Characterizing the daily life, needs, and priorities of adults with autism spectrum disorder from Interactive Autism Network data / Katherine GOTHAM in Autism, 19-7 (October 2015)  

Public ISBD [article]  inAutism > 19-7 (October 2015) . - p.794-804 Titre : Characterizing the daily life, needs, and priorities of adults with autism spectrum disorder from Interactive Autism Network data Type de document : Texte imprimé et/ou numérique Auteurs : Katherine GOTHAM, Auteur ; Alison R. MARVIN, Auteur ; Julie LOUNDS TAYLOR, Auteur ; Zachary WARREN, Auteur ; Connie M. ANDERSON, Auteur ; Paul A. LAW, Auteur ; Jessica K. LAW, Auteur ; Paul H. LIPKIN, Auteur Année de publication : 2015 Article en page(s) : p.794-804 Langues : Anglais (eng) Mots-clés : adults  autism spectrum disorder  Interactive Autism Network  outcome  patient-centered outcome research Index. décimale : PER Périodiques Résumé : Using online survey data from a large sample of adults with autism spectrum disorder and legal guardians, we first report outcomes across a variety of contexts for participants with a wide range of functioning, and second, summarize these stakeholders’ priorities for future research. The sample included n?=?255 self-reporting adults with autism spectrum disorder aged 18–71?years (M?=?38.5?years, standard deviation?=?13.1?years) and n?=?143 adults with autism spectrum disorder aged 18–58?years (M?=?25.0?years, standard deviation?=?8.2?years) whose information was provided by legal guardians. Although the self-reporting subsample had much higher rates of employment, marriage/partnership, and independent living than are typically seen in autism spectrum disorder outcome studies, they remained underemployed and had strikingly high rates of comorbid disorders. Data on both descriptive outcomes and rated priorities converged across subsamples to indicate the need for more adult research on life skills, treatments, co-occurring conditions, and vocational and educational opportunities. Stakeholders also placed priority on improving public services, health care access, and above all, public acceptance of adults with autism spectrum disorder. Findings must be interpreted in light of the self-reporting subsample’s significant proportion of females and of later-diagnosed individuals. This study underscores the need for lifespan research; initiatives will benefit from incorporating information from the unique perspectives of adults with autism spectrum disorder and their families. En ligne : http://dx.doi.org/10.1177/1362361315583818 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269 [article] Characterizing the daily life, needs, and priorities of adults with autism spectrum disorder from Interactive Autism Network data [Texte imprimé et/ou numérique] / Katherine GOTHAM, Auteur ; Alison R. MARVIN, Auteur ; Julie LOUNDS TAYLOR, Auteur ; Zachary WARREN, Auteur ; Connie M. ANDERSON, Auteur ; Paul A. LAW, Auteur ; Jessica K. LAW, Auteur ; Paul H. LIPKIN, Auteur . - 2015 . - p.794-804. Langues : Anglais (eng) in Autism > 19-7 (October 2015) . - p.794-804 Mots-clés : adults  autism spectrum disorder  Interactive Autism Network  outcome  patient-centered outcome research Index. décimale : PER Périodiques Résumé : Using online survey data from a large sample of adults with autism spectrum disorder and legal guardians, we first report outcomes across a variety of contexts for participants with a wide range of functioning, and second, summarize these stakeholders’ priorities for future research. The sample included n?=?255 self-reporting adults with autism spectrum disorder aged 18–71?years (M?=?38.5?years, standard deviation?=?13.1?years) and n?=?143 adults with autism spectrum disorder aged 18–58?years (M?=?25.0?years, standard deviation?=?8.2?years) whose information was provided by legal guardians. Although the self-reporting subsample had much higher rates of employment, marriage/partnership, and independent living than are typically seen in autism spectrum disorder outcome studies, they remained underemployed and had strikingly high rates of comorbid disorders. Data on both descriptive outcomes and rated priorities converged across subsamples to indicate the need for more adult research on life skills, treatments, co-occurring conditions, and vocational and educational opportunities. Stakeholders also placed priority on improving public services, health care access, and above all, public acceptance of adults with autism spectrum disorder. Findings must be interpreted in light of the self-reporting subsample’s significant proportion of females and of later-diagnosed individuals. This study underscores the need for lifespan research; initiatives will benefit from incorporating information from the unique perspectives of adults with autism spectrum disorder and their families. En ligne : http://dx.doi.org/10.1177/1362361315583818 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269

Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the Social Responsiveness Scale-2 / Thomas W. FRAZIER in Autism, 18-1 (January 2014)  

Public ISBD [article]  inAutism > 18-1 (January 2014) . - p.31-44 Titre : Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the Social Responsiveness Scale-2 Type de document : Texte imprimé et/ou numérique Auteurs : Thomas W. FRAZIER, Auteur ; Kristin R. RATLIFF, Auteur ; Chris GRUBER, Auteur ; Yi ZHANG, Auteur ; Paul A. LAW, Auteur ; John N. CONSTANTINO, Auteur Article en page(s) : p.31-44 Langues : Anglais (eng) Mots-clés : Asperger syndrome  autism  factor structure  pervasive developmental disorder Index. décimale : PER Périodiques Résumé : Understanding the factor structure of autistic symptomatology is critical to the discovery and interpretation of causal mechanisms in autism spectrum disorder. We applied confirmatory factor analysis and assessment of measurement invariance to a large (N = 9635) accumulated collection of reports on quantitative autistic traits using the Social Responsiveness Scale, representing a broad diversity of age, severity, and reporter type. A two-factor structure (corresponding to social communication impairment and restricted, repetitive behavior) as elaborated in the updated Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) criteria for autism spectrum disorder exhibited acceptable model fit in confirmatory factor analysis. Measurement invariance was appreciable across age, sex, and reporter (self vs other), but somewhat less apparent between clinical and nonclinical populations in this sample comprised of both familial and sporadic autism spectrum disorders. The statistical power afforded by this large sample allowed relative differentiation of three factors among items encompassing social communication impairment (emotion recognition, social avoidance, and interpersonal relatedness) and two factors among items encompassing restricted, repetitive behavior (insistence on sameness and repetitive mannerisms). Cross-trait correlations remained extremely high, that is, on the order of 0.66–0.92. These data clarify domains of statistically significant factoral separation that may relate to partially—but not completely—overlapping biological mechanisms, contributing to variation in human social competency. Given such robust intercorrelations among symptom domains, understanding their co-emergence remains a high priority in conceptualizing common neural mechanisms underlying autistic syndromes. En ligne : http://dx.doi.org/10.1177/1362361313500382 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 [article] Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the Social Responsiveness Scale-2 [Texte imprimé et/ou numérique] / Thomas W. FRAZIER, Auteur ; Kristin R. RATLIFF, Auteur ; Chris GRUBER, Auteur ; Yi ZHANG, Auteur ; Paul A. LAW, Auteur ; John N. CONSTANTINO, Auteur . - p.31-44. Langues : Anglais (eng) in Autism > 18-1 (January 2014) . - p.31-44 Mots-clés : Asperger syndrome  autism  factor structure  pervasive developmental disorder Index. décimale : PER Périodiques Résumé : Understanding the factor structure of autistic symptomatology is critical to the discovery and interpretation of causal mechanisms in autism spectrum disorder. We applied confirmatory factor analysis and assessment of measurement invariance to a large (N = 9635) accumulated collection of reports on quantitative autistic traits using the Social Responsiveness Scale, representing a broad diversity of age, severity, and reporter type. A two-factor structure (corresponding to social communication impairment and restricted, repetitive behavior) as elaborated in the updated Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) criteria for autism spectrum disorder exhibited acceptable model fit in confirmatory factor analysis. Measurement invariance was appreciable across age, sex, and reporter (self vs other), but somewhat less apparent between clinical and nonclinical populations in this sample comprised of both familial and sporadic autism spectrum disorders. The statistical power afforded by this large sample allowed relative differentiation of three factors among items encompassing social communication impairment (emotion recognition, social avoidance, and interpersonal relatedness) and two factors among items encompassing restricted, repetitive behavior (insistence on sameness and repetitive mannerisms). Cross-trait correlations remained extremely high, that is, on the order of 0.66–0.92. These data clarify domains of statistically significant factoral separation that may relate to partially—but not completely—overlapping biological mechanisms, contributing to variation in human social competency. Given such robust intercorrelations among symptom domains, understanding their co-emergence remains a high priority in conceptualizing common neural mechanisms underlying autistic syndromes. En ligne : http://dx.doi.org/10.1177/1362361313500382 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221

Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey / Rebecca E. ROSENBERG in Autism Research and Treatment, (May 2011)  

Public ISBD [article]  inAutism Research and Treatment > (May 2011) . - 11 p. Titre : Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca E. ROSENBERG, Auteur ; Rebecca LANDA, Auteur ; J. Kiely LAW, Auteur ; Elizabeth A. STUART, Auteur ; Paul A. LAW, Auteur Année de publication : 2011 Article en page(s) : 11 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Entry into early intervention depends on both age of first parent concern (AOC) and age at initial autism spectrum disorder (ASD) diagnosis (AOD). Using data collected from a national online registry from 6214 children diagnosed with an ASD between 1994 and 2010 in the US, we analyzed the effect of individual, family, and geographic covariates on AOC and AOD in a multivariate linear regression model with random effects. Overall, no single modifiable factor associated with AOC or AOD emerged but cumulative variation in certain individual- and family-based features, as well as some geographic factors, all contribute to AOC and AOD variation. A multipronged strategy is needed for targeted education and awareness campaigns to maximize outcomes and decrease disparities in ASD care. En ligne : http://dx.doi.org/10.1155/2011/874619 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=141 [article] Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey [Texte imprimé et/ou numérique] / Rebecca E. ROSENBERG, Auteur ; Rebecca LANDA, Auteur ; J. Kiely LAW, Auteur ; Elizabeth A. STUART, Auteur ; Paul A. LAW, Auteur . - 2011 . - 11 p. Langues : Anglais (eng) in Autism Research and Treatment > (May 2011) . - 11 p. Index. décimale : PER Périodiques Résumé : Entry into early intervention depends on both age of first parent concern (AOC) and age at initial autism spectrum disorder (ASD) diagnosis (AOD). Using data collected from a national online registry from 6214 children diagnosed with an ASD between 1994 and 2010 in the US, we analyzed the effect of individual, family, and geographic covariates on AOC and AOD in a multivariate linear regression model with random effects. Overall, no single modifiable factor associated with AOC or AOD emerged but cumulative variation in certain individual- and family-based features, as well as some geographic factors, all contribute to AOC and AOD variation. A multipronged strategy is needed for targeted education and awareness campaigns to maximize outcomes and decrease disparities in ASD care. En ligne : http://dx.doi.org/10.1155/2011/874619 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=141

Mood Disorders in Mothers of Children on the Autism Spectrum Are Associated with Higher Functioning Autism / Roma A. VASA in Autism Research and Treatment, (July 2012)  

Public ISBD [article]  inAutism Research and Treatment > (July 2012) . - 8 p. Titre : Mood Disorders in Mothers of Children on the Autism Spectrum Are Associated with Higher Functioning Autism Type de document : Texte imprimé et/ou numérique Auteurs : Roma A. VASA, Auteur ; Connie M. ANDERSON, Auteur ; Alison MARVIN, Auteur ; Rebecca E. ROSENBERG, Auteur ; J. Kiely LAW, Auteur ; Julia THORN, Auteur ; Geeta SARPHARE, Auteur ; Paul A. LAW, Auteur Année de publication : 2012 Article en page(s) : 8 p. Langues : Anglais (eng) Mots-clés : Trouble de l'humeur Index. décimale : PER Périodiques Résumé : Mood disorders occur more frequently in family members of individuals with autism spectrum disorders (ASD) than in the general population. There may be associations between maternal mood disorder history patterns and specific ASD phenotypes. We therefore examined the relationship between maternal mood disorders and child autism spectrum disorders in 998 mother-child dyads enrolled in a national online autism registry and database. Mothers of children with ASD completed online questionnaires addressing their child’s ASD as well as their own mood disorder history. In multivariate logistic regression models of ASD diagnoses, the odds of an Asperger disorder versus autistic disorder diagnosis were higher among those children whose mothers had a lifetime history of bipolar disorder (OR 2.11, CI 1.20, 3.69) or depression (OR 1.62, CI 1.19, 2.19). Further, maternal mood disorder onset before first pregnancy was associated with higher odds (OR 2.35, CI 1.48, 3.73) of an Asperger versus autism diagnosis among this sample of children with ASD. These data suggest that differences in maternal mood disorder history may be associated with ASD phenotype in offspring. En ligne : http://dx.doi.org/10.1155/2012/435646 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=181 [article] Mood Disorders in Mothers of Children on the Autism Spectrum Are Associated with Higher Functioning Autism [Texte imprimé et/ou numérique] / Roma A. VASA, Auteur ; Connie M. ANDERSON, Auteur ; Alison MARVIN, Auteur ; Rebecca E. ROSENBERG, Auteur ; J. Kiely LAW, Auteur ; Julia THORN, Auteur ; Geeta SARPHARE, Auteur ; Paul A. LAW, Auteur . - 2012 . - 8 p. Langues : Anglais (eng) in Autism Research and Treatment > (July 2012) . - 8 p. Mots-clés : Trouble de l'humeur Index. décimale : PER Périodiques Résumé : Mood disorders occur more frequently in family members of individuals with autism spectrum disorders (ASD) than in the general population. There may be associations between maternal mood disorder history patterns and specific ASD phenotypes. We therefore examined the relationship between maternal mood disorders and child autism spectrum disorders in 998 mother-child dyads enrolled in a national online autism registry and database. Mothers of children with ASD completed online questionnaires addressing their child’s ASD as well as their own mood disorder history. In multivariate logistic regression models of ASD diagnoses, the odds of an Asperger disorder versus autistic disorder diagnosis were higher among those children whose mothers had a lifetime history of bipolar disorder (OR 2.11, CI 1.20, 3.69) or depression (OR 1.62, CI 1.19, 2.19). Further, maternal mood disorder onset before first pregnancy was associated with higher odds (OR 2.35, CI 1.48, 3.73) of an Asperger versus autism diagnosis among this sample of children with ASD. These data suggest that differences in maternal mood disorder history may be associated with ASD phenotype in offspring. En ligne : http://dx.doi.org/10.1155/2012/435646 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=181

Onset Patterns Prior to 36 Months in Autism Spectrum Disorders / Luther G. KALB in Journal of Autism and Developmental Disorders, 40-11 (November 2010)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1389-1402 Titre : Onset Patterns Prior to 36 Months in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Luther G. KALB, Auteur ; J. Kiely LAW, Auteur ; Rebecca LANDA, Auteur ; Paul A. LAW, Auteur Année de publication : 2010 Article en page(s) : p.1389-1402 Langues : Anglais (eng) Mots-clés : Autism  Pervasive developmental disorders  Regression  Symptom  Onset pattern Index. décimale : PER Périodiques Résumé : The present study investigated differences among children with three different patterns of autism symptom onset: regression, plateau, and no loss and no plateau. Cross-sectional data were collected from parents of children aged 3–17 years with an autism spectrum disorder (n = 2,720) who were recruited through a US-based online research database. Parental report of developmental characteristics was assessed through a parent questionnaire, and current autism symptoms were measured via the Social Responsiveness Scale and Social Communication Questionnaire. Multivariate analyses indicated that children with regression had a distinct developmental pattern marked by less delayed early development. However, following regression, these children evinced elevated autism symptom scores and an increased risk for poorer outcomes when compared with the other onset groups. En ligne : http://dx.doi.org/10.1007/s10803-010-0998-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114 [article] Onset Patterns Prior to 36 Months in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Luther G. KALB, Auteur ; J. Kiely LAW, Auteur ; Rebecca LANDA, Auteur ; Paul A. LAW, Auteur . - 2010 . - p.1389-1402. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 40-11 (November 2010) . - p.1389-1402 Mots-clés : Autism  Pervasive developmental disorders  Regression  Symptom  Onset pattern Index. décimale : PER Périodiques Résumé : The present study investigated differences among children with three different patterns of autism symptom onset: regression, plateau, and no loss and no plateau. Cross-sectional data were collected from parents of children aged 3–17 years with an autism spectrum disorder (n = 2,720) who were recruited through a US-based online research database. Parental report of developmental characteristics was assessed through a parent questionnaire, and current autism symptoms were measured via the Social Responsiveness Scale and Social Communication Questionnaire. Multivariate analyses indicated that children with regression had a distinct developmental pattern marked by less delayed early development. However, following regression, these children evinced elevated autism symptom scores and an increased risk for poorer outcomes when compared with the other onset groups. En ligne : http://dx.doi.org/10.1007/s10803-010-0998-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=114

Parent Report of Community Psychiatric Comorbid Diagnoses in Autism Spectrum Disorders / Rebecca E. ROSENBERG in Autism Research and Treatment, (June 2011)  

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Psychotropic Medication Use Among Children With Autism Spectrum Disorders Enrolled in a National Registry, 2007–2008 / Rebecca E. ROSENBERG in Journal of Autism and Developmental Disorders, 40-3 (March 2010)  

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Stability of Initial Autism Spectrum Disorder Diagnoses in Community Settings / Amy M. DANIELS in Journal of Autism and Developmental Disorders, 41-1 (January 2011)  

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Trends in Autism Spectrum Disorder Diagnoses: 1994–2007 / Rebecca E. ROSENBERG in Journal of Autism and Developmental Disorders, 39-8 (August 2009)  

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Verification of Parent-Report of Child Autism Spectrum Disorder Diagnosis to a Web-Based Autism Registry / Amy M. DANIELS in Journal of Autism and Developmental Disorders, 42-2 (February 2012)  

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