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Auteur G. RICHARDS |
Documents disponibles écrits par cet auteur (3)
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[article]
Titre : Autistic traits in adults who have attempted suicide Type de document : Texte imprimé et/ou numérique Auteurs : G. RICHARDS, Auteur ; R. KENNY, Auteur ; S. GRIFFITHS, Auteur ; Carrie ALLISON, Auteur ; D. MOSSE, Auteur ; R. HOLT, Auteur ; R. C. O'CONNOR, Auteur ; Sarah A. CASSIDY, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : 26p. Langues : Anglais (eng) Mots-clés : Asc Asd Asperger syndrome Autism Autism spectrum Autistic traits Depression Mental health Suicidality Suicide Index. décimale : PER Périodiques Résumé : Background: An emerging literature suggests that autistic adults are at increased risk of experiencing suicidal thoughts, making suicidal plans and attempts, and dying by suicide. However, few studies have investigated whether autistic traits are related to suicidal behaviour. The current study examined autistic traits in a sample of adults who reported at least one suicide attempt. Methods: An online questionnaire was advertised between June and September 2017 on suicide prevention websites, research databases, and social media. Participants reported whether they had ever attempted suicide (yes/no), and if so, how many times they had attempted (once/more than once). They also reported diagnosed and suspected mental health or neurodevelopmental conditions, and completed the Autism Spectrum Quotient (AQ). Two hundred forty-five adults accessed the survey; 132 reported having attempted suicide and also completed the AQ. It was hypothesised that AQ total scores and subscale scores would be higher in adults who had attempted suicide more than once compared to adults who had attempted once. These hypotheses were tested using an independent samples t test, Mann-Whitney U tests, and binary logistic regression. Results: Most participants were female (83.3%, male = 12.9%, other = 3.8%), and ages ranged from 18 to 65 (median = 36.00; IQR = 19.00). Total AQ scores, as well as communication and imagination subscale scores were significantly higher in adults who had attempted suicide more than once compared to adults who had attempted suicide once. Even after removing participants with diagnosed or suspected autism (n = 34), 40.6% had an AQ score indicative of clinical concern (>/= 26). Conclusions: The findings suggest that high levels of autistic traits may frequently be present in adults who have attempted suicide, and that AQ scores are higher in those with a history of more than one suicide attempt. It may be possible to better identify suicide risk by screening autistic adults with mental health conditions for suicidal thoughts and behaviours, and by screening people with suicidal thoughts and/or behaviours for autism. En ligne : http://dx.doi.org/10.1186/s13229-019-0274-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402
in Molecular Autism > 10 (2019) . - 26p.[article] Autistic traits in adults who have attempted suicide [Texte imprimé et/ou numérique] / G. RICHARDS, Auteur ; R. KENNY, Auteur ; S. GRIFFITHS, Auteur ; Carrie ALLISON, Auteur ; D. MOSSE, Auteur ; R. HOLT, Auteur ; R. C. O'CONNOR, Auteur ; Sarah A. CASSIDY, Auteur ; Simon BARON-COHEN, Auteur . - 26p.
Langues : Anglais (eng)
in Molecular Autism > 10 (2019) . - 26p.
Mots-clés : Asc Asd Asperger syndrome Autism Autism spectrum Autistic traits Depression Mental health Suicidality Suicide Index. décimale : PER Périodiques Résumé : Background: An emerging literature suggests that autistic adults are at increased risk of experiencing suicidal thoughts, making suicidal plans and attempts, and dying by suicide. However, few studies have investigated whether autistic traits are related to suicidal behaviour. The current study examined autistic traits in a sample of adults who reported at least one suicide attempt. Methods: An online questionnaire was advertised between June and September 2017 on suicide prevention websites, research databases, and social media. Participants reported whether they had ever attempted suicide (yes/no), and if so, how many times they had attempted (once/more than once). They also reported diagnosed and suspected mental health or neurodevelopmental conditions, and completed the Autism Spectrum Quotient (AQ). Two hundred forty-five adults accessed the survey; 132 reported having attempted suicide and also completed the AQ. It was hypothesised that AQ total scores and subscale scores would be higher in adults who had attempted suicide more than once compared to adults who had attempted once. These hypotheses were tested using an independent samples t test, Mann-Whitney U tests, and binary logistic regression. Results: Most participants were female (83.3%, male = 12.9%, other = 3.8%), and ages ranged from 18 to 65 (median = 36.00; IQR = 19.00). Total AQ scores, as well as communication and imagination subscale scores were significantly higher in adults who had attempted suicide more than once compared to adults who had attempted suicide once. Even after removing participants with diagnosed or suspected autism (n = 34), 40.6% had an AQ score indicative of clinical concern (>/= 26). Conclusions: The findings suggest that high levels of autistic traits may frequently be present in adults who have attempted suicide, and that AQ scores are higher in those with a history of more than one suicide attempt. It may be possible to better identify suicide risk by screening autistic adults with mental health conditions for suicidal thoughts and behaviours, and by screening people with suicidal thoughts and/or behaviours for autism. En ligne : http://dx.doi.org/10.1186/s13229-019-0274-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 Maternal steroid levels and the autistic traits of the mother and infant / A. TSOMPANIDIS in Molecular Autism, 12 (2021)
[article]
Titre : Maternal steroid levels and the autistic traits of the mother and infant Type de document : Texte imprimé et/ou numérique Auteurs : A. TSOMPANIDIS, Auteur ; E. AYDIN, Auteur ; E. PADAIGAIT?, Auteur ; G. RICHARDS, Auteur ; Carrie ALLISON, Auteur ; G. HACKETT, Auteur ; T. AUSTIN, Auteur ; R. HOLT, Auteur ; Simon BARON-COHEN, Auteur Article en page(s) : 51 p. Langues : Anglais (eng) Mots-clés : Autism Autistic Traits Estradiol Interaction Pregnancy Prenatal Sex Index. décimale : PER Périodiques Résumé : BACKGROUND: Prenatal sex steroids have been associated with autism in several clinical and epidemiological studies. It is unclear how this relates to the autistic traits of the mother and how early this can be detected during pregnancy and postnatal development. METHODS: Maternal serum was collected from pregnant women (n?=?122) before or during their first ultrasound appointment [mean?=?12.7 (SD?=?0.7) weeks]. Concentrations of the following were measured via immunoassays: testosterone, estradiol, dehydroepiandrosterone sulphate, progesterone; and sex hormone-binding globulin which was used to compute the free fractions of estradiol (FEI) and testosterone (FTI). Standardised human choriogonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A) values were obtained from clinical records corresponding to the same serum samples. Mothers completed the Autism Spectrum Quotient (AQ) and for their infants, the Quantitative Checklist for Autism in Toddlers (Q-CHAT) when the infants were between 18 and 20 months old. RESULTS: FEI was positively associated with maternal autistic traits in univariate (n?=?108, Pearson's r?=?0.22, p?=?0.019) and multiple regression models (semipartial r?=?0.19, p?=?0.048) controlling for maternal age and a diagnosis of PCOS. Maternal estradiol levels significantly interacted with fetal sex in predicting infant Q-CHAT scores, with a positive relationship in males but not females (n?=?100, interaction term: semipartial r?=?0.23, p?=?0.036) after controlling for maternal AQ and other covariates. The opposite was found for standardised hCG values and Q-CHAT scores, with a positive association in females but not in males (n?=?151, interaction term: r?=?-0.25, p?=?0.005). LIMITATIONS: Sample size of this cohort was small, with potential ascertainment bias given elective recruitment. Clinical covariates were controlled in multiple regression models, but additional research is needed to confirm the statistically significant findings in larger cohorts. CONCLUSION: Maternal steroid factors during pregnancy are associated with autistic traits in mothers and their infants. En ligne : http://dx.doi.org/10.1186/s13229-021-00453-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459
in Molecular Autism > 12 (2021) . - 51 p.[article] Maternal steroid levels and the autistic traits of the mother and infant [Texte imprimé et/ou numérique] / A. TSOMPANIDIS, Auteur ; E. AYDIN, Auteur ; E. PADAIGAIT?, Auteur ; G. RICHARDS, Auteur ; Carrie ALLISON, Auteur ; G. HACKETT, Auteur ; T. AUSTIN, Auteur ; R. HOLT, Auteur ; Simon BARON-COHEN, Auteur . - 51 p.
Langues : Anglais (eng)
in Molecular Autism > 12 (2021) . - 51 p.
Mots-clés : Autism Autistic Traits Estradiol Interaction Pregnancy Prenatal Sex Index. décimale : PER Périodiques Résumé : BACKGROUND: Prenatal sex steroids have been associated with autism in several clinical and epidemiological studies. It is unclear how this relates to the autistic traits of the mother and how early this can be detected during pregnancy and postnatal development. METHODS: Maternal serum was collected from pregnant women (n?=?122) before or during their first ultrasound appointment [mean?=?12.7 (SD?=?0.7) weeks]. Concentrations of the following were measured via immunoassays: testosterone, estradiol, dehydroepiandrosterone sulphate, progesterone; and sex hormone-binding globulin which was used to compute the free fractions of estradiol (FEI) and testosterone (FTI). Standardised human choriogonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A) values were obtained from clinical records corresponding to the same serum samples. Mothers completed the Autism Spectrum Quotient (AQ) and for their infants, the Quantitative Checklist for Autism in Toddlers (Q-CHAT) when the infants were between 18 and 20 months old. RESULTS: FEI was positively associated with maternal autistic traits in univariate (n?=?108, Pearson's r?=?0.22, p?=?0.019) and multiple regression models (semipartial r?=?0.19, p?=?0.048) controlling for maternal age and a diagnosis of PCOS. Maternal estradiol levels significantly interacted with fetal sex in predicting infant Q-CHAT scores, with a positive relationship in males but not females (n?=?100, interaction term: semipartial r?=?0.23, p?=?0.036) after controlling for maternal AQ and other covariates. The opposite was found for standardised hCG values and Q-CHAT scores, with a positive association in females but not in males (n?=?151, interaction term: r?=?-0.25, p?=?0.005). LIMITATIONS: Sample size of this cohort was small, with potential ascertainment bias given elective recruitment. Clinical covariates were controlled in multiple regression models, but additional research is needed to confirm the statistically significant findings in larger cohorts. CONCLUSION: Maternal steroid factors during pregnancy are associated with autistic traits in mothers and their infants. En ligne : http://dx.doi.org/10.1186/s13229-021-00453-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=459 The Association Between Autistic Traits and Disordered Eating is Moderated by Sex/Gender and Independent of Anxiety and Depression / A. BARNETT in Journal of Autism and Developmental Disorders, 51-6 (June 2021)
[article]
Titre : The Association Between Autistic Traits and Disordered Eating is Moderated by Sex/Gender and Independent of Anxiety and Depression Type de document : Texte imprimé et/ou numérique Auteurs : A. BARNETT, Auteur ; K. EDWARDS, Auteur ; R. HARPER, Auteur ; E. EVANS, Auteur ; D. ALEXANDER, Auteur ; M. CHOUDHARY, Auteur ; G. RICHARDS, Auteur Article en page(s) : p.1866-1879 Langues : Anglais (eng) Mots-clés : Adolescent Adult Aged Anxiety/psychology Autistic Disorder/psychology Cross-Sectional Studies Depression/psychology Feeding and Eating Disorders/psychology Female Gender Identity Humans Male Middle Aged Sex Factors Surveys and Questionnaires Young Adult Anorexia nervosa Anxiety Autism Autistic traits Bulimia nervosa Depression Disordered eating Eating disorders Gender differences Sex differences Index. décimale : PER Périodiques Résumé : Previous studies have reported positive correlations between autistic traits and disordered eating, though it is unclear whether the association is moderated by sex/gender or whether it is independent of anxiety or depression. We present the findings of an online survey of 691 participants who completed the Autism Spectrum Quotient (AQ), Hospital Anxiety and Depression Scale (HADS), and Eating Attitudes Test-26 (EAT-26). Following a pre-registered analysis plan, we observed positive correlations between AQ and EAT-26 in males and females, with the association being significantly stronger in females. AQ also remained a significant predictor of EAT-26 when anxiety and depression were controlled for statistically. These findings may be relevant when considering therapeutic interventions in disordered eating populations that exhibit autistic traits. En ligne : http://dx.doi.org/10.1007/s10803-020-04669-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452
in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.1866-1879[article] The Association Between Autistic Traits and Disordered Eating is Moderated by Sex/Gender and Independent of Anxiety and Depression [Texte imprimé et/ou numérique] / A. BARNETT, Auteur ; K. EDWARDS, Auteur ; R. HARPER, Auteur ; E. EVANS, Auteur ; D. ALEXANDER, Auteur ; M. CHOUDHARY, Auteur ; G. RICHARDS, Auteur . - p.1866-1879.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.1866-1879
Mots-clés : Adolescent Adult Aged Anxiety/psychology Autistic Disorder/psychology Cross-Sectional Studies Depression/psychology Feeding and Eating Disorders/psychology Female Gender Identity Humans Male Middle Aged Sex Factors Surveys and Questionnaires Young Adult Anorexia nervosa Anxiety Autism Autistic traits Bulimia nervosa Depression Disordered eating Eating disorders Gender differences Sex differences Index. décimale : PER Périodiques Résumé : Previous studies have reported positive correlations between autistic traits and disordered eating, though it is unclear whether the association is moderated by sex/gender or whether it is independent of anxiety or depression. We present the findings of an online survey of 691 participants who completed the Autism Spectrum Quotient (AQ), Hospital Anxiety and Depression Scale (HADS), and Eating Attitudes Test-26 (EAT-26). Following a pre-registered analysis plan, we observed positive correlations between AQ and EAT-26 in males and females, with the association being significantly stronger in females. AQ also remained a significant predictor of EAT-26 when anxiety and depression were controlled for statistically. These findings may be relevant when considering therapeutic interventions in disordered eating populations that exhibit autistic traits. En ligne : http://dx.doi.org/10.1007/s10803-020-04669-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452