Detecting Social and Non-Social Changes in Natural Scenes: Performance of Children with and Without Autism Spectrum Disorders and Typical Adults / Bhavin R. SHETH in Journal of Autism and Developmental Disorders, 41-4 (April 2011)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 41-4 (April 2011) . - p.434-446 Titre : Detecting Social and Non-Social Changes in Natural Scenes: Performance of Children with and Without Autism Spectrum Disorders and Typical Adults Type de document : Texte imprimé et/ou numérique Auteurs : Bhavin R. SHETH, Auteur ; James LIU, Auteur ; Olayemi OLAGBAJU, Auteur ; Larry VARGHESE, Auteur ; Rosleen MANSOUR, Auteur ; Stacy REDDOCH, Auteur ; Deborah A. PEARSON, Auteur ; Katherine A. LOVELAND, Auteur Année de publication : 2011 Article en page(s) : p.434-446 Langues : Anglais (eng) Mots-clés : Social attention  Development  Change detection  Change blindness  Naturalistic scenes  Visual perception Index. décimale : PER Périodiques Résumé : We probed differences in the ability to detect and interpret social cues in adults and in children and young adolescents with and without autism spectrum disorders (ASD) by investigating the effect of various social and non-social contexts on the visual exploration of pictures of natural scenes. Children and adolescents relied more on social referencing cues in the scene as compared to adults, and in the presence of such cues, were less able to use other kinds of cues. Typically developing children and adolescents were no better than those with ASD at detecting changes within the various social contexts. Results suggest children and adolescents with ASD use relevant social cues while searching a scene just as typical children do. En ligne : http://dx.doi.org/10.1007/s10803-010-1062-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 [article] Detecting Social and Non-Social Changes in Natural Scenes: Performance of Children with and Without Autism Spectrum Disorders and Typical Adults [Texte imprimé et/ou numérique] / Bhavin R. SHETH, Auteur ; James LIU, Auteur ; Olayemi OLAGBAJU, Auteur ; Larry VARGHESE, Auteur ; Rosleen MANSOUR, Auteur ; Stacy REDDOCH, Auteur ; Deborah A. PEARSON, Auteur ; Katherine A. LOVELAND, Auteur . - 2011 . - p.434-446. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 41-4 (April 2011) . - p.434-446 Mots-clés : Social attention  Development  Change detection  Change blindness  Naturalistic scenes  Visual perception Index. décimale : PER Périodiques Résumé : We probed differences in the ability to detect and interpret social cues in adults and in children and young adolescents with and without autism spectrum disorders (ASD) by investigating the effect of various social and non-social contexts on the visual exploration of pictures of natural scenes. Children and adolescents relied more on social referencing cues in the scene as compared to adults, and in the presence of such cues, were less able to use other kinds of cues. Typically developing children and adolescents were no better than those with ASD at detecting changes within the various social contexts. Results suggest children and adolescents with ASD use relevant social cues while searching a scene just as typical children do. En ligne : http://dx.doi.org/10.1007/s10803-010-1062-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119

Executive Function in Autism: Association with ADHD and ASD Symptoms / Anthony R. WARD ; David M. LANE ; Michael G. AMAN ; Katherine A. LOVELAND ; Rosleen MANSOUR ; Deborah A. PEARSON in Journal of Autism and Developmental Disorders, 53-2 (February 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-2 (February 2023) . - p.688-700 Titre : Executive Function in Autism: Association with ADHD and ASD Symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Anthony R. WARD, Auteur ; David M. LANE, Auteur ; Michael G. AMAN, Auteur ; Katherine A. LOVELAND, Auteur ; Rosleen MANSOUR, Auteur ; Deborah A. PEARSON, Auteur Article en page(s) : p.688-700 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : There is substantial comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD), and there are well-documented executive functioning (EF) deficits in both populations. An important question concerns whether EF deficits in children with ASD are related to severity of ASD, ADHD, or both. We examined ADHD and ASD symptoms in relation to ratings of EF in the home and classroom. The sample comprised 64 children (55 males) diagnosed with ASD (mean age = 9.26 years; mean FSIQ = 92). Analyses indicated that parent and teacher ratings of EF (except Shift and Emotional Control) were consistently related to ADHD symptom severity, but not to ASD severity. Thus, functioning in the domains of Shift and Emotional control appear relatively spared, whereas performance in all other EF was impaired in relation to ADHD symptoms. En ligne : https://doi.org/10.1007/s10803-020-04852-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495 [article] Executive Function in Autism: Association with ADHD and ASD Symptoms [Texte imprimé et/ou numérique] / Anthony R. WARD, Auteur ; David M. LANE, Auteur ; Michael G. AMAN, Auteur ; Katherine A. LOVELAND, Auteur ; Rosleen MANSOUR, Auteur ; Deborah A. PEARSON, Auteur . - p.688-700. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-2 (February 2023) . - p.688-700 Index. décimale : PER Périodiques Résumé : There is substantial comorbidity between autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD), and there are well-documented executive functioning (EF) deficits in both populations. An important question concerns whether EF deficits in children with ASD are related to severity of ASD, ADHD, or both. We examined ADHD and ASD symptoms in relation to ratings of EF in the home and classroom. The sample comprised 64 children (55 males) diagnosed with ASD (mean age = 9.26 years; mean FSIQ = 92). Analyses indicated that parent and teacher ratings of EF (except Shift and Emotional Control) were consistently related to ADHD symptom severity, but not to ASD severity. Thus, functioning in the domains of Shift and Emotional control appear relatively spared, whereas performance in all other EF was impaired in relation to ADHD symptoms. En ligne : https://doi.org/10.1007/s10803-020-04852-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=495

Functional Assays of Local Connectivity in the Somatosensory Cortex of Individuals with Autism / Mehmet Akif COSKUN in Autism Research, 6-3 (June 2013)  

Public ISBD [article]  inAutism Research > 6-3 (June 2013) . - p.190-200 Titre : Functional Assays of Local Connectivity in the Somatosensory Cortex of Individuals with Autism Type de document : Texte imprimé et/ou numérique Auteurs : Mehmet Akif COSKUN, Auteur ; Katherine A. LOVELAND, Auteur ; Deborah A. PEARSON, Auteur ; Andrew C. PAPANICOLAOU, Auteur ; Bhavin R. SHETH, Auteur Année de publication : 2013 Article en page(s) : p.190-200 Langues : Anglais (eng) Mots-clés : connectivity  somatotopy  cortical inhibition  local excitation  tactile  homeostasis  touch  MEG Index. décimale : PER Périodiques Résumé : Emerging evidence for differences between individuals with autism spectrum disorder (ASD) and neurotypical (NT) individuals in somatic processing and brain response to touch suggests somatosensory cortex as a promising substrate for elucidating differences in functional brain connectivity between individuals with and without autism. Signals from adjacent digits project to neighboring locations or representations in somatosensory cortex. When a digit is stimulated, i.e. touched, its representation in cortex is directly activated; local intracortical connections indirectly activate nonprimary cortical representations corresponding to adjacent digits. The response of the nonprimary cortical representations is thus a proxy for connection strength. Local overconnectivity in autism implies that the nonprimary/primary response ratios of the ASD group will be higher than those of the NT group. D1 and D2 of the dominant hand of the participant were individually stimulated while we recorded neural responses using magnetoencephalography. The cortical representations of D1 and D2 (somatosensory-evoked fields) were computed from the ensemble-averaged data using (a) dipole model fits and (b) singular value decomposition. Individual adjacent/primary response ratios were measured, and group response ratio data were fitted with straight lines. Local overconnectivity in autism implies steeper ASD vs. NT group slopes. Our findings did not support local overconnectivity. Slopes were found to be significantly shallower for the ASD group than the NT group. Our findings support the idea of local underconnectivity in the somatosensory cortex of the brains of individuals with ASD. En ligne : http://dx.doi.org/10.1002/aur.1276 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202 [article] Functional Assays of Local Connectivity in the Somatosensory Cortex of Individuals with Autism [Texte imprimé et/ou numérique] / Mehmet Akif COSKUN, Auteur ; Katherine A. LOVELAND, Auteur ; Deborah A. PEARSON, Auteur ; Andrew C. PAPANICOLAOU, Auteur ; Bhavin R. SHETH, Auteur . - 2013 . - p.190-200. Langues : Anglais (eng) in Autism Research > 6-3 (June 2013) . - p.190-200 Mots-clés : connectivity  somatotopy  cortical inhibition  local excitation  tactile  homeostasis  touch  MEG Index. décimale : PER Périodiques Résumé : Emerging evidence for differences between individuals with autism spectrum disorder (ASD) and neurotypical (NT) individuals in somatic processing and brain response to touch suggests somatosensory cortex as a promising substrate for elucidating differences in functional brain connectivity between individuals with and without autism. Signals from adjacent digits project to neighboring locations or representations in somatosensory cortex. When a digit is stimulated, i.e. touched, its representation in cortex is directly activated; local intracortical connections indirectly activate nonprimary cortical representations corresponding to adjacent digits. The response of the nonprimary cortical representations is thus a proxy for connection strength. Local overconnectivity in autism implies that the nonprimary/primary response ratios of the ASD group will be higher than those of the NT group. D1 and D2 of the dominant hand of the participant were individually stimulated while we recorded neural responses using magnetoencephalography. The cortical representations of D1 and D2 (somatosensory-evoked fields) were computed from the ensemble-averaged data using (a) dipole model fits and (b) singular value decomposition. Individual adjacent/primary response ratios were measured, and group response ratio data were fitted with straight lines. Local overconnectivity in autism implies steeper ASD vs. NT group slopes. Our findings did not support local overconnectivity. Slopes were found to be significantly shallower for the ASD group than the NT group. Our findings support the idea of local underconnectivity in the somatosensory cortex of the brains of individuals with ASD. En ligne : http://dx.doi.org/10.1002/aur.1276 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=202

Improving the Reliability of Autism Diagnoses: Examining the Utility of Adaptive Behavior / Stacey S. TOMANIK in Journal of Autism and Developmental Disorders, 37-5 (May 2007)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 37-5 (May 2007) . - p.921-928 Titre : Improving the Reliability of Autism Diagnoses: Examining the Utility of Adaptive Behavior Type de document : Texte imprimé et/ou numérique Auteurs : Stacey S. TOMANIK, Auteur ; Deborah A. PEARSON, Auteur ; Katherine A. LOVELAND, Auteur ; David M. LANE, Auteur ; Bryant SHAW, Auteur Année de publication : 2007 Article en page(s) : p.921-928 Langues : Anglais (eng) Mots-clés : Autism-diagnosis Diagnostic-reliability Autism-spectrum-disorders Autism-Diagnostic-Interview-Revised-(ADI-R) Autism-Diagnostic-Observation-Schedule-(ADOS) Vineland Adaptive-functioning Index. décimale : PER Périodiques Résumé : The classification agreement of the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) was examined in 129 children and adolescents (aged 7–18 years) who were evaluated for autism. Participants received a diagnosis of autism or non-autism based on the ADI-R. Linear discriminant analysis revealed adequate concordance between the ADI-R and ADOS, with 75% of the participants being correctly classified using the ADOS. Classification accuracy significantly improved to 84% when a measure of adaptive functioning (i.e., the Vineland Adaptive Behavior Scales) was included in the analysis. The findings suggest that when clinicians obtain discrepant information on the ADI-R and ADOS, assessment of an individual’s adaptive functioning may reduce diagnostic errors. En ligne : http://dx.doi.org/10.1007/s10803-006-0227-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140 [article] Improving the Reliability of Autism Diagnoses: Examining the Utility of Adaptive Behavior [Texte imprimé et/ou numérique] / Stacey S. TOMANIK, Auteur ; Deborah A. PEARSON, Auteur ; Katherine A. LOVELAND, Auteur ; David M. LANE, Auteur ; Bryant SHAW, Auteur . - 2007 . - p.921-928. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 37-5 (May 2007) . - p.921-928 Mots-clés : Autism-diagnosis Diagnostic-reliability Autism-spectrum-disorders Autism-Diagnostic-Interview-Revised-(ADI-R) Autism-Diagnostic-Observation-Schedule-(ADOS) Vineland Adaptive-functioning Index. décimale : PER Périodiques Résumé : The classification agreement of the Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS) was examined in 129 children and adolescents (aged 7–18 years) who were evaluated for autism. Participants received a diagnosis of autism or non-autism based on the ADI-R. Linear discriminant analysis revealed adequate concordance between the ADI-R and ADOS, with 75% of the participants being correctly classified using the ADOS. Classification accuracy significantly improved to 84% when a measure of adaptive functioning (i.e., the Vineland Adaptive Behavior Scales) was included in the analysis. The findings suggest that when clinicians obtain discrepant information on the ADI-R and ADOS, assessment of an individual’s adaptive functioning may reduce diagnostic errors. En ligne : http://dx.doi.org/10.1007/s10803-006-0227-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=140

Interaction of Finger Representations in the Cortex of Individuals with Autism: A Functional Window into Cortical Inhibition / Mehmet Akif COSKUN in Autism Research, 6-6 (December 2013)  

Public ISBD [article]  inAutism Research > 6-6 (December 2013) . - p.542-549 Titre : Interaction of Finger Representations in the Cortex of Individuals with Autism: A Functional Window into Cortical Inhibition Type de document : Texte imprimé et/ou numérique Auteurs : Mehmet Akif COSKUN, Auteur ; Katherine A. LOVELAND, Auteur ; Deborah A. PEARSON, Auteur ; Andrew C. PAPANICOLAOU, Auteur ; Bhavin R. SHETH, Auteur Année de publication : 2013 Article en page(s) : p.542-549 Langues : Anglais (eng) Mots-clés : evoked potentials  homeostasis  somatosensory cortex  cortical interaction  finger representation  source modeling  tactile Index. décimale : PER Périodiques Résumé : An established neural biomarker of autism spectrum disorder (ASD) has the potential to provide novel biological and pharmacological targets for treatment. Lower level of inhibition in brain circuits is a leading biomarker candidate. A physiological investigation of the functional levels of inhibition in the cortex of individuals with autism can provide a strong test of the hypothesis. The amplitude of cortical response to the stimulation of adjacent fingers is controlled by the level of cortical inhibition and provides just such a test. Using magnetoencephalography, we recorded the response of the somatosensory cortex to the passive tactile stimulation of the thumb (D1), and index finger (D2), and to the simultaneous stimulation of both fingers combined (D1,D2) of the dominant (right) hand of young subjects with and without autism. For each participant, we measured the response to the stimulation of both fingers combined (D1,D2) relative to the post hoc sum of the responses to the stimulation of each finger alone (D1+D2) in multiple different ways and linearly regressed the ASD and neurotypical (NT) groups' responses. The resulting slopes were then compared: Smaller slope values imply attenuated response to paired finger stimulation, and enhanced levels of inhibition. The short-latency M40 and mid-latency M80 response slopes of the group with autism obtained in different ways were either significantly smaller, or statistically indistinguishable from NT. The result does not support reduced inhibition in the somatosensory cortex of individuals with autism, contrary to the seminal hypothesis of reduced inhibition. Implications are discussed including refinements of current theory. En ligne : http://dx.doi.org/10.1002/aur.1314 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 [article] Interaction of Finger Representations in the Cortex of Individuals with Autism: A Functional Window into Cortical Inhibition [Texte imprimé et/ou numérique] / Mehmet Akif COSKUN, Auteur ; Katherine A. LOVELAND, Auteur ; Deborah A. PEARSON, Auteur ; Andrew C. PAPANICOLAOU, Auteur ; Bhavin R. SHETH, Auteur . - 2013 . - p.542-549. Langues : Anglais (eng) in Autism Research > 6-6 (December 2013) . - p.542-549 Mots-clés : evoked potentials  homeostasis  somatosensory cortex  cortical interaction  finger representation  source modeling  tactile Index. décimale : PER Périodiques Résumé : An established neural biomarker of autism spectrum disorder (ASD) has the potential to provide novel biological and pharmacological targets for treatment. Lower level of inhibition in brain circuits is a leading biomarker candidate. A physiological investigation of the functional levels of inhibition in the cortex of individuals with autism can provide a strong test of the hypothesis. The amplitude of cortical response to the stimulation of adjacent fingers is controlled by the level of cortical inhibition and provides just such a test. Using magnetoencephalography, we recorded the response of the somatosensory cortex to the passive tactile stimulation of the thumb (D1), and index finger (D2), and to the simultaneous stimulation of both fingers combined (D1,D2) of the dominant (right) hand of young subjects with and without autism. For each participant, we measured the response to the stimulation of both fingers combined (D1,D2) relative to the post hoc sum of the responses to the stimulation of each finger alone (D1+D2) in multiple different ways and linearly regressed the ASD and neurotypical (NT) groups' responses. The resulting slopes were then compared: Smaller slope values imply attenuated response to paired finger stimulation, and enhanced levels of inhibition. The short-latency M40 and mid-latency M80 response slopes of the group with autism obtained in different ways were either significantly smaller, or statistically indistinguishable from NT. The result does not support reduced inhibition in the somatosensory cortex of individuals with autism, contrary to the seminal hypothesis of reduced inhibition. Implications are discussed including refinements of current theory. En ligne : http://dx.doi.org/10.1002/aur.1314 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221

Maternal and Paternal Age are Jointly Associated with Childhood Autism in Jamaica / Mohammad Hossein RAHBAR in Journal of Autism and Developmental Disorders, 42-9 (September 2012)  

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Measuring Anxiety as a Treatment Endpoint in Youth with Autism Spectrum Disorder / Luc LECAVALIER in Journal of Autism and Developmental Disorders, 44-5 (May 2014)  

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Measuring repetitive behaviors as a treatment endpoint in youth with autism spectrum disorder / Lawrence SCAHILL in Autism, 19-1 (January 2015)  

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Parent-reported problematic sleep behaviors in children with comorbid autism spectrum disorder and attention-deficit/hyperactivity disorder / Katharine C. REYNOLDS in Research in Autism Spectrum Disorders, 39 (July 2017)  

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Role of fruits, grains, and seafood consumption in blood cadmium concentrations of Jamaican children with and without Autism Spectrum Disorder / Mohammad H. RAHBAR in Research in Autism Spectrum Disorders, 8-9 (September 2014)  

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Role of parental occupation in autism spectrum disorder diagnosis and severity / Aisha S. DICKERSON in Research in Autism Spectrum Disorders, 8-9 (September 2014)  

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The diagnosis of autism and autism spectrum disorder in low- and middle-income countries: Experience from Jamaica / Maureen SAMMS-VAUGHAN in Autism, 21-5 (July 2017)  

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