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Résultat de la recherche
8 recherche sur le mot-clé 'Alpha'




Alpha connectivity and inhibitory control in adults with autism spectrum disorder / Veronica YUK in Molecular Autism, 11 (2020)
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Titre : Alpha connectivity and inhibitory control in adults with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Veronica YUK, Auteur ; Benjamin T. DUNKLEY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Margot J. TAYLOR, Auteur Langues : Anglais (eng) Mots-clés : Alpha Autism Connectivity Go/No-go Inhibition Meg Index. décimale : PER Périodiques Résumé : BACKGROUND: Individuals with autism spectrum disorder (ASD) often report difficulties with inhibition in everyday life. During inhibition tasks, adults with ASD show reduced activation of and connectivity between brain areas implicated in inhibition, suggesting impairments in inhibitory control at the neural level. Our study further investigated these differences by using magnetoencephalography (MEG) to examine the frequency band(s) in which functional connectivity underlying response inhibition occurs, as brain functions are frequency specific, and whether connectivity in certain frequency bands differs between adults with and without ASD. METHODS: We analysed MEG data from 40 adults with ASD (27 males; 26.94?±?6.08 years old) and 39 control adults (27 males; 27.29?±?5.94 years old) who performed a Go/No-go task. The task involved two blocks with different proportions of No-go trials: Inhibition (25% No-go) and Vigilance (75% No-go). We compared whole-brain connectivity in the two groups during correct No-go trials in the Inhibition vs. Vigilance blocks between 0 and 400 ms. RESULTS: Despite comparable performance on the Go/No-go task, adults with ASD showed reduced connectivity compared to controls in the alpha band (8-14 Hz) in a network with a main hub in the right inferior frontal gyrus. Decreased connectivity in this network predicted more self-reported difficulties on a measure of inhibition in everyday life. LIMITATIONS: Measures of everyday inhibitory control were not available for all participants, so this relationship between reduced network connectivity and inhibitory control abilities may not be necessarily representative of all adults with ASD or the larger ASD population. Further research with independent samples of adults with ASD, including those with a wider range of cognitive abilities, would be valuable. CONCLUSIONS: Our findings demonstrate reduced functional brain connectivity during response inhibition in adults with ASD. As alpha-band synchrony has been linked to top-down control mechanisms, we propose that the lack of alpha synchrony observed in our ASD group may reflect difficulties in suppressing task-irrelevant information, interfering with inhibition in real-life situations. En ligne : http://dx.doi.org/10.1186/s13229-020-00400-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438
in Molecular Autism > 11 (2020)[article] Alpha connectivity and inhibitory control in adults with autism spectrum disorder [Texte imprimé et/ou numérique] / Veronica YUK, Auteur ; Benjamin T. DUNKLEY, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Margot J. TAYLOR, Auteur.
Langues : Anglais (eng)
in Molecular Autism > 11 (2020)
Mots-clés : Alpha Autism Connectivity Go/No-go Inhibition Meg Index. décimale : PER Périodiques Résumé : BACKGROUND: Individuals with autism spectrum disorder (ASD) often report difficulties with inhibition in everyday life. During inhibition tasks, adults with ASD show reduced activation of and connectivity between brain areas implicated in inhibition, suggesting impairments in inhibitory control at the neural level. Our study further investigated these differences by using magnetoencephalography (MEG) to examine the frequency band(s) in which functional connectivity underlying response inhibition occurs, as brain functions are frequency specific, and whether connectivity in certain frequency bands differs between adults with and without ASD. METHODS: We analysed MEG data from 40 adults with ASD (27 males; 26.94?±?6.08 years old) and 39 control adults (27 males; 27.29?±?5.94 years old) who performed a Go/No-go task. The task involved two blocks with different proportions of No-go trials: Inhibition (25% No-go) and Vigilance (75% No-go). We compared whole-brain connectivity in the two groups during correct No-go trials in the Inhibition vs. Vigilance blocks between 0 and 400 ms. RESULTS: Despite comparable performance on the Go/No-go task, adults with ASD showed reduced connectivity compared to controls in the alpha band (8-14 Hz) in a network with a main hub in the right inferior frontal gyrus. Decreased connectivity in this network predicted more self-reported difficulties on a measure of inhibition in everyday life. LIMITATIONS: Measures of everyday inhibitory control were not available for all participants, so this relationship between reduced network connectivity and inhibitory control abilities may not be necessarily representative of all adults with ASD or the larger ASD population. Further research with independent samples of adults with ASD, including those with a wider range of cognitive abilities, would be valuable. CONCLUSIONS: Our findings demonstrate reduced functional brain connectivity during response inhibition in adults with ASD. As alpha-band synchrony has been linked to top-down control mechanisms, we propose that the lack of alpha synchrony observed in our ASD group may reflect difficulties in suppressing task-irrelevant information, interfering with inhibition in real-life situations. En ligne : http://dx.doi.org/10.1186/s13229-020-00400-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438 Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume / J. Christopher EDGAR in Journal of Autism and Developmental Disorders, 45-3 (March 2015)
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Titre : Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume Type de document : Texte imprimé et/ou numérique Auteurs : J. Christopher EDGAR, Auteur ; Kory HEIKEN, Auteur ; Yu-Han CHEN, Auteur ; John D. HERRINGTON, Auteur ; Vivian CHOW, Auteur ; Song LIU, Auteur ; Luke BLOY, Auteur ; Mingxiong HUANG, Auteur ; Juhi PANDEY, Auteur ; Katelyn M. CANNON, Auteur ; Saba QASMIEH, Auteur ; Susan E. LEVY, Auteur ; Robert T. SCHULTZ, Auteur ; Timothy P L. ROBERTS, Auteur Article en page(s) : p.795-804 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Alpha Resting-state Magnetoencephalography Thalamus Index. décimale : PER Périodiques Résumé : Alpha circuits (8–12 Hz), necessary for basic and complex brain processes, are abnormal in autism spectrum disorder (ASD). The present study obtained estimates of resting-state (RS) alpha activity in children with ASD and examined associations between alpha activity, age, and clinical symptoms. Given that the thalamus modulates cortical RS alpha rhythms, associations between thalamic structure and alpha activity were examined. RS magnetoencephalography was obtained from 47 typically-developing children (TDC) and 41 children with ASD. RS alpha activity was measured using distributed source localization. Left and right thalamic volume measurements were also obtained. In both groups, the strongest alpha activity was observed in Calcarine Sulcus regions. In Calcarine regions, only TDC showed the expected association between age and alpha peak frequency. ASD had more alpha activity than TDC in regions bordering the Central Sulcus as well as parietal association cortices. In ASD, whereas greater left Central Sulcus relative alpha activity was associated with higher Social Responsiveness Scale (SRS) scores, greater Calcarine region relative alpha activity was associated with lower SRS scores. Although thalamic volume group differences were not observed, relationships between thalamic volume and Calcarine alpha power were unique to TDC. The present study also identified a failure to shift peak alpha frequency as a function of age in primary alpha-generating areas in children with ASD. Findings suggested that increased RS alpha activity in primary motor and somatosensory as well as parietal multimodal areas—with increased alpha thought to reflect greater inhibition—might impair the ability to identify or interpret social cues. Finally, to our knowledge, this is the first study to report associations between thalamic volume and alpha power, an association observed only in TDC. The lack of thalamic and alpha associations in ASD suggests thalamic contributions to RS alpha abnormalities in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2236-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258
in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.795-804[article] Resting-State Alpha in Autism Spectrum Disorder and Alpha Associations with Thalamic Volume [Texte imprimé et/ou numérique] / J. Christopher EDGAR, Auteur ; Kory HEIKEN, Auteur ; Yu-Han CHEN, Auteur ; John D. HERRINGTON, Auteur ; Vivian CHOW, Auteur ; Song LIU, Auteur ; Luke BLOY, Auteur ; Mingxiong HUANG, Auteur ; Juhi PANDEY, Auteur ; Katelyn M. CANNON, Auteur ; Saba QASMIEH, Auteur ; Susan E. LEVY, Auteur ; Robert T. SCHULTZ, Auteur ; Timothy P L. ROBERTS, Auteur . - p.795-804.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.795-804
Mots-clés : Autism spectrum disorder Alpha Resting-state Magnetoencephalography Thalamus Index. décimale : PER Périodiques Résumé : Alpha circuits (8–12 Hz), necessary for basic and complex brain processes, are abnormal in autism spectrum disorder (ASD). The present study obtained estimates of resting-state (RS) alpha activity in children with ASD and examined associations between alpha activity, age, and clinical symptoms. Given that the thalamus modulates cortical RS alpha rhythms, associations between thalamic structure and alpha activity were examined. RS magnetoencephalography was obtained from 47 typically-developing children (TDC) and 41 children with ASD. RS alpha activity was measured using distributed source localization. Left and right thalamic volume measurements were also obtained. In both groups, the strongest alpha activity was observed in Calcarine Sulcus regions. In Calcarine regions, only TDC showed the expected association between age and alpha peak frequency. ASD had more alpha activity than TDC in regions bordering the Central Sulcus as well as parietal association cortices. In ASD, whereas greater left Central Sulcus relative alpha activity was associated with higher Social Responsiveness Scale (SRS) scores, greater Calcarine region relative alpha activity was associated with lower SRS scores. Although thalamic volume group differences were not observed, relationships between thalamic volume and Calcarine alpha power were unique to TDC. The present study also identified a failure to shift peak alpha frequency as a function of age in primary alpha-generating areas in children with ASD. Findings suggested that increased RS alpha activity in primary motor and somatosensory as well as parietal multimodal areas—with increased alpha thought to reflect greater inhibition—might impair the ability to identify or interpret social cues. Finally, to our knowledge, this is the first study to report associations between thalamic volume and alpha power, an association observed only in TDC. The lack of thalamic and alpha associations in ASD suggests thalamic contributions to RS alpha abnormalities in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2236-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume / Scott O. MURRAY ; Daniela L. Seczon ; Mark Pettet ; Hannah M. REA ; Kristin M. WOODARD ; Tamar KOLODNY ; Sara Jane WEBB in Autism Research, 18-1 (January 2025)
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Titre : Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Scott O. MURRAY, Auteur ; Daniela L. Seczon, Auteur ; Mark Pettet, Auteur ; Hannah M. REA, Auteur ; Kristin M. WOODARD, Auteur ; Tamar KOLODNY, Auteur ; Sara Jane WEBB, Auteur Article en page(s) : p.56-69 Langues : Anglais (eng) Mots-clés : alpha autism spectrum disorder EEG sensory processing vision Index. décimale : PER Périodiques Résumé : Abstract Alpha-band (~10?Hz) neural oscillations, crucial for gating sensory information, may offer insights into the atypical sensory experiences characteristic of autism spectrum disorder (ASD). We investigated alpha-band EEG activity in autistic adults (n?=?29) compared with a nonautistic group (n?=?23) under various stimulus-driven and resting-state conditions. The autistic group showed consistently higher alpha amplitude across all time points. In addition, there was proportionally more suppression of alpha at stimulus onset in the autistic group, and alpha amplitude in this stimulus-onset period correlated with sensory behaviors. Recent research suggests a link between subcortical structures' volume and cortical alpha magnitude. Prompted by this, we explored the association between alpha power and the volume of subcortical structures and total cortical volume in ASD. Our findings indicate a significant correlation with total cortical volume and a group by hippocampal volume interaction, pointing to the potential role of anatomical structural characteristics as potential modulators of cortical alpha oscillations in ASD. Overall, the results highlight altered alpha in autistic individuals as potentially contributing to the heightened sensory symptoms in autistic compared with nonautistic adults. En ligne : https://doi.org/10.1002/aur.3266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546
in Autism Research > 18-1 (January 2025) . - p.56-69[article] Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume : Autism Research [Texte imprimé et/ou numérique] / Scott O. MURRAY, Auteur ; Daniela L. Seczon, Auteur ; Mark Pettet, Auteur ; Hannah M. REA, Auteur ; Kristin M. WOODARD, Auteur ; Tamar KOLODNY, Auteur ; Sara Jane WEBB, Auteur . - p.56-69.
Langues : Anglais (eng)
in Autism Research > 18-1 (January 2025) . - p.56-69
Mots-clés : alpha autism spectrum disorder EEG sensory processing vision Index. décimale : PER Périodiques Résumé : Abstract Alpha-band (~10?Hz) neural oscillations, crucial for gating sensory information, may offer insights into the atypical sensory experiences characteristic of autism spectrum disorder (ASD). We investigated alpha-band EEG activity in autistic adults (n?=?29) compared with a nonautistic group (n?=?23) under various stimulus-driven and resting-state conditions. The autistic group showed consistently higher alpha amplitude across all time points. In addition, there was proportionally more suppression of alpha at stimulus onset in the autistic group, and alpha amplitude in this stimulus-onset period correlated with sensory behaviors. Recent research suggests a link between subcortical structures' volume and cortical alpha magnitude. Prompted by this, we explored the association between alpha power and the volume of subcortical structures and total cortical volume in ASD. Our findings indicate a significant correlation with total cortical volume and a group by hippocampal volume interaction, pointing to the potential role of anatomical structural characteristics as potential modulators of cortical alpha oscillations in ASD. Overall, the results highlight altered alpha in autistic individuals as potentially contributing to the heightened sensory symptoms in autistic compared with nonautistic adults. En ligne : https://doi.org/10.1002/aur.3266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 Peak Alpha Frequency and Thalamic Structure in Children with Typical Development and Autism Spectrum Disorder / H. L. GREEN in Journal of Autism and Developmental Disorders, 52-1 (January 2022)
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Titre : Peak Alpha Frequency and Thalamic Structure in Children with Typical Development and Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : H. L. GREEN, Auteur ; M. DIPIERO, Auteur ; S. KOPPERS, Auteur ; Jeffrey I. BERMAN, Auteur ; Luke BLOY, Auteur ; S. LIU, Auteur ; E. MCBRIDE, Auteur ; M. KU, Auteur ; Lisa BLASKEY, Auteur ; E. KUSCHNER, Auteur ; M. AIREY, Auteur ; M. KIM, Auteur ; K. KONKA, Auteur ; T. P. L. ROBERTS, Auteur ; J. C. EDGAR, Auteur Article en page(s) : p.103-112 Langues : Anglais (eng) Mots-clés : Adolescent Autism Spectrum Disorder Brain Child Humans Magnetic Resonance Imaging Male Thalamus/diagnostic imaging Alpha Autism spectrum disorder Magnetoencephalography Maturation Resting-state Thalamic volume Index. décimale : PER Périodiques Résumé : Associations between age, resting-state (RS) peak-alpha-frequency (PAF?=?frequency showing largest amplitude alpha activity), and thalamic volume (thalamus thought to modulate alpha activity) were examined to understand differences in RS alpha activity between children with autism spectrum disorder (ASD) and typically-developing children (TDC) noted in prior studies. RS MEG and structural-MRI data were obtained from 51 ASD and 70 TDC 6- to 18-year-old males. PAF and thalamic volume maturation were observed in TDC but not ASD. Although PAF was associated with right thalamic volume in TDC (R(2)?=?0.12, p?=?0.01) but not ASD (R(2)?=?0.01, p?=?0.35), this group difference was not large enough to reach significance. Findings thus showed unusual maturation of brain function and structure in ASD as well as an across-group thalamic contribution to alpha rhythms. En ligne : http://dx.doi.org/10.1007/s10803-021-04926-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.103-112[article] Peak Alpha Frequency and Thalamic Structure in Children with Typical Development and Autism Spectrum Disorder [Texte imprimé et/ou numérique] / H. L. GREEN, Auteur ; M. DIPIERO, Auteur ; S. KOPPERS, Auteur ; Jeffrey I. BERMAN, Auteur ; Luke BLOY, Auteur ; S. LIU, Auteur ; E. MCBRIDE, Auteur ; M. KU, Auteur ; Lisa BLASKEY, Auteur ; E. KUSCHNER, Auteur ; M. AIREY, Auteur ; M. KIM, Auteur ; K. KONKA, Auteur ; T. P. L. ROBERTS, Auteur ; J. C. EDGAR, Auteur . - p.103-112.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-1 (January 2022) . - p.103-112
Mots-clés : Adolescent Autism Spectrum Disorder Brain Child Humans Magnetic Resonance Imaging Male Thalamus/diagnostic imaging Alpha Autism spectrum disorder Magnetoencephalography Maturation Resting-state Thalamic volume Index. décimale : PER Périodiques Résumé : Associations between age, resting-state (RS) peak-alpha-frequency (PAF?=?frequency showing largest amplitude alpha activity), and thalamic volume (thalamus thought to modulate alpha activity) were examined to understand differences in RS alpha activity between children with autism spectrum disorder (ASD) and typically-developing children (TDC) noted in prior studies. RS MEG and structural-MRI data were obtained from 51 ASD and 70 TDC 6- to 18-year-old males. PAF and thalamic volume maturation were observed in TDC but not ASD. Although PAF was associated with right thalamic volume in TDC (R(2)?=?0.12, p?=?0.01) but not ASD (R(2)?=?0.01, p?=?0.35), this group difference was not large enough to reach significance. Findings thus showed unusual maturation of brain function and structure in ASD as well as an across-group thalamic contribution to alpha rhythms. En ligne : http://dx.doi.org/10.1007/s10803-021-04926-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 Chronic oxytocin improves neural decoupling at rest in children with autism: an exploratory RCT / Matthijs MOERKERKE ; Nicky DANIELS ; Qianqian ZHANG ; Ricchiuti GRAZIA ; Jean STEYAERT ; Jellina PRINSEN ; Bart BOETS in Journal of Child Psychology and Psychiatry, 65-10 (October 2024)
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Titre : Chronic oxytocin improves neural decoupling at rest in children with autism: an exploratory RCT Type de document : Texte imprimé et/ou numérique Auteurs : Matthijs MOERKERKE, Auteur ; Nicky DANIELS, Auteur ; Qianqian ZHANG, Auteur ; Ricchiuti GRAZIA, Auteur ; Jean STEYAERT, Auteur ; Jellina PRINSEN, Auteur ; Bart BOETS, Auteur Article en page(s) : p.1311-1326 Langues : Anglais (eng) Mots-clés : Oxytocin autism spectrum disorder electroencephalography heart rate variability neural rhythms alpha theta signal to noise Index. décimale : PER Périodiques Résumé : Background Shifts in peak frequencies of oscillatory neural rhythms are put forward as a principal mechanism by which cross-frequency coupling/decoupling is implemented in the brain. During active neural processing, functional integration is facilitated through transitory formations of ?harmonic? cross-frequency couplings, whereas ?nonharmonic? decoupling among neural oscillatory rhythms is postulated to characterize the resting, default state of the brain, minimizing the occurrence of spurious, noisy, background couplings. Methods Within this exploratory, randomized, placebo-controlled trial, we assessed whether the transient occurrence of nonharmonic and harmonic relationships between peak-frequencies in the alpha (8?14?Hz) and theta (4?8?Hz) bands is impacted by intranasal administration of oxytocin, a neuromodulator implicated in improving homeostasis and reducing stress/anxiety. To do so, resting-state electroencephalography was acquired before and after 4?weeks of oxytocin administration (12?IU twice-daily) in children with autism spectrum disorder (8?12?years, n?=?33 oxytocin; n?=?34 placebo). At the baseline, neural assessments of children with autism were compared with those of a matched cohort of children without autism (n?=?40). Results Compared to nonautistic peers, autistic children displayed a lower incidence of nonharmonic alpha-theta cross-frequency decoupling, indicating a higher incidence of spurious ?noisy? coupling in their resting brain (p?=?.001). Dimensionally, increased neural coupling was associated with more social difficulties (p?=?.002) and lower activity of the parasympathetic ?rest & digest? branch of the autonomic nervous system (p?=?.018), indexed with high-frequency heart-rate-variability. Notably, after oxytocin administration, the transient formation of nonharmonic cross-frequency configurations was increased in the cohort of autistic children (p?.001), indicating a beneficial effect of oxytocin on reducing spurious cross-frequency-interactions. Furthermore, parallel epigenetics changes of the oxytocin receptor gene indicated that the neural effects were likely mediated by changes in endogenous oxytocinergic signaling (p?=?.006). Conclusions Chronic oxytocin induced important homeostatic changes in the resting-state intrinsic neural frequency architecture, reflective of reduced noisy oscillatory couplings and improved signal-to-noise properties. En ligne : https://doi.org/10.1111/jcpp.13966 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535
in Journal of Child Psychology and Psychiatry > 65-10 (October 2024) . - p.1311-1326[article] Chronic oxytocin improves neural decoupling at rest in children with autism: an exploratory RCT [Texte imprimé et/ou numérique] / Matthijs MOERKERKE, Auteur ; Nicky DANIELS, Auteur ; Qianqian ZHANG, Auteur ; Ricchiuti GRAZIA, Auteur ; Jean STEYAERT, Auteur ; Jellina PRINSEN, Auteur ; Bart BOETS, Auteur . - p.1311-1326.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 65-10 (October 2024) . - p.1311-1326
Mots-clés : Oxytocin autism spectrum disorder electroencephalography heart rate variability neural rhythms alpha theta signal to noise Index. décimale : PER Périodiques Résumé : Background Shifts in peak frequencies of oscillatory neural rhythms are put forward as a principal mechanism by which cross-frequency coupling/decoupling is implemented in the brain. During active neural processing, functional integration is facilitated through transitory formations of ?harmonic? cross-frequency couplings, whereas ?nonharmonic? decoupling among neural oscillatory rhythms is postulated to characterize the resting, default state of the brain, minimizing the occurrence of spurious, noisy, background couplings. Methods Within this exploratory, randomized, placebo-controlled trial, we assessed whether the transient occurrence of nonharmonic and harmonic relationships between peak-frequencies in the alpha (8?14?Hz) and theta (4?8?Hz) bands is impacted by intranasal administration of oxytocin, a neuromodulator implicated in improving homeostasis and reducing stress/anxiety. To do so, resting-state electroencephalography was acquired before and after 4?weeks of oxytocin administration (12?IU twice-daily) in children with autism spectrum disorder (8?12?years, n?=?33 oxytocin; n?=?34 placebo). At the baseline, neural assessments of children with autism were compared with those of a matched cohort of children without autism (n?=?40). Results Compared to nonautistic peers, autistic children displayed a lower incidence of nonharmonic alpha-theta cross-frequency decoupling, indicating a higher incidence of spurious ?noisy? coupling in their resting brain (p?=?.001). Dimensionally, increased neural coupling was associated with more social difficulties (p?=?.002) and lower activity of the parasympathetic ?rest & digest? branch of the autonomic nervous system (p?=?.018), indexed with high-frequency heart-rate-variability. Notably, after oxytocin administration, the transient formation of nonharmonic cross-frequency configurations was increased in the cohort of autistic children (p?.001), indicating a beneficial effect of oxytocin on reducing spurious cross-frequency-interactions. Furthermore, parallel epigenetics changes of the oxytocin receptor gene indicated that the neural effects were likely mediated by changes in endogenous oxytocinergic signaling (p?=?.006). Conclusions Chronic oxytocin induced important homeostatic changes in the resting-state intrinsic neural frequency architecture, reflective of reduced noisy oscillatory couplings and improved signal-to-noise properties. En ligne : https://doi.org/10.1111/jcpp.13966 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=535 EEG hyper-connectivity in high-risk infants is associated with later autism / Elena V. OREKHOVA in Journal of Neurodevelopmental Disorders, 6-1 (December 2014)
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PermalinkEvidence of a faster posterior dominant EEG rhythm in children with autism / Michael D. GREGORY in Research in Autism Spectrum Disorders, 6-3 (July-September 2012)
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PermalinkResting-State Oscillatory Activity in Autism Spectrum Disorders / Lauren CORNEW in Journal of Autism and Developmental Disorders, 42-9 (September 2012)
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