Contributions of magnetic resonance spectroscopy to understanding development: Potential applications in the study of adolescent alcohol use and abuse / Julia E. COHEN-GILBERT in Development and Psychopathology, 26-2 (May 2014)  

Public ISBD [article]  inDevelopment and Psychopathology > 26-2 (May 2014) . - p.405-423 Titre : Contributions of magnetic resonance spectroscopy to understanding development: Potential applications in the study of adolescent alcohol use and abuse Type de document : Texte imprimé et/ou numérique Auteurs : Julia E. COHEN-GILBERT, Auteur ; J. Eric JENSEN, Auteur ; Marisa M. SILVERI, Auteur Article en page(s) : p.405-423 Index. décimale : PER Périodiques Résumé : A growing body of research has documented structural and functional brain development during adolescence, yet little is known about neurochemical changes that occur during this important developmental period. Magnetic resonance spectroscopy (MRS) is a well-developed technology that permits the in vivo quantification of multiple brain neurochemicals relevant to neuronal health and functioning. However, MRS technology has been underused in exploring normative developmental changes during adolescence and the onset of alcohol and drug use and abuse during this developmental period. This review begins with a brief overview of normative cognitive and neurobiological development during adolescence, followed by an introduction to MRS principles. The subsequent sections provide a comprehensive review of the existing MRS studies of development and cognitive functioning in healthy children and adolescents. The final sections of this article address the potential application of MRS in identifying neurochemical predictors and consequences of alcohol use and abuse in adolescence. MRS studies of adolescent populations hold promise for advancing our understanding of neurobiological risk factors for psychopathology by identifying the biochemical signatures associated with healthy brain development, as well as neurobiological and cognitive correlates of alcohol and substance use and abuse. En ligne : http://dx.doi.org/10.1017/S0954579414000030 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=230 [article] Contributions of magnetic resonance spectroscopy to understanding development: Potential applications in the study of adolescent alcohol use and abuse [Texte imprimé et/ou numérique] / Julia E. COHEN-GILBERT, Auteur ; J. Eric JENSEN, Auteur ; Marisa M. SILVERI, Auteur . - p.405-423. in Development and Psychopathology > 26-2 (May 2014) . - p.405-423 Index. décimale : PER Périodiques Résumé : A growing body of research has documented structural and functional brain development during adolescence, yet little is known about neurochemical changes that occur during this important developmental period. Magnetic resonance spectroscopy (MRS) is a well-developed technology that permits the in vivo quantification of multiple brain neurochemicals relevant to neuronal health and functioning. However, MRS technology has been underused in exploring normative developmental changes during adolescence and the onset of alcohol and drug use and abuse during this developmental period. This review begins with a brief overview of normative cognitive and neurobiological development during adolescence, followed by an introduction to MRS principles. The subsequent sections provide a comprehensive review of the existing MRS studies of development and cognitive functioning in healthy children and adolescents. The final sections of this article address the potential application of MRS in identifying neurochemical predictors and consequences of alcohol use and abuse in adolescence. MRS studies of adolescent populations hold promise for advancing our understanding of neurobiological risk factors for psychopathology by identifying the biochemical signatures associated with healthy brain development, as well as neurobiological and cognitive correlates of alcohol and substance use and abuse. En ligne : http://dx.doi.org/10.1017/S0954579414000030 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=230

Impact of childhood maltreatment and resilience on behavioral and neural patterns of inhibitory control during emotional distraction / Lauren A. DEMERS in Development and Psychopathology, 34-4 (October 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-4 (October 2022) . - p.1260-1271 Titre : Impact of childhood maltreatment and resilience on behavioral and neural patterns of inhibitory control during emotional distraction Type de document : Texte imprimé et/ou numérique Auteurs : Lauren A. DEMERS, Auteur ; Ruskin H. HUNT, Auteur ; Dante CICCHETTI, Auteur ; Julia E. COHEN-GILBERT, Auteur ; Fred A. ROGOSCH, Auteur ; Sheree L. TOTH, Auteur ; Kathleen M. THOMAS, Auteur Article en page(s) : p.1260-1271 Langues : Anglais (eng) Mots-clés : Adult  Attention  Brain/diagnostic imaging  Child  Child Abuse/psychology  Emotional Regulation  Emotions/physiology  Humans  Magnetic Resonance Imaging  childhood maltreatment  emotion  impulsivity  inhibitory control  prefrontal cortex  interest. Index. décimale : PER Périodiques Résumé : Exposure to childhood maltreatment (CM) may disrupt typical development of neural systems underlying impulse control and emotion regulation. Yet resilient outcomes are observed in some individuals exposed to CM. Individual differences in adult functioning may result from variation in inhibitory control in the context of emotional distractions, underpinned by cognitive-affective brain circuits. Thirty-eight healthy adults with a history of substantiated CM and 34 nonmaltreated adults from the same longitudinal sample performed a Go/No-Go task in which task-relevant stimuli (letters) were presented at the center of task-irrelevant, negative, or neutral images, while undergoing functional magnetic resonance imaging. The comparison group, but not the maltreated group, made increased inhibitory control errors in the context of negative, but not neutral, distractor images. In addition, the comparison group had greater right inferior frontal gyrus and bilateral frontal pole activation during inhibitory control blocks with negative compared to neutral background images relative to the CM group. Across the full sample, greater adaptive functioning in everyday contexts was associated with superior inhibitory control and greater right frontal pole activation. Results suggest that resilience following early adversity is associated with enhanced attention and behavioral regulation in the context of task-irrelevant negative emotional stimuli in a laboratory setting. En ligne : http://dx.doi.org/10.1017/s0954579421000055 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 [article] Impact of childhood maltreatment and resilience on behavioral and neural patterns of inhibitory control during emotional distraction [Texte imprimé et/ou numérique] / Lauren A. DEMERS, Auteur ; Ruskin H. HUNT, Auteur ; Dante CICCHETTI, Auteur ; Julia E. COHEN-GILBERT, Auteur ; Fred A. ROGOSCH, Auteur ; Sheree L. TOTH, Auteur ; Kathleen M. THOMAS, Auteur . - p.1260-1271. Langues : Anglais (eng) in Development and Psychopathology > 34-4 (October 2022) . - p.1260-1271 Mots-clés : Adult  Attention  Brain/diagnostic imaging  Child  Child Abuse/psychology  Emotional Regulation  Emotions/physiology  Humans  Magnetic Resonance Imaging  childhood maltreatment  emotion  impulsivity  inhibitory control  prefrontal cortex  interest. Index. décimale : PER Périodiques Résumé : Exposure to childhood maltreatment (CM) may disrupt typical development of neural systems underlying impulse control and emotion regulation. Yet resilient outcomes are observed in some individuals exposed to CM. Individual differences in adult functioning may result from variation in inhibitory control in the context of emotional distractions, underpinned by cognitive-affective brain circuits. Thirty-eight healthy adults with a history of substantiated CM and 34 nonmaltreated adults from the same longitudinal sample performed a Go/No-Go task in which task-relevant stimuli (letters) were presented at the center of task-irrelevant, negative, or neutral images, while undergoing functional magnetic resonance imaging. The comparison group, but not the maltreated group, made increased inhibitory control errors in the context of negative, but not neutral, distractor images. In addition, the comparison group had greater right inferior frontal gyrus and bilateral frontal pole activation during inhibitory control blocks with negative compared to neutral background images relative to the CM group. Across the full sample, greater adaptive functioning in everyday contexts was associated with superior inhibitory control and greater right frontal pole activation. Results suggest that resilience following early adversity is associated with enhanced attention and behavioral regulation in the context of task-irrelevant negative emotional stimuli in a laboratory setting. En ligne : http://dx.doi.org/10.1017/s0954579421000055 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488

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