A 20-year study of suicide death in a statewide autism population / A. V. KIRBY in Autism Research, 12-4 (April 2019)  

Public ISBD [article]  inAutism Research > 12-4 (April 2019) . - p.658-666 Titre : A 20-year study of suicide death in a statewide autism population Type de document : Texte imprimé et/ou numérique Auteurs : A. V. KIRBY, Auteur ; Amanda V. BAKIAN, Auteur ; Y. ZHANG, Auteur ; Deborah A. BILDER, Auteur ; B. R. KEESHIN, Auteur ; H. COON, Auteur Article en page(s) : p.658-666 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  epidemiology  mental health  population  suicide Index. décimale : PER Périodiques Résumé : SCIENTIFIC SUMMARY: Growing concern about suicide risk among individuals with autism spectrum disorder (ASD) necessitates population-based research to determine rates in representative samples and to inform appropriate prevention efforts. This study used existing surveillance data in Utah to determine incidence of suicide among individuals with ASD over a 20-year period, and to characterize those who died. Between 1998 and 2017, 49 individuals with ASD died by suicide. Suicide cumulative incidence rates did not significantly differ between 1998 and 2012 across the ASD and non-ASD populations. Between 2013 and 2017, the cumulative incidence of suicide in the ASD population was 0.17%, which was significantly higher than in the non-ASD population (0.11%; P < 0.05). During this period, this difference was driven by suicide among females with ASD; suicide risk in females with ASD was over three times higher than in females without ASD (relative risk (RR): 3.42; P < 0.01). Among the individuals with ASD who died by suicide, average age at death and manner of death did not differ significantly between males and females. Ages at death by suicide ranged from 14 to 70 years (M[SD] = 32.41[15.98]). Individuals with ASD were significantly less likely to use firearms as a method of suicide (adjusted odds ratio: 0.33; P < 0.001). Study results expand understanding of suicide risk in ASD and point to the need for additional population-based research into suicide attempts and ideation, as well as exploration of additional risk factors. Findings also suggest a need for further study of female suicide risk in ASD. Autism Research 2019, 12: 658-666. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: This study examined suicide risk among individuals with autism spectrum disorder (ASD) in Utah over a 20-year period. Risk of suicide death in individuals with ASD was found to have increased over time and to be greater than in individuals without ASD between 2013 and 2017. Females with ASD were over three times as likely to die from suicide as females without ASD. Young people with ASD were at over twice the risk of suicide than young people without ASD. Individuals with ASD were less likely than others to die from firearm-related suicides. En ligne : https://dx.doi.org/10.1002/aur.2076 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=389 [article] A 20-year study of suicide death in a statewide autism population [Texte imprimé et/ou numérique] / A. V. KIRBY, Auteur ; Amanda V. BAKIAN, Auteur ; Y. ZHANG, Auteur ; Deborah A. BILDER, Auteur ; B. R. KEESHIN, Auteur ; H. COON, Auteur . - p.658-666. Langues : Anglais (eng) in Autism Research > 12-4 (April 2019) . - p.658-666 Mots-clés : autism spectrum disorder  epidemiology  mental health  population  suicide Index. décimale : PER Périodiques Résumé : SCIENTIFIC SUMMARY: Growing concern about suicide risk among individuals with autism spectrum disorder (ASD) necessitates population-based research to determine rates in representative samples and to inform appropriate prevention efforts. This study used existing surveillance data in Utah to determine incidence of suicide among individuals with ASD over a 20-year period, and to characterize those who died. Between 1998 and 2017, 49 individuals with ASD died by suicide. Suicide cumulative incidence rates did not significantly differ between 1998 and 2012 across the ASD and non-ASD populations. Between 2013 and 2017, the cumulative incidence of suicide in the ASD population was 0.17%, which was significantly higher than in the non-ASD population (0.11%; P < 0.05). During this period, this difference was driven by suicide among females with ASD; suicide risk in females with ASD was over three times higher than in females without ASD (relative risk (RR): 3.42; P < 0.01). Among the individuals with ASD who died by suicide, average age at death and manner of death did not differ significantly between males and females. Ages at death by suicide ranged from 14 to 70 years (M[SD] = 32.41[15.98]). Individuals with ASD were significantly less likely to use firearms as a method of suicide (adjusted odds ratio: 0.33; P < 0.001). Study results expand understanding of suicide risk in ASD and point to the need for additional population-based research into suicide attempts and ideation, as well as exploration of additional risk factors. Findings also suggest a need for further study of female suicide risk in ASD. Autism Research 2019, 12: 658-666. (c) 2019 The Authors. Autism Research published by International Society for Autism Research published by Wiley Periodicals, Inc. LAY SUMMARY: This study examined suicide risk among individuals with autism spectrum disorder (ASD) in Utah over a 20-year period. Risk of suicide death in individuals with ASD was found to have increased over time and to be greater than in individuals without ASD between 2013 and 2017. Females with ASD were over three times as likely to die from suicide as females without ASD. Young people with ASD were at over twice the risk of suicide than young people without ASD. Individuals with ASD were less likely than others to die from firearm-related suicides. En ligne : https://dx.doi.org/10.1002/aur.2076 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=389

Antipsychotic Use and Metabolic Monitoring in Individuals with Developmental Disabilities Served in a Medicaid Medical Home / Lisa M. RUIZ in Journal of Autism and Developmental Disorders, 46-6 (June 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-6 (June 2016) . - p.1887-1894 Titre : Antipsychotic Use and Metabolic Monitoring in Individuals with Developmental Disabilities Served in a Medicaid Medical Home Type de document : Texte imprimé et/ou numérique Auteurs : Lisa M. RUIZ, Auteur ; Mackenzie DAMRON, Auteur ; Kyle B. JONES, Auteur ; Dean WEEDON, Auteur ; Paul S. CARBONE, Auteur ; Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur Article en page(s) : p.1887-1894 Langues : Anglais (eng) Mots-clés : Antipsychotics  Autism spectrum disorder  Intellectual disability  Medical home Index. décimale : PER Périodiques Résumé : This study describes antipsychotic use and metabolic monitoring rates among individuals with developmental disabilities enrolled in a subspecialty medical home (N = 826). Four hundred ninety-nine participants (60.4 %) were taking antipsychotics, which was associated with male gender (p = 0.01), intellectual disability with and without autism spectrum disorder (p = 0.001 and p = 0.04, respectively), and inversely associated with the youngest and oldest age categories (p = 0.001 and p = 0.04, respectively). Among those taking antipsychotics, annual metabolic monitoring rates ranged from 89 % (lipids) to 99 % (weight). Age was positively associated with glucose (p < 0.001) and lipid monitoring (p < 0.001). Adult participants with dyslipidemia (p < 0.01), prediabetes/diabetes (p = 0.04), and hypertension (p = 0.02) were significantly more likely to obtain lipid monitoring. These values exceeded previously reported rates suggesting the importance of an integrated care model. En ligne : http://dx.doi.org/10.1007/s10803-016-2712-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288 [article] Antipsychotic Use and Metabolic Monitoring in Individuals with Developmental Disabilities Served in a Medicaid Medical Home [Texte imprimé et/ou numérique] / Lisa M. RUIZ, Auteur ; Mackenzie DAMRON, Auteur ; Kyle B. JONES, Auteur ; Dean WEEDON, Auteur ; Paul S. CARBONE, Auteur ; Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur . - p.1887-1894. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-6 (June 2016) . - p.1887-1894 Mots-clés : Antipsychotics  Autism spectrum disorder  Intellectual disability  Medical home Index. décimale : PER Périodiques Résumé : This study describes antipsychotic use and metabolic monitoring rates among individuals with developmental disabilities enrolled in a subspecialty medical home (N = 826). Four hundred ninety-nine participants (60.4 %) were taking antipsychotics, which was associated with male gender (p = 0.01), intellectual disability with and without autism spectrum disorder (p = 0.001 and p = 0.04, respectively), and inversely associated with the youngest and oldest age categories (p = 0.001 and p = 0.04, respectively). Among those taking antipsychotics, annual metabolic monitoring rates ranged from 89 % (lipids) to 99 % (weight). Age was positively associated with glucose (p < 0.001) and lipid monitoring (p < 0.001). Adult participants with dyslipidemia (p < 0.01), prediabetes/diabetes (p = 0.04), and hypertension (p = 0.02) were significantly more likely to obtain lipid monitoring. These values exceeded previously reported rates suggesting the importance of an integrated care model. En ligne : http://dx.doi.org/10.1007/s10803-016-2712-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288

Autism Spectrum Disorder Reclassified: A Second Look at the 1980s Utah/UCLA Autism Epidemiologic Study / Judith S. MILLER in Journal of Autism and Developmental Disorders, 43-1 (January 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-1 (January 2013) . - p.200-210 Titre : Autism Spectrum Disorder Reclassified: A Second Look at the 1980s Utah/UCLA Autism Epidemiologic Study Type de document : Texte imprimé et/ou numérique Auteurs : Judith S. MILLER, Auteur ; Deborah A. BILDER, Auteur ; Megan A. FARLEY, Auteur ; Hilary H. COON, Auteur ; Judith PINBOROUGH-ZIMMERMAN, Auteur ; William R. JENSON, Auteur ; Catherine E. RICE, Auteur ; Eric FOMBONNE, Auteur ; Carmen B. PINGREE, Auteur ; Edward R. RITVO, Auteur ; Riva-Ariella RITVO, Auteur ; William M. MCMAHON, Auteur Année de publication : 2013 Article en page(s) : p.200-210 Langues : Anglais (eng) Mots-clés : Autism  Epidemiology  Prevalence  Diagnostic criteria  Intellectual disability Index. décimale : PER Périodiques Résumé : The purpose of the present study was to re-examine diagnostic data from a state-wide autism prevalence study (n = 489) conducted in the 1980s to investigate the impact of broader diagnostic criteria on autism spectrum disorder (ASD) case status. Sixty-four (59 %) of the 108 originally 'Diagnosed Not Autistic' met the current ASD case definition. The average IQ estimate in the newly identified group (IQ = 35.58; SD = 23.01) was significantly lower than in the original group (IQ = 56.19 SD = 21.21; t = 5.75; p .0001). Today's diagnostic criteria applied to participants ascertained in the 1980s identified more cases of autism with intellectual disability. The current analysis puts this historic work into context and highlights differences in ascertainment between epidemiological studies performed decades ago and those of today. En ligne : http://dx.doi.org/10.1007/s10803-012-1566-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187 [article] Autism Spectrum Disorder Reclassified: A Second Look at the 1980s Utah/UCLA Autism Epidemiologic Study [Texte imprimé et/ou numérique] / Judith S. MILLER, Auteur ; Deborah A. BILDER, Auteur ; Megan A. FARLEY, Auteur ; Hilary H. COON, Auteur ; Judith PINBOROUGH-ZIMMERMAN, Auteur ; William R. JENSON, Auteur ; Catherine E. RICE, Auteur ; Eric FOMBONNE, Auteur ; Carmen B. PINGREE, Auteur ; Edward R. RITVO, Auteur ; Riva-Ariella RITVO, Auteur ; William M. MCMAHON, Auteur . - 2013 . - p.200-210. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-1 (January 2013) . - p.200-210 Mots-clés : Autism  Epidemiology  Prevalence  Diagnostic criteria  Intellectual disability Index. décimale : PER Périodiques Résumé : The purpose of the present study was to re-examine diagnostic data from a state-wide autism prevalence study (n = 489) conducted in the 1980s to investigate the impact of broader diagnostic criteria on autism spectrum disorder (ASD) case status. Sixty-four (59 %) of the 108 originally 'Diagnosed Not Autistic' met the current ASD case definition. The average IQ estimate in the newly identified group (IQ = 35.58; SD = 23.01) was significantly lower than in the original group (IQ = 56.19 SD = 21.21; t = 5.75; p .0001). Today's diagnostic criteria applied to participants ascertained in the 1980s identified more cases of autism with intellectual disability. The current analysis puts this historic work into context and highlights differences in ascertainment between epidemiological studies performed decades ago and those of today. En ligne : http://dx.doi.org/10.1007/s10803-012-1566-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=187

Autism spectrum disorder reporting in lower socioeconomic neighborhoods / Aisha S. DICKERSON in Autism, 21-4 (May 2017)  

Public ISBD [article]  inAutism > 21-4 (May 2017) . - p.470-480 Titre : Autism spectrum disorder reporting in lower socioeconomic neighborhoods Type de document : Texte imprimé et/ou numérique Auteurs : Aisha S. DICKERSON, Auteur ; Mohammad H RAHBAR, Auteur ; Deborah A PEARSON, Auteur ; Russell S KIRBY, Auteur ; Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur ; Rebecca A HARRINGTON, Auteur ; Sydney PETTYGROVE, Auteur ; Walter ZAHORODNY, Auteur ; III LEMUEL A MOYÉ, Auteur ; Maureen DURKIN, Auteur ; Martha Slay WINGATE, Auteur Article en page(s) : p.470-480 Langues : Anglais (eng) Mots-clés : autism spectrum disorders  diagnosis  disparities  prevalence  school-age children Index. décimale : PER Périodiques Résumé : Utilizing surveillance data from five sites participating in the Autism and Developmental Disabilities Monitoring Network, we investigated contributions of surveillance subject and census tract population sociodemographic characteristics on variation in autism spectrum disorder ascertainment and prevalence estimates from 2000 to 2008 using ordinal hierarchical models for 2489 tracts. Multivariable analyses showed a significant increase in ascertainment of autism spectrum disorder cases through both school and health sources, the optimal ascertainment scenario, for cases with college-educated mothers (adjusted odds ratio?=?1.06, 95% confidence interval?=?1.02–1.09). Results from our examination of sociodemographic factors of tract populations from which cases were drawn also showed that after controlling for other covariates, statistical significance remained for associations between optimal ascertainment and percentage of Hispanic residents (adjusted odds ratio?=?0.93, 95% confidence interval?=?0.88–0.99) and percentage of residents with at least a bachelor’s degree (adjusted odds ratio?=?1.06, 95% confidence interval?=?1.01–1.11). We identified sociodemographic factors associated with autism spectrum disorder prevalence estimates including race, ethnicity, education, and income. Determining which specific factors influence disparities is complicated; however, it appears that even in the presence of education, racial and ethnic disparities are still apparent. These results suggest disparities in access to autism spectrum disorder assessments and special education for autism spectrum disorder among ethnic groups may impact subsequent surveillance. En ligne : http://dx.doi.org/10.1177/1362361316650091 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] Autism spectrum disorder reporting in lower socioeconomic neighborhoods [Texte imprimé et/ou numérique] / Aisha S. DICKERSON, Auteur ; Mohammad H RAHBAR, Auteur ; Deborah A PEARSON, Auteur ; Russell S KIRBY, Auteur ; Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur ; Rebecca A HARRINGTON, Auteur ; Sydney PETTYGROVE, Auteur ; Walter ZAHORODNY, Auteur ; III LEMUEL A MOYÉ, Auteur ; Maureen DURKIN, Auteur ; Martha Slay WINGATE, Auteur . - p.470-480. Langues : Anglais (eng) in Autism > 21-4 (May 2017) . - p.470-480 Mots-clés : autism spectrum disorders  diagnosis  disparities  prevalence  school-age children Index. décimale : PER Périodiques Résumé : Utilizing surveillance data from five sites participating in the Autism and Developmental Disabilities Monitoring Network, we investigated contributions of surveillance subject and census tract population sociodemographic characteristics on variation in autism spectrum disorder ascertainment and prevalence estimates from 2000 to 2008 using ordinal hierarchical models for 2489 tracts. Multivariable analyses showed a significant increase in ascertainment of autism spectrum disorder cases through both school and health sources, the optimal ascertainment scenario, for cases with college-educated mothers (adjusted odds ratio?=?1.06, 95% confidence interval?=?1.02–1.09). Results from our examination of sociodemographic factors of tract populations from which cases were drawn also showed that after controlling for other covariates, statistical significance remained for associations between optimal ascertainment and percentage of Hispanic residents (adjusted odds ratio?=?0.93, 95% confidence interval?=?0.88–0.99) and percentage of residents with at least a bachelor’s degree (adjusted odds ratio?=?1.06, 95% confidence interval?=?1.01–1.11). We identified sociodemographic factors associated with autism spectrum disorder prevalence estimates including race, ethnicity, education, and income. Determining which specific factors influence disparities is complicated; however, it appears that even in the presence of education, racial and ethnic disparities are still apparent. These results suggest disparities in access to autism spectrum disorder assessments and special education for autism spectrum disorder among ethnic groups may impact subsequent surveillance. En ligne : http://dx.doi.org/10.1177/1362361316650091 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site / Amanda V. BAKIAN in Journal of Autism and Developmental Disorders, 45-3 (March 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.873-880 Titre : Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site Type de document : Texte imprimé et/ou numérique Auteurs : Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur ; Paul S. CARBONE, Auteur ; Tyler D. HUNT, Auteur ; Brent PETERSEN, Auteur ; Catherine E. RICE, Auteur Article en page(s) : p.873-880 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autism and Developmental Disabilities Monitoring Network  ASD surveillance  ASD prevalence  Validation  DSM-IV-TR Index. décimale : PER Périodiques Résumé : An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network’s (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74–0.90)], and sensitivity [0.99 (95 % CI 0.96–1.00)] were high for ASD case versus non-case classification between UT-ADDM and EER. At least one EER disagreed with UT-ADDM on ASD final case status on nine out of 30 records; however, all three EERs disagreed with UT-ADDM for only one record. Findings based on limited data suggest that children with ASD as identified by UT-ADDM are consistently classified as ASD cases by independent autism experts. En ligne : http://dx.doi.org/10.1007/s10803-014-2187-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258 [article] Brief Report: Independent Validation of Autism Spectrum Disorder Case Status in the Utah Autism and Developmental Disabilities Monitoring (ADDM) Network Site [Texte imprimé et/ou numérique] / Amanda V. BAKIAN, Auteur ; Deborah A. BILDER, Auteur ; Paul S. CARBONE, Auteur ; Tyler D. HUNT, Auteur ; Brent PETERSEN, Auteur ; Catherine E. RICE, Auteur . - p.873-880. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-3 (March 2015) . - p.873-880 Mots-clés : Autism spectrum disorder  Autism and Developmental Disabilities Monitoring Network  ASD surveillance  ASD prevalence  Validation  DSM-IV-TR Index. décimale : PER Périodiques Résumé : An independent validation was conducted of the Utah Autism and Developmental Disabilities Monitoring Network’s (UT-ADDM) classification of children with autism spectrum disorder (ASD). UT-ADDM final case status (n = 90) was compared with final case status as determined by independent external expert reviewers (EERs). Inter-rater reliability (ICC = 0.84), specificity [0.83 (95 % CI 0.74–0.90)], and sensitivity [0.99 (95 % CI 0.96–1.00)] were high for ASD case versus non-case classification between UT-ADDM and EER. At least one EER disagreed with UT-ADDM on ASD final case status on nine out of 30 records; however, all three EERs disagreed with UT-ADDM for only one record. Findings based on limited data suggest that children with ASD as identified by UT-ADDM are consistently classified as ASD cases by independent autism experts. En ligne : http://dx.doi.org/10.1007/s10803-014-2187-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=258

Brief Report: The Prevalence of Neurofibromatosis Type 1 among Children with Autism Spectrum Disorder Identified by the Autism and Developmental Disabilities Monitoring Network / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 46-10 (October 2016)  

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Changes in the Administrative Prevalence of Autism Spectrum Disorders: Contribution of Special Education and Health from 2002–2008 / Judith PINBOROUGH-ZIMMERMAN in Journal of Autism and Developmental Disorders, 42-4 (April 2012)  

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Combined genome-wide linkage and targeted association analysis of head circumference in autism spectrum disorder families / M. WOODBURY-SMITH in Journal of Neurodevelopmental Disorders, 9-1 (December 2017)  

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Correction to: Early Second Trimester Maternal Serum SteroidRelated Biomarkers Associated with Autism Spectrum Disorder / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 49-11 (November 2019)  

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A description of medical conditions in adults with autism spectrum disorder: A follow-up of the 1980s Utah/UCLA Autism Epidemiologic Study / Kyle B. JONES in Autism, 20-5 (July 2016)  

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Early Second Trimester Maternal Serum Steroid-Related Biomarkers Associated with Autism Spectrum Disorder / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 49-11 (November 2019)  

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Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study / Deborah A. BILDER in Journal of Autism and Developmental Disorders, 43-5 (May 2013)  

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Mid?life social outcomes for a population?based sample of adults with ASD / Megan FARLEY in Autism Research, 11-1 (January 2018)  

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Psychiatric Comorbidity and Medication Use in Adults with Autism Spectrum Disorder / Tara R. BUCK in Journal of Autism and Developmental Disorders, 44-12 (December 2014)  

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Regional differences in autism and intellectual disability risk associated with cesarean section delivery / Deborah A. BILDER in Autism Research, 17-11 (November 2024)  

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