[article] 
inJournal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2602-2607

Titre :	Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations?
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Joseph M. BRAUN, Auteur ; Tanya FROEHLICH, Auteur ; Amy E. KALKBRENNER, Auteur ; Christine M. PFEIFFER, Auteur ; Zia FAZILI, Auteur ; Kimberly YOLTON, Auteur ; Bruce P. LANPHEAR, Auteur
Article en page(s) :	p.2602-2607
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorders  Folate  Pregnancy  Prenatal vitamins
Index. décimale :	PER Périodiques
Résumé :	Prenatal multivitamin/folic acid supplement use may reduce the risk of autism spectrum disorders. We investigated whether 2nd trimester prenatal vitamin use and maternal whole blood folate (WBF) concentrations were associated with Social Responsiveness Scale (SRS) scores at 4–5 years of age in a prospective cohort of 209 mother–child pairs. After confounder adjustment, children born to women taking prenatal vitamins weekly/daily (n = 179) had lower odds of clinically elevated SRS scores (odds ratio 0.26; 95 % confidence interval 0.08, 0.89) than those who rarely/never took them (n = 30). WBF concentrations were not associated with SRS scores. The lack of association between WBF and autistic-behaviors may be due to the timing of biomarker measures relative to critical periods of brain development, confounding, or other modifying factors.
En ligne :	http://dx.doi.org/10.1007/s10803-014-2114-x
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240

[article] Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations? [Texte imprimé et/ou numérique] / Joseph M. BRAUN, Auteur ; Tanya FROEHLICH, Auteur ; Amy E. KALKBRENNER, Auteur ; Christine M. PFEIFFER, Auteur ; Zia FAZILI, Auteur ; Kimberly YOLTON, Auteur ; Bruce P. LANPHEAR, Auteur . - p.2602-2607.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 44-10 (October 2014) . - p.2602-2607

Mots-clés :	Autism spectrum disorders  Folate  Pregnancy  Prenatal vitamins
Index. décimale :	PER Périodiques
Résumé :	Prenatal multivitamin/folic acid supplement use may reduce the risk of autism spectrum disorders. We investigated whether 2nd trimester prenatal vitamin use and maternal whole blood folate (WBF) concentrations were associated with Social Responsiveness Scale (SRS) scores at 4–5 years of age in a prospective cohort of 209 mother–child pairs. After confounder adjustment, children born to women taking prenatal vitamins weekly/daily (n = 179) had lower odds of clinically elevated SRS scores (odds ratio 0.26; 95 % confidence interval 0.08, 0.89) than those who rarely/never took them (n = 30). WBF concentrations were not associated with SRS scores. The lack of association between WBF and autistic-behaviors may be due to the timing of biomarker measures relative to critical periods of brain development, confounding, or other modifying factors.
En ligne :	http://dx.doi.org/10.1007/s10803-014-2114-x
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=240