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Détail de l'auteur
Auteur Audrey THURM |
Documents disponibles écrits par cet auteur (24)
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Predictors of Language Acquisition in Preschool Children with Autism Spectrum Disorders / Audrey THURM in Journal of Autism and Developmental Disorders, 37-9 (October 2007)
[article]
Titre : Predictors of Language Acquisition in Preschool Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Audrey THURM, Auteur ; Catherine LORD, Auteur ; Li-Ching LEE, Auteur ; Craig J. NEWSCHAFFER, Auteur Année de publication : 2007 Article en page(s) : p.1721-1734 Langues : Anglais (eng) Mots-clés : Autism Language Preschool Predictors Outcome Index. décimale : PER Périodiques Résumé : In 118 children followed from age 2 to 5 (59 with autism, 24 with PDD-NOS and 35 with non-spectrum developmental disabilities), age 2 and age 3 scores of non-verbal ability, receptive communication, expressive communication and socialization were compared as predictors of receptive and expressive language at age 5. Non-verbal cognitive ability at age 2 was generally the strongest predictor of age 5 language, while at age 3 communication scores were a stronger predictor of age 5 language for children with autism. Early joint attention as well as vocal and motor imitation skills were more impaired in children who did not develop language by age 5 (but had relatively strong non-verbal cognitive skills) than in children who did develop language by 5. En ligne : http://dx.doi.org/10.1007/s10803-006-0300-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=175
in Journal of Autism and Developmental Disorders > 37-9 (October 2007) . - p.1721-1734[article] Predictors of Language Acquisition in Preschool Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Audrey THURM, Auteur ; Catherine LORD, Auteur ; Li-Ching LEE, Auteur ; Craig J. NEWSCHAFFER, Auteur . - 2007 . - p.1721-1734.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 37-9 (October 2007) . - p.1721-1734
Mots-clés : Autism Language Preschool Predictors Outcome Index. décimale : PER Périodiques Résumé : In 118 children followed from age 2 to 5 (59 with autism, 24 with PDD-NOS and 35 with non-spectrum developmental disabilities), age 2 and age 3 scores of non-verbal ability, receptive communication, expressive communication and socialization were compared as predictors of receptive and expressive language at age 5. Non-verbal cognitive ability at age 2 was generally the strongest predictor of age 5 language, while at age 3 communication scores were a stronger predictor of age 5 language for children with autism. Early joint attention as well as vocal and motor imitation skills were more impaired in children who did not develop language by age 5 (but had relatively strong non-verbal cognitive skills) than in children who did develop language by 5. En ligne : http://dx.doi.org/10.1007/s10803-006-0300-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=175 Psychometric Study of the Social Responsiveness Scale in Phelan-McDermid Syndrome / Kellie GERGOUDIS in Autism Research, 13-8 (August 2020)
[article]
Titre : Psychometric Study of the Social Responsiveness Scale in Phelan-McDermid Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Kellie GERGOUDIS, Auteur ; Alan WEINBERG, Auteur ; Jonathan TEMPLIN, Auteur ; Cristan FARMER, Auteur ; Alison DURKIN, Auteur ; Jordana WEISSMAN, Auteur ; Paige SIPER, Auteur ; Jennifer FOSS-FEIG, Auteur ; Maria DEL PILAR TRELLES, Auteur ; Jonathan A. BERNSTEIN, Auteur ; Joseph D. BUXBAUM, Auteur ; Elizabeth BERRY-KRAVIS, Auteur ; Craig M. POWELL, Auteur ; Mustafa SAHIN, Auteur ; Latha SOORYA, Auteur ; Audrey THURM, Auteur ; Alexander KOLEVZON, Auteur Article en page(s) : p.1383-1396 Langues : Anglais (eng) Mots-clés : Item Response Theory Phelan-McDermid syndrome autism spectrum disorder behavioral measures intellectual disability Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale-2 (SRS-2) is a quantitative measure used to characterize symptoms of autism spectrum disorder (ASD). However, research suggests that SRS-2 scores are significantly influenced by language ability and intellectual disability (ID). Efforts to refine the SRS-2 by Sturm, Kuhfeld, Kasari, and Mccracken [Journal of Child Psychology and Psychiatry, 58(9), 1053-1061] yielded a shortened form, yet its psychometric properties in populations with severe ID remain unknown. This study aims to examine the psychometric properties of the SRS-2 in Phelan-McDermid syndrome (PMS), a genetic condition associated with ASD and ID, thereby guiding score interpretation in this population and future development of targeted scales. Analyses, including Item Response Theory (IRT), were conducted on a sample of individuals with PMS (n =?91) recruited at six sites nationally. Psychometric properties evaluated include measures of reliability (internal consistency, test-retest reliability) and validity (structural, construct, content). While both SRS-2 forms are reliable, the shortened SRS-2 shows superior validity to the full SRS-2 for measuring ASD symptoms in PMS. On IRT analysis, the shortened SRS-2 shows excellent discrimination and precisely evaluates respondents across a wide range of ASD symptomatology but interpretation is limited by uncertain content validity and small sample size. The shortened SRS-2 shows some promise for use in PMS, but future refinements and additions are needed to develop items that are tailored to identify ASD in children with severe ID and specifically PMS. LAY SUMMARY: This study determined that a shortened form of the Social Responsiveness Scale, Second Edition (SRS-2) shows both promise and limitations for the characterization of autism symptomatology in individuals with Phelan-McDermid syndrome (PMS), a population characterized by intellectual disability (ID). Caution should be used when interpreting SRS-2 scores in individuals with ID and future research should modify existing items and develop new items to improve the SRS-2's ability to accurately characterize autism symptomatology in PMS. Autism Res 2020, 13: 1383-1396. © 2020 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.2299 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430
in Autism Research > 13-8 (August 2020) . - p.1383-1396[article] Psychometric Study of the Social Responsiveness Scale in Phelan-McDermid Syndrome [Texte imprimé et/ou numérique] / Kellie GERGOUDIS, Auteur ; Alan WEINBERG, Auteur ; Jonathan TEMPLIN, Auteur ; Cristan FARMER, Auteur ; Alison DURKIN, Auteur ; Jordana WEISSMAN, Auteur ; Paige SIPER, Auteur ; Jennifer FOSS-FEIG, Auteur ; Maria DEL PILAR TRELLES, Auteur ; Jonathan A. BERNSTEIN, Auteur ; Joseph D. BUXBAUM, Auteur ; Elizabeth BERRY-KRAVIS, Auteur ; Craig M. POWELL, Auteur ; Mustafa SAHIN, Auteur ; Latha SOORYA, Auteur ; Audrey THURM, Auteur ; Alexander KOLEVZON, Auteur . - p.1383-1396.
Langues : Anglais (eng)
in Autism Research > 13-8 (August 2020) . - p.1383-1396
Mots-clés : Item Response Theory Phelan-McDermid syndrome autism spectrum disorder behavioral measures intellectual disability Index. décimale : PER Périodiques Résumé : The Social Responsiveness Scale-2 (SRS-2) is a quantitative measure used to characterize symptoms of autism spectrum disorder (ASD). However, research suggests that SRS-2 scores are significantly influenced by language ability and intellectual disability (ID). Efforts to refine the SRS-2 by Sturm, Kuhfeld, Kasari, and Mccracken [Journal of Child Psychology and Psychiatry, 58(9), 1053-1061] yielded a shortened form, yet its psychometric properties in populations with severe ID remain unknown. This study aims to examine the psychometric properties of the SRS-2 in Phelan-McDermid syndrome (PMS), a genetic condition associated with ASD and ID, thereby guiding score interpretation in this population and future development of targeted scales. Analyses, including Item Response Theory (IRT), were conducted on a sample of individuals with PMS (n =?91) recruited at six sites nationally. Psychometric properties evaluated include measures of reliability (internal consistency, test-retest reliability) and validity (structural, construct, content). While both SRS-2 forms are reliable, the shortened SRS-2 shows superior validity to the full SRS-2 for measuring ASD symptoms in PMS. On IRT analysis, the shortened SRS-2 shows excellent discrimination and precisely evaluates respondents across a wide range of ASD symptomatology but interpretation is limited by uncertain content validity and small sample size. The shortened SRS-2 shows some promise for use in PMS, but future refinements and additions are needed to develop items that are tailored to identify ASD in children with severe ID and specifically PMS. LAY SUMMARY: This study determined that a shortened form of the Social Responsiveness Scale, Second Edition (SRS-2) shows both promise and limitations for the characterization of autism symptomatology in individuals with Phelan-McDermid syndrome (PMS), a population characterized by intellectual disability (ID). Caution should be used when interpreting SRS-2 scores in individuals with ID and future research should modify existing items and develop new items to improve the SRS-2's ability to accurately characterize autism symptomatology in PMS. Autism Res 2020, 13: 1383-1396. © 2020 International Society for Autism Research, Wiley Periodicals, Inc. En ligne : http://dx.doi.org/10.1002/aur.2299 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=430 Repetitive Behavior and Restricted Interests in Young Children with Autism: Comparisons with Controls and Stability Over 2 Years / Lisa JOSEPH in Autism Research, 6-6 (December 2013)
[article]
Titre : Repetitive Behavior and Restricted Interests in Young Children with Autism: Comparisons with Controls and Stability Over 2 Years Type de document : Texte imprimé et/ou numérique Auteurs : Lisa JOSEPH, Auteur ; Audrey THURM, Auteur ; Cristan A. FARMER, Auteur ; Stacy SHUMWAY, Auteur Année de publication : 2013 Article en page(s) : p.584-595 Langues : Anglais (eng) Mots-clés : autism spectrum disorders repetitive behaviors young children trajectory Index. décimale : PER Périodiques Résumé : Restricted, repetitive and stereotyped patterns of behavior, interests and activities [RRBs] are among the core symptoms of autism spectrum disorders (ASD). Previous studies have indicated that RRBs differentiate ASD from other developmental disorders and from typical development. This study examined the presentation of RRBs as reported on the Repetitive Behavior Scale-Revised, a caregiver report, in children with ASD [separated into autism and Pervasive Developmental Disorder-Not Otherwise Specified groups] compared with children with nonspectrum developmental delays or typical development. We examined the role of age, cognitive functioning, sex and social communication impairment as they relate to RRBs. The stability of RRBs in children with autism was also examined over the course of 2 years. Results of the study confirmed that the amount and type of RRBs differs by diagnosis. Age, cognitive functioning, sex and social-communication impairment were not significant correlates. Among children with autism, RRBs remained stable over time. En ligne : http://dx.doi.org/10.1002/aur.1316 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221
in Autism Research > 6-6 (December 2013) . - p.584-595[article] Repetitive Behavior and Restricted Interests in Young Children with Autism: Comparisons with Controls and Stability Over 2 Years [Texte imprimé et/ou numérique] / Lisa JOSEPH, Auteur ; Audrey THURM, Auteur ; Cristan A. FARMER, Auteur ; Stacy SHUMWAY, Auteur . - 2013 . - p.584-595.
Langues : Anglais (eng)
in Autism Research > 6-6 (December 2013) . - p.584-595
Mots-clés : autism spectrum disorders repetitive behaviors young children trajectory Index. décimale : PER Périodiques Résumé : Restricted, repetitive and stereotyped patterns of behavior, interests and activities [RRBs] are among the core symptoms of autism spectrum disorders (ASD). Previous studies have indicated that RRBs differentiate ASD from other developmental disorders and from typical development. This study examined the presentation of RRBs as reported on the Repetitive Behavior Scale-Revised, a caregiver report, in children with ASD [separated into autism and Pervasive Developmental Disorder-Not Otherwise Specified groups] compared with children with nonspectrum developmental delays or typical development. We examined the role of age, cognitive functioning, sex and social communication impairment as they relate to RRBs. The stability of RRBs in children with autism was also examined over the course of 2 years. Results of the study confirmed that the amount and type of RRBs differs by diagnosis. Age, cognitive functioning, sex and social-communication impairment were not significant correlates. Among children with autism, RRBs remained stable over time. En ligne : http://dx.doi.org/10.1002/aur.1316 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 Sex differences in scores on standardized measures of autism symptoms: a multisite integrative data analysis / Aaron J. KAAT in Journal of Child Psychology and Psychiatry, 62-1 (January 2021)
[article]
Titre : Sex differences in scores on standardized measures of autism symptoms: a multisite integrative data analysis Type de document : Texte imprimé et/ou numérique Auteurs : Aaron J. KAAT, Auteur ; Amy M. SHUI, Auteur ; Sheila S. GHODS, Auteur ; Cristan A. FARMER, Auteur ; Amy N. ESLER, Auteur ; Audrey THURM, Auteur ; Stelios GEORGIADES, Auteur ; Stephen M. KANNE, Auteur ; Catherine LORD, Auteur ; Young Shin KIM, Auteur ; Somer L. BISHOP, Auteur Article en page(s) : p.97-106 Langues : Anglais (eng) Mots-clés : Sex differences autism spectrum disorder restricted and repetitive behavior social impairment Index. décimale : PER Périodiques Résumé : BACKGROUND: Concerns have been raised that scores on standard measures of autism spectrum disorder (ASD) symptoms may differ as a function of sex. However, these findings are hindered by small female samples studied thus far. The current study evaluated if, after accounting for age, IQ, and language level, sex affects ASD severity estimates from diagnostic measures among children with ASD. METHODS: Data were obtained from eight sources comprising 27 sites. Linear mixed-effects models, including a random effect for site, were fit for 10 outcomes (Autism Diagnostic Observation Schedule [ADOS] domain-level calibrated severity scores, Autism Diagnostic Interview-Revised [ADI-R] raw scores by age-based algorithm, and raw scores from the two indices on the Social Responsiveness Scale [SRS]). Sex was added to the models after controlling for age, NVIQ, and an indicator for language level. RESULTS: Sex significantly improved model fit for half of the outcomes, but least square mean differences were generally negligible (effect sizes [ES] < 0.20), increasing to small to moderate in adolescence (ES < 0.40). Boys received more severe RRB scores than girls on both the ADOS and ADI-R (age 4 + algorithm), and girls received more severe scores than boys on both SRS indices, which emerged in adolescence. CONCLUSIONS: This study combined several available databases to create the largest sample of girls with ASD diagnoses. We found minimal differences due to sex beyond other known influences on ASD severity indicators. This may suggest that, among children who ultimately receive a clinical ASD diagnosis, severity estimates do not systematically differ to such an extent that sex-specific scoring procedures would be necessary. However, given the limitations inherent in clinically ascertained samples, future research must address questions about systematic sex differences among children or adults who do not receive clinical diagnoses of ASD. Moreover, while the current study helps resolve questions about widely used diagnostic instruments, we could not address sex differences in phenotypic aspects outside of these scores. En ligne : http://dx.doi.org/10.1111/jcpp.13242 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435
in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.97-106[article] Sex differences in scores on standardized measures of autism symptoms: a multisite integrative data analysis [Texte imprimé et/ou numérique] / Aaron J. KAAT, Auteur ; Amy M. SHUI, Auteur ; Sheila S. GHODS, Auteur ; Cristan A. FARMER, Auteur ; Amy N. ESLER, Auteur ; Audrey THURM, Auteur ; Stelios GEORGIADES, Auteur ; Stephen M. KANNE, Auteur ; Catherine LORD, Auteur ; Young Shin KIM, Auteur ; Somer L. BISHOP, Auteur . - p.97-106.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 62-1 (January 2021) . - p.97-106
Mots-clés : Sex differences autism spectrum disorder restricted and repetitive behavior social impairment Index. décimale : PER Périodiques Résumé : BACKGROUND: Concerns have been raised that scores on standard measures of autism spectrum disorder (ASD) symptoms may differ as a function of sex. However, these findings are hindered by small female samples studied thus far. The current study evaluated if, after accounting for age, IQ, and language level, sex affects ASD severity estimates from diagnostic measures among children with ASD. METHODS: Data were obtained from eight sources comprising 27 sites. Linear mixed-effects models, including a random effect for site, were fit for 10 outcomes (Autism Diagnostic Observation Schedule [ADOS] domain-level calibrated severity scores, Autism Diagnostic Interview-Revised [ADI-R] raw scores by age-based algorithm, and raw scores from the two indices on the Social Responsiveness Scale [SRS]). Sex was added to the models after controlling for age, NVIQ, and an indicator for language level. RESULTS: Sex significantly improved model fit for half of the outcomes, but least square mean differences were generally negligible (effect sizes [ES] < 0.20), increasing to small to moderate in adolescence (ES < 0.40). Boys received more severe RRB scores than girls on both the ADOS and ADI-R (age 4 + algorithm), and girls received more severe scores than boys on both SRS indices, which emerged in adolescence. CONCLUSIONS: This study combined several available databases to create the largest sample of girls with ASD diagnoses. We found minimal differences due to sex beyond other known influences on ASD severity indicators. This may suggest that, among children who ultimately receive a clinical ASD diagnosis, severity estimates do not systematically differ to such an extent that sex-specific scoring procedures would be necessary. However, given the limitations inherent in clinically ascertained samples, future research must address questions about systematic sex differences among children or adults who do not receive clinical diagnoses of ASD. Moreover, while the current study helps resolve questions about widely used diagnostic instruments, we could not address sex differences in phenotypic aspects outside of these scores. En ligne : http://dx.doi.org/10.1111/jcpp.13242 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=435 Studying the Emergence of Autism Spectrum Disorders in High-risk Infants: Methodological and Practical Issues / Lonnie ZWAIGENBAUM in Journal of Autism and Developmental Disorders, 37-3 (March 2007)
[article]
Titre : Studying the Emergence of Autism Spectrum Disorders in High-risk Infants: Methodological and Practical Issues Type de document : Texte imprimé et/ou numérique Auteurs : Lonnie ZWAIGENBAUM, Auteur ; Marian SIGMAN, Auteur ; Wendy L. STONE, Auteur ; Alice KAU, Auteur ; Audrey THURM, Auteur ; Jana M. IVERSON, Auteur ; Catherine LORD, Auteur ; Grace T. BARANEK, Auteur ; Susan E. BRYSON, Auteur ; Rebecca LANDA, Auteur ; Ami KLIN, Auteur ; Sally J ROGERS, Auteur Année de publication : 2007 Article en page(s) : p.466-480 Langues : Anglais (eng) Mots-clés : Early-identification Screening Longitudinal-studies Prospective-studies Infant Child-development Siblings Index. décimale : PER Périodiques Résumé : Detecting early signs of autism is essential for timely diagnosis and initiation of effective interventions. Several research groups have initiated prospective studies of high-risk populations including infant siblings, to systematically collect data on early signs within a longitudinal design. Despite the potential advantages of prospective studies of young children at high-risk for autism, there are also significant methodological, ethical and practical challenges. This paper outlines several of these challenges, including those related to sampling (e.g., defining appropriate comparison groups), measurement and clinical implications (e.g., addressing the needs of infants suspected of having early signs). We suggest possible design and implementation strategies to address these various challenges, based on current research efforts in the field and previous studies involving high-risk populations. En ligne : http://dx.doi.org/10.1007/s10803-006-0179-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=651
in Journal of Autism and Developmental Disorders > 37-3 (March 2007) . - p.466-480[article] Studying the Emergence of Autism Spectrum Disorders in High-risk Infants: Methodological and Practical Issues [Texte imprimé et/ou numérique] / Lonnie ZWAIGENBAUM, Auteur ; Marian SIGMAN, Auteur ; Wendy L. STONE, Auteur ; Alice KAU, Auteur ; Audrey THURM, Auteur ; Jana M. IVERSON, Auteur ; Catherine LORD, Auteur ; Grace T. BARANEK, Auteur ; Susan E. BRYSON, Auteur ; Rebecca LANDA, Auteur ; Ami KLIN, Auteur ; Sally J ROGERS, Auteur . - 2007 . - p.466-480.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 37-3 (March 2007) . - p.466-480
Mots-clés : Early-identification Screening Longitudinal-studies Prospective-studies Infant Child-development Siblings Index. décimale : PER Périodiques Résumé : Detecting early signs of autism is essential for timely diagnosis and initiation of effective interventions. Several research groups have initiated prospective studies of high-risk populations including infant siblings, to systematically collect data on early signs within a longitudinal design. Despite the potential advantages of prospective studies of young children at high-risk for autism, there are also significant methodological, ethical and practical challenges. This paper outlines several of these challenges, including those related to sampling (e.g., defining appropriate comparison groups), measurement and clinical implications (e.g., addressing the needs of infants suspected of having early signs). We suggest possible design and implementation strategies to address these various challenges, based on current research efforts in the field and previous studies involving high-risk populations. En ligne : http://dx.doi.org/10.1007/s10803-006-0179-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=651 The ADOS Calibrated Severity Score: Relationship to Phenotypic Variables and Stability over Time / Stacy SHUMWAY in Autism Research, 5-4 (August 2012)
PermalinkThe Early Screening for Autism and Communication Disorders: Field-testing an autism-specific screening tool for children 12 to 36 months of age / Amy M. WETHERBY in Autism, 26-7 (October 2022)
PermalinkThe gesture–language association over time in toddlers with and without language delays / Stacy S. MANWARING in Autism & Developmental Language Impairments, 4 (January-December 2019)
PermalinkThe gesture–language association over time in toddlers with and without language delays / Stacy S. MANWARING in Autism & Developmental Language Impairments, 4 (January-December 2019)
PermalinkWord imageability is associated with expressive vocabulary in children with autism spectrum disorder / Kimberly R. LIN in Autism & Developmental Language Impairments, 7 (January-December 2022)
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