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Social attention as a cross-cultural transdiagnostic neurodevelopmental risk marker / T. W. FRAZIER in Autism Research, 14-9 (September 2021)
[article]
Titre : Social attention as a cross-cultural transdiagnostic neurodevelopmental risk marker Type de document : Texte imprimé et/ou numérique Auteurs : T. W. FRAZIER, Auteur ; M. ULJAREVIC, Auteur ; I. GHAZAL, Auteur ; E. W. KLINGEMIER, Auteur ; J. LANGFUS, Auteur ; Eric A. YOUNGSTROM, Auteur ; Mohammed ALDOSARI, Auteur ; H. AL-SHAMMARI, Auteur ; S. EL-HAG, Auteur ; M. TOLEFAT, Auteur ; M. ALI, Auteur ; F. A. AL-SHABAN, Auteur Article en page(s) : p.1873-1885 Langues : Anglais (eng) Mots-clés : Adolescent Attention Autism Spectrum Disorder Child Child, Preschool Cross-Cultural Comparison Female Goals Humans Infant Male Mass Screening autism cross-cultural developmental disability risk marker social attention validation Index. décimale : PER Périodiques Résumé : The primary objectives of this study were to evaluate the structure and age-related stability of social attention in English and Arabic-speaking youth and to compare social attention between children with autism spectrum disorder (ASD), other developmental disabilities (DD), and typically-developing controls. Eye-tracking data were collected from US (N = 270) and Qatari (N = 242) youth ages 1-17, including children evaluated for possible ASD. Participants viewed 44 stimuli from seven social paradigms. Fixation was computed for areas of interest within each stimulus. Latent variable models examined the structure of social attention. Generalized estimating equation models examined the effect of age, sex, culture, and diagnostic group on social attention. The best-fitting model included a general social attention factor and six specific factors. Cultural differences in social attention were minimal and social attention was stable across age (r = 0.03), but females showed significantly greater social attention than males (d = 0.28). Social attention was weaker in DD (d = -0.17) and lowest in ASD (d = -0.38) relative to controls. Differences were of sufficient magnitude across areas-of-interest to reliably differentiate DD from controls (AUC = 0.80) and ASD-only from all other cases (AUC = 0.76). A social attention dimension that represents an early-life preference for socially salient information was identified. This preference was cross-culturally consistent and stable across development but stronger in females and weaker in DD, especially ASD. Given rapid and easy-to-collect remote eye tracking administration, social attention measurement may be useful for developmental monitoring. Acquisition of population norms, analogous to height/weight/head circumference, might enhance early screening and tracking of neurodevelopment. LAY SUMMARY: This research found that social attention is a single dimension of behavior that represents a strong preference for social stimuli, is consistent across cultures, stable across age, and stronger in females. Children with developmental disabilities had lower levels of social attention than neurotypical children and children with autism spectrum disorder had the lowest levels of social attention. En ligne : http://dx.doi.org/10.1002/aur.2532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449
in Autism Research > 14-9 (September 2021) . - p.1873-1885[article] Social attention as a cross-cultural transdiagnostic neurodevelopmental risk marker [Texte imprimé et/ou numérique] / T. W. FRAZIER, Auteur ; M. ULJAREVIC, Auteur ; I. GHAZAL, Auteur ; E. W. KLINGEMIER, Auteur ; J. LANGFUS, Auteur ; Eric A. YOUNGSTROM, Auteur ; Mohammed ALDOSARI, Auteur ; H. AL-SHAMMARI, Auteur ; S. EL-HAG, Auteur ; M. TOLEFAT, Auteur ; M. ALI, Auteur ; F. A. AL-SHABAN, Auteur . - p.1873-1885.
Langues : Anglais (eng)
in Autism Research > 14-9 (September 2021) . - p.1873-1885
Mots-clés : Adolescent Attention Autism Spectrum Disorder Child Child, Preschool Cross-Cultural Comparison Female Goals Humans Infant Male Mass Screening autism cross-cultural developmental disability risk marker social attention validation Index. décimale : PER Périodiques Résumé : The primary objectives of this study were to evaluate the structure and age-related stability of social attention in English and Arabic-speaking youth and to compare social attention between children with autism spectrum disorder (ASD), other developmental disabilities (DD), and typically-developing controls. Eye-tracking data were collected from US (N = 270) and Qatari (N = 242) youth ages 1-17, including children evaluated for possible ASD. Participants viewed 44 stimuli from seven social paradigms. Fixation was computed for areas of interest within each stimulus. Latent variable models examined the structure of social attention. Generalized estimating equation models examined the effect of age, sex, culture, and diagnostic group on social attention. The best-fitting model included a general social attention factor and six specific factors. Cultural differences in social attention were minimal and social attention was stable across age (r = 0.03), but females showed significantly greater social attention than males (d = 0.28). Social attention was weaker in DD (d = -0.17) and lowest in ASD (d = -0.38) relative to controls. Differences were of sufficient magnitude across areas-of-interest to reliably differentiate DD from controls (AUC = 0.80) and ASD-only from all other cases (AUC = 0.76). A social attention dimension that represents an early-life preference for socially salient information was identified. This preference was cross-culturally consistent and stable across development but stronger in females and weaker in DD, especially ASD. Given rapid and easy-to-collect remote eye tracking administration, social attention measurement may be useful for developmental monitoring. Acquisition of population norms, analogous to height/weight/head circumference, might enhance early screening and tracking of neurodevelopment. LAY SUMMARY: This research found that social attention is a single dimension of behavior that represents a strong preference for social stimuli, is consistent across cultures, stable across age, and stronger in females. Children with developmental disabilities had lower levels of social attention than neurotypical children and children with autism spectrum disorder had the lowest levels of social attention. En ligne : http://dx.doi.org/10.1002/aur.2532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 Persistence of self-injurious behaviour in autism spectrum disorder over 3 years: a prospective cohort study of risk markers / C. RICHARDS in Journal of Neurodevelopmental Disorders, 8-1 (December 2016)
[article]
Titre : Persistence of self-injurious behaviour in autism spectrum disorder over 3 years: a prospective cohort study of risk markers Type de document : Texte imprimé et/ou numérique Auteurs : C. RICHARDS, Auteur ; J. MOSS, Auteur ; L. NELSON, Auteur ; C. OLIVER, Auteur Article en page(s) : p.21 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Hyperactivity Impulsivity Pain Prevalence Risk marker Self-injury Index. décimale : PER Périodiques Résumé : BACKGROUND: There are few studies documenting the persistence of self-injury in individuals with autism spectrum disorder (ASD) and consequently limited data on behavioural and demographic characteristics associated with persistence. In this longitudinal study, we investigated self-injury in a cohort of individuals with ASD over 3 years to identify behavioural and demographic characteristics associated with persistence. METHODS: Carers of 67 individuals with ASD (Median age of individuals with ASD in years = 13.5, Interquartile Range = 10.00-17.00), completed questionnaires relating to the presence and topography of self-injury at T1 and three years later at T2. Analyses were conducted to evaluate the persistence of self-injury and to evaluate the behavioural and demographic characteristics associated with persistence of self-injury. RESULTS: At T2 self-injurious behaviour had persisted in 77.8 % of individuals. Behavioural correlates of being non-verbal, having lower ability and higher levels of overactivity, impulsivity and repetitive behaviour, were associated with self-injury at both time points. Risk markers of impulsivity (p = 0.021) and deficits in social interaction (p = 0.026) at T1 were associated with the persistence of self-injury over 3 years. CONCLUSIONS: Impulsivity and deficits in social interaction are associated with persistent self-injury in ASD and thus may act as behavioural risk markers. The identification of these risk markers evidences a role for behaviour dysregulation in the development and maintenance of self-injury. The findings have clinical implications for proactive intervention; these behavioural characteristics may be utilised to identify 'at risk' individuals for whom self-injury is likely to be persistent and therefore those individuals for whom early intervention may be most warranted. En ligne : http://dx.doi.org/10.1186/s11689-016-9153-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=348
in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.21[article] Persistence of self-injurious behaviour in autism spectrum disorder over 3 years: a prospective cohort study of risk markers [Texte imprimé et/ou numérique] / C. RICHARDS, Auteur ; J. MOSS, Auteur ; L. NELSON, Auteur ; C. OLIVER, Auteur . - p.21.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.21
Mots-clés : Autism spectrum disorder Hyperactivity Impulsivity Pain Prevalence Risk marker Self-injury Index. décimale : PER Périodiques Résumé : BACKGROUND: There are few studies documenting the persistence of self-injury in individuals with autism spectrum disorder (ASD) and consequently limited data on behavioural and demographic characteristics associated with persistence. In this longitudinal study, we investigated self-injury in a cohort of individuals with ASD over 3 years to identify behavioural and demographic characteristics associated with persistence. METHODS: Carers of 67 individuals with ASD (Median age of individuals with ASD in years = 13.5, Interquartile Range = 10.00-17.00), completed questionnaires relating to the presence and topography of self-injury at T1 and three years later at T2. Analyses were conducted to evaluate the persistence of self-injury and to evaluate the behavioural and demographic characteristics associated with persistence of self-injury. RESULTS: At T2 self-injurious behaviour had persisted in 77.8 % of individuals. Behavioural correlates of being non-verbal, having lower ability and higher levels of overactivity, impulsivity and repetitive behaviour, were associated with self-injury at both time points. Risk markers of impulsivity (p = 0.021) and deficits in social interaction (p = 0.026) at T1 were associated with the persistence of self-injury over 3 years. CONCLUSIONS: Impulsivity and deficits in social interaction are associated with persistent self-injury in ASD and thus may act as behavioural risk markers. The identification of these risk markers evidences a role for behaviour dysregulation in the development and maintenance of self-injury. The findings have clinical implications for proactive intervention; these behavioural characteristics may be utilised to identify 'at risk' individuals for whom self-injury is likely to be persistent and therefore those individuals for whom early intervention may be most warranted. En ligne : http://dx.doi.org/10.1186/s11689-016-9153-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=348 Persistence and predictors of self-injurious behaviour in autism: a ten-year prospective cohort study / Catherine LAVERTY in Molecular Autism, 11 (2020)
[article]
Titre : Persistence and predictors of self-injurious behaviour in autism: a ten-year prospective cohort study Type de document : Texte imprimé et/ou numérique Auteurs : Catherine LAVERTY, Auteur ; Chris OLIVER, Auteur ; Jo MOSS, Auteur ; Lisa NELSON, Auteur ; Caroline RICHARDS, Auteur Article en page(s) : 8 p. Langues : Anglais (eng) Mots-clés : Autism Impulsivity Prevalence Risk marker Self-injury Self-restraint Index. décimale : PER Périodiques Résumé : BACKGROUND: Self-injurious behaviours, such as head banging, hair pulling, skin picking and scratching, are common in individuals with autism. Despite high prevalence rates, there is a paucity of longitudinal research to refine models of risk and mechanism and inform service planning. In this longitudinal study, we investigated self-injury in a cohort of individuals with autism over 10?years to identify behavioural and demographic characteristics associated with persistent self-injury. METHODS: Carers of 67 individuals with autism completed questionnaires relating to the presence of self-injury and relevant risk markers at T (1) (mean [SD] age in years 13.4 [7.7]) and T (3) (mean [SD] age in years 23.9 [7.7]) 10?years later. Forty-six of these also took part at T (2) (3?years after initial participation). Analysis assessed demographic and behavioural risk markers for self-injury, as well as the predictive value of items assessed at T (1)and T (2.) RESULTS: Self-injury was persistent in 44% of individuals over the 10-year period, with behavioural characteristics of impulsivity (p < .001) and overactivity (p = .002), identified as risk markers for persistence. A predictive model of self-injury was derived from LASSO analysis, with baseline impulsivity, interest and pleasure, stereotyped behaviour, social communication and adaptive functioning predicting self-injury over 10?years. CONCLUSIONS: In this unique longitudinal investigation into the persistence of self-injury in a non-clinical sample of individuals with autism over a 10?year period, we have identified a novel, robust and stable profile of behavioural characteristics associated with persistent self-injury. Findings support an early intervention strategy targeted towards individuals identified to be at a higher risk of developing self-injurious behaviour. En ligne : http://dx.doi.org/10.1186/s13229-019-0307-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427
in Molecular Autism > 11 (2020) . - 8 p.[article] Persistence and predictors of self-injurious behaviour in autism: a ten-year prospective cohort study [Texte imprimé et/ou numérique] / Catherine LAVERTY, Auteur ; Chris OLIVER, Auteur ; Jo MOSS, Auteur ; Lisa NELSON, Auteur ; Caroline RICHARDS, Auteur . - 8 p.
Langues : Anglais (eng)
in Molecular Autism > 11 (2020) . - 8 p.
Mots-clés : Autism Impulsivity Prevalence Risk marker Self-injury Self-restraint Index. décimale : PER Périodiques Résumé : BACKGROUND: Self-injurious behaviours, such as head banging, hair pulling, skin picking and scratching, are common in individuals with autism. Despite high prevalence rates, there is a paucity of longitudinal research to refine models of risk and mechanism and inform service planning. In this longitudinal study, we investigated self-injury in a cohort of individuals with autism over 10?years to identify behavioural and demographic characteristics associated with persistent self-injury. METHODS: Carers of 67 individuals with autism completed questionnaires relating to the presence of self-injury and relevant risk markers at T (1) (mean [SD] age in years 13.4 [7.7]) and T (3) (mean [SD] age in years 23.9 [7.7]) 10?years later. Forty-six of these also took part at T (2) (3?years after initial participation). Analysis assessed demographic and behavioural risk markers for self-injury, as well as the predictive value of items assessed at T (1)and T (2.) RESULTS: Self-injury was persistent in 44% of individuals over the 10-year period, with behavioural characteristics of impulsivity (p < .001) and overactivity (p = .002), identified as risk markers for persistence. A predictive model of self-injury was derived from LASSO analysis, with baseline impulsivity, interest and pleasure, stereotyped behaviour, social communication and adaptive functioning predicting self-injury over 10?years. CONCLUSIONS: In this unique longitudinal investigation into the persistence of self-injury in a non-clinical sample of individuals with autism over a 10?year period, we have identified a novel, robust and stable profile of behavioural characteristics associated with persistent self-injury. Findings support an early intervention strategy targeted towards individuals identified to be at a higher risk of developing self-injurious behaviour. En ligne : http://dx.doi.org/10.1186/s13229-019-0307-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=427 What Do Repetitive and Stereotyped Movements Mean for Infant Siblings of Children with Autism Spectrum Disorders? / Cara R. DAMIANO in Journal of Autism and Developmental Disorders, 43-6 (June 2013)
[article]
Titre : What Do Repetitive and Stereotyped Movements Mean for Infant Siblings of Children with Autism Spectrum Disorders? Type de document : Texte imprimé et/ou numérique Auteurs : Cara R. DAMIANO, Auteur ; Allison S. NAHMIAS, Auteur ; Abigail L. HOGAN-BROWN, Auteur ; Wendy L. STONE, Auteur Article en page(s) : p.1326-1335 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders (ASD) Repetitive and stereotyped movements Infant siblings of children with ASD Risk marker Diagnostic outcome Index. décimale : PER Périodiques Résumé : Repetitive and stereotyped movements (RSMs) in infancy are associated with later diagnoses of autism spectrum disorder (ASD), yet this relationship has not been fully explored in high-risk populations. The current study investigated how RSMs involving object and body use are related to diagnostic outcomes in infant siblings of children with ASD (Sibs-ASD) and typically developing children (Sibs-TD). The rate and number of different types of RSMs were measured at an average of 15 months with follow-up diagnostic evaluations approximately 18 months later. While Sibs-ASD displayed higher rates of RSMs relative to Sibs-TD, rates did not differ according to diagnostic outcome in Sibs-ASD. However preliminary evidence suggests that qualitative differences in RSM type warrant further investigation as early diagnostic markers. En ligne : http://dx.doi.org/10.1007/s10803-012-1681-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201
in Journal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1326-1335[article] What Do Repetitive and Stereotyped Movements Mean for Infant Siblings of Children with Autism Spectrum Disorders? [Texte imprimé et/ou numérique] / Cara R. DAMIANO, Auteur ; Allison S. NAHMIAS, Auteur ; Abigail L. HOGAN-BROWN, Auteur ; Wendy L. STONE, Auteur . - p.1326-1335.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-6 (June 2013) . - p.1326-1335
Mots-clés : Autism spectrum disorders (ASD) Repetitive and stereotyped movements Infant siblings of children with ASD Risk marker Diagnostic outcome Index. décimale : PER Périodiques Résumé : Repetitive and stereotyped movements (RSMs) in infancy are associated with later diagnoses of autism spectrum disorder (ASD), yet this relationship has not been fully explored in high-risk populations. The current study investigated how RSMs involving object and body use are related to diagnostic outcomes in infant siblings of children with ASD (Sibs-ASD) and typically developing children (Sibs-TD). The rate and number of different types of RSMs were measured at an average of 15 months with follow-up diagnostic evaluations approximately 18 months later. While Sibs-ASD displayed higher rates of RSMs relative to Sibs-TD, rates did not differ according to diagnostic outcome in Sibs-ASD. However preliminary evidence suggests that qualitative differences in RSM type warrant further investigation as early diagnostic markers. En ligne : http://dx.doi.org/10.1007/s10803-012-1681-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=201