3 recherche sur le mot-clé 'Oscillations'

Aberrant oscillatory activity in neurofibromatosis type 1: an EEG study of resting state and working memory / Samantha J. BOOTH in Journal of Neurodevelopmental Disorders, 15 (2023)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 15 (2023) Titre : Aberrant oscillatory activity in neurofibromatosis type 1: an EEG study of resting state and working memory Type de document : texte imprimé Auteurs : Samantha J. BOOTH, Auteur ; Shruti GARG, Auteur ; Laura J.E. BROWN, Auteur ; Jonathan GREEN, Auteur ; Gorana POBRIC, Auteur ; Jason R. TAYLOR, Auteur Langues : Anglais (eng) Mots-clés : Adolescent  Female  Humans  Cognition  Cognitive Dysfunction/etiology  Electroencephalography  Memory, Short-Term  Neurofibromatosis 1/complications  Male  Electroencephalography (EEG)  Neurofibromatosis type 1 (NF1)  Oscillations  Oscillatory power  Phase coherence  Working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Neurofibromatosis type 1 (NF1) is a genetic neurodevelopmental disorder commonly associated with impaired cognitive function. Despite the well-explored functional roles of neural oscillations in neurotypical populations, only a limited number of studies have investigated oscillatory activity in the NF1 population. METHODS: We compared oscillatory spectral power and theta phase coherence in a paediatric sample with NF1 (N = 16; mean age: 13.03 years; female: n = 7) to an age/sex-matched typically developing control group (N = 16; mean age: 13.34 years; female: n = 7) using electroencephalography measured during rest and during working memory task performance. RESULTS: Relative to typically developing children, the NF1 group displayed higher resting state slow wave power and a lower peak alpha frequency. Moreover, higher theta power and frontoparietal theta phase coherence were observed in the NF1 group during working memory task performance, but these differences disappeared when controlling for baseline (resting state) activity. CONCLUSIONS: Overall, results suggest that NF1 is characterised by aberrant resting state oscillatory activity that may contribute towards the cognitive impairments experienced in this population. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03310996 (first posted: October 16, 2017). En ligne : https://dx.doi.org/10.1186/s11689-023-09492-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575 [article] Aberrant oscillatory activity in neurofibromatosis type 1: an EEG study of resting state and working memory [texte imprimé] / Samantha J. BOOTH, Auteur ; Shruti GARG, Auteur ; Laura J.E. BROWN, Auteur ; Jonathan GREEN, Auteur ; Gorana POBRIC, Auteur ; Jason R. TAYLOR, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 15 (2023) Mots-clés : Adolescent  Female  Humans  Cognition  Cognitive Dysfunction/etiology  Electroencephalography  Memory, Short-Term  Neurofibromatosis 1/complications  Male  Electroencephalography (EEG)  Neurofibromatosis type 1 (NF1)  Oscillations  Oscillatory power  Phase coherence  Working memory Index. décimale : PER Périodiques Résumé : BACKGROUND: Neurofibromatosis type 1 (NF1) is a genetic neurodevelopmental disorder commonly associated with impaired cognitive function. Despite the well-explored functional roles of neural oscillations in neurotypical populations, only a limited number of studies have investigated oscillatory activity in the NF1 population. METHODS: We compared oscillatory spectral power and theta phase coherence in a paediatric sample with NF1 (N = 16; mean age: 13.03 years; female: n = 7) to an age/sex-matched typically developing control group (N = 16; mean age: 13.34 years; female: n = 7) using electroencephalography measured during rest and during working memory task performance. RESULTS: Relative to typically developing children, the NF1 group displayed higher resting state slow wave power and a lower peak alpha frequency. Moreover, higher theta power and frontoparietal theta phase coherence were observed in the NF1 group during working memory task performance, but these differences disappeared when controlling for baseline (resting state) activity. CONCLUSIONS: Overall, results suggest that NF1 is characterised by aberrant resting state oscillatory activity that may contribute towards the cognitive impairments experienced in this population. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03310996 (first posted: October 16, 2017). En ligne : https://dx.doi.org/10.1186/s11689-023-09492-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575

Resting-State Oscillatory Activity in Autism Spectrum Disorders / Lauren CORNEW in Journal of Autism and Developmental Disorders, 42-9 (September 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1884-1894 Titre : Resting-State Oscillatory Activity in Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Lauren CORNEW, Auteur ; Timothy P.L. ROBERTS, Auteur ; Lisa BLASKEY, Auteur ; J. Christopher EDGAR, Auteur Année de publication : 2012 Article en page(s) : p.1884-1894 Langues : Anglais (eng) Mots-clés : Autism  Magnetoencephalography  Resting-state  Oscillations  Alpha  Gamma Index. décimale : PER Périodiques Résumé : Neural oscillatory anomalies in autism spectrum disorders (ASD) suggest an excitatory/inhibitory imbalance; however, the nature and clinical relevance of these anomalies are unclear. Whole-cortex magnetoencephalography data were collected while 50 children (27 with ASD, 23 controls) underwent an eyes-closed resting-state exam. A Fast Fourier Transform was applied and oscillatory activity examined from 1 to 120 Hz at 15 regional sources. Associations between oscillatory anomalies and symptom severity were probed. Children with ASD exhibited regionally specific elevations in delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), and high frequency (20–120 Hz) power, supporting an imbalance of neural excitation/inhibition as a neurobiological feature of ASD. Increased temporal and parietal alpha power was associated with greater symptom severity and thus is of particular interest. En ligne : http://dx.doi.org/10.1007/s10803-011-1431-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 [article] Resting-State Oscillatory Activity in Autism Spectrum Disorders [texte imprimé] / Lauren CORNEW, Auteur ; Timothy P.L. ROBERTS, Auteur ; Lisa BLASKEY, Auteur ; J. Christopher EDGAR, Auteur . - 2012 . - p.1884-1894. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.1884-1894 Mots-clés : Autism  Magnetoencephalography  Resting-state  Oscillations  Alpha  Gamma Index. décimale : PER Périodiques Résumé : Neural oscillatory anomalies in autism spectrum disorders (ASD) suggest an excitatory/inhibitory imbalance; however, the nature and clinical relevance of these anomalies are unclear. Whole-cortex magnetoencephalography data were collected while 50 children (27 with ASD, 23 controls) underwent an eyes-closed resting-state exam. A Fast Fourier Transform was applied and oscillatory activity examined from 1 to 120 Hz at 15 regional sources. Associations between oscillatory anomalies and symptom severity were probed. Children with ASD exhibited regionally specific elevations in delta (1–4 Hz), theta (4–8 Hz), alpha (8–12 Hz), and high frequency (20–120 Hz) power, supporting an imbalance of neural excitation/inhibition as a neurobiological feature of ASD. Increased temporal and parietal alpha power was associated with greater symptom severity and thus is of particular interest. En ligne : http://dx.doi.org/10.1007/s10803-011-1431-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180

Susceptibility to Distraction in Autism Spectrum Disorder: Probing the Integrity of Oscillatory Alpha-Band Suppression Mechanisms / Jeremy W. MURPHY in Autism Research, 7-4 (August 2014)  

Public ISBD [article]  inAutism Research > 7-4 (August 2014) . - p.442-458 Titre : Susceptibility to Distraction in Autism Spectrum Disorder: Probing the Integrity of Oscillatory Alpha-Band Suppression Mechanisms Type de document : texte imprimé Auteurs : Jeremy W. MURPHY, Auteur ; John J. FOXE, Auteur ; Joanna B. PETERS, Auteur ; Sophie MOLHOLM, Auteur Année de publication : 2014 Article en page(s) : p.442-458 Langues : Anglais (eng) Mots-clés : autism  EEG  oscillations  attention Index. décimale : PER Périodiques Résumé : When attention is directed to one information stream over another, the brain can be configured in advance to selectively process the relevant stream and suppress potentially distracting inputs. One key mechanism of suppression is through the deployment of anticipatory alpha-band (∼10 Hz) oscillatory activity, with greater alpha-band power observed in cortical regions that will ultimately process the distracting stream. Atypical attention has been implicated in autism spectrum disorder (ASD), including greater interference by distracting task-irrelevant inputs. Here we tested the integrity of these alpha-band mechanisms in ASD using an intersensory attention task. Electroencephalography (EEG) was recorded while participants were cued on a trial-by-trial basis to selectively deploy attention to the visual or auditory modality in anticipation of a target within the cued modality. Whereas typically developing (TD) children showed the predicted alpha-band modulation, with increased alpha-band power over parieto-occipital scalp when attention was deployed to the auditory compared with the visual modality, this differential pattern was entirely absent at the group level in the ASD cohort. Further, only the ASD group showed impaired performance due to the presence of task-irrelevant sensory information. These data suggest that impaired modulation of alpha-band activity plays a role in increased distraction from extraneous sensory inputs in ASD. En ligne : http://dx.doi.org/10.1002/aur.1374 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Susceptibility to Distraction in Autism Spectrum Disorder: Probing the Integrity of Oscillatory Alpha-Band Suppression Mechanisms [texte imprimé] / Jeremy W. MURPHY, Auteur ; John J. FOXE, Auteur ; Joanna B. PETERS, Auteur ; Sophie MOLHOLM, Auteur . - 2014 . - p.442-458. Langues : Anglais (eng) in Autism Research > 7-4 (August 2014) . - p.442-458 Mots-clés : autism  EEG  oscillations  attention Index. décimale : PER Périodiques Résumé : When attention is directed to one information stream over another, the brain can be configured in advance to selectively process the relevant stream and suppress potentially distracting inputs. One key mechanism of suppression is through the deployment of anticipatory alpha-band (∼10 Hz) oscillatory activity, with greater alpha-band power observed in cortical regions that will ultimately process the distracting stream. Atypical attention has been implicated in autism spectrum disorder (ASD), including greater interference by distracting task-irrelevant inputs. Here we tested the integrity of these alpha-band mechanisms in ASD using an intersensory attention task. Electroencephalography (EEG) was recorded while participants were cued on a trial-by-trial basis to selectively deploy attention to the visual or auditory modality in anticipation of a target within the cued modality. Whereas typically developing (TD) children showed the predicted alpha-band modulation, with increased alpha-band power over parieto-occipital scalp when attention was deployed to the auditory compared with the visual modality, this differential pattern was entirely absent at the group level in the ASD cohort. Further, only the ASD group showed impaired performance due to the presence of task-irrelevant sensory information. These data suggest that impaired modulation of alpha-band activity plays a role in increased distraction from extraneous sensory inputs in ASD. En ligne : http://dx.doi.org/10.1002/aur.1374 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238