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Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder / Kate JOHNSON in Journal of Autism and Developmental Disorders, 41-7 (July 2011)
[article]
Titre : Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Kate JOHNSON, Auteur ; Anya K. MADDEN, Auteur ; Jessica BRAMHAM, Auteur ; Ailsa RUSSELL, Auteur Année de publication : 2011 Article en page(s) : p.903-912 Langues : Anglais (eng) Mots-clés : Response inhibition Autism ADHD Adults Executive function Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are hypothesised to involve core deficits in executive function. Previous studies have found evidence of a double dissociation between the disorders on specific executive functions (planning and response inhibition). To date most research has been conducted with children. No studies have directly compared the stable cognitive profile of adults. It was hypothesised that adults with ASD would show generally intact response inhibition whereas those with ADHD would show more global impairment. Participants were 24 adults aged 18–55 with high functioning ASD, 24 with ADHD, and 14 age and IQ matched controls. Participants completed three standardised measures of response inhibition. Participants with ASD had generally intact response inhibition but slow response latencies, possibly due to deficits in response initiation. Adults with ADHD did not show the more global impairments hypothesised. There were some significant differences between the clinical groups across measures of inhibition. In terms of performance style, adults with ASD were slow and accurate whilst those with ADHD showed an impulsive style. En ligne : http://dx.doi.org/10.1007/s10803-010-1113-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130
in Journal of Autism and Developmental Disorders > 41-7 (July 2011) . - p.903-912[article] Response Inhibition in Adults with Autism Spectrum Disorder Compared to Attention Deficit/Hyperactivity Disorder [Texte imprimé et/ou numérique] / Kate JOHNSON, Auteur ; Anya K. MADDEN, Auteur ; Jessica BRAMHAM, Auteur ; Ailsa RUSSELL, Auteur . - 2011 . - p.903-912.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-7 (July 2011) . - p.903-912
Mots-clés : Response inhibition Autism ADHD Adults Executive function Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) are hypothesised to involve core deficits in executive function. Previous studies have found evidence of a double dissociation between the disorders on specific executive functions (planning and response inhibition). To date most research has been conducted with children. No studies have directly compared the stable cognitive profile of adults. It was hypothesised that adults with ASD would show generally intact response inhibition whereas those with ADHD would show more global impairment. Participants were 24 adults aged 18–55 with high functioning ASD, 24 with ADHD, and 14 age and IQ matched controls. Participants completed three standardised measures of response inhibition. Participants with ASD had generally intact response inhibition but slow response latencies, possibly due to deficits in response initiation. Adults with ADHD did not show the more global impairments hypothesised. There were some significant differences between the clinical groups across measures of inhibition. In terms of performance style, adults with ASD were slow and accurate whilst those with ADHD showed an impulsive style. En ligne : http://dx.doi.org/10.1007/s10803-010-1113-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=130 Response of neural reward regions to food cues in autism spectrum disorders / Carissa J. CASCIO in Journal of Neurodevelopmental Disorders, 4-1 (December 2012)
[article]
Titre : Response of neural reward regions to food cues in autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Carissa J. CASCIO, Auteur ; J. H. FOSS-FEIG, Auteur ; J. L. HEACOCK, Auteur ; C. R. NEWSOM, Auteur ; R. L. COWAN, Auteur ; M. M. BENNINGFIELD, Auteur ; B. P. ROGERS, Auteur ; A. CAO, Auteur Article en page(s) : p.9 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : BACKGROUND: One hypothesis for the social deficits that characterize autism spectrum disorders (ASD) is diminished neural reward response to social interaction and attachment. Prior research using established monetary reward paradigms as a test of non-social reward to compare with social reward may involve confounds in the ability of individuals with ASD to utilize symbolic representation of money and the abstraction required to interpret monetary gains. Thus, a useful addition to our understanding of neural reward circuitry in ASD includes a characterization of the neural response to primary rewards. METHOD: We asked 17 children with ASD and 18 children without ASD to abstain from eating for at least four hours before an MRI scan in which they viewed images of high-calorie foods. We assessed the neural reward network for increases in the blood oxygenation level dependent (BOLD) signal in response to the food images RESULTS: We found very similar patterns of increased BOLD signal to these images in the two groups; both groups showed increased BOLD signal in the bilateral amygdala, as well as in the nucleus accumbens, orbitofrontal cortex, and insula. Direct group comparisons revealed that the ASD group showed a stronger response to food cues in bilateral insula along the anterior-posterior gradient and in the anterior cingulate cortex than the control group, whereas there were no neural reward regions that showed higher activation for controls than for ASD. CONCLUSION: These results suggest that neural response to primary rewards is not diminished but in fact shows an aberrant enhancement in children with ASD. En ligne : http://dx.doi.org/10.1186/1866-1955-4-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=344
in Journal of Neurodevelopmental Disorders > 4-1 (December 2012) . - p.9[article] Response of neural reward regions to food cues in autism spectrum disorders [Texte imprimé et/ou numérique] / Carissa J. CASCIO, Auteur ; J. H. FOSS-FEIG, Auteur ; J. L. HEACOCK, Auteur ; C. R. NEWSOM, Auteur ; R. L. COWAN, Auteur ; M. M. BENNINGFIELD, Auteur ; B. P. ROGERS, Auteur ; A. CAO, Auteur . - p.9.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 4-1 (December 2012) . - p.9
Index. décimale : PER Périodiques Résumé : BACKGROUND: One hypothesis for the social deficits that characterize autism spectrum disorders (ASD) is diminished neural reward response to social interaction and attachment. Prior research using established monetary reward paradigms as a test of non-social reward to compare with social reward may involve confounds in the ability of individuals with ASD to utilize symbolic representation of money and the abstraction required to interpret monetary gains. Thus, a useful addition to our understanding of neural reward circuitry in ASD includes a characterization of the neural response to primary rewards. METHOD: We asked 17 children with ASD and 18 children without ASD to abstain from eating for at least four hours before an MRI scan in which they viewed images of high-calorie foods. We assessed the neural reward network for increases in the blood oxygenation level dependent (BOLD) signal in response to the food images RESULTS: We found very similar patterns of increased BOLD signal to these images in the two groups; both groups showed increased BOLD signal in the bilateral amygdala, as well as in the nucleus accumbens, orbitofrontal cortex, and insula. Direct group comparisons revealed that the ASD group showed a stronger response to food cues in bilateral insula along the anterior-posterior gradient and in the anterior cingulate cortex than the control group, whereas there were no neural reward regions that showed higher activation for controls than for ASD. CONCLUSION: These results suggest that neural response to primary rewards is not diminished but in fact shows an aberrant enhancement in children with ASD. En ligne : http://dx.doi.org/10.1186/1866-1955-4-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=344 Response of the fetal rat brain to trauma during the 17th to 21st days of gestation / Carys M. BANNISTER in Developmental Medicine & Child Neurology, 28-5 (October 1986)
[article]
Titre : Response of the fetal rat brain to trauma during the 17th to 21st days of gestation Type de document : Texte imprimé et/ou numérique Auteurs : Carys M. BANNISTER, Auteur ; Sonia A. CHAPMAN, Auteur Année de publication : 1986 Article en page(s) : p.600-609 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Ultrasonography has made it possible to diagnose abnormalities of the human central nervous system early in pregnancy. However, more needs to be known about the response of the fetal brain before the mother and fetus are subjected to the risks of complex neurosurgical procedures. This study investigated the effects of trauma on fetal rat brains during a period equivalent to the early part of the second trimester of human pregnancy. Trauma inflicted on the fetal rat brains caused haemorrhage and necrosis of the cerebral hemisphere, which was not followed by significant regeneration of neural tissue. This preliminary study suggests that it cannot be assumed that the fetal brain will regenerate itself after injury, and that this should be considered when making plans for operative procedures on the central nervous system in utero. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=618
in Developmental Medicine & Child Neurology > 28-5 (October 1986) . - p.600-609[article] Response of the fetal rat brain to trauma during the 17th to 21st days of gestation [Texte imprimé et/ou numérique] / Carys M. BANNISTER, Auteur ; Sonia A. CHAPMAN, Auteur . - 1986 . - p.600-609.
Langues : Anglais (eng)
in Developmental Medicine & Child Neurology > 28-5 (October 1986) . - p.600-609
Index. décimale : PER Périodiques Résumé : Ultrasonography has made it possible to diagnose abnormalities of the human central nervous system early in pregnancy. However, more needs to be known about the response of the fetal brain before the mother and fetus are subjected to the risks of complex neurosurgical procedures. This study investigated the effects of trauma on fetal rat brains during a period equivalent to the early part of the second trimester of human pregnancy. Trauma inflicted on the fetal rat brains caused haemorrhage and necrosis of the cerebral hemisphere, which was not followed by significant regeneration of neural tissue. This preliminary study suggests that it cannot be assumed that the fetal brain will regenerate itself after injury, and that this should be considered when making plans for operative procedures on the central nervous system in utero. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=618 Response time variability under slow and fast-incentive conditions in children with ASD, ADHD and ASD+ADHD / Charlotte TYE in Journal of Child Psychology and Psychiatry, 57-12 (December 2016)
[article]
Titre : Response time variability under slow and fast-incentive conditions in children with ASD, ADHD and ASD+ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Charlotte TYE, Auteur ; Katherine A. JOHNSON, Auteur ; Simon P. KELLY, Auteur ; Philip ASHERSON, Auteur ; Jonna KUNTSI, Auteur ; Karen L. ASHWOOD, Auteur ; Bahare AZADI, Auteur ; Patrick BOLTON, Auteur ; Gráinne MCLOUGHLIN, Auteur Article en page(s) : p.1414-1423 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder attention deficit hyperactivity disorder cognition comorbidity reaction time variability Index. décimale : PER Périodiques Résumé : Background Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) show significant behavioural and genetic overlap. Both ADHD and ASD are characterised by poor performance on a range of cognitive tasks. In particular, increased response time variability (RTV) is a promising indicator of risk for both ADHD and ASD. However, it is not clear whether different indices of RTV and changes to RTV according to task conditions are able to discriminate between the two disorders. Methods Children with ASD (n = 19), ADHD (n = 18), ASD + ADHD (n = 29) and typically developing controls (TDC; n = 26) performed a four-choice RT task with slow-baseline and fast-incentive conditions. Performance was characterised by mean RT (MRT), standard deviation of RT (SD-RT), coefficient of variation (CV) and ex-Gaussian distribution measures of Mu, Sigma and Tau. Results In the slow-baseline condition, categorical diagnoses and trait measures converged to indicate that children with ADHD-only and ASD + ADHD demonstrated increased MRT, SD-RT, CV and Tau compared to TDC and ASD-only. Importantly, greater improvement in MRT, SD-RT and Tau was demonstrated in ADHD and ASD + ADHD from slow-baseline to fast-incentive conditions compared to TDC and ASD-only. Conclusions Slower and more variable RTs are markers of ADHD compared to ASD and typically developing controls during slow and less rewarding conditions. Energetic factors and rewards improve task performance to a greater extent in children with ADHD compared to children with ASD. These findings suggest that RTV can be distinguished in ASD, ADHD and ASD + ADHD based on the indices of variability used and the conditions in which they are elicited. Further work identifying neural processes underlying increased RTV is warranted, in order to elucidate disorder-specific and disorder-convergent aetiological pathways. En ligne : http://dx.doi.org/10.1111/jcpp.12608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297
in Journal of Child Psychology and Psychiatry > 57-12 (December 2016) . - p.1414-1423[article] Response time variability under slow and fast-incentive conditions in children with ASD, ADHD and ASD+ADHD [Texte imprimé et/ou numérique] / Charlotte TYE, Auteur ; Katherine A. JOHNSON, Auteur ; Simon P. KELLY, Auteur ; Philip ASHERSON, Auteur ; Jonna KUNTSI, Auteur ; Karen L. ASHWOOD, Auteur ; Bahare AZADI, Auteur ; Patrick BOLTON, Auteur ; Gráinne MCLOUGHLIN, Auteur . - p.1414-1423.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-12 (December 2016) . - p.1414-1423
Mots-clés : Autism spectrum disorder attention deficit hyperactivity disorder cognition comorbidity reaction time variability Index. décimale : PER Périodiques Résumé : Background Attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) show significant behavioural and genetic overlap. Both ADHD and ASD are characterised by poor performance on a range of cognitive tasks. In particular, increased response time variability (RTV) is a promising indicator of risk for both ADHD and ASD. However, it is not clear whether different indices of RTV and changes to RTV according to task conditions are able to discriminate between the two disorders. Methods Children with ASD (n = 19), ADHD (n = 18), ASD + ADHD (n = 29) and typically developing controls (TDC; n = 26) performed a four-choice RT task with slow-baseline and fast-incentive conditions. Performance was characterised by mean RT (MRT), standard deviation of RT (SD-RT), coefficient of variation (CV) and ex-Gaussian distribution measures of Mu, Sigma and Tau. Results In the slow-baseline condition, categorical diagnoses and trait measures converged to indicate that children with ADHD-only and ASD + ADHD demonstrated increased MRT, SD-RT, CV and Tau compared to TDC and ASD-only. Importantly, greater improvement in MRT, SD-RT and Tau was demonstrated in ADHD and ASD + ADHD from slow-baseline to fast-incentive conditions compared to TDC and ASD-only. Conclusions Slower and more variable RTs are markers of ADHD compared to ASD and typically developing controls during slow and less rewarding conditions. Energetic factors and rewards improve task performance to a greater extent in children with ADHD compared to children with ASD. These findings suggest that RTV can be distinguished in ASD, ADHD and ASD + ADHD based on the indices of variability used and the conditions in which they are elicited. Further work identifying neural processes underlying increased RTV is warranted, in order to elucidate disorder-specific and disorder-convergent aetiological pathways. En ligne : http://dx.doi.org/10.1111/jcpp.12608 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 Response Times of Children and Adolescents with Asperger Syndrome on an ‘Advanced’ Test of Theory of Mind / Nils KALAND in Journal of Autism and Developmental Disorders, 37-2 (February 2007)
[article]
Titre : Response Times of Children and Adolescents with Asperger Syndrome on an ‘Advanced’ Test of Theory of Mind Type de document : Texte imprimé et/ou numérique Auteurs : Nils KALAND, Auteur ; Erik Lykke MORTENSEN, Auteur ; Lars SMITH, Auteur Année de publication : 2007 Article en page(s) : p.197-209 Langues : Anglais (eng) Mots-clés : Asperger-syndrome Response-time Theory-of-mind An-‘advanced’-test-of-theory-of-mind Mental-state-vs.-physical-state-inference Index. décimale : PER Périodiques Résumé : In the present study the response times of 10- to 20-year-old participants with Asperger syndrome (AS) (N = 21) of normal intelligence and a control group of typically developing individuals (N = 20) were recorded on a new ‘advanced’ test of theory of mind. This test taps the ability to make mental-state inferences versus physical-state inferences in a story context. The participants with AS were significantly slower than the controls on both tasks. In addition, the differences in response times between mental- and physical-state inference were significantly larger in the AS group than in the control group, suggesting that the clinical group experienced more problems than the controls in making inferences about mental states than about physical states. En ligne : http://dx.doi.org/10.1007/s10803-006-0152-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=625
in Journal of Autism and Developmental Disorders > 37-2 (February 2007) . - p.197-209[article] Response Times of Children and Adolescents with Asperger Syndrome on an ‘Advanced’ Test of Theory of Mind [Texte imprimé et/ou numérique] / Nils KALAND, Auteur ; Erik Lykke MORTENSEN, Auteur ; Lars SMITH, Auteur . - 2007 . - p.197-209.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 37-2 (February 2007) . - p.197-209
Mots-clés : Asperger-syndrome Response-time Theory-of-mind An-‘advanced’-test-of-theory-of-mind Mental-state-vs.-physical-state-inference Index. décimale : PER Périodiques Résumé : In the present study the response times of 10- to 20-year-old participants with Asperger syndrome (AS) (N = 21) of normal intelligence and a control group of typically developing individuals (N = 20) were recorded on a new ‘advanced’ test of theory of mind. This test taps the ability to make mental-state inferences versus physical-state inferences in a story context. The participants with AS were significantly slower than the controls on both tasks. In addition, the differences in response times between mental- and physical-state inference were significantly larger in the AS group than in the control group, suggesting that the clinical group experienced more problems than the controls in making inferences about mental states than about physical states. En ligne : http://dx.doi.org/10.1007/s10803-006-0152-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=625 A response to and caution of "Language is a critical mediator of autistic experiences within the criminal justice system" / Lindsay SHEA in Autism Research, 17-3 (March 2024)
PermalinkResponse to "Application of the Council for Exceptional Children's Standards for Evidence-Based Practices in Special Education" by Schoen et al. [2019] / B. S. STEVENSON in Autism Research, 12-8 (August 2019)
PermalinkResponse to Book Review: Dietary Interventions in Autism Spectrum Disorders: Why They Work When They do, Why They Don’t When They Don’t / Kenneth J. AITKEN in Journal of Autism and Developmental Disorders, 39-11 (November 2009)
PermalinkResponse to “Brief Report: The Effects of Tomatis Sound Therapy on Language in Children with Autism”, July 3, 2007, Journal of Autism and Developmental Disorders / Jan GERRITSEN in Journal of Autism and Developmental Disorders, 38-3 (March 2008)
PermalinkResponse to changing contingencies in infants at high and low risk for autism spectrum disorder / Jessie B. NORTHRUP in Autism Research, 10-7 (July 2017)
PermalinkResponse to commentaries on ‘Low endogenous neural noise in autism’ / Greg DAVIS in Autism, 19-3 (April 2015)
PermalinkResponse to Davis and Plaisted-Grant: Low or high endogenous neural noise in autism spectrum disorder? / David SIMMONS in Autism, 19-3 (April 2015)
PermalinkResponse to Davis and Plaisted-Grant: Psychophysical data do not support the low-noise account of autism / Catherine MANNING in Autism, 19-3 (April 2015)
PermalinkResponse to distress in infants at risk for autism: a prospective longitudinal study / Ted HUTMAN in Journal of Child Psychology and Psychiatry, 51-9 (September 2010)
PermalinkResponse to Distress Varies by Social Impairment and Familiarity in Infants at Risk for Autism / Alexandra C. DOWD in Journal of Autism and Developmental Disorders, 48-11 (November 2018)
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