Brief Report: Is Cognitive Rehabilitation Needed in Verbal Adults with Autism? Insights from Initial Enrollment in a Trial of Cognitive Enhancement Therapy / Shaun M. EACK in Journal of Autism and Developmental Disorders, 43-9 (September 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2233-2237 Titre : Brief Report: Is Cognitive Rehabilitation Needed in Verbal Adults with Autism? Insights from Initial Enrollment in a Trial of Cognitive Enhancement Therapy Type de document : texte imprimé Auteurs : Shaun M. EACK, Auteur ; Amber L. BAHORIK, Auteur ; Susan S. HOGARTY, Auteur ; Deborah P. GREENWALD, Auteur ; Maralee Y. LITSCHGE, Auteur ; Carla A. MAZEFSKY, Auteur ; Nancy J. MINSHEW, Auteur Article en page(s) : p.2233-2237 Langues : Anglais (eng) Mots-clés : Cognition  Social cognition  Neurocognition  Cognitive rehabilitation  Adults Index. décimale : PER Périodiques Résumé : Cognitive rehabilitation is an emerging set of potentially effective interventions for the treatment of autism spectrum disorder, yet the applicability of these approaches for “high functioning” adults who have normative levels of intelligence remains unexplored. This study examined the initial cognitive performance characteristics of 40 verbal adults with autism enrolled in a pilot trial of Cognitive Enhancement Therapy to investigate the need for cognitive rehabilitation in this population. Results revealed marked and broad deficits across neurocognitive and social-cognitive domains, despite above-average IQ. Areas of greatest impairment included processing speed, cognitive flexibility, and emotion perception and management. These findings indicate the need for comprehensive interventions designed to enhance cognition among verbal adults with autism who have intact intellectual functioning. En ligne : http://dx.doi.org/10.1007/s10803-013-1774-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212 [article] Brief Report: Is Cognitive Rehabilitation Needed in Verbal Adults with Autism? Insights from Initial Enrollment in a Trial of Cognitive Enhancement Therapy [texte imprimé] / Shaun M. EACK, Auteur ; Amber L. BAHORIK, Auteur ; Susan S. HOGARTY, Auteur ; Deborah P. GREENWALD, Auteur ; Maralee Y. LITSCHGE, Auteur ; Carla A. MAZEFSKY, Auteur ; Nancy J. MINSHEW, Auteur . - p.2233-2237. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-9 (September 2013) . - p.2233-2237 Mots-clés : Cognition  Social cognition  Neurocognition  Cognitive rehabilitation  Adults Index. décimale : PER Périodiques Résumé : Cognitive rehabilitation is an emerging set of potentially effective interventions for the treatment of autism spectrum disorder, yet the applicability of these approaches for “high functioning” adults who have normative levels of intelligence remains unexplored. This study examined the initial cognitive performance characteristics of 40 verbal adults with autism enrolled in a pilot trial of Cognitive Enhancement Therapy to investigate the need for cognitive rehabilitation in this population. Results revealed marked and broad deficits across neurocognitive and social-cognitive domains, despite above-average IQ. Areas of greatest impairment included processing speed, cognitive flexibility, and emotion perception and management. These findings indicate the need for comprehensive interventions designed to enhance cognition among verbal adults with autism who have intact intellectual functioning. En ligne : http://dx.doi.org/10.1007/s10803-013-1774-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=212

Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18-month randomized clinical trial / Shaun M. EACK in Autism Research, 11-3 (March 2018)  

Public ISBD [article]  inAutism Research > 11-3 (March 2018) . - p.519-530 Titre : Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18-month randomized clinical trial Type de document : texte imprimé Auteurs : Shaun M. EACK, Auteur ; Susan S. HOGARTY, Auteur ; Deborah P. GREENWALD, Auteur ; Maralee Y. LITSCHGE, Auteur ; Shannondora A. PORTON, Auteur ; Carla A. MAZEFSKY, Auteur ; Nancy J. MINSHEW, Auteur Article en page(s) : p.519-530 Langues : Anglais (eng) Mots-clés : adult autism  cognitive enhancement  cognitive remediation  neurocognition  social cognition Index. décimale : PER Périodiques Résumé : Cognitive remediation is a promising approach to treating core cognitive deficits in adults with autism, but rigorously controlled trials of comprehensive interventions that target both social and non-social cognition over a sufficient period of time to impact functioning are lacking. This study examined the efficacy of cognitive enhancement therapy (CET) for improving core cognitive and employment outcomes in adult autism. Verbal adult outpatients with autism spectrum disorder (N = 54) were randomized to an 18-month, single-blind trial of CET, a cognitive remediation approach that integrates computer-based neurocognitive training with group-based training in social cognition, or an active enriched supportive therapy (EST) comparison focused on psychoeducation and condition management. Primary outcomes were composite indexes of neurocognitive and social-cognitive change. Competitive employment was a secondary outcome. Intent-to-treat analyses indicated that CET produced significant differential increases in neurocognitive function relative to EST (d = .46, P = .013). Both CET and EST were associated with large social-cognitive improvements, with CET demonstrating an advantage at 9 (d = .58, P = 0.020), but not 18 months (d = .27, P = 0.298). Effects on employment indicated that participants treated with CET were significantly more likely to gain competitive employment than those in EST, OR = 6.21, P = 0.023, which was mediated by cognitive improvement. CET is a feasible and potentially effective treatment for core cognitive deficits in adult autism spectrum disorder. The treatment of cognitive impairments in this population can contribute to meaningful improvements in adult outcomes. Autism Res 2018, 11: 519-530. (c) 2017 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Cognitive enhancement therapy (CET), an 18-month cognitive remediation intervention designed to improve thinking and social understanding, was found to be more effective than supportive therapy at improving mental quickness, attention, and employment in adults living with autism. Social understanding was equally improved in CET and supportive therapy. Cognitive remediation interventions are feasible and may confer significant functional benefits to adults with autism. En ligne : http://dx.doi.org/10.1002/aur.1913 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=352 [article] Cognitive enhancement therapy for adult autism spectrum disorder: Results of an 18-month randomized clinical trial [texte imprimé] / Shaun M. EACK, Auteur ; Susan S. HOGARTY, Auteur ; Deborah P. GREENWALD, Auteur ; Maralee Y. LITSCHGE, Auteur ; Shannondora A. PORTON, Auteur ; Carla A. MAZEFSKY, Auteur ; Nancy J. MINSHEW, Auteur . - p.519-530. Langues : Anglais (eng) in Autism Research > 11-3 (March 2018) . - p.519-530 Mots-clés : adult autism  cognitive enhancement  cognitive remediation  neurocognition  social cognition Index. décimale : PER Périodiques Résumé : Cognitive remediation is a promising approach to treating core cognitive deficits in adults with autism, but rigorously controlled trials of comprehensive interventions that target both social and non-social cognition over a sufficient period of time to impact functioning are lacking. This study examined the efficacy of cognitive enhancement therapy (CET) for improving core cognitive and employment outcomes in adult autism. Verbal adult outpatients with autism spectrum disorder (N = 54) were randomized to an 18-month, single-blind trial of CET, a cognitive remediation approach that integrates computer-based neurocognitive training with group-based training in social cognition, or an active enriched supportive therapy (EST) comparison focused on psychoeducation and condition management. Primary outcomes were composite indexes of neurocognitive and social-cognitive change. Competitive employment was a secondary outcome. Intent-to-treat analyses indicated that CET produced significant differential increases in neurocognitive function relative to EST (d = .46, P = .013). Both CET and EST were associated with large social-cognitive improvements, with CET demonstrating an advantage at 9 (d = .58, P = 0.020), but not 18 months (d = .27, P = 0.298). Effects on employment indicated that participants treated with CET were significantly more likely to gain competitive employment than those in EST, OR = 6.21, P = 0.023, which was mediated by cognitive improvement. CET is a feasible and potentially effective treatment for core cognitive deficits in adult autism spectrum disorder. The treatment of cognitive impairments in this population can contribute to meaningful improvements in adult outcomes. Autism Res 2018, 11: 519-530. (c) 2017 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Cognitive enhancement therapy (CET), an 18-month cognitive remediation intervention designed to improve thinking and social understanding, was found to be more effective than supportive therapy at improving mental quickness, attention, and employment in adults living with autism. Social understanding was equally improved in CET and supportive therapy. Cognitive remediation interventions are feasible and may confer significant functional benefits to adults with autism. En ligne : http://dx.doi.org/10.1002/aur.1913 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=352

Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-month Feasibility Study / Shaun M. EACK in Journal of Autism and Developmental Disorders, 43-12 (December 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2866-2877 Titre : Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-month Feasibility Study Type de document : texte imprimé Auteurs : Shaun M. EACK, Auteur ; Deborah P. GREENWALD, Auteur ; Susan S. HOGARTY, Auteur ; Amber L. BAHORIK, Auteur ; Maralee Y. LITSCHGE, Auteur ; Carla A. MAZEFSKY, Auteur ; Nancy J. MINSHEW, Auteur Article en page(s) : p.2866-2877 Langues : Anglais (eng) Mots-clés : Cognitive Enhancement Therapy  Cognitive rehabilitation  Cognitive remediation  Psychosocial treatment  Cognitive therapy  Adult treatment  Autism  Autism spectrum disorder Index. décimale : PER Périodiques Résumé : Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to investigate its feasibility, acceptability, and initial efficacy in treating these impairments. Results indicated that CET was satisfying to participants, with high treatment attendance and retention. Effects on cognitive deficits and social behavior were also large (d = 1.40–2.29) and statistically significant (all p .001). These findings suggest that CET is a feasible, acceptable, and potentially effective intervention for remediating the social and non-social cognitive impairments in verbal adults with autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1834-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218 [article] Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-month Feasibility Study [texte imprimé] / Shaun M. EACK, Auteur ; Deborah P. GREENWALD, Auteur ; Susan S. HOGARTY, Auteur ; Amber L. BAHORIK, Auteur ; Maralee Y. LITSCHGE, Auteur ; Carla A. MAZEFSKY, Auteur ; Nancy J. MINSHEW, Auteur . - p.2866-2877. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-12 (December 2013) . - p.2866-2877 Mots-clés : Cognitive Enhancement Therapy  Cognitive rehabilitation  Cognitive remediation  Psychosocial treatment  Cognitive therapy  Adult treatment  Autism  Autism spectrum disorder Index. décimale : PER Périodiques Résumé : Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to investigate its feasibility, acceptability, and initial efficacy in treating these impairments. Results indicated that CET was satisfying to participants, with high treatment attendance and retention. Effects on cognitive deficits and social behavior were also large (d = 1.40–2.29) and statistically significant (all p .001). These findings suggest that CET is a feasible, acceptable, and potentially effective intervention for remediating the social and non-social cognitive impairments in verbal adults with autism. En ligne : http://dx.doi.org/10.1007/s10803-013-1834-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=218

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