
Langues : Anglais (eng)
Mots-clés : Testosterone foetale Genre Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=704 Exemplaires
Code-barres Cote Support Localisation Section Disponibilité aucun exemplaire Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome / Hannah STEEB in Molecular Autism, (January 2014)
[article]
Titre : Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Hannah STEEB, Auteur ; Jordan RAMSEY, Auteur ; Paul GUEST, Auteur ; Pawel STOCKI, Auteur ; Jason COOPER, Auteur ; Hassan RAHMOUNE, Auteur ; Erin INGUDOMNUKUL, Auteur ; Bonnie AUYEUNG, Auteur ; Liliana RUTA, Auteur ; Simon BARON-COHEN, Auteur ; Sabine BAHN, Auteur Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The higher prevalence of Asperger Syndrome (AS) and other autism spectrum conditions in males has been known for many years. However, recent multiplex immunoassay profiling studies have shown that males and females with AS have distinct proteomic changes in serum. Here, we analysed sera from adults diagnosed with AS (males=14, females=16) and controls (males=13, females=16) not on medication at the time of sample collection, using a combination of multiplex immunoassay and shotgun label-free liquid chromatography mass spectrometry (LC-MSE). The main objective was to identify sex-specific serum protein changes associated with AS. Multiplex immunoassay profiling led to identification of 16 proteins that were significantly altered in AS individuals in a sex-specific manner. Three of these proteins were altered in females (ADIPO, IgA, APOA1), seven were changed in males (BMP6, CTGF, ICAM1, IL-12p70, IL-16, TF, TNF-alpha) and six were changed in both sexes but in opposite directions (CHGA, EPO, IL-3, TENA, PAP, SHBG). Shotgun LC-MSE profiling led to identification of 13 serum proteins which had significant sex-specific changes in the AS group and, of these, 12 were altered in females (APOC2, APOE, ARMC3, CLC4K, FETUB, GLCE, MRRP1, PTPA, RN149, TLE1, TRIPB, ZC3HE) and one protein was altered in males (RGPD4). The free androgen index in females with AS showed an increased ratio of 1.63 compared to controls.CONCLUSION:Taken together, the serum multiplex immunoassay and shotgun LC-MSE profiling results indicate that adult females with AS had alterations in proteins involved mostly in lipid transport and metabolism pathways, while adult males with AS showed changes predominantly in inflammation signalling. These results provide further evidence that the search for biomarkers or novel drug targets in AS may require stratification into male and female subgroups, and could lead to the development of novel targeted treatment approaches. En ligne : http://dx.doi.org/10.1186/2040-2392-5-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=227
in Molecular Autism > (January 2014)[article] Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome [Texte imprimé et/ou numérique] / Hannah STEEB, Auteur ; Jordan RAMSEY, Auteur ; Paul GUEST, Auteur ; Pawel STOCKI, Auteur ; Jason COOPER, Auteur ; Hassan RAHMOUNE, Auteur ; Erin INGUDOMNUKUL, Auteur ; Bonnie AUYEUNG, Auteur ; Liliana RUTA, Auteur ; Simon BARON-COHEN, Auteur ; Sabine BAHN, Auteur.
Langues : Anglais (eng)
in Molecular Autism > (January 2014)
Index. décimale : PER Périodiques Résumé : The higher prevalence of Asperger Syndrome (AS) and other autism spectrum conditions in males has been known for many years. However, recent multiplex immunoassay profiling studies have shown that males and females with AS have distinct proteomic changes in serum. Here, we analysed sera from adults diagnosed with AS (males=14, females=16) and controls (males=13, females=16) not on medication at the time of sample collection, using a combination of multiplex immunoassay and shotgun label-free liquid chromatography mass spectrometry (LC-MSE). The main objective was to identify sex-specific serum protein changes associated with AS. Multiplex immunoassay profiling led to identification of 16 proteins that were significantly altered in AS individuals in a sex-specific manner. Three of these proteins were altered in females (ADIPO, IgA, APOA1), seven were changed in males (BMP6, CTGF, ICAM1, IL-12p70, IL-16, TF, TNF-alpha) and six were changed in both sexes but in opposite directions (CHGA, EPO, IL-3, TENA, PAP, SHBG). Shotgun LC-MSE profiling led to identification of 13 serum proteins which had significant sex-specific changes in the AS group and, of these, 12 were altered in females (APOC2, APOE, ARMC3, CLC4K, FETUB, GLCE, MRRP1, PTPA, RN149, TLE1, TRIPB, ZC3HE) and one protein was altered in males (RGPD4). The free androgen index in females with AS showed an increased ratio of 1.63 compared to controls.CONCLUSION:Taken together, the serum multiplex immunoassay and shotgun LC-MSE profiling results indicate that adult females with AS had alterations in proteins involved mostly in lipid transport and metabolism pathways, while adult males with AS showed changes predominantly in inflammation signalling. These results provide further evidence that the search for biomarkers or novel drug targets in AS may require stratification into male and female subgroups, and could lead to the development of novel targeted treatment approaches. En ligne : http://dx.doi.org/10.1186/2040-2392-5-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=227 Subgrouping siblings of people with autism: Identifying the broader autism phenotype / Emily RUZICH in Autism Research, 9-6 (June 2016)
[article]
Titre : Subgrouping siblings of people with autism: Identifying the broader autism phenotype Type de document : Texte imprimé et/ou numérique Auteurs : Emily RUZICH, Auteur ; Carrie ALLISON, Auteur ; Paula SMITH, Auteur ; Peter WATSON, Auteur ; Bonnie AUYEUNG, Auteur ; Howard RING, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : p.658-665 Langues : Anglais (eng) Mots-clés : autism Autism-Spectrum Quotient autistic traits siblings sex differences broader autism phenotype Index. décimale : PER Périodiques Résumé : We investigate the broader autism phenotype (BAP) in siblings of individuals with autism spectrum conditions (ASC). Autistic traits were measured in typical controls (n?=?2,000), siblings (n?=?496), and volunteers with ASC (n?=?2,322) using the Autism-Spectrum Quotient (AQ), both self-report and parent-report versions. Using cluster analysis of AQ subscale scores, two sibling subgroups were identified for both males and females: a cluster of low-scorers and a cluster of high-scorers. Results show that while siblings as a group have intermediate levels of autistic traits compared to control individuals and participants with ASC, when examined on a cluster level, the low-scoring sibling group is more similar to typical controls while the high-scoring group is more similar to the ASC clinical group. Further investigation into the underlying genetic and epigenetic characteristics of these two subgroups will be informative in understanding autistic traits, both within the general population and in relation to those with a clinical diagnosis. Autism Res 2016, 9: 658–665. © 2015 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research En ligne : http://dx.doi.org/10.1002/aur.1544 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290
in Autism Research > 9-6 (June 2016) . - p.658-665[article] Subgrouping siblings of people with autism: Identifying the broader autism phenotype [Texte imprimé et/ou numérique] / Emily RUZICH, Auteur ; Carrie ALLISON, Auteur ; Paula SMITH, Auteur ; Peter WATSON, Auteur ; Bonnie AUYEUNG, Auteur ; Howard RING, Auteur ; Simon BARON-COHEN, Auteur . - p.658-665.
Langues : Anglais (eng)
in Autism Research > 9-6 (June 2016) . - p.658-665
Mots-clés : autism Autism-Spectrum Quotient autistic traits siblings sex differences broader autism phenotype Index. décimale : PER Périodiques Résumé : We investigate the broader autism phenotype (BAP) in siblings of individuals with autism spectrum conditions (ASC). Autistic traits were measured in typical controls (n?=?2,000), siblings (n?=?496), and volunteers with ASC (n?=?2,322) using the Autism-Spectrum Quotient (AQ), both self-report and parent-report versions. Using cluster analysis of AQ subscale scores, two sibling subgroups were identified for both males and females: a cluster of low-scorers and a cluster of high-scorers. Results show that while siblings as a group have intermediate levels of autistic traits compared to control individuals and participants with ASC, when examined on a cluster level, the low-scoring sibling group is more similar to typical controls while the high-scoring group is more similar to the ASC clinical group. Further investigation into the underlying genetic and epigenetic characteristics of these two subgroups will be informative in understanding autistic traits, both within the general population and in relation to those with a clinical diagnosis. Autism Res 2016, 9: 658–665. © 2015 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research En ligne : http://dx.doi.org/10.1002/aur.1544 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 A symptom level perspective on reactive and proactive aggressive behaviours and ADHD symptoms in childhood / Lydia Gabriela SPEYER in Journal of Child Psychology and Psychiatry, 63-9 (September 2022)
PermalinkThe Autism Spectrum Quotient: Children’s Version (AQ-Child) / Bonnie AUYEUNG in Journal of Autism and Developmental Disorders, 38-7 (August 2008)
PermalinkThe Autism-Spectrum Quotient in siblings of people with Autism / Emily RUZICH in Autism Research, 9-10 (October 2016)
PermalinkThe Autism-Spectrum Quotient in Siblings of People With Autism / Emily RUZICH in Autism Research, 10-2 (February 2017)
PermalinkThe Children’s Empathy Quotient and Systemizing Quotient: Sex Differences in Typical Development and in Autism Spectrum Conditions / Bonnie AUYEUNG in Journal of Autism and Developmental Disorders, 39-11 (November 2009)
PermalinkThe EU-AIMS Longitudinal European Autism Project (LEAP): clinical characterisation / Tony CHARMAN in Molecular Autism, 8 (2017)
PermalinkThe EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders / E. LOTH in Molecular Autism, 8 (2017)
PermalinkThe Extreme Male Brain Theory of Autism: The Role of Fetal Androgens / Simon BARON-COHEN
PermalinkThe Impact of COVID-19 Restrictions on Psychological Distress in Family Caregivers of Children with Neurodevelopmental Disability in the UK / Karri GILLESPIE-SMITH in Journal of Autism and Developmental Disorders, 53-4 (April 2023)
PermalinkThe Mandarin Childhood Autism Spectrum Test (CAST): Sex Differences / Xiang SUN in Journal of Autism and Developmental Disorders, 44-9 (September 2014)
PermalinkUncovering steroidopathy in women with autism: a latent class analysis / Alexa POHL in Molecular Autism, (April 2014)
PermalinkValidation of existing diagnosis of autism in mainland China using standardised diagnostic instruments / Xiang SUN in Autism, 19-8 (November 2015)
PermalinkVariation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children / Teresa TAVASSOLI in Molecular Autism, (July 2012)
PermalinkWhat do parents of children with autism expect from participation in research? A community survey about early autism studies / Sue FLETCHER-WATSON in Autism, 23-1 (January 2019)
PermalinkWhat is available for case identification in autism research in mainland China? / Xiang SUN in Research in Autism Spectrum Disorders, 7-5 (May 2013)
Permalink