Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison / K. A. PEDERSEN in Journal of Autism and Developmental Disorders, 48-11 (November 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3658-3667 Titre : Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison Type de document : Texte imprimé et/ou numérique Auteurs : K. A. PEDERSEN, Auteur ; Susan L. SANTANGELO, Auteur ; R. L. GABRIELS, Auteur ; G. RIGHI, Auteur ; M. ERARD, Auteur ; M. SIEGEL, Auteur Article en page(s) : p.3658-3667 Langues : Anglais (eng) Mots-clés : Autism inpatient collection (AIC)  Autism spectrum disorder (ASD)  Crisis  Externalizing problem behaviors  Psychiatric inpatients  Self-injurious behavior  Tantrum-like behavior Index. décimale : PER Périodiques Résumé : Psychiatric hospitalization of children with autism spectrum disorder (ASD) is relatively common and occurs at a higher rate than in non-ASD youth. This study compared changes in the severity of serious problem behaviors in 350 youth with ASD enrolled in the autism inpatient collection during and after hospitalization in six specialized child psychiatry units. There was a significant reduction in serious problem behaviors from admission (aberrant behavior checklist-irritability subscale M = 29.7, SD 9.6) to discharge (M = 15.0, SD 10.3) and 2-month follow-up (M = 19.3, SD 10.3). Between discharge and 2-month follow-up, tantrum-like behaviors but not self-injurious behaviors increased slightly. Improvement in the severity of problem behaviors was not uniform across sites, even after controlling for measured site differences. En ligne : http://dx.doi.org/10.1007/s10803-017-3366-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370 [article] Behavioral Outcomes of Specialized Psychiatric Hospitalization in the Autism Inpatient Collection (AIC): A Multisite Comparison [Texte imprimé et/ou numérique] / K. A. PEDERSEN, Auteur ; Susan L. SANTANGELO, Auteur ; R. L. GABRIELS, Auteur ; G. RIGHI, Auteur ; M. ERARD, Auteur ; M. SIEGEL, Auteur . - p.3658-3667. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-11 (November 2018) . - p.3658-3667 Mots-clés : Autism inpatient collection (AIC)  Autism spectrum disorder (ASD)  Crisis  Externalizing problem behaviors  Psychiatric inpatients  Self-injurious behavior  Tantrum-like behavior Index. décimale : PER Périodiques Résumé : Psychiatric hospitalization of children with autism spectrum disorder (ASD) is relatively common and occurs at a higher rate than in non-ASD youth. This study compared changes in the severity of serious problem behaviors in 350 youth with ASD enrolled in the autism inpatient collection during and after hospitalization in six specialized child psychiatry units. There was a significant reduction in serious problem behaviors from admission (aberrant behavior checklist-irritability subscale M = 29.7, SD 9.6) to discharge (M = 15.0, SD 10.3) and 2-month follow-up (M = 19.3, SD 10.3). Between discharge and 2-month follow-up, tantrum-like behaviors but not self-injurious behaviors increased slightly. Improvement in the severity of problem behaviors was not uniform across sites, even after controlling for measured site differences. En ligne : http://dx.doi.org/10.1007/s10803-017-3366-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=370

Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population / Elise B. ROBINSON in Journal of Autism and Developmental Disorders, 41-12 (December 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1733-1737 Titre : Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population Type de document : Texte imprimé et/ou numérique Auteurs : Elise B. ROBINSON, Auteur ; Kerim M. MUNIR, Auteur ; Marie C. MCCORMICK, Auteur ; Karestan C. KOENEN, Auteur ; Susan L. SANTANGELO, Auteur Année de publication : 2011 Article en page(s) : p.1733-1737 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Autistic traits  Parental age  ALSPAC Index. décimale : PER Périodiques Résumé : This is the first investigation of the relationship between parental age and extreme social-communicative autistic traits in the general population. The parents of 5,246 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) completed the Social and Communication Disorders Checklist (SCDC). The association between parental age and SCDC scores was assessed in the full sample and among high scoring individuals (e.g. top 5%, 1%). There was no association between parental age and social-communicative autistic traits in the general population. Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively. En ligne : http://dx.doi.org/10.1007/s10803-011-1202-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148 [article] Brief Report: No Association Between Parental Age and Extreme Social-Communicative Autistic Traits in the General Population [Texte imprimé et/ou numérique] / Elise B. ROBINSON, Auteur ; Kerim M. MUNIR, Auteur ; Marie C. MCCORMICK, Auteur ; Karestan C. KOENEN, Auteur ; Susan L. SANTANGELO, Auteur . - 2011 . - p.1733-1737. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-12 (December 2011) . - p.1733-1737 Mots-clés : Autism spectrum disorders  Autistic traits  Parental age  ALSPAC Index. décimale : PER Périodiques Résumé : This is the first investigation of the relationship between parental age and extreme social-communicative autistic traits in the general population. The parents of 5,246 children in the Avon Longitudinal Study of Parents and Children (ALSPAC) completed the Social and Communication Disorders Checklist (SCDC). The association between parental age and SCDC scores was assessed in the full sample and among high scoring individuals (e.g. top 5%, 1%). There was no association between parental age and social-communicative autistic traits in the general population. Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively. En ligne : http://dx.doi.org/10.1007/s10803-011-1202-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=148

Erratum to: Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II / Kristen LYALL in Journal of Autism and Developmental Disorders, 41-5 (May 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.628 Titre : Erratum to: Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur Année de publication : 2011 Article en page(s) : p.628 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-010-1097-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Erratum to: Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur . - 2011 . - p.628. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.628 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-010-1097-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

Increased resting-state thalamocortical functional connectivity in children and young adults with autism spectrum disorder / Quynh Trang Huong NGUYEN ; Dimitrios MYLONAS ; Susan L. SANTANGELO ; Dara S. MANOACH in Autism Research, 16-2 (February 2023)  

Public ISBD [article]  inAutism Research > 16-2 (February 2023) . - p.271-279 Titre : Increased resting-state thalamocortical functional connectivity in children and young adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Quynh Trang Huong NGUYEN, Auteur ; Dimitrios MYLONAS, Auteur ; Susan L. SANTANGELO, Auteur ; Dara S. MANOACH, Auteur Article en page(s) : p.271-279 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract There is converging evidence that abnormal thalamocortical interactions contribute to attention deficits and sensory sensitivities in autism spectrum disorder (ASD). However, previous functional MRI studies of thalamocortical connectivity in ASD have produced inconsistent findings in terms of both the direction (hyper vs. hypoconnectivity) and location of group differences. This may reflect, in part, the confounding effects of head motion during scans. In the present study, we investigated resting-state thalamocortical functional connectivity in 8-25â€year-olds with ASD and their typically developing (TD) peers. We used pre-scan training, on-line motion correction, and rigorous data quality assurance protocols to minimize motion confounds. ASD participants showed increased thalamic connectivity with temporal cortex relative to TD. Both groups showed similar age-related decreases in thalamic connectivity with occipital cortex, consistent with a process of circuit refinement. Findings of thalamocortical hyperconnectivity in ASD are consistent with other evidence that decreased thalamic inhibition leads to increase and less filtered sensory information reaching the cortex where it disrupts attention and contributes to sensory sensitivity. This literature motivates studies of mechanisms, functional consequences, and treatment of thalamocortical circuit dysfunction in ASD. En ligne : https://doi.org/10.1002/aur.2875 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495 [article] Increased resting-state thalamocortical functional connectivity in children and young adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Quynh Trang Huong NGUYEN, Auteur ; Dimitrios MYLONAS, Auteur ; Susan L. SANTANGELO, Auteur ; Dara S. MANOACH, Auteur . - p.271-279. Langues : Anglais (eng) in Autism Research > 16-2 (February 2023) . - p.271-279 Index. décimale : PER Périodiques Résumé : Abstract There is converging evidence that abnormal thalamocortical interactions contribute to attention deficits and sensory sensitivities in autism spectrum disorder (ASD). However, previous functional MRI studies of thalamocortical connectivity in ASD have produced inconsistent findings in terms of both the direction (hyper vs. hypoconnectivity) and location of group differences. This may reflect, in part, the confounding effects of head motion during scans. In the present study, we investigated resting-state thalamocortical functional connectivity in 8-25â€year-olds with ASD and their typically developing (TD) peers. We used pre-scan training, on-line motion correction, and rigorous data quality assurance protocols to minimize motion confounds. ASD participants showed increased thalamic connectivity with temporal cortex relative to TD. Both groups showed similar age-related decreases in thalamic connectivity with occipital cortex, consistent with a process of circuit refinement. Findings of thalamocortical hyperconnectivity in ASD are consistent with other evidence that decreased thalamic inhibition leads to increase and less filtered sensory information reaching the cortex where it disrupts attention and contributes to sensory sensitivity. This literature motivates studies of mechanisms, functional consequences, and treatment of thalamocortical circuit dysfunction in ASD. En ligne : https://doi.org/10.1002/aur.2875 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495

Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II / Kristen LYALL in Journal of Autism and Developmental Disorders, 41-5 (May 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.618-627 Titre : Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II Type de document : Texte imprimé et/ou numérique Auteurs : Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur Année de publication : 2011 Article en page(s) : p.618-627 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Reproductive risk factors  Hormonal factors Index. décimale : PER Périodiques Résumé : It is not known whether reproductive factors early in the mother’s life influence risk of autism spectrum disorders (ASD). We assessed maternal age at menarche, menstrual cycle characteristics during adolescence, oral contraceptive use prior to first birth, body shape, and body mass index (BMI) in association with ASD using binomial regression in a cohort study of 61,596 women, including 743 cases. Overall, early life factors were not associated with ASD, though early age at menarche (RR for age 10 or less = 1.54, 95% CI 1.18, 2.02, p = 0.0002) and BMI at age 18 of ≥30 (RR 2.03, 95% CI 1.34, 3.08, p = 0.0008) were significantly associated with increased risk of ASD. Further work should investigate the potential influence of these factors. En ligne : http://dx.doi.org/10.1007/s10803-010-1079-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II [Texte imprimé et/ou numérique] / Kristen LYALL, Auteur ; David L. PAULS, Auteur ; Susan L. SANTANGELO, Auteur ; Donna SPIEGELMAN, Auteur ; Alberto ASCHERIO, Auteur . - 2011 . - p.618-627. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.618-627 Mots-clés : Autism spectrum disorders  Reproductive risk factors  Hormonal factors Index. décimale : PER Périodiques Résumé : It is not known whether reproductive factors early in the mother’s life influence risk of autism spectrum disorders (ASD). We assessed maternal age at menarche, menstrual cycle characteristics during adolescence, oral contraceptive use prior to first birth, body shape, and body mass index (BMI) in association with ASD using binomial regression in a cohort study of 61,596 women, including 743 cases. Overall, early life factors were not associated with ASD, though early age at menarche (RR for age 10 or less = 1.54, 95% CI 1.18, 2.02, p = 0.0002) and BMI at age 18 of ≥30 (RR 2.03, 95% CI 1.34, 3.08, p = 0.0008) were significantly associated with increased risk of ASD. Further work should investigate the potential influence of these factors. En ligne : http://dx.doi.org/10.1007/s10803-010-1079-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

Paternal age increases the risk for autism in an Iranian population sample / Roksana SASANFAR in Molecular Autism, (February 2010)  

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Predictors of Cognitive Test Patterns in Autism Families / S. E. FOLSTEIN in Journal of Child Psychology and Psychiatry, 40-7 (October 1999)

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Pregnancy complications and obstetric suboptimality in association with autism spectrum disorders in children of the nurses' health study II / Kristen LYALL in Autism Research, 5-1 (February 2012)  

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The autism inpatient collection: methods and preliminary sample description / Matthew SIEGEL in Molecular Autism, (November 2015)  

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