14 recherche sur le mot-clé 'Resting-state'

Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume / J. Christopher EDGAR in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.795-804 Titre : Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume Type de document : Texte imprimé et/ou numérique Auteurs : J. Christopher EDGAR, Auteur ; Kory HEIKEN, Auteur ; Yu-Han CHEN, Auteur ; John D. HERRINGTON, Auteur ; Vivian CHOW, Auteur ; Song LIU, Auteur ; Luke BLOY, Auteur ; Mingxiong HUANG, Auteur ; Juhi PANDEY, Auteur ; Katelyn M. CANNON, Auteur ; Saba QASMIEH, Auteur ; Susan E. LEVY, Auteur ; Robert T. SCHULTZ, Auteur ; Timothy P L. ROBERTS, Auteur Article en page(s) : p.795-804 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Alpha  Resting-state  Magnetoencephalography  Thalamus Index. décimale : PER Périodiques Résumé : Alpha circuits (8–12 Hz), necessary for basic and complex brain processes, are abnormal in autism spectrum disorder (ASD). The present study obtained estimates of resting-state (RS) alpha activity in children with ASD and examined associations between alpha activity, age, and clinical symptoms. Given that the thalamus modulates cortical RS alpha rhythms, associations between thalamic structure and alpha activity were examined. RS magnetoencephalography was obtained from 47 typically-developing children (TDC) and 41 children with ASD. RS alpha activity was measured using distributed source localization. Left and right thalamic volume measurements were also obtained. In both groups, the strongest alpha activity was observed in Calcarine Sulcus regions. In Calcarine regions, only TDC showed the expected association between age and alpha peak frequency. ASD had more alpha activity than TDC in regions bordering the Central Sulcus as well as parietal association cortices. In ASD, whereas greater left Central Sulcus relative alpha activity was associated with higher Social Responsiveness Scale (SRS) scores, greater Calcarine region relative alpha activity was associated with lower SRS scores. Although thalamic volume group differences were not observed, relationships between thalamic volume and Calcarine alpha power were unique to TDC. The present study also identified a failure to shift peak alpha frequency as a function of age in primary alpha-generating areas in children with ASD. Findings suggested that increased RS alpha activity in primary motor and somatosensory as well as parietal multimodal areas—with increased alpha thought to reflect greater inhibition—might impair the ability to identify or interpret social cues. Finally, to our knowledge, this is the first study to report associations between thalamic volume and alpha power, an association observed only in TDC. The lack of thalamic and alpha associations in ASD suggests thalamic contributions to RS alpha abnormalities in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2236-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume [Texte imprimé et/ou numérique] / J. Christopher EDGAR, Auteur ; Kory HEIKEN, Auteur ; Yu-Han CHEN, Auteur ; John D. HERRINGTON, Auteur ; Vivian CHOW, Auteur ; Song LIU, Auteur ; Luke BLOY, Auteur ; Mingxiong HUANG, Auteur ; Juhi PANDEY, Auteur ; Katelyn M. CANNON, Auteur ; Saba QASMIEH, Auteur ; Susan E. LEVY, Auteur ; Robert T. SCHULTZ, Auteur ; Timothy P L. ROBERTS, Auteur . - p.795-804. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.795-804 Mots-clés : Autism spectrum disorder  Alpha  Resting-state  Magnetoencephalography  Thalamus Index. décimale : PER Périodiques Résumé : Alpha circuits (8–12 Hz), necessary for basic and complex brain processes, are abnormal in autism spectrum disorder (ASD). The present study obtained estimates of resting-state (RS) alpha activity in children with ASD and examined associations between alpha activity, age, and clinical symptoms. Given that the thalamus modulates cortical RS alpha rhythms, associations between thalamic structure and alpha activity were examined. RS magnetoencephalography was obtained from 47 typically-developing children (TDC) and 41 children with ASD. RS alpha activity was measured using distributed source localization. Left and right thalamic volume measurements were also obtained. In both groups, the strongest alpha activity was observed in Calcarine Sulcus regions. In Calcarine regions, only TDC showed the expected association between age and alpha peak frequency. ASD had more alpha activity than TDC in regions bordering the Central Sulcus as well as parietal association cortices. In ASD, whereas greater left Central Sulcus relative alpha activity was associated with higher Social Responsiveness Scale (SRS) scores, greater Calcarine region relative alpha activity was associated with lower SRS scores. Although thalamic volume group differences were not observed, relationships between thalamic volume and Calcarine alpha power were unique to TDC. The present study also identified a failure to shift peak alpha frequency as a function of age in primary alpha-generating areas in children with ASD. Findings suggested that increased RS alpha activity in primary motor and somatosensory as well as parietal multimodal areas—with increased alpha thought to reflect greater inhibition—might impair the ability to identify or interpret social cues. Finally, to our knowledge, this is the first study to report associations between thalamic volume and alpha power, an association observed only in TDC. The lack of thalamic and alpha associations in ASD suggests thalamic contributions to RS alpha abnormalities in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2236-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Resting-State Neurophysiological Activity Patterns in Young People with ASD, ADHD, and ASD + ADHD / E. SHEPHARD in Journal of Autism and Developmental Disorders, 48-1 (January 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-1 (January 2018) . - p.110-122 Titre : Resting-State Neurophysiological Activity Patterns in Young People with ASD, ADHD, and ASD + ADHD Type de document : Texte imprimé et/ou numérique Auteurs : E. SHEPHARD, Auteur ; C. TYE, Auteur ; Karen L. ASHWOOD, Auteur ; Bahare AZADI, Auteur ; Philip ASHERSON, Auteur ; Patrick BOLTON, Auteur ; G. MCLOUGHLIN, Auteur Article en page(s) : p.110-122 Langues : Anglais (eng) Mots-clés : Adhd  Asd  Co-occurring ASD + ADHD  Eeg  Resting-state  Spectral power Index. décimale : PER Périodiques Résumé : Altered power of resting-state neurophysiological activity has been associated with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), which commonly co-occur. We compared resting-state neurophysiological power in children with ASD, ADHD, co-occurring ASD + ADHD, and typically developing controls. Children with ASD (ASD/ASD + ADHD) showed reduced theta and alpha power compared to children without ASD (controls/ADHD). Children with ADHD (ADHD/ASD + ADHD) displayed decreased delta power compared to children without ADHD (ASD/controls). Children with ASD + ADHD largely presented as an additive co-occurrence with deficits of both disorders, although reduced theta compared to ADHD-only and reduced delta compared to controls suggested some unique markers. Identifying specific neurophysiological profiles in ASD and ADHD may assist in characterising more homogeneous subgroups to inform treatment approaches and aetiological investigations. En ligne : https://doi.org/10.1007/s10803-017-3300-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=336 [article] Resting-State Neurophysiological Activity Patterns in Young People with ASD, ADHD, and ASD + ADHD [Texte imprimé et/ou numérique] / E. SHEPHARD, Auteur ; C. TYE, Auteur ; Karen L. ASHWOOD, Auteur ; Bahare AZADI, Auteur ; Philip ASHERSON, Auteur ; Patrick BOLTON, Auteur ; G. MCLOUGHLIN, Auteur . - p.110-122. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-1 (January 2018) . - p.110-122 Mots-clés : Adhd  Asd  Co-occurring ASD + ADHD  Eeg  Resting-state  Spectral power Index. décimale : PER Périodiques Résumé : Altered power of resting-state neurophysiological activity has been associated with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), which commonly co-occur. We compared resting-state neurophysiological power in children with ASD, ADHD, co-occurring ASD + ADHD, and typically developing controls. Children with ASD (ASD/ASD + ADHD) showed reduced theta and alpha power compared to children without ASD (controls/ADHD). Children with ADHD (ADHD/ASD + ADHD) displayed decreased delta power compared to children without ADHD (ASD/controls). Children with ASD + ADHD largely presented as an additive co-occurrence with deficits of both disorders, although reduced theta compared to ADHD-only and reduced delta compared to controls suggested some unique markers. Identifying specific neurophysiological profiles in ASD and ADHD may assist in characterising more homogeneous subgroups to inform treatment approaches and aetiological investigations. En ligne : https://doi.org/10.1007/s10803-017-3300-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=336

Resting-State Oscillatory Activity in Autism Spectrum Disorders / Lauren CORNEW in Journal of Autism and Developmental Disorders, 42-9 (September 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1884-1894 Titre : Resting-State Oscillatory Activity in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Lauren CORNEW, Auteur ; Timothy P.L. ROBERTS, Auteur ; Lisa BLASKEY, Auteur ; J. Christopher EDGAR, Auteur Année de publication : 2012 Article en page(s) : p.1884-1894 Langues : Anglais (eng) Mots-clés : Autism  Magnetoencephalography  Resting-state  Oscillations  Alpha  Gamma Index. décimale : PER Périodiques Résumé : Neural oscillatory anomalies in autism spectrum disorders (ASD) suggest an excitatory/inhibitory imbalance; however, the nature and clinical relevance of these anomalies are unclear. Whole-cortex magnetoencephalography data were collected while 50 children (27 with ASD, 23 controls) underwent an eyes-closed resting-state exam. A Fast Fourier Transform was applied and oscillatory activity examined from 1 to 120 Hz at 15 regional sources. Associations between oscillatory anomalies and symptom severity were probed. Children with ASD exhibited regionally specific elevations in delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), and high frequency (20–120 Hz) power, supporting an imbalance of neural excitation/inhibition as a neurobiological feature of ASD. Increased temporal and parietal alpha power was associated with greater symptom severity and thus is of particular interest. En ligne : http://dx.doi.org/10.1007/s10803-011-1431-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 [article] Resting-State Oscillatory Activity in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Lauren CORNEW, Auteur ; Timothy P.L. ROBERTS, Auteur ; Lisa BLASKEY, Auteur ; J. Christopher EDGAR, Auteur . - 2012 . - p.1884-1894. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1884-1894 Mots-clés : Autism  Magnetoencephalography  Resting-state  Oscillations  Alpha  Gamma Index. décimale : PER Périodiques Résumé : Neural oscillatory anomalies in autism spectrum disorders (ASD) suggest an excitatory/inhibitory imbalance; however, the nature and clinical relevance of these anomalies are unclear. Whole-cortex magnetoencephalography data were collected while 50 children (27 with ASD, 23 controls) underwent an eyes-closed resting-state exam. A Fast Fourier Transform was applied and oscillatory activity examined from 1 to 120 Hz at 15 regional sources. Associations between oscillatory anomalies and symptom severity were probed. Children with ASD exhibited regionally specific elevations in delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), and high frequency (20–120 Hz) power, supporting an imbalance of neural excitation/inhibition as a neurobiological feature of ASD. Increased temporal and parietal alpha power was associated with greater symptom severity and thus is of particular interest. En ligne : http://dx.doi.org/10.1007/s10803-011-1431-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180

Aberrant resting-state functional connectivity in limbic and salience networks in treatment-naïve clinically depressed adolescents / Justine Nienke PANNEKOEK in Journal of Child Psychology and Psychiatry, 55-12 (December 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-12 (December 2014) . - p.1317-1327 Titre : Aberrant resting-state functional connectivity in limbic and salience networks in treatment-naïve clinically depressed adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Justine Nienke PANNEKOEK, Auteur ; S. J. A. VAN DER WERFF, Auteur ; Paul H. F. MEENS, Auteur ; Bianca G. VAN DEN BULK, Auteur ; Dietsje D. JOLLES, Auteur ; Ilya M. VEER, Auteur ; Natasja D. J. VAN LANG, Auteur ; Serge A. R. B. ROMBOUTS, Auteur ; Nic J. A. VAN DER WEE, Auteur ; Robert R. J. M. VERMEIREN, Auteur Article en page(s) : p.1317-1327 Langues : Anglais (eng) Mots-clés : Resting-state  adolescents  depression  anxiety Index. décimale : PER Périodiques Résumé : Background Depression is prevalent and typically has its onset in adolescence. Resting-state fMRI could help create a better understanding of the underlying neurobiological mechanisms during this critical period. In this study, resting-state functional connectivity (RSFC) is examined using seed regions-of-interest (ROIs) associated with three networks: the limbic network, the default mode network (DMN) and the salience network. Methods Twenty-six treatment-naïve, clinically depressed adolescents of whom 18 had comorbid anxiety, and 26 pair-wise matched healthy controls underwent resting-state fMRI. The three networks were investigated using a seed-based ROI approach with seeds in the bilateral amygdala (limbic network), bilateral dorsal anterior cingulate cortex (dACC; salience network) and bilateral posterior cingulate cortex (default mode network). Results Compared to healthy controls, clinically depressed adolescents showed increased RSFC of the left amygdala with right parietal cortical areas, and decreased right amygdala RSFC with left frontal cortical areas including the ACC, as well as with right occipito-parietal areas. The bilateral dACC showed decreased RSFC with the right middle frontal gyrus, frontal pole, and inferior frontal gyrus in clinically depressed adolescents. No abnormalities in DMN RSFC were found, and differences in RSFC did not correlate with clinical measures. Conclusions The aberrant RSFC of the amygdala network and the dACC network may be related to altered emotion processing and regulation in depressed adolescents. Our results provide new insights into RSFC in clinically depressed adolescents and future models on adolescent depression may include abnormalities in the connectivity of salience network. En ligne : http://dx.doi.org/10.1111/jcpp.12266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243 [article] Aberrant resting-state functional connectivity in limbic and salience networks in treatment-naïve clinically depressed adolescents [Texte imprimé et/ou numérique] / Justine Nienke PANNEKOEK, Auteur ; S. J. A. VAN DER WERFF, Auteur ; Paul H. F. MEENS, Auteur ; Bianca G. VAN DEN BULK, Auteur ; Dietsje D. JOLLES, Auteur ; Ilya M. VEER, Auteur ; Natasja D. J. VAN LANG, Auteur ; Serge A. R. B. ROMBOUTS, Auteur ; Nic J. A. VAN DER WEE, Auteur ; Robert R. J. M. VERMEIREN, Auteur . - p.1317-1327. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-12 (December 2014) . - p.1317-1327 Mots-clés : Resting-state  adolescents  depression  anxiety Index. décimale : PER Périodiques Résumé : Background Depression is prevalent and typically has its onset in adolescence. Resting-state fMRI could help create a better understanding of the underlying neurobiological mechanisms during this critical period. In this study, resting-state functional connectivity (RSFC) is examined using seed regions-of-interest (ROIs) associated with three networks: the limbic network, the default mode network (DMN) and the salience network. Methods Twenty-six treatment-naïve, clinically depressed adolescents of whom 18 had comorbid anxiety, and 26 pair-wise matched healthy controls underwent resting-state fMRI. The three networks were investigated using a seed-based ROI approach with seeds in the bilateral amygdala (limbic network), bilateral dorsal anterior cingulate cortex (dACC; salience network) and bilateral posterior cingulate cortex (default mode network). Results Compared to healthy controls, clinically depressed adolescents showed increased RSFC of the left amygdala with right parietal cortical areas, and decreased right amygdala RSFC with left frontal cortical areas including the ACC, as well as with right occipito-parietal areas. The bilateral dACC showed decreased RSFC with the right middle frontal gyrus, frontal pole, and inferior frontal gyrus in clinically depressed adolescents. No abnormalities in DMN RSFC were found, and differences in RSFC did not correlate with clinical measures. Conclusions The aberrant RSFC of the amygdala network and the dACC network may be related to altered emotion processing and regulation in depressed adolescents. Our results provide new insights into RSFC in clinically depressed adolescents and future models on adolescent depression may include abnormalities in the connectivity of salience network. En ligne : http://dx.doi.org/10.1111/jcpp.12266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=243

Preliminary examination of the effects of an early parenting intervention on amygdala-orbitofrontal cortex resting-state functional connectivity among high-risk children: A randomized clinical trial / Marta KOROM ; Emilio A. VALADEZ ; Nim TOTTENHAM ; Mary DOZIER ; Jeffrey M. Spielberg in Development and Psychopathology, 37-1 (February 2025)  

Public ISBD [article]  inDevelopment and Psychopathology > 37-1 (February 2025) . - p.384-392 Titre : Preliminary examination of the effects of an early parenting intervention on amygdala-orbitofrontal cortex resting-state functional connectivity among high-risk children: A randomized clinical trial : Development and Psychopathology Type de document : Texte imprimé et/ou numérique Auteurs : Marta KOROM, Auteur ; Emilio A. VALADEZ, Auteur ; Nim TOTTENHAM, Auteur ; Mary DOZIER, Auteur ; Jeffrey M. Spielberg, Auteur Article en page(s) : p.384-392 Langues : Anglais (eng) Mots-clés : Parenting intervention  adversity  amygdala?OFC functional connectivity  emotion regulation  imaging  resting-state Index. décimale : PER Périodiques Résumé : We examined the long-term causal effects of an evidence-based parenting program delivered in infancy on children?s emotion regulation and resting-state functional connectivity (rs-fc) during middle childhood. Families were referred to the study by Child Protective Services (CPS) as part of a diversion from a foster care program. A low-risk group of families was also recruited. CPS-involved families were randomly assigned to receive the target (Attachment and Biobehavioral Catch-up, ABC) or a control intervention (Developmental Education for Families, DEF) before infants turned 2. Both interventions were home-based, manualized, and 10-sessions long. During middle childhood, children underwent a 6-min resting-state functional MRI scan. Amygdala seed-based rs-fc analysis was completed with intervention group as the group-level predictor of interest. Fifty-seven children (NABC = 21; NDEF = 17; NCOMP = 19; Mage = 10.02 years, range = 8.08-12.14) were scanned successfully. The DEF group evidenced negative left amygdala?OFC connectivity, whereas connectivity was near zero in the ABC and comparison groups (ABCvsDEF: Cohen?s d = 1.17). ABC may enhance high-risk children?s regulatory neurobiology outcomes ?8 years after the intervention was completed. En ligne : https://dx.doi.org/10.1017/S0954579423001669 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Preliminary examination of the effects of an early parenting intervention on amygdala-orbitofrontal cortex resting-state functional connectivity among high-risk children: A randomized clinical trial : Development and Psychopathology [Texte imprimé et/ou numérique] / Marta KOROM, Auteur ; Emilio A. VALADEZ, Auteur ; Nim TOTTENHAM, Auteur ; Mary DOZIER, Auteur ; Jeffrey M. Spielberg, Auteur . - p.384-392. Langues : Anglais (eng) in Development and Psychopathology > 37-1 (February 2025) . - p.384-392 Mots-clés : Parenting intervention  adversity  amygdala?OFC functional connectivity  emotion regulation  imaging  resting-state Index. décimale : PER Périodiques Résumé : We examined the long-term causal effects of an evidence-based parenting program delivered in infancy on children?s emotion regulation and resting-state functional connectivity (rs-fc) during middle childhood. Families were referred to the study by Child Protective Services (CPS) as part of a diversion from a foster care program. A low-risk group of families was also recruited. CPS-involved families were randomly assigned to receive the target (Attachment and Biobehavioral Catch-up, ABC) or a control intervention (Developmental Education for Families, DEF) before infants turned 2. Both interventions were home-based, manualized, and 10-sessions long. During middle childhood, children underwent a 6-min resting-state functional MRI scan. Amygdala seed-based rs-fc analysis was completed with intervention group as the group-level predictor of interest. Fifty-seven children (NABC = 21; NDEF = 17; NCOMP = 19; Mage = 10.02 years, range = 8.08-12.14) were scanned successfully. The DEF group evidenced negative left amygdala?OFC connectivity, whereas connectivity was near zero in the ABC and comparison groups (ABCvsDEF: Cohen?s d = 1.17). ABC may enhance high-risk children?s regulatory neurobiology outcomes ?8 years after the intervention was completed. En ligne : https://dx.doi.org/10.1017/S0954579423001669 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

ADHD-related sex differences in fronto-subcortical intrinsic functional connectivity and associations with delay discounting / K. S. ROSCH in Journal of Neurodevelopmental Disorders, 10-1 (December 2018)  

Permalink

Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest / Sonja SIMPRAGA in Autism, 25-5 (July 2021)  

Permalink

Adults with autism spectrum disorder show atypical patterns of thoughts and feelings during rest / Sonja SIMPRAGA in Autism, 26-5 (July 2022)  

Permalink

Decreased homotopic interhemispheric functional connectivity in children with autism spectrum disorder / S. YAO in Autism Research, 14-8 (August 2021)  

Permalink

Generalizability and reproducibility of functional connectivity in autism / J. B. KING in Molecular Autism, 10 (2019)  

Permalink