Language and reading abilities of children with autism spectrum disorders and specific language impairment and their first-degree relatives / Kristen A. LINDGREN in Autism Research, 2-1 (February 2009)  

Public ISBD [article]  inAutism Research > 2-1 (February 2009) . - p.22-38 Titre : Language and reading abilities of children with autism spectrum disorders and specific language impairment and their first-degree relatives Type de document : Texte imprimé et/ou numérique Auteurs : Kristen A. LINDGREN, Auteur ; Helen TAGER-FLUSBERG, Auteur ; J. Bruce TOMBLIN, Auteur ; S. E. FOLSTEIN, Auteur Année de publication : 2009 Article en page(s) : p.22-38 Langues : Anglais (eng) Mots-clés : autism-spectrum-disorder specific-language-impairment parents siblings broader-phenotype genetics language reading Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and specific language impairment (SLI) are developmental disorders exhibiting language deficits, but it is unclear whether they arise from similar etiologies. Language impairments have been described in family members of children with ASD and SLI, but few studies have quantified them. In this study, we examined IQ, language, and reading abilities of ASD and SLI children and their first-degree relatives to address whether the language difficulties observed in some children with ASD are familial and to better understand the degree of overlap between these disorders and their broader phenotypes. Participants were 52 autistic children, 36 children with SLI, their siblings, and their parents. The ASD group was divided into those with (ALI, n=32) and without (ALN, n=20) language impairment. Relationships between ASD severity and language performance were also examined in the ASD probands. ALI and SLI probands performed similarly on most measures while ALN probands scored higher. ALN and ALI probands' language scores were not related to Autism Diagnostic Interview - Revised and Autism Diagnostic Observation Schedule algorithm scores. SLI relatives scored lowest on all measures, and while scores were not in the impaired range, relatives of ALI children scored lower than relatives of ALN children on some measures, though not those showing highest heritability in SLI. Given that ALI relatives performed better than SLI relatives across the language measures, the hypothesis that ALI and SLI families share similar genetic loading for language is not strongly supported. En ligne : http://dx.doi.org/10.1002/aur.63 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=935 [article] Language and reading abilities of children with autism spectrum disorders and specific language impairment and their first-degree relatives [Texte imprimé et/ou numérique] / Kristen A. LINDGREN, Auteur ; Helen TAGER-FLUSBERG, Auteur ; J. Bruce TOMBLIN, Auteur ; S. E. FOLSTEIN, Auteur . - 2009 . - p.22-38. Langues : Anglais (eng) in Autism Research > 2-1 (February 2009) . - p.22-38 Mots-clés : autism-spectrum-disorder specific-language-impairment parents siblings broader-phenotype genetics language reading Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and specific language impairment (SLI) are developmental disorders exhibiting language deficits, but it is unclear whether they arise from similar etiologies. Language impairments have been described in family members of children with ASD and SLI, but few studies have quantified them. In this study, we examined IQ, language, and reading abilities of ASD and SLI children and their first-degree relatives to address whether the language difficulties observed in some children with ASD are familial and to better understand the degree of overlap between these disorders and their broader phenotypes. Participants were 52 autistic children, 36 children with SLI, their siblings, and their parents. The ASD group was divided into those with (ALI, n=32) and without (ALN, n=20) language impairment. Relationships between ASD severity and language performance were also examined in the ASD probands. ALI and SLI probands performed similarly on most measures while ALN probands scored higher. ALN and ALI probands' language scores were not related to Autism Diagnostic Interview - Revised and Autism Diagnostic Observation Schedule algorithm scores. SLI relatives scored lowest on all measures, and while scores were not in the impaired range, relatives of ALI children scored lower than relatives of ALN children on some measures, though not those showing highest heritability in SLI. Given that ALI relatives performed better than SLI relatives across the language measures, the hypothesis that ALI and SLI families share similar genetic loading for language is not strongly supported. En ligne : http://dx.doi.org/10.1002/aur.63 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=935

Overlap between autism and specific language impairment: comparison of Autism Diagnostic Interview and Autism Diagnostic Observation Schedule scores / Ovsanna T. LEYFER in Autism Research, 1-5 (October 2008)  

Public ISBD [article]  inAutism Research > 1-5 (October 2008) . - p.284-296 Titre : Overlap between autism and specific language impairment: comparison of Autism Diagnostic Interview and Autism Diagnostic Observation Schedule scores Type de document : Texte imprimé et/ou numérique Auteurs : Ovsanna T. LEYFER, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Michael DOWD, Auteur ; J. Bruce TOMBLIN, Auteur ; S. E. FOLSTEIN, Auteur Année de publication : 2008 Article en page(s) : p.284-296 Langues : Anglais (eng) Mots-clés : autism specific-language-impairment developmental-disorders etiology Autism-Diagnostic-Interview-Revised Autism-Diagnostic-Observation-Schedule Index. décimale : PER Périodiques Résumé : Autism and specific language impairment (SLI) are developmental disorders that, although distinct by definition, have in common some features of both language and social behavior. The goal of this study was to further explore the extent to which specific clinical features of autism are seen in SLI. The children with the two disorders, matched for non-verbal IQ, were compared on the Autism Diagnostic Interview - Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS). In the SLI group, 41% met autism or autism spectrum cut-offs for social or communication domains either on the ADI or ADOS or both. No relationship was found between the language deficits exhibited by the children with SLI and their scores on the ADI and ADOS. These findings contribute to evidence that there is some overlap in social and communicative deficits between autism and SLI, supporting the view that autism and SLI share etiologic factors. This continuum of pathology between SLI and autism appears to range from structural language abnormalities as seen in individuals with SLI to individuals with SLI with both structural and social abnormalities to individuals with autism with pragmatic impairment and language abnormalities. En ligne : http://dx.doi.org/10.1002/aur.43 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=933 [article] Overlap between autism and specific language impairment: comparison of Autism Diagnostic Interview and Autism Diagnostic Observation Schedule scores [Texte imprimé et/ou numérique] / Ovsanna T. LEYFER, Auteur ; Helen TAGER-FLUSBERG, Auteur ; Michael DOWD, Auteur ; J. Bruce TOMBLIN, Auteur ; S. E. FOLSTEIN, Auteur . - 2008 . - p.284-296. Langues : Anglais (eng) in Autism Research > 1-5 (October 2008) . - p.284-296 Mots-clés : autism specific-language-impairment developmental-disorders etiology Autism-Diagnostic-Interview-Revised Autism-Diagnostic-Observation-Schedule Index. décimale : PER Périodiques Résumé : Autism and specific language impairment (SLI) are developmental disorders that, although distinct by definition, have in common some features of both language and social behavior. The goal of this study was to further explore the extent to which specific clinical features of autism are seen in SLI. The children with the two disorders, matched for non-verbal IQ, were compared on the Autism Diagnostic Interview - Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS). In the SLI group, 41% met autism or autism spectrum cut-offs for social or communication domains either on the ADI or ADOS or both. No relationship was found between the language deficits exhibited by the children with SLI and their scores on the ADI and ADOS. These findings contribute to evidence that there is some overlap in social and communicative deficits between autism and SLI, supporting the view that autism and SLI share etiologic factors. This continuum of pathology between SLI and autism appears to range from structural language abnormalities as seen in individuals with SLI to individuals with SLI with both structural and social abnormalities to individuals with autism with pragmatic impairment and language abnormalities. En ligne : http://dx.doi.org/10.1002/aur.43 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=933

Specific Language Impairment / J. Bruce TOMBLIN

Public ISBD in Autism Spectrum Disorders / David G. AMARAL Titre : Specific Language Impairment Type de document : Texte imprimé et/ou numérique Auteurs : J. Bruce TOMBLIN, Auteur ; Karla MCGREGOR, Auteur ; Allison F. BEAN, Auteur Année de publication : 2011 Importance : p.315-329 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 in Autism Spectrum Disorders / David G. AMARAL Specific Language Impairment [Texte imprimé et/ou numérique] / J. Bruce TOMBLIN, Auteur ; Karla MCGREGOR, Auteur ; Allison F. BEAN, Auteur . - 2011 . - p.315-329. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139

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