[article]
| Titre : |
Resting-State Oscillatory Activity in Autism Spectrum Disorders |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Lauren CORNEW, Auteur ; Timothy P.L. ROBERTS, Auteur ; Lisa BLASKEY, Auteur ; J. Christopher EDGAR, Auteur |
| Année de publication : |
2012 |
| Article en page(s) : |
p.1884-1894 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism Magnetoencephalography Resting-state Oscillations Alpha Gamma |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Neural oscillatory anomalies in autism spectrum disorders (ASD) suggest an excitatory/inhibitory imbalance; however, the nature and clinical relevance of these anomalies are unclear. Whole-cortex magnetoencephalography data were collected while 50 children (27 with ASD, 23 controls) underwent an eyes-closed resting-state exam. A Fast Fourier Transform was applied and oscillatory activity examined from 1 to 120 Hz at 15 regional sources. Associations between oscillatory anomalies and symptom severity were probed. Children with ASD exhibited regionally specific elevations in delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), and high frequency (20–120 Hz) power, supporting an imbalance of neural excitation/inhibition as a neurobiological feature of ASD. Increased temporal and parietal alpha power was associated with greater symptom severity and thus is of particular interest. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-011-1431-6 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 |
in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1884-1894
[article] Resting-State Oscillatory Activity in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Lauren CORNEW, Auteur ; Timothy P.L. ROBERTS, Auteur ; Lisa BLASKEY, Auteur ; J. Christopher EDGAR, Auteur . - 2012 . - p.1884-1894. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1884-1894
| Mots-clés : |
Autism Magnetoencephalography Resting-state Oscillations Alpha Gamma |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Neural oscillatory anomalies in autism spectrum disorders (ASD) suggest an excitatory/inhibitory imbalance; however, the nature and clinical relevance of these anomalies are unclear. Whole-cortex magnetoencephalography data were collected while 50 children (27 with ASD, 23 controls) underwent an eyes-closed resting-state exam. A Fast Fourier Transform was applied and oscillatory activity examined from 1 to 120 Hz at 15 regional sources. Associations between oscillatory anomalies and symptom severity were probed. Children with ASD exhibited regionally specific elevations in delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), and high frequency (20–120 Hz) power, supporting an imbalance of neural excitation/inhibition as a neurobiological feature of ASD. Increased temporal and parietal alpha power was associated with greater symptom severity and thus is of particular interest. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-011-1431-6 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 |
|  |
Resting-State Oscillatory Activity in Autism Spectrum Disorders in Journal of Autism and Developmental Disorders, 42-9 (September 2012)
